MassChallenge

Speratum is a biopharmaceutical company focused on microRNA-directed oncology therapies. The Company was founded in 2014 by Christian Marín-Müller, Ph.D. and is dedicated to the development of a patented treatment for pancreatic cancer based on the combination of tumor suppressive microRNA molecules and nanoparticle-based drug delivery technologies. The Company is currently entering the final stage of preclinical trials for the pancreatic cancer therapy, while simultaneously expanding the patent’s coverage to incorporate other types of cancer and non-cancer indications and illnesses and expanding its intellectual property (IP) portfolio with complementary technologies in the fields of nanotechnology, medical devices and veterinary medicine.

Freshean is a nanotechnology firm dedicated to advancing clean air innovation through the application of deep scientific principles. The company specializes in nanoengineering design and nanofabrication techniques that effectively eliminate harmful chemical substances and odors from indoor air environments. By leveraging these advanced technologies, Freshean aims to create a pollutant-free and carbon-neutral future, providing businesses with solutions to maintain clean and fresh indoor atmospheres.

OSEM provides best-in-class solutions to nanodrugs manufacturing that revolutionize healthcare, to revolutionize drug delivery systems and contribute to the advancement of life-saving therapeutics.

We founded AtomicAI to bring advances in computing and machine learning to nanomaterials manufacturing. We believe that nanomaterials will transform energy, electronics, and quantum technologies. But nanomaterials are really hard to make. We're here to help.

MIPRONS is on a mission to develop a space propulsion system for nanosatellites.

Intelligent NanoFiber, Inc. is a company that specializes in the design and manufacturing of advanced NanoFiber, an absorbent nano-material with the capability to capture and neutralize toxins and infectious diseases. Founded in 2020 and headquartered in College Station, Texas, the company’s innovative material, composed of polypropylene, offers high absorption characteristics suitable for a variety of applications. These include air filtration, waste management, heat insulation, and environmental restoration efforts such as desert greening. Intelligent NanoFiber serves critical sectors such as public safety and defense, providing solutions that enhance safety and efficiency in addressing environmental and health-related challenges.

Kismet Technologies specializes in innovative material technologies designed for effective infection control on surfaces. The company has created NanoRAD, a nanotechnology that maintains pathogen-free surfaces for extended periods, significantly reducing the risk of illness. This technology is safe for human contact and effectively combats harmful germs, including MRSA and norovirus. By utilizing Kismet's solutions, users can minimize infections from surfaces while also contributing to environmental sustainability by decreasing chemical release and plastic waste.

Diamante is a company based in Verona, Italy, that specializes in the development and manufacturing of diagnostic devices for autoimmune diseases, utilizing innovative nanomaterials. Founded in 2016, the company leverages plants as bioreactors to produce nanoparticles derived from modified plant viruses. This approach allows Diamante to create advanced tools for diagnosing and potentially treating autoimmune conditions, focusing on sustainable and efficient production methods. Through its research and development efforts, Diamante aims to contribute significantly to the field of autoimmune disease therapy.

Gelatex is a materials technology company based in Estonia, founded in 2016 and incorporated in the UK in 2019. The company specializes in producing bio-based nanofibers using a patented technology that allows for large-scale production at significantly lower costs. Gelatex's nanofibers are derived from gelatin sourced from low-value waste in the meat and leather industries, ensuring that its products are environmentally friendly and made from natural, non-toxic substances. Initially focused on developing eco-friendly leather-like textiles, the company recognized the broader applications of its technology during the COVID-19 pandemic, leading to a strategic pivot. Gelatex's innovative solutions have potential applications in various fields, including tissue engineering, cultured meat production, bio-based filtration, energy storage, and wound care.

Graphene Composites Ltd (GCL), established as a startup in the realm of nanotechnology, specializes in the development of advanced composite materials. In collaboration with the UK government-funded Graphene Application Centre at CPI, GCL combines graphene, renowned for its exceptional strength, and aerogel, recognized for its lightweight nature and superior insulation properties, to create innovative composites. These composites aim to exhibit strength roughly 100 times that of steel while maintaining a weight less than one-hundredth, targeting applications in sectors such as aerospace composites, renewable energy, and armor.

