MassChallenge

Xibus Systems develops and markets innovative microbiological analytics tools. These tools test consumable solutions for pathogens, allergens, and spoilage organisms in the food and beverage industry. The company is headquartered in Somerville, Massachusetts.

Embryoxite is a biotechnology company specializing in non-invasive diagnostic services for pre-implantation embryos in human-assisted reproduction. It operates a platform that combines artificial intelligence, metabolomics, embryo imaging, and clinical data to enhance embryo selection accuracy and improve patient outcomes for fertility clinics and reproductive specialists.

Aseptuva is an early-stage MedTech company based in Technopark Winterthur. It aims to combat Healthcare-Associated Infections (HAI) by developing medical devices for in-situ disinfection of various catheters, preventing infections at their source and potentially saving thousands of lives annually.

CNS Therapy is a spin-off from the University of North Carolina that develops mind-body therapy-based solutions and devices to alleviate chronic pain and related conditions. It combines operant behavioral therapy with a proprietary device called SET, Systolic Extinction Training, to enhance learning and reset the autonomic nervous system, with the aim of delivering long-lasting pain relief. The company tracks physiological parameters and uses the resulting data to optimize therapy, delivering an integrated program of psychological training and electrostimulation to help patients reduce or eliminate pain and return to daily activities.

HeroSupport is a medical device manufacturing company founded in 2019 and based in Veyrier, Geneva. The company specializes in creating medical immobilization devices designed to enhance patient comfort during clinical procedures. Its innovative technology transforms imaging and treatment tables into personalized support solutions, specifically catering to the needs of patients undergoing prone breast radiotherapy. This approach allows patients to benefit from tailored support, eliminating the need for them to adjust to the standard table. By improving patient comfort, HeroSupport enables healthcare providers to deliver more effective and cost-efficient cancer treatment.

Clean Valley CIC is a group of entrepreneurs, engineers, and environmental scientists with nature-inspired ideas for Canadian Innovation. Clean Valley provides nature-based solutions for the aquaculture industry and medical technology.

electronRx specializes in digital medicine solutions for chronic disease management. They develop personalized healthcare platforms that monitor cardiovascular health remotely, enabling patients to self-manage their conditions with clinical oversight.

Ember Sleep develops innovative medical devices for treating sleep apnea. Their platform offers a comfortable, effective, and non-invasive solution to improve sleep quality.

Curespec is a medical device company developing the Nephrospec, a non-invasive device designed to treat chronic kidney disease and hypertension. By preserving kidney function and delaying the need for dialysis, the technology supports clinicians in managing renal and hypertensive conditions and aims to reduce patient suffering.

KT Innovations is a provider of medical devices that aims to prevent costly & life threatening urinary tract and skin infections.

Taurus Vascular is a medical device company dedicated to enhancing long-term outcomes for patients suffering from aortic aneurysms. The company is focused on transforming the standard of care by developing innovative medical device technology aimed at addressing the complications associated with endoleaks. This technology is designed to facilitate accelerated shrinkage of the aneurysm sac following endovascular aortic aneurysm repair (EVAR). By improving the effectiveness of treatment, Taurus Vascular aims to significantly enhance patient outcomes in the healthcare sector.

SafeGuard Surgical is a medical device company focused on improving surgical outcomes and patient safety. It develops innovative, resorbable products designed to enhance colonic anastomotic healing and stability during advanced surgical procedures. These include a resorbable intraluminal stent graft and an extraluminal resorbable graft, along with anvil cap extension arms. By employing these products, SafeGuard aims to reduce surgical complications, lower healthcare costs, and minimize patient recovery time, ultimately preventing mortality and morbidity associated with surgery.

Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.

Founded in 2019, Blue Halo BioMedical specializes in manufacturing innovative catheter surgical devices for urologic patients. Based in Winter Park, Florida, the company aims to improve patient quality of life by offering proprietary internal male urologic catheters that enhance convenience and comfort.

HME Square is a healthcare technology company specializing in the development of innovative medical diagnostics and devices. Their primary product is a non-invasive glucose monitoring system, which combines photoacoustics, MEMS device technology, and deep learning algorithms to provide accurate and continuous blood glucose measurement without the need for blood sampling or needles. This technology aims to prevent chronic diseases by enabling users to monitor their sugar levels conveniently and effectively, promoting healthier lifestyles.

Unsmudgeable offers anti-smudge eyeglasses lens coating that is safe, productive, and convenient in a single application.

Lighthouse Tech specializes in developing smart assistive eyewear frames equipped with advanced radar sensing technology. These frames help individuals who are blind or visually impaired detect obstacles at the upper-body level, enhancing their mobility and reducing collision risks.

