North East Fund

Nanovery Limited, based in London, United Kingdom, specializes in the development of nanorobots aimed at detecting cancer mutations. Incorporated in 2018, the company leverages advances in nanotechnology, medicinal chemistry, and artificial intelligence to create a platform that enables rapid and sensitive identification of challenging disease biomarkers. These nanorobots are designed to be introduced into blood samples, where they capture circulating tumor DNA and emit a fluorescent signal, facilitating point-of-care detection. This innovative approach not only aids in the early detection of cancer but also enhances the ability to predict the evolution of cancer cells, significantly improving the chances of patient survival. Supported by academic experts, clinicians, and industry leaders, Nanovery is committed to making cancer detection more efficient and accessible.

Aelius Biotech specializes in developing advanced models of the mucosal surfaces of the human body, including the gastrointestinal tract and airways. The company is actively working on creating model systems for the eye and cervico-vaginal tract. Aelius Biotech provides a comprehensive range of in vitro and in vivo testing services, including simple lab assays, routine testing, and rheology. Their integrated model gut system allows healthcare industry participants to simulate key processes such as digestion, mucus permeation, and epithelial absorption in one cohesive platform. By conducting human trials and offering detailed insights, Aelius Biotech aids healthcare companies in making informed, data-driven decisions to enhance and de-risk the development of orally delivered products.

Circadacare is a health technology company focused on enhancing the quality of life for older adults in care environments. By leveraging scientific principles, the company offers innovative lighting solutions that synchronize with the natural day-night cycle, improving the well-being of residents while also benefiting staff. Their integrated system combines lighting, sensors, and software technology to create an optimal care setting that fosters mood and engagement. Circadacare aims to simplify operations for care providers, ensuring that their systems function seamlessly without requiring extensive training or intervention from staff. This approach not only enhances care outcomes for residents but also offers cost benefits to operators of nursing homes, care villages, and dementia care centers.

onHand is an on-demand volunteering platform designed to simplify the process of engaging in volunteer work. By connecting individuals seeking assistance with those willing to help, the platform allows users to easily find and participate in local micro-volunteering opportunities. It facilitates access to verified volunteers and offers a streamlined approach to eco and social initiatives, making volunteering as straightforward as ordering food online. Through its innovative model, onHand aims to provide high-impact experiences for volunteers while supporting charities and local projects in need of assistance.

Newcells Biotech Limited is a biotechnology company specializing in the production of induced pluripotent stem cells (iPSCs) and their differentiation into various cell and tissue types for research and development purposes. Founded in 2014 and based in Newcastle upon Tyne, United Kingdom, the company offers a diverse portfolio of off-the-shelf iPSC-derived cell lines, including custom iPSCs generated from patient tissues, neural progenitor cells, cardiomyocytes, and various somatic cell types. Newcells Biotech focuses on providing high-quality cells and development services, including tissue sourcing and bespoke differentiation, to support customers engaged in drug discovery, pre-clinical development, and disease mechanism investigation. The company's platform also aims to create in vitro cell-based assays that closely replicate human physiology, enhancing the prediction of safety, pharmacology, and efficacy in drug testing.

AMLo Biosciences Ltd is a biotechnology company based in Newcastle upon Tyne, United Kingdom, focused on developing diagnostic solutions for melanoma. Incorporated in 2017, the company has created a diagnostic kit that utilizes the AMBLor test, which accurately predicts the risk of disease progression in patients with early AJCC Stage I and Stage II melanoma. This test identifies two specific proteins in the skin overlying the primary tumor that are typically lost in high-risk melanoma cases. By providing a reliable prognostic assessment, AMLo aims to help stratify patients for appropriate treatment and follow-up, ultimately reducing the psychological burden on patients and decreasing healthcare costs associated with unnecessary surveillance.

FAT32 is a technology company specializing in compliance automation. It develops a platform that continuously monitors and assesses a business's infrastructure and tools to ensure they remain compliant with relevant regulations. The platform also automatically identifies and manages shadow IT applications, generating custom reports to help businesses meet regulatory demands efficiently.