Nautilus Defense specializes in the creation and manufacture of advanced textile and composite-integrated systems aimed at monitoring structural assets and their environments. The company develops integrated maritime surveillance systems and cospas-sarsat meosar global deployment solutions. Its offerings include strain-sensing yarns, antennas, wearable systems, deployable systems, device arrays, and micrometers. Nautilus Defense is committed to rapid experimental development, delivering innovative material-based capabilities that enhance the performance of textile-integrated systems for its clients.

Veri Nano is a bionanotechnology company focused on developing innovative nanotechnologies applicable across various industries. Founded by a team of innovators and serial entrepreneurs, the company specializes in utilizing diverse biomaterials as building blocks to create advanced systems. Its product offerings include nanoengineered hydrogels, nanosized molecular delivery systems, and nanocomposite materials. By addressing key challenges in medicine and other sectors, Veri Nano aims to facilitate the integration of nanotechnology into business practices, enabling growth and advancement in multiple fields.

Parx Materials recognized a growing demand for plastics with antibacterial/antimicrobial properties and from their expertise they knew that the available solutions to achieve such materials were not suitable for large-scale application/adoption because of their possible harmful effects on humans, animals or the environment as a whole. They had foreseen the dangers, insecurities and disadvantages of these solutions. Over four years of dedicated biomimetic research has been invested to create a 100% safe and biocompatible technology to inhibit the growth of bacteria on the surface of plastic with the use of a Biomimetic approach in the design and engineering of the materials. The discoveries and inventions done during this research are truly unique and groundbreaking. A team of 11 professors, scientists and researchers with decades of experience in the field of Nano- and biotechnologies and skilled in chemical analyses and chemical-physical and microbial analyses have been working together with a renown European university for chemistry. The result is a worldwide patent-pending innovation for highly effective plastics with an antibacterial/antimicrobial effectiveness rate of 98-99% measured according to ISO 22196 and most of all: safe. Parx Plastics Sanipolymers are safe for humans, safe for animals and safe for the environment.

En Solución is a company that focuses on enhancing food safety through the integration of innovative nanotechnology and advanced sensing and control systems. The company's current initiatives involve the development of a high-concentration nanobubble generating device, which operates with recirculating and regenerative functions to produce effective nanobubbles in a wash water bath. This technology aims to improve the efficacy of pathogen elimination by utilizing powerful agents in a safer and more controlled manner. By offering novel cleaning and sanitizing methods, En Solución enables clients in the agriculture industry to replace traditional post-harvest chlorine washes with more advanced and effective solutions.

Grapheal is a Medtech startup focused on developing innovative embedded and wearable biosensors designed for modern healthcare applications. Leveraging advanced graphene transistors, Grapheal's devices enable accurate and affordable field diagnostics and remote patient monitoring. Their biosensors, which are minimalistic in design and integrated with wireless connectivity, allow for the precise detection of biomarkers and pathogens, all accessible through a smartphone. The company’s approach encompasses the entire value chain, from synthesizing proprietary sensing nanomaterials to the integration of sensor technology with embedded data analysis and software development, thus facilitating enhanced medical oversight for professionals.

Integricote is a manufacturer specializing in nanocoating materials designed to provide robust protective coatings that covalently bond to various substrates. The company offers a range of innovative products, including sealers infused with additives that create a mold and mildew resistant finish, ensuring surfaces remain fresh and durable over time. Additionally, Integricote produces specialized cleaners aimed at rejuvenating areas affected by water damage, such as those impacted by flooding or heavy rains. By utilizing hydrophobic nano-coating technology, Integricote's products effectively repel stains and water, enhancing the quality and longevity of surfaces and structures for its clients.