IC Innovations develops disruptive technology for respiration measurement and analysis. We are focused on lowering the barriers to access to advanced respiratory assessment, in fields such as sports and healthcare.

Code 1 Medical Devices provides medical solutions to prevent the aspiration of stomach contents into the lungs.

True Concepts Medical Technologies develops medical devices designed to reduce financial waste in healthcare while improving patient outcomes. The company creates cost-effective, manufacturable devices that address critical clinical needs, minimize human error, and improve diagnostic and treatment delivery. Its product development team applies broad experience in medical device design to support rapid development for clinician-inventors, startups, and manufacturers. The firm focuses on areas with high morbidity and mortality, delivering contaminant-free blood culture collection tools to improve sepsis diagnosis and support life-saving emergency care. Founded in 2017 and based in Centerville, Ohio, the company pursues solutions that can lower costs and enhance patient safety across the healthcare system.

Walk With Path specializes in developing wearable products that enhance mobility and provide therapeutic benefits for patients. The company's primary offering is a smart insole equipped with biofeedback and sensors, specifically designed to assist individuals with diabetes in improving balance and preventing foot ulcers. One of their key innovations, the Path Finder, is a medical device aimed at helping individuals with Parkinson's disease manage 'freezing of gait,' a condition where patients feel momentarily stuck. This product has shown efficacy through published evidence in Neurology. Walk With Path also offers data insights and analytics for both end users and healthcare professionals, making their products applicable for daily use and gait analysis in clinical and non-clinical settings.

DoubleLock Healthcare specializes in developing innovative medical devices aimed at reducing healthcare-associated infections. Their primary product is a novel intravenous (IV) port and syringe system designed to enhance sterility and safety. This system, which does not require alcohol swabs or caps, is engineered to decrease drug leakage, toxic vapors, and medication errors, thereby improving patient safety and lowering healthcare costs.

Founded in 2022 and headquartered in Houston, Texas, Bairitone Health develops innovative solutions for individuals with untreated obstructive sleep apnea. The company's core technology employs remote passive sensing and artificial intelligence to pinpoint structural collapses in the upper airway during sleep, enabling more informed treatment plans.

Helthy is a technology company that offers a browser extension, integrating with major online grocery retailers, to provide real-time food assessments and personalized recommendations for individuals with diabetes or prediabetes. The platform helps users make healthier choices during online grocery shopping by highlighting suitable alternatives and tracking dietary preferences, thereby supporting better blood sugar level management.

Intek Scientific develops multiplexed immunofluorescence imaging technology.This will empower clinicians and researchers to gain a deeper understanding of cancer and provide effective and customized therapeutic strategies to tackle even the most challenging cancers.

ZiO Health is a biotechnology company that develops pocket-sized devices featuring proprietary biosensor technology and machine learning algorithms. These devices enable real-time laboratory testing at the point-of-care, enhancing patient care by combining immediate results with individual patient profiles.

Pills2Me is a pharmacy delivery service focused on improving healthcare by removing barriers to medication access and adherence. The company operates a platform that allows users to order non-prescription pharmacy items and have them delivered, as well as facilitating the pickup and delivery of prescriptions from any pharmacy. This service is particularly beneficial for elderly and immunocompromised individuals, enabling them to maintain social distancing while ensuring access to essential medications. By streamlining the delivery process, Pills2Me aims to enhance the overall experience of obtaining necessary healthcare products.

Corveus Medical is a medical device company focused on innovative solutions for preventing heart failure. The company is developing a neuromodulation device designed to perform nerve ablation through a catheter-based approach. This minimally invasive technology aims to effectively target and access specific tissues, offering a novel treatment option for heart failure. By addressing both the clinical and economic challenges associated with this condition, Corveus Medical seeks to improve patient outcomes and enhance the overall management of heart failure.

ABBY is a new Personal EV for adults with reduced mobility, positioned as a long-overdue expansion play for the broken $9B wheelchair cartel

Women aged 20-45 cannot get screened for breast cancer because existing solutions are unreliable. However, 81% want to. At The Blue Box, we have built a pain-free, low-cost, sensitive, radiation-free device to detect breast cancer in urine with a sensitivity of 83%. In 2024, we’ll launch into the market, bringing The Blue Box to private gynecology clinics with a Diagnostics-as-a-Service subscription model, and a pay-per-test revenue stream that we’ll share with doctors.

