MassChallenge is a global nonprofit startup accelerator headquartered in Boston, Massachusetts, founded in 2009. It supports early-stage entrepreneurs from various industries, including technology, healthcare, and finance, by providing mentorship, resources, and networking opportunities. With locations in countries such as Israel, Mexico, Switzerland, and Texas, MassChallenge operates a non-equity model, allowing startups to retain full ownership while benefiting from expert guidance and connections. The accelerator conducts various programs tailored to specific sectors, such as MassChallenge HealthTech and MassChallenge FinTech, which facilitate partnerships between startups and established enterprises to drive innovation and market growth. Through its extensive global network, MassChallenge aims to strengthen the innovation ecosystem and empower high-potential startups to create meaningful impact.
Innsightful offers a comprehensive digital health solution aimed at managing and alleviating mental health challenges, particularly for students. The company develops wearable devices that monitor and detect symptoms of anxiety and stress, utilizing artificial intelligence and machine learning to provide automated, early detection of heightened stress levels. These devices integrate biometrics to give users personalized insights, fostering a deeper understanding of their mental health. Additionally, Innsightful facilitates access to therapists for tailored recommendations and progress assessments, transforming how individuals approach their mental well-being.
Flourish Science
Non Equity Assistance in 2023
Flourish Science is a digital mental health organization that was founded in order to deliver personalized and community-oriented well-being knowledge and practices based on social psychology, positive psychology, and behavioral science.
Even Mind
Non Equity Assistance in 2023
Mobile app for tracking, understanding, and improving mental health. We're working on making mental healthcare more quantitative. If that sounds interesting to you, get in touch!
InnoPsych
Non Equity Assistance in 2022
InnoPsych is a mental health platform company that aims to change the face of therapy and disrupt racial disparities in mental health. Its offerings include a national therapist of the color directory, engaging mental health programming that aims to change how (BIPOC) communities talk about mental health, wellness products that teach emotional wellness strategies.
Kintsugi
Non Equity Assistance in 2021
Kintsugi is a developer of innovative voice biomarker software that identifies signs of depression and anxiety from short clips of free-form speech. The company's technology aims to enhance mental healthcare infrastructure by validating voice biomarkers, which assists medical practitioners in addressing mental health care gaps within risk-bearing health systems. Recognized for its advancements in artificial intelligence, Kintsugi has received multiple awards and was named one of Forbes' Top 50 AI companies to watch in 2022. By streamlining the detection of mental health issues, Kintsugi seeks to improve patient outcomes and ultimately save time and lives.
Opeeka
Non Equity Assistance in 2021
Opeeka is a developer of AI-based mental health assessment software aimed at enhancing health and human services. The company's platform is designed for healthcare professionals, enabling them to transform assessment data into personalized treatment and care plans. By focusing on person-centered care, Opeeka's software assists mental and behavioral health care agencies in effectively planning and guiding interventions while tracking individual progress in recovery and resilience. Through its innovative approach, Opeeka aims to make a positive impact on the lives of children, adults, and families.
Canopie
Non Equity Assistance in 2021
Canopie offers a digital platform that addresses symptoms of maternal depression and anxiety. It aims to prevent and address maternal mental health disorders through customized, audio-based programs and automated coaching using clinically validated, recommended therapeutic techniques. Canopie works with cities, payers, health systems, and providers to deliver effective, low-cost care to moms that works for them and can be easily scaled - tackling the key treatment barriers of cost, scheduling, time, and stigma.
SageSurfer
Non Equity Assistance in 2021
They leverage technology to empower people to partner with their full circle of caregivers in overcoming behavioral health challenges. They imagine a healthcare system where every member of the care team has the whole story on the consumer's needs and treatment and where the consumer is at the center of the recovery plan, resulting in a world where no one suffers alone, and where help is available at the click of a button.
Goaceit
Non Equity Assistance in 2021
Goaceit is a web application that focuses on enhancing the mental aspects of performance for users, particularly students aged 15 to 25 who face significant stress during critical testing moments. The platform offers personalized and interactive training aimed at improving essential soft skills such as self-awareness, self-confidence, and stress management. By leveraging psychology tools and machine learning, Goaceit provides a comprehensive online program that helps users develop mental toughness and maintain control under pressure, ultimately contributing to their success and well-being.
