Matrix

Matrix Partners is a venture capital firm established in 1977, with offices in San Francisco, Cambridge, Shanghai, Beijing, Mumbai, and Bangalore. The firm focuses on seed, early-stage, late-stage, and growth capital investments across various sectors, including software, communications, artificial intelligence, fintech, digital health, and clean technology. With a commitment to building long-term relationships with entrepreneurs, Matrix Partners aims to support visionary founders in developing significant, industry-leading companies. The firm has a strong track record, having participated in hundreds of investments, with many of its portfolio companies achieving successful IPOs or profitable mergers and acquisitions. The team at Matrix Partners combines local insights with global expertise, comprising both former entrepreneurs and seasoned investors.

Ben Altshuler

Partner

Tim Barrows

Partner

Diana Kimball Berlin

Partner

Rahul Chaudhary

Venture Partner

Pranay Desai

Managing Director

Phyllis Doherty

Administrative Partner

Paul J. Ferri

Co-Founder

Jacob Jolis

Partner

Patrick Malatack

Partner

Harry Man

Partner

Kojo Osei

Partner

Kun Qian

Managing Director

Brian Ru

Venture Partner

Varun Singhal

Senior Associate

Dana Stalder

General Partner

David Su

Founding Managing Partner

Ilya Sukhar

General Partner

Sun Linghao

Managing Partner

Huadong Wang

Partner

Kevin Xiong

Partner

Michael Zuo

Partner

T.J. Parker

Partner

Past deals in Nanotechnology

Neptune Robotics

Series A in 2022
Neptune Robotics develops and manufactures underwater drones designed for enterprises in the maritime industry. Its underwater drones reduce the spread of invasive species in the ocean and also include filtration and debris collection systems designed to clean up oceans, enabling the reduction of waste in the oceans and improve ocean ecosystems.

Onechip Bioelectronics

Series B in 2022
Zhangjiagang Onechip Bio-Technology Co.,Ltd. develops and manufactures new generations of biochemical sensor chips and nanomaterials for various applications. It offers pH chip, such as nano-electrodes; biochips; and nanometer materials, including oil absorption and sustained release products and battery protection products. The company’s products are based on the nanoscale electronic biochemical sensors and nanomaterial technologies. It sells its products online. Zhangjiagang Onechip Bio-Technology Co.,Ltd. was founded in 2014 and is based in Zhangjiagang, China.

Protoga

Seed Round in 2021
Yuan Yu Bio is a biotech firm that focused on the development of innovative microalgae biosynthesis technology.

Radium Technology

Series A in 2021
Radium Technology focuses on deep application of metal 3D printing technology in the field of mold manufacturing and application.

KYinno

Series A in 2021
Kyinno Biotechnology Co., Ltd. develops anti-tumor drugs and offers customized product development for immuno-oncology and kinase inhibitor discovery. It offers engineered cell lines and antibody products. The company offers services platforms, such as engineered custom cell line development, cell-based assay validation and compound screening, phage display library and hybridoma technology for antibody drug discovery, and cancer cell panel compound profiling and biomarker discovery. Kyinno Biotechnology Co., Ltd. was founded in 2017 and is based in Beijing, China.

NeuraMatrix

Series A in 2021
NeuraMatrix is ​​a cutting-edge brain-computer interface technology developer. It uses cutting-edge question-computer interface technology to establish the ultimate way and platform for interactive human-computer information interaction, and realizes a one-stop service solution from hardware to software to digital devices. Influencing factors in brain science, neurological disease research, diagnosis and treatment, and innovating the new drug research and development evaluation system for neurological diseases, the wellhead is leveraging the enormous commercial application value of brain-computer interfaces. Recently completed 100 million yuan A round of financing, led by Huagai Capital, Saudi Aramco's diversified venture capital fund Prosperity7 Ventures, and old shareholder Jingwei China joined the investment. This round of financing will be mainly used for R&D equipment update, chip mass production, product iteration and market promotion.