XN Health is a medical device company founded in 2021 and based in Texas, USA. The company focuses on developing innovative healthcare solutions to assist mechanically ventilated patients in weaning off ventilators more efficiently. Its primary product utilizes phrenic nerve stimulation to induce diaphragm contractions, thereby mitigating the risks of diaphragm dysfunction associated with prolonged mechanical ventilation. By enhancing the weaning process, XN Health aims to improve patient outcomes and facilitate recovery in critical care settings.

MZP Tech is a medical device company focused on point-of-care coagulation analysis. It develops diagnostic methodologies in hemostasis to support the management of bleeding and thrombotic risk. The company’s coagulation diagnostic device analyzes a small blood sample in minutes using a disposable micro-machined chip and a portable sensing system that measures blood viscosity, enabling early screening for cardiovascular-related diseases and clotting disorders.

Astron Medtech specializes in developing disposable, minimally invasive surgical devices for tendon repair. Their innovative solutions aim to reduce recovery time by half, from six months to four.

SensArs specializes in medical equipment manufacturing, focusing on neuromodulation solutions. Its flagship product, SENSY, is an innovative healthcare technology system designed to restore natural sensations to the feet for patients who have undergone amputations or suffer from nerve damage due to diabetic neuropathy.

myBiometry is developing a platform to monitor/manage patients with chronic disease using biomarker data from proprietary sensors and ML to identify patients at risk of treatment failure. Our initial focus is asthma where treatment failure occurs over 46% of the time (11.5M US patients, $80 billion). We are developing a single use, disposable sensor and device to track a biomarker of inflammation in breath. The data determines changes in adherence, treatment response, and risk of attack.

SafetySit is a company focused on developing assistive therapeutic medical devices aimed at supporting disabled or recovering patients who struggle with core muscle strength. Its main product is a mobile backrest designed to facilitate the sitting posture of these individuals. By enabling clinicians to treat patients more effectively, SafetySit's innovation enhances the early mobilization process in recovery, allowing healthcare providers to eliminate the need for manual support during therapy sessions. This approach not only aids in patient rehabilitation but also improves the overall efficiency of clinical care.

Newton Tech specializes in developing AI-based precision rehabilitation platforms. Their flagship product, Mobi, is designed to aid stroke patients' recovery by providing individualized insights and real-time fall detection and prevention.

Astellar Labs specializes in non-invasive blood glucose monitoring technology. Their innovative solution enables users to measure blood sugar levels without the need for finger pricks or frequent device replacements, enhancing comfort and reducing costs. The company's technology employs artificial intelligence to track glucose levels over time, predict trends, and issue early warnings, empowering patients to proactively manage their health.

N95 Mask Preserve is a PPE protection device developed for healthcare workers on the COVID-19 frontlines. It is built with antimicrobial, antifungal, mold, and mildew inhibiting technology. It protects masks from damage and contamination.

WestFace Medical is a medical device company focused on enhancing vascular access procedures through its innovative product, SingleStick™. This device employs patented needle tip imaging using optical coherence tomography (OCT) to provide real-time visualization of the needle's trajectory. SingleStick™ consists of a handheld imaging adapter that can be attached to any hollow bore needle, along with an OCT image processor. The adapter introduces an optical fiber into the needle, allowing clinicians to view anatomical markers in real-time as they perform vascular access. This technology aims to redefine the standard of care in medical procedures, ultimately improving clinical outcomes, reducing costs, and increasing patient satisfaction. By facilitating traditional vascular access techniques with advanced imaging capabilities, WestFace Medical addresses significant challenges in pediatric care and beyond.

INIA Biosciences is a developer of innovative medical devices that leverage sound wave technology to create non-invasive, home-administered systems for managing chronic inflammatory diseases. The company focuses on a closed-loop monitoring system designed to treat and prevent organ failure by integrating biomarker monitoring with an ultrasound stimulator. This approach aims to reduce inflammation linked to transplant rejection rates and minimize reliance on immunosuppressant drugs. By providing novel diagnostic sensing capabilities, INIA Biosciences enables physicians to better manage chronic diseases and improve patient outcomes.

NemoCare develops a comprehensive patient monitoring system using wireless wearable sensors, analytics, and big data. Its primary focus is on affordable, continuous monitoring for newborns in hospitals and at home, aiming to improve maternal and neonatal care.

Vaccine Systems develops automated equipment to simplify vaccine reconstitution, enhancing accessibility, efficiency, and safety in vaccination campaigns worldwide. By streamlining preparation processes, they aim to reduce waste (currently up to 70% according to WHO) and ensure optimal vaccine allocation.