Butterflly Health
Seed Round in 2021
Sanitas Health is dedicated to enhancing mental health services by focusing on accessibility and inclusivity for historically marginalized communities and Medicaid populations. The company has developed an AI-driven platform that provides culturally and gender-sensitive coaching and counseling, aiming to improve mental health outcomes. In addition, it connects individuals with therapists and experts in behavioral health and autism, facilitating direct access to care. This cloud-based telehealth platform also offers personalized self-help resources and educational content, along with a social network that links users with shared experiences, fostering a supportive community. Through its innovative approach, Sanitas Health addresses the multifaceted aspects of mental and physical well-being, ultimately aiming to empower individuals to enhance their overall health.
UpLift Health
Non Equity Assistance in 2021
UpLift Health Inc., based in Atlanta, Georgia, specializes in developing a digital application aimed at treating depression through cognitive behavioral therapy (CBT). Founded in 2018, the company offers a structured program that consists of twelve weekly sessions, each lasting approximately 40 minutes, designed to teach users effective coping skills. The application incorporates chatbot-guided interactions, allowing users to engage with mental exercises and receive feedback. Additionally, it provides daily tools for users to apply learned skills in their everyday lives. Preliminary research indicates that UpLift's program can significantly reduce symptoms of depression, with a reported reduction of 52% in pilot studies. The company is focused on its mission to assist one million individuals in overcoming depression.
PainPal
Pre Seed Round in 2020
PainPal is a behavioral health platform specifically designed for individuals experiencing chronic pain. It offers a personalized and gamified approach to on-demand Cognitive Behavioral Therapy (CBT-CP), which has been shown to effectively reduce pain and enhance functioning. By utilizing this innovative telebehavioral health platform, PainPal provides a safe and evidence-based alternative for patients, addressing the growing concerns related to chronic pain management and the opioid crisis. The platform aims to redefine treatment possibilities for those suffering from chronic pain, making therapy more accessible and engaging.
Butterflly Health
Non Equity Assistance in 2020
Sanitas Health is dedicated to enhancing mental health services by focusing on accessibility and inclusivity for historically marginalized communities and Medicaid populations. The company has developed an AI-driven platform that provides culturally and gender-sensitive coaching and counseling, aiming to improve mental health outcomes. In addition, it connects individuals with therapists and experts in behavioral health and autism, facilitating direct access to care. This cloud-based telehealth platform also offers personalized self-help resources and educational content, along with a social network that links users with shared experiences, fostering a supportive community. Through its innovative approach, Sanitas Health addresses the multifaceted aspects of mental and physical well-being, ultimately aiming to empower individuals to enhance their overall health.
Litesprite
Non Equity Assistance in 2020
Litesprite builds mobile games to help people manage health conditions like stress, anxiety/depression, diabetes or asthma. We combine proven medical treatments with the engagement of mobile games. Our mission is to create experiences that increase individual participation, incorporate support networks, and provide self-help tools so a person can easily and affordably manage their health or that of their loved ones. Clinicians and community health organizations can analyze data to understand players’ underlying triggers, communicate with players, and improve individual and group level outcomes. While we will develop a suite of games to address several health conditions, our first game SinaSprite helps the 40 million Americans, especially adult women, diagnosed with anxiety/depression. Litesprite’s innovative approach to have large scale impact in health was recognized as a winner in the Robert Wood Johnson Foundation’s 2013 Games to Generate Data Challenge. Our team includes clinicians AND gaming experts. A compelling emotional experience is the primary driver to engage and expose players to treatment methods.
Healium
Pre Seed Round in 2020
Healium is a mental fitness tool that offers a drugless approach to managing anxiety, sleep, addiction, and burnout. The company utilizes patented technology that connects to biometric data from consumer wearables, such as smartwatches and EEG headbands, allowing users to monitor their brainwaves and heart rate. This information is used to create a reactive, immersive media experience that adapts to the user's bio-data. Healium's unique platform has been validated by eight peer-reviewed studies, demonstrating its effectiveness in reducing anxiety and improving mood within minutes. By leveraging existing sensors and devices, Healium provides a controlled virtual and augmented reality environment for users seeking to enhance their mental well-being.
