MassChallenge is a global nonprofit startup accelerator headquartered in Boston, Massachusetts, founded in 2009. It supports early-stage entrepreneurs from various industries, including technology, healthcare, and finance, by providing mentorship, resources, and networking opportunities. With locations in countries such as Israel, Mexico, Switzerland, and Texas, MassChallenge operates a non-equity model, allowing startups to retain full ownership while benefiting from expert guidance and connections. The accelerator conducts various programs tailored to specific sectors, such as MassChallenge HealthTech and MassChallenge FinTech, which facilitate partnerships between startups and established enterprises to drive innovation and market growth. Through its extensive global network, MassChallenge aims to strengthen the innovation ecosystem and empower high-potential startups to create meaningful impact.
Sóliome is a Biotechnology company that develops protein-based sunscreens that are safe. The company was founded in 2021 and is based in San Francisco, California.
KerlyGirl
Non Equity Assistance in 2021
KerlyGirl is a B2C startup offering an e-commerce site selling hair masks, curl creams, and serums. Its products are specifically catered to people with Type 3 and 4 hair — the very tightest coils — and are all plant-based and COSMOS-certified organic.
Kura Skin
Non Equity Assistance in 2021
Kura Skin is a skincare matchmaking platform. We use data and our proprietary matchmaking algorithm to help our customers cut through the clutter and find what works for a fraction of the cost and none of the hassle.
Hue
Non Equity Assistance in 2021
Hue Beauty is a beauty technology and sampling platform designed to assist beauty shoppers in identifying makeup products that complement their unique skin tones. The platform integrates with beauty brands' e-commerce websites, utilizing photo technology and a community of beauty advisors to facilitate accurate shade matching. Additionally, Hue Beauty offers customized try-at-home shade sampling kits, enhancing the shopping experience. The company also develops shoppable video technology, allowing online beauty brands to incorporate user-generated videos into their marketing strategies. This approach fosters customer trust and engagement by providing authentic content. Moreover, Hue Beauty employs an artificial intelligence-powered recommendation engine to analyze shoppers' skin tones, types, and beauty preferences, enabling clients to generate genuine reviews in various formats.
React4life
Non Equity Assistance in 2021
React4life is an Italian biotech company established in 2016 by Silvia Scaglione and Maurizio Aiello, following over 15 years of research and development. The company focuses on advancing biomedical research through its innovative technology, MIVO® (Multi In Vitro Organ), which represents a next-generation organ-on-a-chip system. This microphysiological platform allows researchers to simulate human biology more accurately in laboratory settings, addressing the limitations of traditional in vitro assays and animal testing. React4life's technology enhances the reliability and predictivity of various applications, including pharmaceutical drug testing, personalized medicine, immuno-oncology therapies, cosmetics, dermatology, and nutraceuticals. By enabling the cultivation of three-dimensional human-like tissues for in vitro testing, React4life aims to improve the effectiveness of laboratory experiments and promote ethical research practices.
HanaBi
Non Equity Assistance in 2020
HanaBi wants to offer these customers a ready-to-go solution to penetrate the in-wash fabric solid scent booster market, and to their consumers better product to fulfill their long-lasting fragrance expectations.
Mibiomics
Non Equity Assistance in 2020
MIBIOMICS mission is to develop innovative, safe, and effective microbiome-based solutions to treat currently incurable skin diseases.
Renzoe Box
Non Equity Assistance in 2020
Renzoe Box is a beauty platform that combines hardware and software to simplify personal makeup organization. The company offers an innovative makeup storage and pod system designed to accommodate various makeup products within a single, compact box. This system allows users to create their personalized palettes while organizing their makeup accessories in designated compartments. By streamlining the makeup collection process, Renzoe Box enables users to manage and transport their beauty products more efficiently.
Upwell cosmetics
Non Equity Assistance in 2020
Upwell’s is a cosmetic industry provides patented algae wax with safe ingredients.
