National Science Foundation

The National Science Foundation is an independent federal agency in the United States that funds and supports research and education in science and engineering. It funds fundamental research and education across all fields of science and engineering and administers non-dilutive funding programs to aid early‑stage technology development, helping translate discoveries into commercially viable products and services. Through grants and fellowships, the NSF supports researchers, educators, and startups, contributing to innovation and U.S. competitiveness. The agency operates with a substantial budget to advance science, engineering, and STEM education nationwide.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in Wellness

CenSyn

Grant in 2023
CenSyn develops a portable brain health assessment platform. It comprises a handheld EEG device for rapid neurological evaluation, a mobile app for real-time data viewing, and machine learning algorithms to detect mental status changes. This enables medical professionals to conduct cognitive assessments across various settings.

OneSeventeen Media

Grant in 2022
Founded in 2008 and based in Austin, Texas, OneSeventeen Media develops digital tools promoting children's mental well-being. Its flagship product, MyMobileMentor, empowers kids to manage life challenges through skill-building. The company also offers an integrated behavior management system for schools.

KILELE Health Association

Grant in 2022
KILELE Health Association organises weekly outdoor hikes and physical endurance activities tailored to the fitness levels of the participants. They offer physical fitness for resilience, mental wellness coaching, advocacy through experience, and social entrepreneurship.

ControlPoint

Grant in 2022
ControlPoint is an animal diagnostics company dedicated to enhancing animal health and wellness worldwide. The company specializes in developing rapid testing methods for multiple pathogens, particularly in relation to canine respiratory diseases such as kennel cough. By providing veterinarians with fast and accurate test results, ControlPoint enables pet owners to make informed decisions about their pets' health, ultimately improving the quality of care and the everyday lives of animals.

Rift Valley

Grant in 2022
Rift Valley provides solutions for addressing burnout, turnover, and mental health disruption within the workplace. They provide management with a holistic dashboard and suite of tools. They are changing that model and offering institutions the means to prioritize their people effectively.

HeyKiddo

Grant in 2021
HeyKiddo offers tech-based tools for parenting adults and educators to support children's mental, social, and emotional health. Their products include the HeyKiddo™ App, which helps parents anticipate, detect, address, and prevent such struggles in their children, and HeyKiddo™ Huddle, a comprehensive social-emotional learning curriculum designed for educators and homeschooling parents.

Innsightful

Grant in 2021
Innsightful develops wearable devices that monitor and detect anxiety and stress symptoms using AI and machine learning. Their solution integrates biometrics for early detection and provides access to therapists for personalized recommendations, empowering users to understand and manage their mental health.

Notus Labs

Grant in 2021
Notus Labs develops wearable devices that enable remote and non-invasive monitoring of health and performance. Their technology provides users, including both individuals and healthcare professionals, with a comprehensive and continuous overview of vital signs. This information is crucial for optimizing triaging in situations of sudden physiological deterioration. The devices aim to reduce the risk of overexertion injuries and heat-related illnesses, facilitating safer physical activity. Additionally, the products offer training suggestions to help users maximize their physical performance growth while ensuring their well-being.

Cogwear

Grant in 2021
Cogwear is a brain technology company focused on assisting individuals who experience anxiety and depression. The company is developing an advanced wearable device that transcends existing products by integrating cognitive and emotional insights with physical measurements. This innovation aims to enhance human health, safety, and performance. Cogwear utilizes AI-powered algorithms to provide users with real-time access to clinical-grade cognitive and emotional data in various environments. Its wearables are equipped with mobile electroencephalogram (EEG) sensors and machine learning technology, allowing for the accurate measurement and interpretation of brainwave activity. The proprietary dry EEG sensors are designed for comfort and precision, enabling users to track their brain activity through a secure application and shareable dashboard.

Immersive Reality Group

Grant in 2021
Immersive Reality Group, founded in 2004 and headquartered in Bozeman, Montana, specializes in artificial intelligence and virtual reality technology to deliver personalized healthcare solutions. The company operates a platform designed for stress and anxiety management, which utilizes predictive analytics for health monitoring in home environments. By offering tailored virtual reality experiences, Immersive Reality Group aims to help users alleviate symptoms of stress and anxiety in real time, while also providing educational tools to teach effective coping strategies.