Thermy is a healthcare technology company focused on addressing late-stage breast cancer diagnoses, particularly in Mexico, Latin America, and the Caribbean. The company has developed an AI-powered infrared imaging device that offers a comfortable and radiation-free alternative to traditional mammograms, promoting early detection and potentially improving survival rates. Thermy's platform is designed to be accessible on both mobile and desktop devices, allowing doctors to utilize infrared cameras to assess patients' likelihood of having breast cancer. By targeting underserved communities, Thermy aims to reduce mortality rates associated with delayed breast cancer detection.

MoviWear is a company specializing in medical AI and remote monitoring solutions, with a focus on enhancing the safety and health of seniors. Its flagship platform, MoviWearMED, enables real-time health monitoring through proprietary 5G IoT NurtureWatch wearables. This technology allows for continuous tracking of vital signs, including heart rate, temperature, blood pressure, and oxygen levels, as well as fall detection, whether individuals are at home, in retirement communities, or on the move. Designed to respond to the critical need for 24/7 health monitoring outside of hospital settings, MoviWearMED provides instant alerts when there are significant changes in a patient's condition. Since its establishment in 2017, MoviWear has collaborated with various health and telecommunications companies across North America, Europe, and Israel, aiming to prevent health crises and improve quality of life for seniors.

GiveMove is a healthcare technology company specializing in the manufacture of assistive mobility devices for individuals with motor disabilities. The company offers a range of innovative, practical, and customized solutions, including its Bipmov suite of static and motorized standers for both adults and children, incorporating IoT technology.

Manus Robotics is a developer of advanced health and wellness devices aimed at promoting independent and healthy living. The company specializes in a wearable robot that offers intelligent daily living assistance to individuals with disabilities. In addition to facilitating daily activities, this device collects and analyzes muscle data from patients, which is crucial for rehabilitation. By focusing on these innovative solutions, Manus Robotics helps individuals with disabilities improve their quality of life and regain their independence.

Insu Health Design develops a personal-use medication storage system designed to keep medicines, including insulin, cool for extended periods. The device combines a thermoelectric cooler, vacuum flask, and fluid loop, and includes solar panels and a portable, battery-powered cooler with multiple charging options to protect medications during travel, power outages, or disasters. The company was co-founded in 2018 in San Juan, Puerto Rico by Mason Lucich and Doris Candelaria.

LucyDx is dedicated to preventing blindness in diabetics by focusing on early detection of retinal eye diseases. The company has developed a wearable, compact, and non-invasive diagnostic device that utilizes electroretinogram (ERG) technology to monitor eye health. This automatic system allows diabetics to detect conditions such as diabetic retinopathy at an early stage, enabling timely intervention and treatment by medical professionals. By facilitating early diagnosis and ongoing tracking of eye damage, LucyDx aims to preserve eyesight and improve the quality of life for individuals at risk of vision loss due to diabetes.

Through the experience of 15-year skin optics research, we developed optical modules that work in conjunction with sophisicated algorithms to quantify various skin contents such as hemoglobin, bilirubin, skin collagen, skin oxidative stress, blood glucose variation, and etc. In contrast to the market available wearable optical modules that can only measure heart beat rate, our wearable module design provides much more information for personal health monitoring and thus could have multitude application scenarios with great marketing potential.

FormaPath develops automated laboratory tools that streamline tissue biopsy handling and lymph node isolation for cancer diagnostics. Its hands‑free system prepares tissue samples for pathology, while its instrument separates lymph nodes from adipose tissue, improving diagnostic accuracy and efficiency in pathology labs and cancer research centers.

Adventus Robotics specializes in developing self-driving power wheelchairs, leveraging artificial intelligence and autonomous technology. Their products are designed to safely and accurately navigate diverse environments, enhancing mobility for individuals with severe physical disabilities and hospital patients. Adventus offers a solution that can be mounted onto existing manually-operated powered wheelchairs, ensuring accessibility and improving users' well-being.

Yengii Biosciences develops the Galet smartphone microscope for detecting infectious illnesses such as malaria, sleeping sickness, and tuberculosis. The Galet platform is intended to do very complicated blood film analysis in a simple, portable point-of-care tool, which is now limited to high-end laboratories. Making such blood film analysis more available would allow for the early diagnosis of the most serious health concerns, such as malaria, and will save lives.

munevo is a technology company based in Nuremberg, Germany, founded in 2011. It develops munevo DRIVE, a smart glass application that translates the user’s head movements into digital signals to operate electric wheelchairs hands-free. The solution enables independent mobility for people with mobility impairments both indoors and outdoors. In addition to the core software, munevo offers adaptors and accessories to support wheelchair integration. The company focuses on applying smart glass technology to assistive devices, with the aim of enhancing autonomy and daily living for users who require mobility assistance.

