MassChallenge is a global nonprofit startup accelerator headquartered in Boston, Massachusetts, established in 2009. It supports early-stage entrepreneurs across various industries, including technology, healthcare, and social impact, by providing mentorship, resources, and networking opportunities. With locations in Israel, Mexico, Switzerland, Texas, and the UK, MassChallenge connects high-potential startups with industry experts and investors to foster innovation and facilitate growth. The accelerator operates on a non-equity model, allowing entrepreneurs to maintain full ownership of their companies while benefiting from strategic partnerships and tailored training programs. Through its diverse initiatives, such as targeted accelerator programs like MassChallenge HealthTech and FinTech, the organization aims to drive impactful change and enhance the global innovation ecosystem.
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Flourish Science
Non Equity Assistance in 2023
Flourish Science is a digital mental health organization that was founded in order to deliver personalized and community-oriented well-being knowledge and practices based on social psychology, positive psychology, and behavioral science.
Innsightful
Non Equity Assistance in 2023
Innsightful offers a comprehensive digital health solution aimed at managing and alleviating mental health challenges, particularly for students. The company develops wearable devices that monitor and detect symptoms of anxiety and stress, utilizing artificial intelligence and machine learning to provide automated, early detection of heightened stress levels. These devices integrate biometrics to give users personalized insights, fostering a deeper understanding of their mental health. Additionally, Innsightful facilitates access to therapists for tailored recommendations and progress assessments, transforming how individuals approach their mental well-being.
InnoPsych
Non Equity Assistance in 2022
InnoPsych is a mental health platform focused on addressing racial disparities in therapy and promoting emotional wellness within communities of color. The company provides a national directory of therapists of color, enabling individuals to easily find mental health professionals based on geographic location, therapy type, insurance, and personal background. InnoPsych also offers engaging programming designed to reshape conversations about mental health in BIPOC communities, along with wellness products that teach emotional wellness strategies. Through these initiatives, InnoPsych aims to transform the experience of therapy and make mental health resources more accessible and relevant to diverse populations.
Opeeka
Non Equity Assistance in 2021
Opeeka is a developer of AI-based mental health assessment software aimed at enhancing health and human services. The company's platform is designed for healthcare professionals, enabling them to transform assessment data into personalized treatment and care plans. By focusing on person-centered care, Opeeka's software assists mental and behavioral health care agencies in effectively planning and guiding interventions while tracking individual progress in recovery and resilience. Through its innovative approach, Opeeka aims to make a positive impact on the lives of children, adults, and families.
Canopie
Non Equity Assistance in 2021
Canopie is a digital platform focused on addressing maternal depression and anxiety through customized, audio-based programs and automated coaching. By utilizing clinically validated therapeutic techniques, including adaptations of cognitive behavioral therapy and compassion-focused treatment, Canopie aims to prevent and manage maternal mental health disorders effectively. The platform collaborates with cities, payers, health systems, and healthcare providers to deliver accessible and affordable care for mothers, addressing significant barriers such as cost, scheduling, time constraints, and stigma associated with seeking help. Through its innovative approach, Canopie is dedicated to supporting pregnant women and new mothers in overcoming common mental health challenges.
Kintsugi
Non Equity Assistance in 2021
Kintsugi is a developer of innovative voice biomarker software that identifies signs of depression and anxiety from short clips of free-form speech. The company's technology aims to enhance mental healthcare infrastructure by validating voice biomarkers, which assists medical practitioners in addressing mental health care gaps within risk-bearing health systems. Recognized for its advancements in artificial intelligence, Kintsugi has received multiple awards and was named one of Forbes' Top 50 AI companies to watch in 2022. By streamlining the detection of mental health issues, Kintsugi seeks to improve patient outcomes and ultimately save time and lives.
SageSurfer
Non Equity Assistance in 2021
SageSurfer operates a mental healthcare platform designed to empower individuals in overcoming behavioral health challenges by fostering collaboration among their caregivers. The platform facilitates comprehensive, coordinated, and outcome-driven personalized care for mental health and addiction treatment. It enables consumers to actively participate in their care planning, ensuring they have a stronger voice in their treatment process. By centering the consumer in the recovery plan and providing access to their entire care team, SageSurfer aims to create a supportive healthcare environment where individuals are not alone in their journey towards recovery and can easily access help when needed.