Grapevine Health

Grant in 2021
Grapevine Health is a data-driven health media company focused on delivering health information to underserved communities. By utilizing technical expertise and trusted messengers, the company aims to democratize health information and empower patients through empathetic storytelling. Grapevine Health also offers health literacy services that assist health systems, insurers, and medical providers in enhancing community outreach and engagement. Their strategies include designing and delivering culturally appropriate communications and marketing materials, enabling clients to provide health information that is relatable and easily understandable. Through these efforts, Grapevine Health seeks to promote health literacy and sustain healthy behaviors within the communities it serves.

Seaspire Skincare

Grant in 2021
Seaspire Skincare specializes in developing multifunctional colorants and actives inspired by ocean biodiversity. Its flagship product, Xanthochrome, offers broader UV protection and aims to replace harmful ingredients in skincare products, promoting sustainability and reduced adverse effects on human and marine health.

Rarebird

Grant in 2021
Rarebird is a coffee company that specializes in producing coffee products designed to enhance mental wellness. Utilizing Arabica coffee beans, the company incorporates bioactive ingredients, specifically a caffeine replacement compound called paraxanthine, which is backed by research to improve alertness while minimizing jitteriness and anxiety. Rarebird places a strong emphasis on ethical and sustainable sourcing by partnering with third-party coffee suppliers, ensuring that their beans are procured responsibly. This approach not only prioritizes the well-being of consumers but also adds value for coffee producers.

BiomeSense

Grant in 2021
BiomeSense develops an integrated hardware, software, and data platform to scale microbiome data collection and analysis for clinical research. The company integrates at-home monitoring of the gut microbiome through its GutLab smart-bathroom system with the MetaBiome time-series analytics platform to connect microbiome changes with clinical outcomes in real time. Its platform supports large-scale, densely longitudinal datasets to discover, validate, and commercialize microbiome biomarkers, enabling clinicians to apply microbiome insights to improve human health. Founded in 2018 and based in Chicago, BiomeSense seeks to advance precision medicine by providing end-to-end microbiome measurement and analytics.

Lasarrus

Grant in 2020
Lasarrus is a medical device company founded in 2013 and headquartered in Baltimore, Maryland. The company specializes in developing wearable devices aimed at enhancing the physical therapy experience for patients, particularly those with chronic obstructive pulmonary disease. Lasarrus's innovative device facilitates remote monitoring and telemedicine by capturing physiological and range-of-motion data from various points on the body. This technology provides patients with an affordable, comfortable, and non-invasive means to track their health routines and accelerate their recovery process.

Circadian Positioning Systems

Grant in 2020
Circadian Positioning Systems specializes in circadian-targeted technology aimed at optimizing performance in high-stakes environments. The company develops innovative solutions that incorporate wearable sensors and circadian-based light interventions. These technologies are designed to influence and enhance the body’s circadian rhythms, promoting peak physical and mental performance during work hours while improving sleep quality during designated rest periods. By focusing on the synchronization of biological processes, Circadian Positioning Systems aims to help users mitigate fatigue and maintain productivity in mission-critical scenarios.

FruitVaccine

Grant in 2020
FruitVaccine is a company based in Champaign, Illinois, that specializes in the production of fruit-based vaccines aimed at providing immunity against widespread infectious diseases. Founded in 2017, the company focuses on developing noninvasive, orally administered vaccine alternatives. Its products come in various forms, including gummy-like pills, oral drops, and fruit purees, making them accessible and appealing. These vaccines are designed to be natural, vegan-friendly, and environmentally sustainable, distinguishing them from traditional injectable options. FruitVaccine's innovative approach aims to enhance immunization efforts by offering a more palatable and less invasive means of disease prevention.

HabitAware

Grant in 2020
HabitAware, Inc. is a Minneapolis-based company that develops wearable devices aimed at helping individuals manage compulsive behaviors such as hair pulling, nail biting, skin picking, and thumb sucking. The company's flagship product, Liv, is a smart awareness bracelet that utilizes motion sensors to detect these subconscious actions. It connects to a mobile application that provides users with training to recognize and track their behaviors, identify triggers, and implement healthier coping strategies. Founded in 2014, HabitAware combines technology with behavioral science to empower users, particularly those affected by trichotillomania, to gain awareness and control over their habits. The products are available for purchase online.