NunaBio is a privately-owned specialist DNA development company based in England, United Kingdom. The company focuses on chemical and biological technologies, providing a diverse array of products and services, including long and short deoxyribonucleic acid products available in various scales, from microgram to gram. NunaBio is involved in contract research and development, as well as manufacturing, offering capabilities in cell therapies, vaccines, diagnostics, gene therapies, and advanced DNA biosensing. By delivering these innovative solutions, NunaBio aims to support healthcare professionals in their efforts to treat patients effectively.

PolyBox.app is a marketing tool designed to enhance the reporting processes of marketing agencies and teams through automation and AI technology. The platform enables users to consolidate data from various sources, facilitating real-time queries and analysis. By automating the generation of reports, PolyBox allows marketers to efficiently track campaign performance and optimize strategies, minimizing reliance on traditional spreadsheets and manual reporting methods. The service includes detailed visual dashboards that provide insightful overviews of campaign results, enabling teams to make informed decisions swiftly. Ultimately, PolyBox.app aims to improve the accuracy of reporting and save time for marketing professionals, helping them deliver superior results for their clients.

Microbritt is a developer of advanced micromachining technology specializing in the fabrication of customer-defined products from a wide range of materials. The company utilizes a patented process that enables the defect-free micromachining of brittle materials, applicable at wafer-scale and beyond. This innovative technology facilitates rapid prototyping, significantly enhancing the rate of innovation for its clients.

Dragonfly Insulation is a spin-out from Newcastle University focused on advancing aerogel manufacturing through an innovative and energy-efficient process. The company specializes in producing synthetic nanostructured porous ceramic products that provide exceptional thermal insulation across various industries, including aerospace, defense, marine, oil and gas, and construction. By simplifying the manufacturing process and reducing energy consumption, Dragonfly Insulation aims to deliver a range of aerogel products that enhance fire safety features and improve overall performance in civil applications.

Newcells Biotech Limited is a biotechnology company specializing in the production of induced pluripotent stem cells (iPSCs) and their differentiation into various cell and tissue types for research and development purposes. Founded in 2014 and based in Newcastle upon Tyne, United Kingdom, the company offers a diverse portfolio of off-the-shelf iPSC-derived cell lines, including custom iPSCs generated from patient tissues, neural progenitor cells, cardiomyocytes, and various somatic cell types. Newcells Biotech focuses on providing high-quality cells and development services, including tissue sourcing and bespoke differentiation, to support customers engaged in drug discovery, pre-clinical development, and disease mechanism investigation. The company's platform also aims to create in vitro cell-based assays that closely replicate human physiology, enhancing the prediction of safety, pharmacology, and efficacy in drug testing.

Aelius Biotech specializes in developing advanced models of the mucosal surfaces of the human body, including the gastrointestinal tract and airways. The company is actively working on creating model systems for the eye and cervico-vaginal tract. Aelius Biotech provides a comprehensive range of in vitro and in vivo testing services, including simple lab assays, routine testing, and rheology. Their integrated model gut system allows healthcare industry participants to simulate key processes such as digestion, mucus permeation, and epithelial absorption in one cohesive platform. By conducting human trials and offering detailed insights, Aelius Biotech aids healthcare companies in making informed, data-driven decisions to enhance and de-risk the development of orally delivered products.

Luminous Group Limited is a specialist in 3D digital technology solutions, offering a range of services tailored to the construction, architecture, and engineering sectors. Founded in 1988 and based in Newcastle upon Tyne, the company provides digital surveying services such as 3D laser scanning, measured building surveys, and point cloud processing. Additionally, Luminous Group excels in digital architecture, offering building information modeling (BIM) consultancy and 3D modeling services. It also develops virtual reality solutions, including real-time interactive visualizations and mixed reality experiences. With over 25 years of experience, Luminous Group has established a strong presence in various industries, including heritage tourism, by delivering innovative and effective digital solutions. The company was previously known as Digital Surveys Limited before rebranding in April 2016.