Veri Nano is a bionanotechnology company focused on developing innovative nanotechnologies applicable across various industries. Founded by a team of innovators and serial entrepreneurs, the company specializes in utilizing diverse biomaterials as building blocks to create advanced systems. Its product offerings include nanoengineered hydrogels, nanosized molecular delivery systems, and nanocomposite materials. By addressing key challenges in medicine and other sectors, Veri Nano aims to facilitate the integration of nanotechnology into business practices, enabling growth and advancement in multiple fields.

VoltXon introduces a new kind of NanoGenerator energy harvester to the market and develops a life-long and battery-free cardiac pacemaker.

Anavo Medical is a developer of innovative pharmaceutical products utilizing advanced nanotechnology to enhance wound healing and reduce complications associated with skin grafts. The company's flagship offering is a nanoparticle-based paste that contains bioactive nanoparticles suspended in a user-friendly matrix. These nanoparticles, which include metal oxides, possess anti-inflammatory and neo-angiogenic properties that promote the regeneration of blood vessels and mitigate inflammation. By leveraging these capabilities, Anavo Medical aims to improve patient safety and outcomes in surgical procedures, particularly in the healthcare and skin transplant sectors, thereby facilitating quicker healing and minimizing the risk of complications related to skin transplantation.

AeroShield specializes in the production of super-insulating, nanoporous glass materials designed for energy-efficient windows. Utilizing silica aerogel, AeroShield's products offer optical clarity akin to traditional glass while delivering superior insulation, making them 50% more effective than conventional double-pane windows. This innovative approach not only enhances thermal comfort but also significantly improves energy performance, allowing window manufacturers to meet sustainability and compliance objectives. Additionally, the payback period for AeroShield's materials is up to five times faster than that of similarly performing windows, making them a compelling choice for the modern market.

SolGro is a company focused on the development of nanomaterials and nanotechnology, specifically aimed at enhancing agricultural productivity. The company specializes in creating advanced greenhouse canopies that incorporate innovative nano-materials into their glazing. This technology is designed to convert wasted sunlight into usable light, thereby increasing plant photosynthesis. As a result, farmers can benefit from reduced harvest times, improved crop yields, and enhanced quality of their produce. Through its services and products, SolGro aims to significantly impact the agricultural sector by optimizing the growing conditions for various crops.

Nanochon is a medical device company focused on developing innovative solutions for treating cartilage damage in joints. Utilizing 3D printing technology and proprietary nanomaterials, the company aims to create implantable devices that replace lost or damaged cartilage and stimulate new tissue growth. This approach enables healthcare providers to offer cost-effective, on-demand treatments tailored to young and active patients suffering from knee injuries or diseases.

ZeoVation Inc. is a manufacturer based in Columbus, Ohio, specializing in nanozeolites and hierarchical zeolites. Founded in 2016, the company focuses on enhancing consumer products across various sectors, including skincare, home care, healthcare, and water purification. ZeoVation produces ready-to-use zeolite materials that improve the efficiency of water softeners and filtration systems, as well as contribute to the development of antimicrobial and antiviral products. Their innovative materials can be integrated into sprays, coatings, packaging, plastics, paper, and textiles, providing long-lasting protection against pathogens, including antibiotic-resistant bacteria and viruses. ZeoVation is committed to supporting research and development efforts in various industries, leveraging the unique properties of its zeolites to create safer and cleaner products.

Multiscale Systems produces industrial innovations through technical engineering services and a robust in-house R&D program. The company specializes in metamaterial composites and focuses on advanced manufacturing.

EMet Nanotech is a company that specializes in advancing the field of cryo-electron microscopy (cryo-EM) by significantly enhancing the sample preparation process. Its innovative PicoCell technology replaces traditional multi-step robots with a single, consumable imaging grid, streamlining the preparation to be up to 20 times faster and more cost-effective. This breakthrough enables biopharmaceutical firms to accelerate their drug discovery efforts, facilitating a deeper understanding of diseases and the development of targeted therapies. By simplifying the workflow and improving reproducibility, EMet Nanotech aims to contribute to more effective therapeutic solutions in the biopharma sector.