Vironix Health develops machine-learned surveillance technologies for real-time remote monitoring and early detection of health deterioration from COVID-19, influenza, COPD, and other respiratory illnesses. Its hardware-agnostic APIs are embedded in patient, provider, and employer applications to support remote monitoring and wellness. The company also offers a virtual care management platform that enables healthcare providers to monitor patients at home, delivering remote monitoring, remote therapeutic monitoring, chronic care management, primary care management, and complex chronic care management to improve outcomes and reduce costs.

Neurava specializes in developing wearable diagnostic devices for epilepsy patients. Their products monitor health metrics, alert users and healthcare providers to seizures and cardiorespiratory dysfunctions, enabling timely intervention and improved treatment outcomes.

NeuroGeneces develops an artificial intelligence driven brain health assessment platform to detect early signs of neurodegeneration before cognitive symptoms appear. Its Brain Age test analyzes patient EEG data collected via a sleep headband and ML software, benchmarking against a proprietary normative database to provide objective measures of brain function. The platform enables healthcare practitioners to identify at-risk individuals and guide preventive interventions through early behavioral strategies, offering more comprehensive insights than traditional biomarkers.

Diamante is a company based in Verona, Italy, that specializes in the development and manufacturing of diagnostic devices for autoimmune diseases, utilizing innovative nanomaterials. Founded in 2016, the company leverages plants as bioreactors to produce nanoparticles derived from modified plant viruses. This approach allows Diamante to create advanced tools for diagnosing and potentially treating autoimmune conditions, focusing on sustainable and efficient production methods. Through its research and development efforts, Diamante aims to contribute significantly to the field of autoimmune disease therapy.

Gelatex is a materials technology company based in Estonia, founded in 2016 and incorporated in the UK in 2019. The company specializes in producing bio-based nanofibers using a patented technology that allows for large-scale production at significantly lower costs. Gelatex's nanofibers are derived from gelatin sourced from low-value waste in the meat and leather industries, ensuring that its products are environmentally friendly and made from natural, non-toxic substances. Initially focused on developing eco-friendly leather-like textiles, the company recognized the broader applications of its technology during the COVID-19 pandemic, leading to a strategic pivot. Gelatex's innovative solutions have potential applications in various fields, including tissue engineering, cultured meat production, bio-based filtration, energy storage, and wound care.

Paragit Solutions specializes in developing innovative systems for remote patient monitoring and data-driven clinical management of movement disorders, particularly Parkinson's disease. Central to their offerings is the Paragit Sleeve, which employs a patented sEMG (electromyography) technology to gather precise data on muscle activation, movement, and grip force during patients' daily activities. Paragit provides two main software suites for data interpretation: the PD Monitor, tailored for caregivers, which visualizes key motor symptoms like rigidity and tremors to enhance treatment optimization and facilitate telemedicine; and the MD Lab, designed for decentralized clinical trials across various movement disorders. MD Lab enables researchers to analyze over 20 metrics related to disease severity, track trends, and compare groups consistently, with a robust API that supports extensive data access for further analysis. Through these technologies, Paragit aims to improve the management and understanding of movement disorders, enhancing patient care and clinical research.

BestHealth4U specializes in developing advanced adhesive technologies for medical applications. Their innovative solutions aim to prevent skin injuries, enhance healing, and improve overall patient health by transforming how bandages, dressings, and medical devices adhere to the skin.

Advanced Interactive Response Systems - AIRS in Newaygo, Michigan, provides oxygen supply monitoring systems for hospitals, homes, and other remote areas. With this system, the patient is able to safely monitor air flow for oxygen tanks. It has an alarm feature that sends updates via text messaging or Bluetooth™. The AIRS devices are also wirelessly linked to each other using a secure and robust mesh networking protocol. Hospitals and medical personnel will greatly benefit from this state-of-the-art monitoring system.

Aidplex is a MedTech startup focused on orthopedics, developing patient-centered wearable devices and monitoring solutions that enable real-time tracking of treatment progress. The company aims to transform orthopedic care by integrating biometric sensors into wearables to provide 24/7 monitoring and comprehensive data on patient health improvements during scoliosis and fracture treatments. Designed for physicians, Aidplex's devices emphasize effectiveness and comfort, enabling clinicians to monitor patient status remotely and make informed treatment decisions. The company operates in the United States and Greece.

Criam is a Portuguese biotechnology company based in Braga that develops portable diagnostic technology for blood typing and infectious disease detection. Its stand-alone platform does not require electricity or laboratory infrastructure, enabling rapid testing at the point of care. A single reader can perform multiple tests using cartridges and computer vision algorithms to detect a broad range of diseases, including HIV, with real-time data to support clinical decisions. The system leverages lab-on-a-chip concepts and biomarker detection algorithms to deliver fast, user-friendly, and cost-effective diagnostics in diverse settings, including remote environments and emergency care.