INMO Glass

Seed Round in 2021
INMO Glass are Foldable, monocular Augmented Reality (AR) glasses.

Zhongke Guosheng

Angel Round in 2021
Zhongke Guosheng is a bio-based materials R&D firm that designs and develops furan-based bio-based materials.

LightForce

Series C in 2021
LightForce Orthodontics addresses this problem by applying patented, next-generation manufacturing technology adapted for use in orthodontic treatment by the industry's leading experts. It enables orthodontists to utilize its 3D-printing technology to create custom braces for each individual patient, significantly reducing the number of adjustment visits needed.

Joes Future Food

Series A in 2021
Developer of artificial meat. The company develops artificial meat and cultured alternative protein products at the cellular level, committing to creating a new solution for future food supply.

SemiDrive

Series B in 2021
Nanjing SemiDrive Technology Ltd. is a semiconductor company based in Nanjing, China, established in 2018. The firm specializes in designing and manufacturing core processor chips for the automotive industry, focusing on applications such as advanced driver assistance systems (ADAS) and autonomous driving. Its product lineup includes the X9 chip for high-performance eCockpit applications, the V9 chip for ADAS and autonomous driving, and the G9 chip, which serves as a vehicle central gateway connecting multiple domains. SemiDrive also offers research and development services for intelligent core processors and provides system-level turnkey solutions. The company operates with a fabless manufacturing model, with additional R&D facilities in Beijing and an office in Shenzhen, addressing the growing demand for smart driving technologies and high-performance industrial microprocessors in the automotive sector.

NiKang Therapeutics

Series C in 2021
NiKang Therapeutics, Inc. is a biotechnology company established in 2017 and located in Wilmington, Delaware. The company is dedicated to discovering and developing innovative small molecule oncology medicines aimed at addressing unmet medical needs in cancer treatment. By employing a discovery approach that leverages target structure biology and structure-based drug design, NiKang Therapeutics aims to facilitate the rapid and efficient development of proprietary drug candidates with optimal pharmacological properties. The company seeks to enhance the treatment options available to healthcare providers, ultimately improving patient outcomes in the fight against cancer.

X-EPIC

Series A in 2021
X-EPI is a Nanjing city-based startup aimed at building up China’s own EDA (Electronic Design Automation) industrial software technology.

Ronovo Surgical

Series A in 2021
Ronovo Surgical, established in 2019 and based in Shanghai, focuses on advancing minimally invasive surgery (MIS) through the development of a cutting-edge soft tissue surgery robot platform. Founded by experienced professionals from leading companies in surgical and industrial robotics, Ronovo aims to transform surgical practices in China by utilizing advanced robotics and digital solutions. The company's innovative platform is designed to enhance surgical efficiency and precision across various specialties, ultimately improving patient outcomes and healthcare economics. Through robust research and development capabilities and strategic global partnerships, Ronovo is committed to disrupting traditional surgical care and providing intelligent solutions for the medical industry.

QnQuality Pharmaceuticals

Series A in 2021
QnQuality Pharmaceuticals is a new drug research and development specialist for cancer-assisted therapeutics, focusing on unmet clinical needs in the field of oncology supportive care, and is committed to helping cancer patients around the world improve their quality of life. Kuankuo Pharmaceutical has established a rich R&D pipeline covering six indications and a research and development team in China and the United States (

NeuraMatrix

Seed Round in 2021
NeuraMatrix is ​​a cutting-edge brain-computer interface technology developer. It uses cutting-edge question-computer interface technology to establish the ultimate way and platform for interactive human-computer information interaction, and realizes a one-stop service solution from hardware to software to digital devices. Influencing factors in brain science, neurological disease research, diagnosis and treatment, and innovating the new drug research and development evaluation system for neurological diseases, the wellhead is leveraging the enormous commercial application value of brain-computer interfaces. Recently completed 100 million yuan A round of financing, led by Huagai Capital, Saudi Aramco's diversified venture capital fund Prosperity7 Ventures, and old shareholder Jingwei China joined the investment. This round of financing will be mainly used for R&D equipment update, chip mass production, product iteration and market promotion.