Mibiomics
Non Equity Assistance in 2020
MIBIOMICS mission is to develop innovative, safe, and effective microbiome-based solutions to treat currently incurable skin diseases.
Abeja Reyna
Grant in 2019
Abeja Reyna specializes in the online production and marketing of honey-based products. The company manufactures natural beauty care items that harness the beneficial properties of honey, known for its moisturizing, antibacterial, and antioxidant qualities. Their products are crafted using honey nutrients and are free of parabens, ensuring a focus on organic and sustainable ingredients. By emphasizing the health benefits of honey, Abeja Reyna aims to provide consumers with effective and environmentally friendly options in personal care.
Belleza check
Non Equity Assistance in 2019
Bellezacheck is the 'Tripadvisor' of beauty product and that provides consumer reviews&ratings on website.
Aisling Organics
Non Equity Assistance in 2019
Aisling Organics is a pioneering company that specializes in high-performance organic makeup and skincare products. Founded by Krysta Lewis, who sought healthier alternatives after discovering that her foundation was detrimental to her health, Aisling aims to bridge the gap between beauty and wellness. The company offers a diverse range of products, including concealer, liquid foundation, eyeshadow, lip gloss, and mascara, all formulated from crushed plants and herbs. Aisling's e-commerce platform allows consumers to access skin-friendly alternatives to conventional cosmetics, ensuring that individuals do not have to compromise their health for beauty.
ZeoVation
Non Equity Assistance in 2019
ZeoVation Inc., founded in 2016 and located in Columbus, Ohio, specializes in the production of nanozeolites and hierarchical zeolites. These advanced materials are designed to enhance a variety of consumer products, including skin care lotions, sunscreens, and laundry detergents, by improving the efficiency of water softeners and filtration systems. ZeoVation also supplies zeolite materials to various markets such as sun and skin care, home care, healthcare, coatings, and water and gas purification. The company focuses on developing innovative solutions, including a controlled-release antimicrobial and antiviral particle that can be integrated into various applications like sprays, coatings, and textiles. This technology aims to combat the spread of antibiotic-resistant bacteria and viruses, including SARS-CoV-2, thereby contributing to safer and cleaner products.
Impact Everything
Non Equity Assistance in 2019
Impact Everything is a business focused on community assistance through the sale of various products, including clothing, accessories, home goods, and bath and body products. The company operates an online platform that allows customers to select from a diverse range of items while also contributing to solutions for pressing global issues with each purchase. Impact Everything emphasizes the importance of social responsibility, enabling consumers to make a positive impact through their buying choices. The company provides multiple contact options, including mail, phone, and a physical address, to facilitate communication with its community.
SoaPen
Non Equity Assistance in 2018
Soapen is a cosmetics company founded in 2016 by Amanat Anand and Shubham Issar, specializing in handmade soap designed for children. The company produces roll-on soap bottles that aim to promote hygiene habits in a playful manner. These innovative bottles contain non-irritating, non-toxic soap that is free from harmful substances such as SLS, parabens, phthalates, and any animal by-products. By providing a fun and engaging way for kids to wash their hands, Soapen encourages healthy hygiene practices among its young users.
KUSHAE
Non Equity Assistance in 2018
KUSHAE offers feminine personal care items. They provide a wide range of goods, including spray, body wash, lotions, and more. They also provide free shipping on orders of $60 or more.
Canomiks
Non Equity Assistance in 2018
Canomiks operates a genomics and artificial intelligence-based technology platform that focuses on testing and certifying the biological efficacy and safety of ingredients and formulations. Its services cater to the functional food and beverage, dietary supplement, and skincare industries, allowing companies to develop safe and effective products efficiently. By leveraging omics science, data analytics, machine learning, and bioinformatics, Canomiks streamlines the validation process for product efficacy, ultimately enabling clients to enhance product quality while reducing development time and costs. The company's long-term vision is to actualize the concept of food as medicine.