BioEclosion is a biotechnology company specializing in the development of user-friendly, rapid diagnostic tools. Its core technology, Celifast, is a non-invasive method for detecting celiac disease, validated and patented. The company aims to expand this platform to other emerging diseases, using molecular biomarkers for swift identification. BioEclosion's device comprises a single-use cartridge tailored to each application and a portable, battery-operated reader, making it versatile for human and veterinary health, as well as food and environmental safety.

Kobara Medical specializes in developing innovative medical therapeutic devices aimed at addressing heart failure with preserved ejection fraction (HFpEF), a condition where the heart struggles to fill its main pumping chamber effectively. This condition affects over three million people and is growing. The company's unique, minimally invasive device leverages the heart's transverse pericardial sinus for neuromodulation therapies, providing an alternative to traditional cardiac rhythm management methods that often require multiple leads or invasive procedures. By utilizing this approach, Kobara Medical offers a novel solution that combines multiple leads into one, enabling multi-chamber pacing from outside the blood vessels.

Babylat develops a compact, automated medical device designed for protein enrichment of human milk. This tabletop device enables on-site concentration of the protein fraction in hospitals, ensuring newborn babies receive sufficient protein.

Diagnoly develops an AI-powered medical device that analyzes fetal ultrasound examinations in real-time, assisting doctors in detecting complex fetal pathologies.

4Blind develops assistive technology for individuals with visual impairments. Their innovative tools enhance communication and accessibility, facilitating education, employment, social integration, and independent living.

munevo is a technology company based in Nuremberg, Germany, founded in 2011. It develops munevo DRIVE, a smart glass application that translates the user’s head movements into digital signals to operate electric wheelchairs hands-free. The solution enables independent mobility for people with mobility impairments both indoors and outdoors. In addition to the core software, munevo offers adaptors and accessories to support wheelchair integration. The company focuses on applying smart glass technology to assistive devices, with the aim of enhancing autonomy and daily living for users who require mobility assistance.

SlitLED Israel is a 3D & digital, mobile eye-examination system operating remotely and in real-time.

VenoVision develops a contactless, AI-driven cardiopulmonary monitoring platform that uses thermal imaging and machine learning to non-invasively assess hemodynamic status. This helps healthcare professionals detect patient deterioration earlier, improve care, reduce ICU admissions, and lower hospital readmissions.

V-Opt is an eye-care telemedicine company, integrating the key examination devices from the ophthalmologist clinic into a single, autonomous unit to be widely deployed in the retail & pharmacy chains. Leveraging advanced AI and ML algorithms, screening & follow-up visits will be replaced with <7min self-test, including fundus, lens, IOP, and much more, and shared with by the person’s own ophthalmologist. V-Opt will truly enable transforming ophthalmology modality from treatment to prevention.

IMMA Health is a pioneering company focused on transforming the fertility journey for women. It offers a remote, self-operated device that enables women to perform intravaginal ultrasound scans at home, assisted by AI-powered image analysis. This innovative solution reduces the need for frequent clinic visits, providing a more comfortable, safe, and intimate experience for users.

Pacify Medical Technologies is a medical device startup focused on wound care, with patent-protected technology that sprays skin tissue onto wounds to promote fast recovery. The company develops devices for skin grafting and tissue application, including portable systems for uniform grafting and spray-based wound coverage, enabling healthcare professionals to improve wound healing, shorten procedures, reduce hospital stays, and support faster patient recovery through efficient wound care solutions.

Travaxy Ltd., established in 2016 and based in Ramat Yishai, Israel, specializes in operating an online travel booking platform catering to individuals with disabilities or mobility issues, as well as senior travelers requiring assistance. The company offers a range of services including hotel accommodations, flights, wheelchair rentals, and medical solutions tailored to these specific needs. Travaxy aims to facilitate accessible holiday planning and bookings for its target customers by recognizing their requirements during the booking process and providing relevant information about accessible attractions and services at their destinations.

Founded in 2017, Serenno Medical specializes in designing and manufacturing medical devices for hospitalized patients. Its flagship product is the Sentinel device, which automatically measures and monitors urine output, aiding in early detection of kidney damage.