Voi
Non Equity Assistance in 2021
Voi Technology AB, established in 2018 and headquartered in Stockholm, Sweden, specializes in micro-mobility services. It offers electric scooters and bikes for urban commuters, promoting sustainable transportation through its mobile application.
Goaceit
Non Equity Assistance in 2021
Goaceit is a web application that focuses on enhancing the mental aspects of performance for users, particularly students aged 15 to 25 who face significant stress during critical testing moments. The platform offers personalized and interactive training aimed at improving essential soft skills such as self-awareness, self-confidence, and stress management. By leveraging psychology tools and machine learning, Goaceit provides a comprehensive online program that helps users develop mental toughness and maintain control under pressure, ultimately contributing to their success and well-being.
Butterflly Health
Seed Round in 2021
Sanitas Health is dedicated to enhancing mental health services by focusing on accessibility and inclusivity for historically marginalized communities and Medicaid populations. The company has developed an AI-driven platform that provides culturally and gender-sensitive coaching and counseling, aiming to improve mental health outcomes. In addition, it connects individuals with therapists and experts in behavioral health and autism, facilitating direct access to care. This cloud-based telehealth platform also offers personalized self-help resources and educational content, along with a social network that links users with shared experiences, fostering a supportive community. Through its innovative approach, Sanitas Health addresses the multifaceted aspects of mental and physical well-being, ultimately aiming to empower individuals to enhance their overall health.
UpLift Health
Non Equity Assistance in 2021
UpLift Health Inc., known as UpLift, is dedicated to developing a digital application aimed at treating depression through cognitive behavioral therapy (CBT). Founded in 2018 and based in Atlanta, Georgia, UpLift offers a structured program that consists of twelve weekly sessions, each lasting approximately 40 minutes. During these sessions, users engage with chatbot-guided interactions that help them learn effective coping skills. In addition to the sessions, the application provides daily tools and challenges that allow users to apply what they have learned in their everyday lives. A pilot study has demonstrated that this program can reduce symptoms of depression by 52%. UpLift's mission is to significantly impact mental health by assisting one million individuals in overcoming depression.
PainPal
Pre Seed Round in 2020
PainPal is a behavioral health platform specifically designed for individuals experiencing chronic pain. It offers a personalized and gamified approach to on-demand Cognitive Behavioral Therapy (CBT-CP), which has been shown to effectively reduce pain and enhance functioning. By utilizing this innovative telebehavioral health platform, PainPal provides a safe and evidence-based alternative for patients, addressing the growing concerns related to chronic pain management and the opioid crisis. The platform aims to redefine treatment possibilities for those suffering from chronic pain, making therapy more accessible and engaging.
Litesprite
Non Equity Assistance in 2020
Litesprite, Inc. is a company based in Bellevue, Washington, that develops mobile games aimed at helping individuals manage chronic health conditions such as stress, anxiety, and depression. Its primary product, Sinasprite, is a video game designed to assist users in navigating their mental health treatment by providing resources and coping mechanisms tailored to their needs. This platform allows healthcare providers to collect and analyze data on player behavior, enabling them to identify effective strategies and improve treatment outcomes. Litesprite's innovative approach combines proven medical practices with engaging gameplay, fostering greater patient participation and support networks. The company has also been recognized for its potential impact on health management, having won an award in the Robert Wood Johnson Foundation's Games to Generate Data Challenge.
Butterflly Health
Non Equity Assistance in 2020
Sanitas Health is dedicated to enhancing mental health services by focusing on accessibility and inclusivity for historically marginalized communities and Medicaid populations. The company has developed an AI-driven platform that provides culturally and gender-sensitive coaching and counseling, aiming to improve mental health outcomes. In addition, it connects individuals with therapists and experts in behavioral health and autism, facilitating direct access to care. This cloud-based telehealth platform also offers personalized self-help resources and educational content, along with a social network that links users with shared experiences, fostering a supportive community. Through its innovative approach, Sanitas Health addresses the multifaceted aspects of mental and physical well-being, ultimately aiming to empower individuals to enhance their overall health.
