MassChallenge

HeroSupport is a medical device manufacturing company that transforms imaging and/or treatment tables into personalized solutions. The company was founded in 2019 and is headquartered in Veyrier, Geneva.

Clean Valley CIC is a group of entrepreneurs, engineers, and environmental scientists with nature-inspired ideas for Canadian Innovation. Clean Valley provides nature-based solutions for the aquaculture industry and medical technology.

Walk With Path develops wearable products aimed at improving mobility and health for patients, particularly those affected by diabetes and movement disorders. The company’s flagship offering is a smart insole equipped with biofeedback technology and sensors, designed to enhance balance and prevent complications such as foot ulcers in diabetic patients. Additionally, Walk With Path has introduced Path Finder, a specialized shoe designed for individuals with Parkinson's disease to alleviate the 'freezing of gait' phenomenon, which can leave users feeling immobilized. Path Finder is recognized as a medical device with supporting evidence published in Neurology. The company's products not only provide therapeutic benefits but also offer data insights and analytics for both end users and healthcare professionals, facilitating gait analysis and promoting better mobility in various populations.

Women aged 20-45 cannot get screened for breast cancer because existing solutions are unreliable. However, 81% want to. At The Blue Box, we have built a pain-free, low-cost, sensitive, radiation-free device to detect breast cancer in urine with a sensitivity of 83%. In 2024, we’ll launch into the market, bringing The Blue Box to private gynecology clinics with a Diagnostics-as-a-Service subscription model, and a pay-per-test revenue stream that we’ll share with doctors.

MZP Tech is a company focused on point-of-care coagulation analysis, aiming to improve healthcare delivery through innovative diagnostic methodologies. They develop medical devices capable of rapidly analyzing blood samples, utilizing a disposable micro-machined chip and a portable embedded sensing system. This technology allows for the analysis of a single drop of blood within minutes, measuring blood viscosity. By doing so, MZP Tech enables healthcare professionals to conduct early-stage screenings for various conditions, including cardiovascular diseases, blood-clotting disorders, and hyperviscosity-related issues. Their advancements in hemostasis contribute to better management of bleeding and thrombotic risks, enhancing patient care.

Unsmudgeable offers anti-smudge eyeglasses lens coating that is safe, productive, and convenient in a single application.

Bairitone Health builds solutions for people with untreated obstructive sleep apnea. Founded in 2022, the company is headquartered in Houston, Texas.

Astron Medtech is a medical technology company focused on improving patient outcomes in tendon repair. The company develops disposable minimally invasive surgical devices that significantly reduce recovery time from six months to four months. By utilizing less invasive and sustainable surgical techniques, Astron Medtech aims to enhance the efficiency of surgical services while providing better options for patients undergoing tendon repair procedures.

Ember Sleep is a company focused on improving sleep quality through its innovative sleep apnea treatment platform. The platform features medical devices designed to be more comfortable, effective, and non-invasive for the treatment of sleep apnea. By providing a novel approach to open the airway, Ember Sleep aims to enhance the well-being of patients, enabling them to feel more rested while assisting healthcare professionals in delivering better health outcomes.

HME Square is a digital healthcare company focused on developing medical diagnostics and devices that utilize innovative technology for health monitoring. The firm specializes in creating non-invasive glucose monitoring systems designed to measure health data accurately and continuously without the need for blood sampling or needles. By integrating photoacoustics, MEMS device technology, and deep learning into a cohesive digital data platform, HME Square aims to prevent chronic diseases and empower individuals to manage their glucose levels effectively, thereby promoting healthier lifestyles.

True Concepts Medical Technologies is a medical company that focuses on reducing financial waste in the healthcare system while improving patient outcomes. It delivers innovative and manufacturable solutions based on clinical experience. The company's flagship series of novel, cost-effective, technologies developed with the potential to save billions of dollars annually. True Concepts Medical Technologies' innovative devices deliver safe and effective solutions that reduce errors, provide consistent clinical delivery, and reduce costs. The company is creating these devices with the product development horsepower of Pixel and Timber a product design and development team that has developed dozens of innovative medical devices for clinician-inventors, startups, and manufacturers alike. True Concepts Medical Technologies was founded in 2017 and is headquartered in Centerville, Ohio, USA.