Swistor is a company focused on developing high-energy, ultra-fast charging battery replacements that significantly enhance charging speeds for electronic devices, aiming to charge in under two minutes. By utilizing carbon nanotube supercapacitors, Swistor's technology offers greater energy density and longevity compared to traditional batteries. This innovation not only extends the battery life of various electronic systems but also prioritizes the use of environmentally friendly and safe materials. The company targets major mobile phone providers and aims to penetrate the emerging market of self-powered Internet of Things (IoT) devices, positioning itself as a leader in sustainable energy solutions for modern electronics.

Resistell AG is a Swiss company founded in 2018, based in Muttenz, specializing in the development and marketing of innovative diagnostic devices for antibiotic susceptibility testing. The company's platform employs advanced nanomotion technology to detect the movement of living bacterial cells, allowing for the rapid identification of bacterial resistance to antibiotics. This method serves as an alternative to traditional culture-based antibiograms, enabling healthcare providers to administer appropriate antibiotics in a timely manner, ultimately improving patient outcomes.

Folia Water, Inc., established in 2016 and based in Pittsburgh, Pennsylvania, is a manufacturing company specializing in affordable water filtration solutions. The company's core product, Folia Filters™, is an innovative water filter made from antimicrobial filter paper infused with silver nanoparticles. This patented technology, which transforms ordinary paper into a super material, enables Folia Water to produce low-cost filters that reduce waterborne pathogens, making clean drinking water accessible to a broader range of consumers, particularly those in developing regions. The company's mission is to improve global health and sustainability by providing high-quality, affordable water filtration products.

ALAnostics is a specialty biopharmaceutical company that originated as a spin-off from the University of Geneva. It focuses on developing innovative tumor painting technology aimed at enhancing the surgical treatment of breast cancer. The company’s proprietary approach utilizes nanomedicines to create a fluorescent dye that targets early-stage tumors, facilitating real-time identification and removal during surgery. This technology, based on 5-ALA prodrugs, supports fluorescence-guided surgical procedures and incorporates light-activated antimicrobials, ultimately improving surgical outcomes and increasing the likelihood of saving patients' lives by ensuring complete tumor removal.

DetraPel, Inc. is a cleantech advanced materials company based in Framingham, Massachusetts, founded in 2013. The company specializes in the synthesis and manufacture of PFAS-Free protective coatings, offering a hydrophobic liquid repellent spray designed to protect various objects from spills, stains, and dirt. Utilizing advanced nanotechnology, DetraPel's spray provides a non-flammable, non-toxic, and non-corrosive solution that is also resistant to ultraviolet light, rust, and ice. This innovative product allows for the safe and effective cleaning of fabrics and shoes without compromising their texture or material integrity.

Blue Fairy Med is a wearable manufacturing company focused on developing innovative medical devices for neonatal care. Their primary product is a sophisticated infant care system designed to monitor vital signs of premature babies in the Neonatal Intensive Care Unit (NICU). This system integrates various components, including wires, adhesive electrodes, sensors, and clothing, into a single soft and smart textile garment. By enabling wireless monitoring of vital parameters, Blue Fairy Med's technology facilitates a more approachable and progressive treatment approach, allowing healthcare professionals to enhance the care and welfare of premature infants and establish a new standard in neonatal care.

SurgePower Materials is a green technology company focused on producing high purity graphene, a specialized carbon-based nanomaterial, from renewable resources. The company employs a cost-effective and environmentally friendly manufacturing process to create its nanomaterials, which are designed to enhance the performance of advanced sustainable products, particularly in the realm of green energy storage technologies. SurgePower Materials aims to redefine the graphene market by positioning itself as a leader in the global graphene sector, supported by a dedicated team of inventors, business directors, project managers, and researchers.

Guardion is a technology company specializing in advanced sensor technology, particularly in the development of radiation detectors that utilize the quantum properties of nanomaterials. This innovative approach allows Guardion to create low-cost, highly sensitive, and energy-efficient detectors suitable for large-scale deployment, especially in urban environments. The company focuses on applications that demand high sensitivity and miniaturization, providing analytical instruments and chemical detectors that serve various industries, including aerospace, healthcare, and national security. Guardion has received recognition for its contributions to the field, winning multiple awards such as the MassChallenge Gold Prize and the Technology in Space Prize from CASIS and Boeing. Additionally, the company participated in the inaugural cohort of the Techstars Autonomous Tech Accelerator, which is sponsored by the Air Force.