Liposphere develops and manufactures AqueousTech, a proprietary water-based platform technology for lubricants. Its flagship product, AqueousJoint, is an injectable designed to treat knee osteoarthritis by forming a durable protective layer on joint surfaces, reducing friction and wear more effectively than conventional substances.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, specializing in respiratory health management through innovative sensor-based solutions. Founded in 2016, the company has developed a wearable device that provides real-time insights into breathing patterns, sounds, and speed. This device is equipped with clinical-grade biosensors and smart software, allowing for continuous monitoring of respiratory conditions such as asthma and chronic obstructive pulmonary disease. By connecting to a mobile application, Strados enables users and healthcare providers to access and analyze respiratory data, facilitating informed health decisions and remote patient monitoring.

Zibrio specializes in advanced balance diagnostics. It leverages NASA technology originally used on astronauts, along with machine learning, to measure subtle changes in balance. Incorporated in 2017, Zibrio aims to empower users to manage their health proactively by providing insights into their balance profiles.

Mosaic health data provides medical records of complete data of a patient's health across the continuum of care

MindMics is an emerging wearable company developing an in-ear, sound-based health monitoring platform that uses earbuds and hearing aids to measure biometrics in real time, including heartbeat, breathing, circadian rhythms, and body temperature, with the goal of supporting mental performance, focus, mindfulness, and overall well-being.

4Blind develops assistive technology for individuals with visual impairments. Their innovative tools enhance communication and accessibility, facilitating education, employment, social integration, and independent living.

Kinto.Care is an online platform designed to enhance communication and support for caregivers, particularly those caring for loved ones with dementia. The platform offers user-generated content and digital tools that facilitate care team collaboration, medication management, and tracking of health data. By providing practical advice, care planning, and group learning opportunities, Kinto.Care aims to empower family members to effectively coordinate care and manage their loved ones' medical needs through a unified interface.

Haptic (WearWorks), a B2B SaaS company creating a universal language through touch. We have patented the haptic navigation technology, which made history. Haptic guided the first runner who is blind in the NYC Marathon with their HapticNav app.  Haptic is redefining inclusive mobility. Our patented technology uses tactile communication to guide users through subtle vibrations, offering a seamless, screen-free, ears-free experience. This empowers all users—especially those with visual impairments—to navigate independently. Haptic is revolutionizing inclusive technology. Our patented HapticNav tool transforms how we navigate the world, offering a hands-free, eyes-free experience through the power of touch. It empowers thousands, especially those with visual impairments, to reclaim their independence and live screen-free.

Limula develops an automated cell therapy manufacturing platform that combines bioreactor and centrifuge capabilities into a single device, supported by hardware, software, and consumables. The platform enables scalable, decentralized production of cell therapies by bringing manufacturing closer to patients and supporting multiple cell types. It automates complex processing steps within a closed, modular system, allowing biotech and pharmaceutical companies to move from open, manual methods to automated operations, improving efficiency, safety, and accessibility of personalized treatments.

Starling Medical is focused on creating a remote patient monitoring platform that facilitates at-home urine diagnostics, aiming to integrate seamlessly into everyday bathroom routines. The company designs healthcare devices that utilize mass spectroscopy-based sensors for continuous monitoring and early detection of health issues through urine analysis. By tracking changes in urine composition over time, Starling Medical's technology enables timely intervention for patients and healthcare providers, potentially preventing complications and reducing the need for hospitalizations. The organization is dedicated to developing predictive technology that enhances early detection of chronic health concerns, ultimately improving patient outcomes.

Readily3D is a Lausanne, Switzerland-based company that commercializes volumetric tomographic 3D printers and bioprinting solutions. A spin-off from École Polytechnique Fédérale de Lausanne, it was founded in 2020 after researchers developed tomographic printing methods starting in 2017. The company's printers enable centimeter-scale, tomographic 3D printing of cells and biomaterials with optical resolution below 100 micrometers, and are paired with software that imports design files, optimizes print parameters, and minimizes cell stress and light exposure. This technology supports rapid prototyping of living tissue constructs and statistically meaningful biological models for life sciences research.

PREEMIEr Diagnostics is a healthcare company focused on improving the health outcomes of premature infants, specifically in the prevention of retinopathy of prematurity. The company has developed a diagnostic device that accurately measures blood glucose levels in these vulnerable patients. This technology assists healthcare providers in identifying infants who require adjustments to their glucose levels, facilitating early detection of potential health issues. By enhancing the ability of medical professionals to monitor and manage the health of premature infants, PREEMIEr Diagnostics contributes to better clinical outcomes and overall infant care.

myBiometry is developing a platform to monitor/manage patients with chronic disease using biomarker data from proprietary sensors and ML to identify patients at risk of treatment failure. Our initial focus is asthma where treatment failure occurs over 46% of the time (11.5M US patients, $80 billion). We are developing a single use, disposable sensor and device to track a biomarker of inflammation in breath. The data determines changes in adherence, treatment response, and risk of attack.