Lighthouse Tech specializes in designing smart eyewear frames aimed at individuals with vision impairment, blindness, and spatial perceptual disorders. Their innovative product detects obstacles above the waist and alerts users through soft haptic vibrations. The eyewear is crafted to resemble conventional frames or sunglasses, ensuring that users do not compromise on style while benefiting from enhanced safety and mobility. By combining functionality with fashion, Lighthouse Tech promotes independent outdoor navigation, ultimately fostering a greater sense of self-sufficiency and well-being for its customers.

Corveus Medical is developing a new way to prevent heart failure. It is a neuromodulation device that can uniquely reach tissues, unlocking a new field of heart failure treatment. Its goal is to develop a device that safely accesses tissue, providing consistent results.

SensArs is a medical equipment manufacturing company specializing in neuromodulation technology aimed at treating diabetic neuropathy. The company has developed an innovative implantable neurostimulator electrode designed to restore sensory feedback by delivering precise electrical impulses to the nerve fibers that transmit pain signals. This technology not only assists healthcare providers in enhancing patient functionality but also offers a long-term solution for pain management. SensArs' flagship system, SENSY, is particularly beneficial for patients with amputations or nerve damage, as it helps to restore natural sensations in their feet.

myBiometry is developing a platform to monitor/manage patients with chronic disease using biomarker data from proprietary sensors and ML to identify patients at risk of treatment failure. Our initial focus is asthma where treatment failure occurs over 46% of the time (11.5M US patients, $80 billion). We are developing a single use, disposable sensor and device to track a biomarker of inflammation in breath. The data determines changes in adherence, treatment response, and risk of attack.

N95 Mask Preserve is a PPE protection device developed for healthcare workers on the COVID-19 frontlines. It is built with antimicrobial, antifungal, mold, and mildew inhibiting technology. It protects masks from damage and contamination.

AMF Medical is focused on developing Sigi, an innovative patch pump designed to administer insulin with exceptional ease of use. This novel device is intended for seamless integration into closed loop systems, compatible with third-party Continuous Glucose Monitoring products and dose-calculating algorithms. The company's mission is to alleviate the therapy burden faced by individuals with diabetes, ultimately aiming to enhance their quality of life. AMF Medical was established in early 2021 as a spin-off from Advanced Microfluidics, which specializes in high-end lab equipment components that utilize related technologies.

SafetySit develops an assistive therapeutic medical device to support disabled or recovering patients to sit in an upright position.

Astellar Labs develops a non-invasive diagnostic technology that allows people to measure blood glucose without having to prick their fingers or wear a device that needs to be regularly swapped out, thus eliminating discomfort while also saving money.

GiveMove is a assistive technology manufacturer for people with motor disabilities. We are mobility experts engaged in providing innovative, practical & customized solutions to improve the well-being of our clients and their surroundings. We developed Bipmov complete suite of static & motorized standers for adults & children, which includes IoT Technology. Follow us on instagram, twitter or facebook as @givemovear!

MoviWear is a technology company that specializes in medical AI and remote monitoring solutions, primarily through its platform MoviWearMED. This platform is designed to monitor patients' vital signs in real-time, whether they are at home, in retirement facilities, or on the go. By utilizing proprietary 5G IoT NurtureWatch wearables, MoviWear can detect critical changes in health indicators such as heart rate, temperature, blood pressure, and oxygen levels, as well as alerting caregivers in case of falls. The company addresses the increasing demand for continuous health monitoring outside of traditional hospital settings, particularly for seniors. Founded in 2017, MoviWear aims to enhance patient safety and prevent health emergencies, drawing inspiration from a personal family experience. Its clientele includes health and telecommunications companies across North America, Europe, and Israel.

Manus Robotics is focused on developing a smart health and wellness device aimed at promoting independent and healthy living. The company offers a wearable robot that assists individuals with disabilities in their daily activities, providing intelligent support to enhance their quality of life. In addition to daily living assistance, the device collects and analyzes muscle data from patients, facilitating rehabilitation efforts and helping users regain independence.

Insu Health Design, founded in 2018 in San Juan, Puerto Rico by Mason Lucich and Doris Candelaria, specializes in creating a personal-use system for the safe storage of medications. Their innovative storage solution combines a thermoelectric cooler, vacuum flask, and fluid loop to maintain optimal temperatures for medicines, particularly bio-medicines like insulin. The product is equipped with affordable solar panels and a portable, battery-powered cooler featuring multiple charging options. This design allows patients to safeguard their health by ensuring that their medications remain viable during travel, power outages, or emergency situations.