WorkingWell
Non Equity Assistance in 2020
WorkingWell is a research-based, feasibility-tested mobile app to help people with mental illness succeed at and sustain employment. WW users set and achieve goals, establish routines, learn to get along with others and develop coping skills contributing to workplace success and tenure. WW fills the gap between what we know about mental illness and employment and what we do about it, to enhance individual outcomes and reduce employer/employee assistance, a state agency, and provider costs.
Marigold Health
Grant in 2020
Marigold Health operates a social network community platform designed to provide text-based group therapies for individuals facing mental health and substance use challenges. The platform facilitates anonymous support groups, allowing patients to engage with one another and receive guidance from coaches who have personal recovery experiences. By leveraging AI-augmented chat support, Marigold Health enhances the capacity of care teams while ensuring that patients receive personalized, stigma-free assistance. The company collaborates directly with treatment providers and managed care organizations within the Medicaid market to improve access to on-demand group therapies and foster a supportive community for recovery.
Limbix
Venture Round in 2020
Limbix is a prescription digital therapeutic company focused on developing innovative mental health treatments specifically for adolescents. The company offers a digital therapeutics platform designed to address the mental health challenges faced by young people, including depression and anxiety. Limbix's first product, SparkRx, enables licensed healthcare professionals to prescribe evidence-based, therapeutic interventions to improve the mental well-being of their patients. The diverse team at Limbix, consisting of clinicians, product designers, researchers, and engineers, combines clinical expertise with technological innovation to create effective digital solutions for adolescent mental health.
Marigold Health
Non Equity Assistance in 2019
Marigold Health operates a social network community platform designed to provide text-based group therapies for individuals facing mental health and substance use challenges. The platform facilitates anonymous support groups, allowing patients to engage with one another and receive guidance from coaches who have personal recovery experiences. By leveraging AI-augmented chat support, Marigold Health enhances the capacity of care teams while ensuring that patients receive personalized, stigma-free assistance. The company collaborates directly with treatment providers and managed care organizations within the Medicaid market to improve access to on-demand group therapies and foster a supportive community for recovery.
WorkingWell
Non Equity Assistance in 2019
WorkingWell is a research-based, feasibility-tested mobile app to help people with mental illness succeed at and sustain employment. WW users set and achieve goals, establish routines, learn to get along with others and develop coping skills contributing to workplace success and tenure. WW fills the gap between what we know about mental illness and employment and what we do about it, to enhance individual outcomes and reduce employer/employee assistance, a state agency, and provider costs.
Eleos Health
Non Equity Assistance in 2019
Eleos Health is a technology company that specializes in artificial intelligence-driven solutions for the behavioral health sector. It has developed a voice technology platform designed to enhance clinicians' decision-making by providing real-time insights during mental health sessions. This AI-powered system operates in the background, analyzing voice interactions and other data parameters to generate valuable information about patients. By leveraging this technology, Eleos Health aims to facilitate personalized care, ensuring that mental health professionals can deliver timely and cost-effective support tailored to individual needs.
Valera Health
Non Equity Assistance in 2018
Valera Health, established in 2015, operates a behavioral healthcare platform focused on delivering personalized mental health services to individuals with a range of conditions from mild to severe, including depression and schizophrenia. The company integrates digital technology and data science with traditional clinical services to enhance patient outcomes and address the needs of hard-to-reach populations. By providing a comprehensive approach that combines therapy, medication, and continuous connectivity with care teams, Valera Health aims to offer efficient mental healthcare solutions, particularly for employers seeking to improve access to mental health support for their employees.
BabyNoggin
Non Equity Assistance in 2018
BabyNoggin is a mental health screening application that empowers parents to self-screen their children's development using evidence-based tools. The application aligns with the recommendations of the American Academy of Pediatrics, allowing for effective tracking of developmental milestones. It facilitates the identification of children at risk for developmental delays and provides automatic scoring of screening results. Additionally, BabyNoggin supports the integration of these results into electronic medical records (EMR) systems, streamlining the referral process for children who require intervention services. By focusing on research-supported techniques, BabyNoggin aims to enhance parental involvement in monitoring their children's mental health and development.