Nanosynex is a diagnostic test that checks bacterial resistance to antibiotics in a record time, using a phenotypic approach that involves microfluidic techniques and fluorescent-based analysis. The test helps doctors determine faster (same-day results) the most appropriate antibiotic treatment for their patients, helping them recover in a shorter time and preventing the spread of resistant bacteria in the environment. By limiting prolonged hospitalization, Nanosynex allows to save significant healthcare costs.

Klahas is developing nanosensors for gas detection. To date billions of people mainly in cities unknowingly breath polluted air. The gas sensor market worth $2.5B has 6% annual growth. Their patented technology, a nano-sized molecule based gas sensor for dangerous gases (NOx, NH3, COx, benzol) monitors air pollution and can be integrated in smart devices, especially wearables. Standard fabrication technologies are used to fabricate a low power consumption, highly sensitive nanotech sensors that will enter a market with annual growth rate of 10-15%.

IbtiCare is a company that has developed an innovative antibacterial technology using Physical Vapor Deposition (PVD). This advanced method enables the coating of various surfaces with nanoparticles that effectively combat all types of drug-resistant bacteria. The technology is distinguished by its rapid reactivity, stability, and durability, making surfaces not only antibacterial but also self-sterilizing. IbtiCare's solutions have undergone clinical trials and received validation from leading healthcare professionals, positioning the company as a significant contributor to the fight against bacterial infections. The focus on creating safe and effective antibacterial solutions underscores IbtiCare's commitment to enhancing public health.

Nanogence SA is a Swiss company established in 2017, specializing in the development of innovative material solutions for the construction sector. Based in Renens, the company focuses on creating synthetic, tailor-made materials utilizing advanced nanotechnology and chemistry. Its patented additive formulations enhance the performance of cement and concrete, significantly improving their binding efficiency while also aiming to reduce carbon emissions by up to 50%. By providing environmentally friendly chemicals and additives, Nanogence enables manufacturers in the construction industry to lower costs, enhance durability, and contribute to sustainable practices. The company operates within a rapidly growing global construction market, which underscores the importance of its contributions to more efficient and eco-friendly building materials.

Lux Labs specializes in the development of advanced optical materials, utilizing cutting-edge nanophotonics and polymer fabrication techniques. The company's flagship innovation is a transparent display technology designed to transform any window or clear surface into a projection screen. This proprietary technology employs optical angular selective film and wavelength-selective scattering film, enabling consumers to retrofit various clear substrates for use as fully transparent displays.

ConquerX is a biotechnology company focused on advancing precision medicine through innovative molecular profiling solutions for clinical trials. The company's flagship product, EbeGen, is an electro-chemical biosensor designed to detect multiple molecular targets, including DNAs, RNAs, and microRNAs, simultaneously without the need for sequencing or quantitative PCR, thus offering a cost-effective alternative to existing technologies. Additionally, ConquerX has developed a pan-cancer test that differentiates cancerous cells from healthy ones, utilizing high-throughput genomic and proteomic profiling alongside proprietary nanotechnology. This tool enables oncologists to effectively screen for commonly known biomarkers across various cancer types, thereby enhancing the cancer diagnosis process.

Biomicrogels Group is an environmental biotechnology company specializing in the development and patenting of biomicrogels derived from agricultural waste, such as sugar beet, apple, and sunflower pomace. These biomicrogels are designed to tackle global environmental challenges by providing innovative solutions for produced water treatment, cutting fluid separation, vegetable oil extraction, and the cleaning of oil spills both at sea and on land. The company's unique nanoscale organic polymer particles possess surface-active properties that allow them to encapsulate minerals, vegetable oils, and fats, effectively separating these substances from water and solid surfaces. This technology not only enhances pollution purification processes but also facilitates the recycling of materials back into the technological cycle. Additionally, Biomicrogels Group produces a line of eco-friendly household cleaning products under the brand WONDERLAB, further contributing to sustainable practices.