Healium
Pre Seed Round in 2020
Healium is a mental fitness tool that offers a drugless approach to managing anxiety, sleep, addiction, and burnout. The company utilizes patented technology that connects to biometric data from consumer wearables, such as smartwatches and EEG headbands, allowing users to monitor their brainwaves and heart rate. This information is used to create a reactive, immersive media experience that adapts to the user's bio-data. Healium's unique platform has been validated by eight peer-reviewed studies, demonstrating its effectiveness in reducing anxiety and improving mood within minutes. By leveraging existing sensors and devices, Healium provides a controlled virtual and augmented reality environment for users seeking to enhance their mental well-being.
Marigold Health
Grant in 2020
Marigold Health operates a social network community platform designed to provide text-based group therapies for individuals facing mental health and substance use challenges. The platform facilitates anonymous support groups, allowing patients to engage with one another and receive guidance from coaches who have personal recovery experiences. By leveraging AI-augmented chat support, Marigold Health enhances the capacity of care teams while ensuring that patients receive personalized, stigma-free assistance. The company collaborates directly with treatment providers and managed care organizations within the Medicaid market to improve access to on-demand group therapies and foster a supportive community for recovery.
WorkingWell
Non Equity Assistance in 2020
WorkingWell is a research-based, feasibility-tested mobile app to help people with mental illness succeed at and sustain employment. WW users set and achieve goals, establish routines, learn to get along with others and develop coping skills contributing to workplace success and tenure. WW fills the gap between what we know about mental illness and employment and what we do about it, to enhance individual outcomes and reduce employer/employee assistance, a state agency, and provider costs.
Limbix
Venture Round in 2020
Limbix is a prescription digital therapeutic company focused on developing mental health treatments specifically for adolescents. The company combines clinical expertise with technological innovation, leveraging a diverse team of clinicians, product designers, researchers, and engineers to create effective therapeutic solutions. Limbix's flagship product, SparkRx, is a digital therapeutic designed to assist licensed healthcare professionals in treating young patients dealing with depression, anxiety, and other mental health issues. By offering evidence-based interventions, Limbix aims to enhance the lives of teenagers facing mental health challenges.
Marigold Health
Non Equity Assistance in 2019
Marigold Health operates a social network community platform designed to provide text-based group therapies for individuals facing mental health and substance use challenges. The platform facilitates anonymous support groups, allowing patients to engage with one another and receive guidance from coaches who have personal recovery experiences. By leveraging AI-augmented chat support, Marigold Health enhances the capacity of care teams while ensuring that patients receive personalized, stigma-free assistance. The company collaborates directly with treatment providers and managed care organizations within the Medicaid market to improve access to on-demand group therapies and foster a supportive community for recovery.
Eleos Health
Non Equity Assistance in 2019
Eleos Health develops innovative health technology solutions aimed at enhancing decision-making for clinicians in the behavioral health sector. The company's AI-powered Speech-to-Insights system operates during mental health sessions to analyze voice data in real time. By gathering insights on patients through this voice technology, Eleos Health enables clinicians to deliver personalized, efficient, and cost-effective care. The automated nature of the system helps streamline the clinical process, ultimately supporting mental health professionals in providing the necessary care and support for their patients.
WorkingWell
Non Equity Assistance in 2019
WorkingWell is a research-based, feasibility-tested mobile app to help people with mental illness succeed at and sustain employment. WW users set and achieve goals, establish routines, learn to get along with others and develop coping skills contributing to workplace success and tenure. WW fills the gap between what we know about mental illness and employment and what we do about it, to enhance individual outcomes and reduce employer/employee assistance, a state agency, and provider costs.
Valera Health
Non Equity Assistance in 2018
Valera Health, established in 2015, operates a behavioral healthcare platform focused on delivering personalized mental health services to individuals with a range of conditions from mild to severe, including depression and schizophrenia. The company integrates digital technology and data science with traditional clinical services to enhance patient outcomes and address the needs of hard-to-reach populations. By providing a comprehensive approach that combines therapy, medication, and continuous connectivity with care teams, Valera Health aims to offer efficient mental healthcare solutions, particularly for employers seeking to improve access to mental health support for their employees.