HealthRhythms
Non Equity Assistance in 2017
HealthRhythms is a company that specializes in mental health assessment and treatment through an innovative platform that leverages deep machine learning and predictive analytics. Its solution focuses on real-time, objective monitoring of mental health conditions, providing continuous assessments and personalized digital interventions. By accurately measuring mental health status and anticipating clinical deterioration, HealthRhythms enables healthcare providers to identify and manage patients effectively. The platform enhances the care delivery experience for patients, health plans, payers, and research organizations by offering just-in-time interventions tailored to individual patient profiles. This groundbreaking approach aims to improve overall mental health outcomes and facilitate better management of behavioral health.
ReachMore
Grant in 2017
ReachMore application that treats anxiety created by trauma events.
Marigold Health
Grant in 2017
Marigold Health operates a social network community platform designed to provide text-based group therapies for individuals facing mental health and substance use challenges. The platform facilitates anonymous support groups, allowing patients to engage with one another and receive guidance from coaches who have personal recovery experiences. By leveraging AI-augmented chat support, Marigold Health enhances the capacity of care teams while ensuring that patients receive personalized, stigma-free assistance. The company collaborates directly with treatment providers and managed care organizations within the Medicaid market to improve access to on-demand group therapies and foster a supportive community for recovery.
Girls Health Champions
Grant in 2017
Girls Health Champions is an innovative, peer-to-peer education model where adolescent girls in India are trained to directly educate their peers about these important health topics, including nutrition, mental health, gender-based violence, menstruation, and reproductive health. Their peer educators ("Champions") are trained in focused curriculum which were created in partnership with leading pediatricians, psychiatrists, obstetricians and gynecologists, educational specialists, and school teachers in both the United States and India.
Yana
Seed Round in 2016
Yana is a developer of an emotional wellbeing chatbot that supports individuals dealing with anxiety and depression in their mental health journey. The chatbot utilizes principles of Cognitive-Behavioral Therapy to provide users with practical tools and strategies for improving their mental wellbeing. It offers an automated conversational agent that evaluates users' moods and engages in daily conversations, helping them understand the factors influencing their emotions. Additionally, Yana can connect users to crisis hotlines or mental health professionals, facilitating access to further therapeutic support. This approach allows users to address negative thoughts and behaviors at any time, promoting a proactive attitude towards mental health.
Spriteli
Grant in 2016
Spriteli is a digital health company which aims to reduce anxiety and elevate mood levels of our users through daily, 2 minute, video consultations. The video consultations are performed by a network of trained coaches. The calls consist of proprietary activities based on Mindfulness, Affirmation and CBT techniques. Initial beta results indicate we can improve outcomes and lower costs of traditional mental health delivery options. Currently collaborating with a major Boston Hospital.
Myndlift
Seed Round in 2015
Myndlift Ltd, founded in 2014 and based in Tel Aviv, Israel, develops innovative solutions for neurofeedback training, allowing users to connect with experienced practitioners from the comfort of their homes. The company integrates neurotechnology, behavioral psychology, and human care to enhance mental health treatment, making it accessible to tens of thousands of individuals through numerous mental health providers. Myndlift's technology measures brain wave activity and offers mind-controlled gamified exercises based on evidence-based techniques, primarily aimed at helping healthcare professionals assist patients with attention deficit hyperactivity disorder (ADHD) in improving their concentration and cognitive abilities.
Ginger
Seed Round in 2011
Ginger is a telemental health provider delivering evidence-based behavioral health coaching, therapy, and psychiatry from a smartphone. Ginger's on-demand system brings together behavioral health coaches, therapists, and psychiatrists, who work as a team to deliver personalized care, right through your smartphone. The app provides members with access to the support they need within seconds, 24/7, 365 days a year. Millions of people have access to Ginger through leading employers, health plans, and its network of partners.
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