Behaivior

Grant in 2020
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

Manus Robotics

Grant in 2020
Manus Robotics is a developer of advanced health and wellness devices aimed at promoting independent and healthy living. The company specializes in a wearable robot that offers intelligent daily living assistance to individuals with disabilities. In addition to facilitating daily activities, this device collects and analyzes muscle data from patients, which is crucial for rehabilitation. By focusing on these innovative solutions, Manus Robotics helps individuals with disabilities improve their quality of life and regain their independence.

HumanGo Training

Grant in 2020
HumanGo Training is an imagined solution that understands an athlete’s life beyond their training that knows how many last-minute, unexpected work, family, and friends things can come up in a week.

Viora Health

Grant in 2020
Viora Health is a health and wellness company focused on advancing health equity among diverse populations. It develops tech-enabled, human-centered programs that utilize social and behavioral engagement to enhance the capacity, satisfaction, outcomes, and revenue for healthcare providers. Viora Health's offerings are designed to improve adherence to diabetes prevention and support patients through online tools that track data and report progress to diabetes prevention programs, facilitating compliance with insurance requirements. Funded by reputable organizations such as the American Heart Association, the National Institutes of Health, Johnson and Johnson, and the National Science Foundation, Viora Health's initiatives have shown significant success, achieving a 75% satisfaction score and double retention rates, while also leading to improved patient outcomes such as reduced stress, increased social support, and better access to food.

Prenovo

Grant in 2020
Prenovo is a healthcare services provider that specializes in personalized care. It combines clinical research, proven medical applications, and technology to engage and empower patients, as well as their care teams, throughout the surgical journey, from consultation to recovery. The company's platform focuses on patient engagement in activities like exercise, breathing, and nutrition to enhance surgical outcomes.

HabitAware

Grant in 2019
HabitAware, Inc. is a Minneapolis-based company that develops wearable devices aimed at helping individuals manage compulsive behaviors such as hair pulling, nail biting, skin picking, and thumb sucking. The company's flagship product, Liv, is a smart awareness bracelet that utilizes motion sensors to detect these subconscious actions. It connects to a mobile application that provides users with training to recognize and track their behaviors, identify triggers, and implement healthier coping strategies. Founded in 2014, HabitAware combines technology with behavioral science to empower users, particularly those affected by trichotillomania, to gain awareness and control over their habits. The products are available for purchase online.

Lasarrus

Grant in 2019
Lasarrus is a medical device company founded in 2013 and headquartered in Baltimore, Maryland. The company specializes in developing wearable devices aimed at enhancing the physical therapy experience for patients, particularly those with chronic obstructive pulmonary disease. Lasarrus's innovative device facilitates remote monitoring and telemedicine by capturing physiological and range-of-motion data from various points on the body. This technology provides patients with an affordable, comfortable, and non-invasive means to track their health routines and accelerate their recovery process.

Neuro Rehab VR

Grant in 2019
Neuro Rehab VR is a health tech company developing virtual reality-based neurological rehabilitation and physical therapy systems that combine spatial computing with artificial intelligence to create engaging therapy exercises. Designed with input from physical therapists and powered by machine learning, the platforms tailor each exercise to a patient's specific needs, enabling hospitals, physical therapy centers, and neurological rehabilitation facilities to deliver personalized, efficient care and potentially speed recovery.

Behaivior

Grant in 2018
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

SageSurfer

Grant in 2017
SageSurfer operates a mental healthcare platform designed to empower individuals in overcoming behavioral health challenges by fostering collaboration among their caregivers. The platform facilitates comprehensive, coordinated, and outcome-driven personalized care for mental health and addiction treatment. It enables consumers to actively participate in their care planning, ensuring they have a stronger voice in their treatment process. By centering the consumer in the recovery plan and providing access to their entire care team, SageSurfer aims to create a supportive healthcare environment where individuals are not alone in their journey towards recovery and can easily access help when needed.

DFusion

Grant in 2017
DFusion is a science-based behavioral health research and development company focused on promoting behavior change to improve health outcomes. The company utilizes evidence-based behavior change models and learning theories to create innovative technology solutions aimed at health, prevention, and adherence. DFusion develops smartphone, tablet, and web applications that enhance user experience while facilitating healthier behaviors. Its team comprises scientists and innovators dedicated to challenging conventional approaches and making a positive impact on health and well-being across various life stages. Based in Scotts Valley and Oakland, California, DFusion also offers consultation services and professional development opportunities in health and education, including the development, testing, evaluation, and dissemination of systems that support the adoption of healthy behaviors.