Manus Neurodynamica Ltd is a company based in North Shields, United Kingdom, established in 2008. It specializes in the development of medical diagnostic technologies aimed at identifying and monitoring neuromotor impairments, particularly focusing on Parkinson’s disease. The company’s innovative device serves as a triage tool that facilitates early diagnosis by analyzing minute limb and hand movements to quantify fine motor skills. This technology, coupled with advanced analytical software, enables clinicians to effectively assess patient movement parameters, thereby enhancing the accuracy of diagnoses and improving the efficiency of neuromotor services. Manus Neurodynamica's solutions are utilized in various settings, including academic research and pharmaceutical studies, as well as in non-medical applications.

NunaBio is a privately-owned specialist DNA development company based in England, United Kingdom. The company focuses on chemical and biological technologies, providing a diverse array of products and services, including long and short deoxyribonucleic acid products available in various scales, from microgram to gram. NunaBio is involved in contract research and development, as well as manufacturing, offering capabilities in cell therapies, vaccines, diagnostics, gene therapies, and advanced DNA biosensing. By delivering these innovative solutions, NunaBio aims to support healthcare professionals in their efforts to treat patients effectively.

Nanovery Limited, based in London, United Kingdom, specializes in the development of nanorobots aimed at detecting cancer mutations. Incorporated in 2018, the company leverages advances in nanotechnology, medicinal chemistry, and artificial intelligence to create a platform that enables rapid and sensitive identification of challenging disease biomarkers. These nanorobots are designed to be introduced into blood samples, where they capture circulating tumor DNA and emit a fluorescent signal, facilitating point-of-care detection. This innovative approach not only aids in the early detection of cancer but also enhances the ability to predict the evolution of cancer cells, significantly improving the chances of patient survival. Supported by academic experts, clinicians, and industry leaders, Nanovery is committed to making cancer detection more efficient and accessible.

MySalesCoach is a technology company that provides a digital platform for sales coaching. Despite the proven impact of coaching on sales representative development and success, managers often lack sufficient time to effectively coach their teams. MySalesCoach addresses this challenge by connecting sales coaches with teams in need of instruction, offering services to support both individuals and groups. The platform enables time-strapped sales managers to provide technological assistance, fostering growth and maximizing sales outcomes for their teams.

Footy.com is an online sportswear platform that specializes in providing a comprehensive price comparison service for football-related products. Catering to customers in the UK, Europe, and the USA, the platform enables users to compare prices on a wide range of items, including football kits, boots, trainers, and training wear from various well-known sporting brands and retailers. By offering access to thousands of products, Footy.com aims to make football merchandise more affordable and accessible for all consumers, facilitating an efficient online shopping experience.

Magnitude Biosciences Limited is a biotechnology company specializing in drug discovery solutions and services, particularly in the field of aging research. Founded in 2018 and based in Durham, United Kingdom, the company utilizes the nematode C. elegans in its research methodologies. Magnitude Biosciences has developed a healthspan machine that employs multiple small computers connected to cameras to monitor these organisms under various experimental conditions. This innovative approach assists academic researchers and the aging research industry in evaluating compounds, including food additives and pharmaceuticals. By providing tailored studies and tools, Magnitude Biosciences aims to enhance the quality of data generated in research areas such as neurodegeneration, toxicity, and microbiome studies, ultimately optimizing productivity for its clients in the drug discovery sector.

Newcells Biotech Limited is a biotechnology company specializing in the production of induced pluripotent stem cells (iPSCs) and their differentiation into various cell and tissue types for research and development purposes. Founded in 2014 and based in Newcastle upon Tyne, United Kingdom, the company offers a diverse portfolio of off-the-shelf iPSC-derived cell lines, including custom iPSCs generated from patient tissues, neural progenitor cells, cardiomyocytes, and various somatic cell types. Newcells Biotech focuses on providing high-quality cells and development services, including tissue sourcing and bespoke differentiation, to support customers engaged in drug discovery, pre-clinical development, and disease mechanism investigation. The company's platform also aims to create in vitro cell-based assays that closely replicate human physiology, enhancing the prediction of safety, pharmacology, and efficacy in drug testing.