Senti Bio

Series B in 2021
Senti Biosciences is a clinical-stage biotechnology company based in South San Francisco, California, focused on developing innovative gene and cell therapies using its proprietary synthetic biology platform. Founded in 2016, the company aims to address complex diseases through advanced therapeutic solutions. Senti's technology includes engineered allogeneic chimeric antigen receptor natural killer (CAR-NK) cells, which are designed to target and eliminate cancer cells while minimizing damage to healthy tissue. Among its product candidates are SENTI-202, a Logic Gated CAR-NK cell therapy intended for cancer treatment, and SENTI-301A, which targets hepatocellular carcinoma. Senti Biosciences operates as a resident company at Johnson & Johnson Innovation's JLABS in South San Francisco, collaborating with experts in synthetic biology and computation to advance its therapeutic developments.

Joes Future Food

Angel Round in 2020
Developer of artificial meat. The company develops artificial meat and cultured alternative protein products at the cellular level, committing to creating a new solution for future food supply.

nference

Series C in 2020
nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.

Nuance Biotech

Series D in 2020
NUANCE BIOTECH INC operates as a pharmaceutical development company. The company provides capsules, injections, and tubes. It also engages in research and development for drug development, commercial and academic platform for pharmaceuticals, and contract sales organization services. The company was founded in 2014 and is based in Shanghai, China.

SemiDrive

Series A in 2020
Nanjing SemiDrive Technology Ltd. is a semiconductor company based in Nanjing, China, established in 2018. The firm specializes in designing and manufacturing core processor chips for the automotive industry, focusing on applications such as advanced driver assistance systems (ADAS) and autonomous driving. Its product lineup includes the X9 chip for high-performance eCockpit applications, the V9 chip for ADAS and autonomous driving, and the G9 chip, which serves as a vehicle central gateway connecting multiple domains. SemiDrive also offers research and development services for intelligent core processors and provides system-level turnkey solutions. The company operates with a fabless manufacturing model, with additional R&D facilities in Beijing and an office in Shenzhen, addressing the growing demand for smart driving technologies and high-performance industrial microprocessors in the automotive sector.

NiKang Therapeutics

Series B in 2020
NiKang Therapeutics, Inc. is a biotechnology company established in 2017 and located in Wilmington, Delaware. The company is dedicated to discovering and developing innovative small molecule oncology medicines aimed at addressing unmet medical needs in cancer treatment. By employing a discovery approach that leverages target structure biology and structure-based drug design, NiKang Therapeutics aims to facilitate the rapid and efficient development of proprietary drug candidates with optimal pharmacological properties. The company seeks to enhance the treatment options available to healthcare providers, ultimately improving patient outcomes in the fight against cancer.

LightForce

Series B in 2020
LightForce Orthodontics addresses this problem by applying patented, next-generation manufacturing technology adapted for use in orthodontic treatment by the industry's leading experts. It enables orthodontists to utilize its 3D-printing technology to create custom braces for each individual patient, significantly reducing the number of adjustment visits needed.

nference

Series B in 2020
nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.

EnnovaBio

Series A in 2019
Ennovabio is a Chinese drug developer that focuses on creating drugs targeting brain glioma.

Lansion Biotechnology

Series C in 2019
Lansion Biotechnology is specialized in research & development, production, sell, services of in vitro diagnostic reagents and devices. With its advanced technology concept, Lansionbio provides equioment, reagents and services to world-wild clients according to their needs.

OnQuality Pharmaceuticals

Series A in 2019
OnQuality Pharmaceuticals offers trials to assess the safety and efficacy of a targeted supportive care agent that addresses the specific side effects of vascular endothelial growth factor receptor (VEGFR) inhibitors among cancer patients.