HICS Inc., founded in 2014, specializes in real-time, high-precision measurement and inspection technologies. The company has pioneered machine vision systems utilizing cutting-edge 3D-NDM/R and 3D-NDM/T technology, which enable quantitative analysis of nanoscale defects and foreign materials. HICS serves the LED panel manufacturing industry, offering advanced inspection solutions that enhance speed and accuracy in detecting nano-scale issues.

Inspecto Solutions Ltd is an innovative company that develops a portable nanoscale scanner designed to detect food contaminants quickly and efficiently. Founded in 2016 and headquartered in Israel, Inspecto Solutions aims to enhance food safety by providing a solution that allows farmers, producers, suppliers, buyers, retailers, and quality assurers to receive rapid results. Unlike traditional detection methods that are often expensive and complex, Inspecto's technology enables users to check for early signs of contamination within minutes and at a significantly lower cost. The company's platform also includes a cloud-based application that integrates big data analytics and blockchain technology, ensuring secure data storage and facilitating real-time analysis for multiple contamination parameters. This comprehensive approach helps improve business performance by enhancing traceability and quality assurance throughout the food supply chain.

PolyDrop is a company that specializes in the development of conductive polymer additives aimed at enhancing coatings, composites, and batteries. Originating from the University of Washington, PolyDrop has patented a material science development process that is now utilized by major players in the electronics and coatings industries. The company focuses on creating safe, stable, and affordable conductive polymers that provide anti-static and anti-corrosion protection at low loading levels. These additives enable users to convert conventional coatings and plastics into static dissipative materials suitable for various applications, including textiles, flooring, and marine environments. Through its innovative solutions, PolyDrop aims to improve the performance and safety of existing materials in multiple sectors.

Novarials Corporation, based in Woburn, MA, specializes in the large-scale production and processing of high-quality one-dimensional nanomaterials. Their portfolio spans ceramic, semiconducting, metallic nanowires, nanotubes, nanosheets, and nanoporous materials, catering to diverse research and development needs across industries.

Vecoy Nanomedicines Ltd., a privately held company, incorporated in Israel in 2010, is a leading company in the application of nanomedicine technologies to the complex issues of viral diseases. The Vecoy technology will fundamentally change the treatment of viral infections by administering novel nano-scale virus-traps that capture and destroy viruses.

EnerLeap is a patented, new lithium ion battery technology. In today's lithium ion batteries, the powder binders break down quickly, stunt performance and jeopardize safety. EnerLeap replaces these inefficient binders with a rigid 2D titanium silicide nanonet. The result is a lighter weight, faster charging, longer lasting and safer battery. We have lab scale prototypes and are currently planning to enter the $12B global lithium ion market through the consumer electronic space.

Cellanyx is a diagnostics company focused on advancing cancer detection through innovative technologies. By integrating matrix biology, nanomedicine, and computational methods, Cellanyx has developed a live-cell biomarker-based diagnostic test that assesses the oncogenic and metastatic potential of tumors, particularly in prostate, skin, and breast cancers. The company's diagnostic solution provides healthcare professionals with objective prognostic metrics, which enhance treatment decision-making for patients undergoing monitoring or surgical interventions. Cellanyx's approach includes high-content imaging and machine learning algorithms to generate personalized clinical scores that aid in risk stratification, especially for men with low and intermediate-grade prostate cancer. Additionally, the company is positioned to utilize its technology for compound discovery, identifying less toxic treatments that effectively mitigate cancer cell growth and metastasis, with the goal of reverting malignant cells to a more normal state.

NBD Nanotechnologies, Inc. is a manufacturer of surface wettability coatings and additives designed to enhance the performance of various materials. Founded in 2012 and headquartered in Lexington, Massachusetts, the company offers a diverse product portfolio that includes RepelShell, RepelFlex Antimicrobial, RepelFlex Soft-Touch, NanoGlue, RepelFlex Hard-Coat, Invisiprint, and RepelFlex Leather. These products are engineered to modify surface properties, improving functionalities such as heat transfer, condensation control, fog capture, de-misting, and anti-scaling performance. NBD Nanotechnologies focuses on providing innovative solutions that create ultra-durable and functional surface characteristics for glass and plastic materials, catering to a range of commercial partners.