VoluMetrix

Grant in 2015
VoluMetrix develops non-invasive monitoring technologies that capture the venous waveform with a sensor reflecting multiple physiologic conditions, enabling clinicians to assess congestion accurately in home, clinic, or hospital settings. The company aims to enhance well-being by providing reliable vital monitoring and partners with patients and practitioners to guide the practical adoption and implementation of its technology across care pathways.

WiseWear

Grant in 2015
WiseWear is an innovative Internet of Things (IoT) company that specializes in designing and developing connected devices aimed at enhancing health, safety, and security for families. The company focuses on integrating advanced biosensing and wireless communication technologies into everyday items, making technology unobtrusive. WiseWear's product offerings include connected sensing devices that empower users to manage their health and wellness proactively. These devices monitor human activities, provide notifications to emergency contacts during critical situations, and deliver mobile alerts for important communications. By combining style and technology, WiseWear creates products that not only serve practical purposes but also fit seamlessly into daily life.

Awarables

Grant in 2015
Awarables Inc. develops innovative hardware and software solutions focused on sleep monitoring and improvement. Founded in 2013 and based in Baltimore, Maryland, the company offers a multi-sensor wearable device that collects physiological data, including heart rate, along with sleep environment information and patterns. Its mobile application captures user sleep habits, daytime performance, and mood while providing personalized therapy to enhance sleep health. Awarables' sleep analytic system integrates signals from microsensors with proprietary processing algorithms to deliver accurate assessments of sleep quantity and quality. This technology aims to assist both clinicians and consumers by offering real-time feedback to promote better behavioral outcomes related to sleep disorders and overall sleep quality.

Awarables

Grant in 2014
Awarables Inc. develops innovative hardware and software solutions focused on sleep monitoring and improvement. Founded in 2013 and based in Baltimore, Maryland, the company offers a multi-sensor wearable device that collects physiological data, including heart rate, along with sleep environment information and patterns. Its mobile application captures user sleep habits, daytime performance, and mood while providing personalized therapy to enhance sleep health. Awarables' sleep analytic system integrates signals from microsensors with proprietary processing algorithms to deliver accurate assessments of sleep quantity and quality. This technology aims to assist both clinicians and consumers by offering real-time feedback to promote better behavioral outcomes related to sleep disorders and overall sleep quality.

Gliimpse

Grant in 2013
Gliimpse is a health record management platform focused on empowering individuals to manage their personal health information. The company aims to eliminate the fragmentation of patient data by aggregating various medical records into a coherent, patient-owned longitudinal health profile. This allows users to collect and share their health information securely, providing a comprehensive overview of their medical history. Consumers can seamlessly track records from multiple patient portals while adding their own data, resulting in a personalized summary of their health history accessible at their convenience. Through its innovative approach, Gliimpse addresses the need for better control and visibility over personal health data.

Education Development Center (EDC)

Grant in 2013
Education Development Center (EDC) is a global nonprofit organization focused on designing, delivering, and evaluating innovative programs aimed at tackling critical challenges in education, health, and economic opportunity. By collaborating with public and private partners, EDC seeks to enhance educational outcomes, promote health and wellness, prepare the workforce, and foster civic engagement. Through its comprehensive approach, EDC addresses urgent societal needs by leveraging the strengths of individuals and systems to create sustainable impact in communities worldwide.

ChromaDex

Grant in 2013
ChromaDex is a global nutraceutical company that discovers, acquires, develops, and commercializes patented ingredients for dietary supplements, food, beverage, skin care, and pharmaceutical markets. Its flagship product, Niagen (nicotinamide riboside), enhances NAD levels for healthy aging.

Education Development Center (EDC)

Venture Round in 2010
Education Development Center (EDC) is a global nonprofit organization focused on designing, delivering, and evaluating innovative programs aimed at tackling critical challenges in education, health, and economic opportunity. By collaborating with public and private partners, EDC seeks to enhance educational outcomes, promote health and wellness, prepare the workforce, and foster civic engagement. Through its comprehensive approach, EDC addresses urgent societal needs by leveraging the strengths of individuals and systems to create sustainable impact in communities worldwide.
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