CellRev is a biotechnology company that specializes in advancing cell manufacturing processes through innovative bioprocessing technology. The company focuses on enabling the transition from traditional batch processing to continuous processing for adherent cells, which enhances yield and reduces both operating costs and capital expenditure. By addressing critical challenges such as aggregation, clumping, and cell detachment, CellRev offers unique solutions for developers in the fields of cultured meat, cell therapy, and biologics. Its proprietary cell detachment process, combined with a specially designed bioprocess, positions CellRev as a leader in improving the efficiency of manufacturing processes for cell-based vaccines, therapies, and drugs. This disruptive approach aims to eliminate the need for serum in production, thereby streamlining operations for clients in the biomanufacturing landscape.

Hicomply is a software platform that specializes in developing information security management systems (ISMS) to safeguard business data and ensure compliance with various regulations and industry standards. The platform offers a comprehensive and customizable interface that enables users to manage different aspects of information security in a centralized manner. It provides actionable insights through a rich library of structured controls and risk information, allowing businesses of all sizes to effectively implement and maintain their information security management practices. By mapping relevant regulations and legislation, Hicomply empowers organizations to streamline their compliance efforts and enhance their overall security posture.

Manus Neurodynamica Ltd is a company based in North Shields, United Kingdom, established in 2008. It specializes in the development of medical diagnostic technologies aimed at identifying and monitoring neuromotor impairments, particularly focusing on Parkinson’s disease. The company’s innovative device serves as a triage tool that facilitates early diagnosis by analyzing minute limb and hand movements to quantify fine motor skills. This technology, coupled with advanced analytical software, enables clinicians to effectively assess patient movement parameters, thereby enhancing the accuracy of diagnoses and improving the efficiency of neuromotor services. Manus Neurodynamica's solutions are utilized in various settings, including academic research and pharmaceutical studies, as well as in non-medical applications.

BelleVie is a provider of personal care services designed to support individuals in their daily lives while allowing them to maintain their independence. The company offers a range of services, including personal care, meal preparation, home assistance, social engagement, and specialized care. Its operating model is inspired by the Buurtzorg approach, emphasizing self-managing teams that foster meaningful relationships within the care ecosystem. BelleVie aims to create a society where every individual is valued and supported, promoting fulfilling careers within the care sector. To enhance its operations, the company utilizes a custom Wellbeing OS technology platform, which is underpinned by a subscription-based funding model.

Incuto Limited, established in 2016 and headquartered in Ilkley, UK, is a financial technology company specialising in SaaS-based banking software for credit unions, community banks, and CDFIs. The company's flagship product, incuto Hive, is a comprehensive platform supporting back-office processes, financial education, communication, performance management, and service provision for these institutions. Notably, the platform enables credit unions to offer digital banking services, including on-balance-sheet debit cards and sort codes, allowing them to compete with traditional banks and high-cost lenders while serving rural communities and those without physical bank access.

Magnitude Biosciences Limited is a biotechnology company specializing in drug discovery solutions and services, particularly in the field of aging research. Founded in 2018 and based in Durham, United Kingdom, the company utilizes the nematode C. elegans in its research methodologies. Magnitude Biosciences has developed a healthspan machine that employs multiple small computers connected to cameras to monitor these organisms under various experimental conditions. This innovative approach assists academic researchers and the aging research industry in evaluating compounds, including food additives and pharmaceuticals. By providing tailored studies and tools, Magnitude Biosciences aims to enhance the quality of data generated in research areas such as neurodegeneration, toxicity, and microbiome studies, ultimately optimizing productivity for its clients in the drug discovery sector.