SemiDrive

Seed Round in 2019
Nanjing SemiDrive Technology Ltd. is a semiconductor company based in Nanjing, China, established in 2018. The firm specializes in designing and manufacturing core processor chips for the automotive industry, focusing on applications such as advanced driver assistance systems (ADAS) and autonomous driving. Its product lineup includes the X9 chip for high-performance eCockpit applications, the V9 chip for ADAS and autonomous driving, and the G9 chip, which serves as a vehicle central gateway connecting multiple domains. SemiDrive also offers research and development services for intelligent core processors and provides system-level turnkey solutions. The company operates with a fabless manufacturing model, with additional R&D facilities in Beijing and an office in Shenzhen, addressing the growing demand for smart driving technologies and high-performance industrial microprocessors in the automotive sector.

Sila

Series E in 2019
Sila Nanotechnologies Inc. specializes in developing advanced materials for batteries that enhance energy density. The company serves various sectors, including automotive, consumer electronics, electric utilities, and aerospace, by providing innovative battery materials chemistry. Founded in 2011 and based in Alameda, California, Sila collaborates closely with leading original equipment manufacturers (OEMs) to support their product development timelines and partners with battery manufacturers to facilitate commercial cell production.

Chameleon Biosciences

Seed Round in 2019
Chameleon Biosciences Inc. specializes in developing gene therapy solutions using Adeno Associated Virus (AAV) technology to address rare genetic diseases. Founded in 2017 and based in San Anselmo, California, the company focuses on delivering therapeutic proteins to targeted tissues while minimizing immune responses to enhance gene delivery and reduce immunogenicity. Chameleon aims to transform the treatment landscape for genetic disorders, particularly in infants, where a significant percentage of fatalities are attributed to these conditions. The company is dedicated to ensuring that affected children receive accurate, lower-dose treatments that can be administered multiple times as needed. By masking foreign proteins and shielding the viral capsid from antibodies, Chameleon seeks to increase the range of diseases that can be treated effectively, thereby improving patient outcomes and quality of life.
NASN Automotive Electronics is committed to providing advanced and complete chassis electronic control products, ADAS and autonomous driving related core technologies for the Chinese automotive market. The main products include NBooster intelligent brake system, brushless electric steering EPS controller and wire control system. It is a scientific and technological innovation enterprise integrating R&D, production and sales.

LightForce

Venture Round in 2018
LightForce Orthodontics addresses this problem by applying patented, next-generation manufacturing technology adapted for use in orthodontic treatment by the industry's leading experts. It enables orthodontists to utilize its 3D-printing technology to create custom braces for each individual patient, significantly reducing the number of adjustment visits needed.

Sila

Series D in 2018
Sila Nanotechnologies Inc. specializes in developing advanced materials for batteries that enhance energy density. The company serves various sectors, including automotive, consumer electronics, electric utilities, and aerospace, by providing innovative battery materials chemistry. Founded in 2011 and based in Alameda, California, Sila collaborates closely with leading original equipment manufacturers (OEMs) to support their product development timelines and partners with battery manufacturers to facilitate commercial cell production.

Si'ao Biotechnology

Series A in 2018
Si'ao Biotechnology engages in the development and production of genetic engineering vaccines and test kits.

Adlai Nortye

Series B in 2018
Adlai Nortye Biopharma Co., Ltd. is a biopharmaceutical company based in Hangzhou, China, focused on the research and development of innovative treatments for cancer and metabolic diseases. Founded in 2004 and formerly known as Sinopep Pharmaceutical Inc., the company has shifted its emphasis to oncology and immuno-oncology. Adlai Nortye is committed to improving patient outcomes through the discovery and commercialization of differentiated medicines. With a solid foundation in peptide and protein drug development, the company has broadened its scope to include small molecules and therapeutic antibodies. It holds 23 granted patents and has published 7 PCT applications. Through strategic collaborations with global partners, Adlai Nortye has established a diverse pipeline of programs ranging from early pre-clinical stages to those ready for phase 3 clinical trials.

nference

Series A in 2018
nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.