Cerahelix, Inc. is a manufacturer of ceramic membrane filters designed for high-quality water purification and resource recycling. Established in 2011 and based in Orono, Maine, the company specializes in bio-derived products that utilize patented DNA template technology to create sub-nanometer pores in ceramic membranes. This innovative design enables the filtration of minute particles, allowing water purification agencies to effectively separate salts, metal ions, and other impurities at the molecular level. Cerahelix offers a range of filtration products, including single-channel elements for laboratory and pilot-scale studies, as well as multi-channel elements for commercial applications. Additionally, the company provides filter element housings and laboratory test systems to support small-scale research and development. Its products serve various industries, including food and beverage, pharmaceuticals, mining, and waste-to-energy.

NanoLab brings world-class molecular diagnostics into the point of care market. They have a patent pending device capable of becoming a fully featured platform diagnostic tool. They also have an attractive, $1.2 billion initial market with cardiac enzyme panel tests to diagnose heart attacks. They use nanoscale magnetic sensors and tags to achieve sensitivities over 20 times greater than the current gold standard, with results available in 15 minutes in a purely portable package.

Imbed Biosciences, Inc. is a medical device company specializing in advanced technologies for integrating bioactive molecules into wound dressings and surgical implants. Founded in 2010 and based in Madison, Wisconsin, the company has developed antibacterial silver nanofilms that enable biologic dressings to release non-toxic silver over extended periods, effectively preventing infections in wounds. This innovation is aimed at improving wound management and expediting healing, addressing a significant market opportunity in the U.S. and Europe valued at $3 billion. As a spin-off from the University of Wisconsin-Madison, Imbed combines expertise from engineers, veterinary scientists, and medical surgeons, collectively bringing over 25 years of experience in clinical wound management. The company’s focus on antimicrobial wound matrices supports medical practitioners in treating complex wounds, ultimately enhancing patient care and outcomes.

Privo Technologies is a biotechnology company focused on developing a novel class of targeted treatments utilizing their proprietary nano-engineered platform. This platform, based on breakthroughs in nanotechnology and material science from MIT's Langer laboratory, aims to create effective therapies for various medical conditions while minimizing the harmful side effects typically associated with traditional treatments. Privo specializes in drug delivery via mucosal routes, particularly targeting the oral cavity. Their initial product candidate addresses the significant unmet need in the treatment of oral cancer, with plans to expand their pipeline to include therapies for oncology, infectious diseases, and radiation. Operating from facilities in the greater Boston area, Privo Technologies is dedicated to improving patient outcomes and enhancing compliance through innovative drug delivery methods.

Novophage specializes in developing biological solutions to address significant industrial infrastructure challenges caused by biofilms, which are communities of bacteria that hinder heat transfer, lead to corrosion, and contribute to biofouling and various diseases. These issues incur substantial economic costs in the United States. Existing methods to combat biofilms often rely on toxic or corrosive chemicals that can harm the environment. Novophage's innovative approach features a first-in-class, patent-pending anti-biofilm solution that is both environmentally friendly and highly effective. By leveraging expertise in synthetic and systems biology, the company utilizes a biological nanoparticle that harnesses the bacteria's own mechanisms to generate active agents targeting the biofilm. This solution can be integrated with existing antimicrobials, enhancing energy efficiency in heat transfer systems and extending the lifespan of critical infrastructure.

Fluorescent Nanoscopy is a breakthrough technology for optical microscopy suited for live cell imaging with tens times enhanced resolution. It helps develop new drugs and materials, achieve breakthrough results in fundamental research and to improve clinical and QA tests. This can be done by both increasing resolution in cell research and increasing data density on surfaces of microarrays. The technology has a strong IP protection and gives an opportunity to create new markets.