BabyNoggin
Non Equity Assistance in 2018
BabyNoggin is a mental health screening application that empowers parents to self-screen their children's development using evidence-based tools. The application aligns with the recommendations of the American Academy of Pediatrics, allowing for effective tracking of developmental milestones. It facilitates the identification of children at risk for developmental delays and provides automatic scoring of screening results. Additionally, BabyNoggin supports the integration of these results into electronic medical records (EMR) systems, streamlining the referral process for children who require intervention services. By focusing on research-supported techniques, BabyNoggin aims to enhance parental involvement in monitoring their children's mental health and development.
HealthRhythms
Non Equity Assistance in 2017
HealthRhythms develops a mental health assessment and treatment platform that focuses on measuring and monitoring health conditions. Utilizing advanced machine learning and predictive analytics, the company offers innovative health assessments and personalized interventions aimed at enhancing the care delivery experience for patients, health plans, payers, and research organizations. Its platform enables continuous, objective monitoring of behavioral health, allowing for real-time tracking of mental health status. By anticipating clinical deterioration, HealthRhythms delivers tailored interventions based on individual patient profiles, assisting healthcare providers in effectively identifying, managing, and characterizing patients' mental health needs.
ReachMore
Grant in 2017
ReachMore application that treats anxiety created by trauma events.
Girls Health Champions
Grant in 2017
Girls Health Champions is an innovative, peer-to-peer education model where adolescent girls in India are trained to directly educate their peers about these important health topics, including nutrition, mental health, gender-based violence, menstruation, and reproductive health. Their peer educators ("Champions") are trained in focused curriculum which were created in partnership with leading pediatricians, psychiatrists, obstetricians and gynecologists, educational specialists, and school teachers in both the United States and India.
Marigold Health
Grant in 2017
Marigold Health operates a social network community platform designed to provide text-based group therapies for individuals facing mental health and substance use challenges. The platform facilitates anonymous support groups, allowing patients to engage with one another and receive guidance from coaches who have personal recovery experiences. By leveraging AI-augmented chat support, Marigold Health enhances the capacity of care teams while ensuring that patients receive personalized, stigma-free assistance. The company collaborates directly with treatment providers and managed care organizations within the Medicaid market to improve access to on-demand group therapies and foster a supportive community for recovery.
Spriteli
Grant in 2016
Spriteli is a digital health company which aims to reduce anxiety and elevate mood levels of our users through daily, 2 minute, video consultations. The video consultations are performed by a network of trained coaches. The calls consist of proprietary activities based on Mindfulness, Affirmation and CBT techniques. Initial beta results indicate we can improve outcomes and lower costs of traditional mental health delivery options. Currently collaborating with a major Boston Hospital.
Yana
Seed Round in 2016
Yana is a developer of an emotional wellbeing chatbot that supports individuals dealing with anxiety and depression in their mental health journey. The chatbot utilizes principles of Cognitive-Behavioral Therapy to provide users with practical tools and strategies for improving their mental wellbeing. It offers an automated conversational agent that evaluates users' moods and engages in daily conversations, helping them understand the factors influencing their emotions. Additionally, Yana can connect users to crisis hotlines or mental health professionals, facilitating access to further therapeutic support. This approach allows users to address negative thoughts and behaviors at any time, promoting a proactive attitude towards mental health.
Myndlift
Seed Round in 2015
Myndlift Ltd, founded in 2014 and based in Tel Aviv, Israel, develops innovative solutions for neurofeedback training, allowing users to connect with experienced practitioners from the comfort of their homes. The company integrates neurotechnology, behavioral psychology, and human care to enhance mental health treatment, making it accessible to tens of thousands of individuals through numerous mental health providers. Myndlift's technology measures brain wave activity and offers mind-controlled gamified exercises based on evidence-based techniques, primarily aimed at helping healthcare professionals assist patients with attention deficit hyperactivity disorder (ADHD) in improving their concentration and cognitive abilities.
Ginger
Seed Round in 2011
Ginger is a telemental health provider delivering evidence-based behavioral health coaching, therapy, and psychiatry from a smartphone. Ginger's on-demand system brings together behavioral health coaches, therapists, and psychiatrists, who work as a team to deliver personalized care, right through your smartphone. The app provides members with access to the support they need within seconds, 24/7, 365 days a year. Millions of people have access to Ginger through leading employers, health plans, and its network of partners.
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