Orchid Green
Grant in 2017
Orchid Green has developed the natural compound AAPE1, which is an anti-aging antioxidant for skin. AAPE1 is chemically stable, resistant under high and low temperatures, and keeps its effectiveness over time. AAPE is water soluble and inhibits wrinkle formation.
Kreyol
Grant in 2017
Kreyol Essence is an agribusiness focused on providing affordable luxury beauty products sourced from Haiti. It serves as a leading platform for organic commodities from the region, offering a range of signature products that emphasize natural ingredients and social impact. The company is dedicated to empowering women by employing 400 local women and farmers, thus contributing to improvements in environmental, agricultural, and economic conditions in Haiti. Kreyol Essence operates with a mission to address complex social issues through its business model, promoting sustainability and community welfare.
Droplette
Grant in 2017
Droplette Inc., founded in 2017 and based in Boston, Massachusetts, specializes in the development of a needle-free skincare device that utilizes a patent-pending transdermal delivery system. This innovative technology allows for the delivery of drugs up to 60% larger than traditional treatments, penetrating deeply into the skin over large surface areas. The device is designed to be painless, contact-free, and portable, generating no disposables. Initially aimed at delivering antibiotics for serious skin conditions such as ulcers and infections, Droplette also envisions future applications for localized delivery of chemotherapeutics for skin cancer and anti-aging treatments. By enabling effective skincare without harmful chemicals, Droplette aims to transform skin health through scientific advancement.
BeautyLynk
Grant in 2016
BeautyLynk, Inc. is a beauty booking platform that offers on-location and web-based services, allowing users to schedule hair and makeup appointments at their homes, offices, hotels, and other locations. Founded in 2015 and headquartered in Boston, Massachusetts, the company primarily caters to women but also provides services for men and children aged 17 and older. BeautyLynk operates in major cities, including Atlanta, Boston, and Washington, D.C. The platform enables users to access professional hair stylists and makeup artists conveniently, addressing their grooming needs while saving time and money.
MesenFlow Technologies
Grant in 2016
MesenFlow Technologies specializes in bio-imaging technology aimed at enhancing drug and cosmetic development. The company has created a platform that accelerates the drug development process by addressing challenges related to species cross-reactivity, animal testing, and understanding human diseases. Utilizing proprietary protocols on primary human cells, MesenFlow enables early definition of a drug's mechanism of action and translational relevance. The technology has also been adapted for the cosmetics and nutrition sectors, allowing for the assessment of the physiological impact of cosmetic or nutraceutical candidates during the early development phase. This approach supports environments where animal-free testing is essential and emphasizes the importance of understanding human biology in product development.
MoringaConnect
Grant in 2014
They are changing the story of the smallholder farmer starting with Moringa, known worldwide as “the miracle tree” for its highly nutritional leaves. They take the forgotten part --the seeds-- and process them into an oil with unmatched cosmetic benefits for hair and skin care and a press meal for animal feed and water purification. They manage the entire supply chain- training, micro-credit, miniaturized value-added processing, and marketing to a global audience.
Droplette
Non Equity Assistance in 2014
Droplette Inc., founded in 2017 and based in Boston, Massachusetts, specializes in the development of a needle-free skincare device that utilizes a patent-pending transdermal delivery system. This innovative technology allows for the delivery of drugs up to 60% larger than traditional treatments, penetrating deeply into the skin over large surface areas. The device is designed to be painless, contact-free, and portable, generating no disposables. Initially aimed at delivering antibiotics for serious skin conditions such as ulcers and infections, Droplette also envisions future applications for localized delivery of chemotherapeutics for skin cancer and anti-aging treatments. By enabling effective skincare without harmful chemicals, Droplette aims to transform skin health through scientific advancement.
EyeDoll Chatter
Grant in 2013
Eyedoll Chatter is an application that offers scented eyeshadows, face shimmers, and lip glosses.
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