Code 1 Medical Devices provides medical solutions to prevent the aspiration of stomach contents into the lungs.

Healium is a technology company that develops mental fitness tools and immersive, bio-data-driven experiences to support self-management of anxiety, sleep issues, burnout, and overall well-being. The platform links real-time biometric data from wearables such as heart rate and brain activity via EEG headbands to personalized video or VR assets, producing reactive media escapes controlled by the user’s physiology. By integrating wearable devices and sensors, Healium delivers data-driven content that adapts to the user in real time, aiming to reduce anxiety, improve mood, and build resilience for individuals and organizations. Peer-reviewed studies have reported rapid mood benefits and anxiety reduction in as little as four minutes.

Lainomedical is a company that develops innovative respiratory devices aimed at delivering medication through inhalation, specifically targeting the treatment of asthma, cystic fibrosis, and other respiratory disorders. The company focuses on designing and manufacturing nebulizers that enhance treatment efficacy while minimizing medication errors. Its patented delivery technology offers a unique solution for administering medications to the nose and throat area, complementing its portfolio of over-the-counter (OTC) and pharmaceutical products. Lainomedical's devices are engineered for ease of use, eliminating the need for cleaning or disinfection, which helps both healthcare providers and patients achieve optimal treatment outcomes and improve overall quality of life.

Tremedics develops bioresorbable technology for congenital heart disease patients with congenital heart disease need devices that resorb within their bodies as they grow. Their technology utilises a minimally invasive surgery procedure for stent delivery and permits vessel growth as the stent resorbs in the body.

Equine Smartbit, LLC is a company based in Saint Louis, Missouri, that specializes in the design and manufacture of innovative health monitoring devices for horses. Founded in 2016, the company has developed the SmartBit, a device equipped with biometric sensors that allows horse owners, trainers, and veterinarians to monitor and analyze the real-time wellness, health, and performance of horses. The SmartBit measures vital signs such as temperature, heart rate, and blood oxygen saturation, providing critical data that helps in assessing a horse's physical condition during training and competition. The device alerts users when a horse's health status may be compromised, thus facilitating timely interventions. In addition to its hardware, Equine Smartbit offers software tools that enhance the analysis of the collected biometric data, supporting informed decision-making in equine care.

ChondroNest is focused on developing medical technologies aimed at cartilage reconstruction, specifically targeting conditions such as Osteochondritis and Osteoarthrosis. The company is creating a device made from modified biopolymers intended for in vivo use, facilitating easier and more effective reconstruction surgeries for surgeons. ChondroNest plans to conduct preclinical tests on animal models before moving on to human trials. Following these initial trials, the company intends to license its product to major MedTech companies for sales and marketing purposes, while maintaining control over the production of its ChondroNest™ pastes.

Founded in 2019, Solenic Medical specializes in the development of a non-invasive medical device that uses alternating magnetic fields to eradicate biofilm on metallic implants. Its technology aims to address complications arising from surgeries like knee and hip replacements, as well as trauma-related implants.

EarlySight, a Lausanne-based medical device company, develops technology to detect and treat eye diseases at an early stage. Its flagship work includes a fundus camera that images the retina with high detail by combining eye illumination with real time ocular aberration correction. The company also leverages cellular level imaging and transscleral illumination to monitor day to day treatment effects in a non invasive manner, enabling eye specialists to visualize the morphology of retinal cells. Founded in 2016, EarlySight aims to bring its imaging technology to clinics to improve early diagnosis and treatment of ocular conditions.

NeuroRescue develops and markets a non-invasive medical device that enables emergency responders to initiate therapeutic hypothermia in the field using off-the-shelf cold packs and to maintain monitored, continuous cooling through hospital care. The system targets stroke, brain injury, and post-cardiac arrest patients by improving neurological outcomes and providing a seamless handoff from field to definitive care. The company is headquartered in Lafayette, Louisiana.

Walk With Path specializes in developing wearable products that enhance mobility and provide therapeutic benefits for patients. The company's primary offering is a smart insole equipped with biofeedback and sensors, specifically designed to assist individuals with diabetes in improving balance and preventing foot ulcers. One of their key innovations, the Path Finder, is a medical device aimed at helping individuals with Parkinson's disease manage 'freezing of gait,' a condition where patients feel momentarily stuck. This product has shown efficacy through published evidence in Neurology. Walk With Path also offers data insights and analytics for both end users and healthcare professionals, making their products applicable for daily use and gait analysis in clinical and non-clinical settings.