Nuance Biotech

Series A in 2017
NUANCE BIOTECH INC operates as a pharmaceutical development company. The company provides capsules, injections, and tubes. It also engages in research and development for drug development, commercial and academic platform for pharmaceuticals, and contract sales organization services. The company was founded in 2014 and is based in Shanghai, China.

nference

Seed Round in 2016
nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.

Sila

Series A in 2011
Sila Nanotechnologies Inc. specializes in developing advanced materials for batteries that enhance energy density. The company serves various sectors, including automotive, consumer electronics, electric utilities, and aerospace, by providing innovative battery materials chemistry. Founded in 2011 and based in Alameda, California, Sila collaborates closely with leading original equipment manufacturers (OEMs) to support their product development timelines and partners with battery manufacturers to facilitate commercial cell production.

nkf-pharma

Venture Round in 2011
Nanjing King-friend Biochemical Pharmaceutical is focused on research, production, and sales of raw material medicines of heparin sodium. It mainly produces a series of products including heparin sodium and low molecular heparin. Nanjing King-friend Biochemical Pharmaceutical was restructured and founded in March 2005. As of today, it owns two subsidiaries and two holding subsidiaries and its registered capital is 36 million. Its output of heparin sodium accounts for 20% of the world’s heparin sodium.

NibiruTech Limited

Series A in 2011
NibiruTech, founded in July 2007, is engaged in iOS application development. Its main products include IslandEmpire, GalaxyEmpire, and KingsEmpire. Galaxy Empire ranked first in North America Apple’s AppStore on April 4, 2013, the best a Chinese-developed app has done in the AppStore. NibiruTech applies advanced concepts and technology to the development and has been invited to publish seven articles on Chinese magazines for programmers. InfoQ, a technology media site interviewed NibiruTech, recognizing the latter’s advanced development concepts.

Nala

Series A in 2010
NALA is an online cosmetics retailer founded in May 2009 by Liu Yongming, an overseas returnee. The company has grown to employ over 100 people and operates multiple centers, including management, customer service, warehousing, and logistics. NALA sells cosmetics and beauty tools through its own B2C platform and on Taobao, where it has achieved significant recognition by earning five crowns in one year and a gold crown within 18 months. This success has positioned NALA among the top three cosmetics dealers on Taobao and as the leading domestic dealer of Korean cosmetics in a short span. In 2010, the company formed strategic partnerships with notable enterprises, including Albaba, LG Corporation, ITOCHU Corporation, Shiseido, and Proya, enhancing its market presence and ability to facilitate brand entry into the Chinese market.

Xtalic

Venture Round in 2008
Xtalic Corporation, founded in 2005 and based in Marlborough, Massachusetts, specializes in developing and manufacturing advanced metal coatings for various applications, primarily in the electronics sector. The company offers innovative nanostructured coatings that enhance corrosion and wear resistance while providing exceptional aesthetics. Notable products include XTRONIC, a barrier layer designed to improve durability, and LUNA, which serves as a gold replacement for electrical connectors. Xtalic's electroplating process is environmentally friendly, eliminating the use of hexavalent chromium, thereby reducing compliance costs and safety risks for workers. By enabling clients to decrease reliance on expensive raw materials and replace hazardous substances, Xtalic contributes to more sustainable manufacturing practices in both decorative and functional metal finishing.

Grandis

Venture Round in 2005
Grandis is the pioneer in developing and licensing innovative non-volatile memory solutions derived from cutting-edge research in spintronics. Its mission is to enable revolutionary products through application of the electron's spin to store, manipulate and transmit information.

Nauticus Networks

Series B in 2002
Nauticus Networks, Inc. is a networking company that creates powerful infrastructure products to deliver the next generation Internet. The new generation of application switches enables enterprises and service providers to deliver high performance network and security services.

Nauticus Networks

Series A in 2001
Nauticus Networks, Inc. is a networking company that creates powerful infrastructure products to deliver the next generation Internet. The new generation of application switches enables enterprises and service providers to deliver high performance network and security services.
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