Vironix Health specializes in developing advanced machine-learned surveillance technologies that enable real-time, remote monitoring and detection of health deterioration related to respiratory illnesses such as COVID-19, influenza, and chronic obstructive pulmonary disease (COPD). The company's innovative platform offers a range of services, including remote patient monitoring, therapeutic monitoring, and chronic care management, equipping healthcare providers with the necessary tools to deliver effective care from a distance. Vironix Health's proprietary APIs are designed to be hardware agnostic, allowing integration into various applications utilized by patients, healthcare providers, and employers for enhanced institutional wellness. Founded by a team of dedicated scientists, physicians, technologists, and entrepreneurs, the company was established in response to the global impact of the COVID-19 pandemic, aiming to improve patient outcomes while reducing healthcare costs.

Augmental Tech develops technology that integrates with the human body that enables to access information without the use of hands. The company actively developing discreet hands-free interfaces for people with both situational and severe motor impairment. They want to help others to overcome the physical and sensory limitations of the body and see the mouth as unexplored real-estate for human-computer interaction. Augmental Tech enabling access to computers and increased autonomy for those living with paralysis of the upper extremities. They allowing interaction with a mobile device when constraints imposed by context prevent the use of hands. Augmental Tech was founded in 2019 and is based in Boston, Massachusetts, USA.

FormaPath develops innovative laboratory tools aimed at enhancing tissue sample preparation for diagnostic purposes. The company has created an automated adipose tissue separation instrument designed to improve laboratory automation and patient care by effectively isolating lymph nodes from surrounding fat, resulting in higher yields. Additionally, FormaPath is collaborating with a prominent medical center to develop a specimen preparation system that automates the grossing process in anatomic pathology labs, thereby facilitating the detection of cancer spread. By equipping pathologists with advanced technology, FormaPath aims to provide accurate information that supports timely and reliable diagnoses for patients.

Adventus Robotics develops self-driving power wheelchairs for hospitals and those people with severe physical disabilities. They produce products by using AI and the autonomous technology to avoid motion sickness.

Aidplex is a MedTech startup focused on transforming the orthopedics sector through innovative, patient-centered products. With operations in both the United States and Greece, the company addresses the stagnation in orthopedic product development, which has largely remained unchanged for decades. Aidplex specializes in wearable devices that enable real-time monitoring of patients' health and treatment progress, specifically targeting scoliosis and fracture management. By integrating biometric sensors into their designs, Aidplex provides physicians with critical information necessary to track patient improvements continuously. The company's mission is to enhance the effectiveness and comfort of orthopedic care, ultimately revolutionizing how patients are monitored and treated.

Advanced Interactive Response Systems - AIRS in Newaygo, Michigan, provides oxygen supply monitoring systems for hospitals, homes, and other remote areas. With this system, the patient is able to safely monitor air flow for oxygen tanks. It has an alarm feature that sends updates via text messaging or Bluetooth™. The AIRS devices are also wirelessly linked to each other using a secure and robust mesh networking protocol. Hospitals and medical personnel will greatly benefit from this state-of-the-art monitoring system.

Kobara Medical is focused on addressing the heart failure market, specifically targeting Heart Failure with Preserved Ejection Fraction (HFpEF), a condition impacting over three million individuals and on the rise. The company has developed a minimally invasive therapeutic device that utilizes neuromodulation therapies to improve cardiac function without the need for invasive procedures. By employing the heart's transverse pericardial sinus, the device allows for multi-chamber pacing and combines multiple leads into a single, elegant solution, thus avoiding the complications associated with penetrating blood vessels. Kobara Medical aims to enhance treatment options for patients suffering from heart failure and cardiac arrhythmias by leveraging innovative approaches to heart anatomy.

BestHealth4U focuses on the research and development of advanced solutions for manufacturers of class 1 medical devices. The company specializes in medical adhesive technologies that aim to prevent skin injuries, accelerate healing, and enhance overall patient health. Its innovative and environmentally friendly adhesive products are designed to safeguard patients from skin damage, discomfort, irritation, and infections by improving the attachment of bandages, dressings, and medical devices to the skin. By providing effective solutions, BestHealth4U assists healthcare providers in reducing medical adhesive-related skin injuries and promoting the well-being of patients.

Epios personalized and precision management of brain disorders using daily life monitoring and therapeutics. The Epios system comprises a series of thin leads incorporating sensing electrodes and a miniature implant, inserted beneath the skin. The neural signals are wirelessly transmitted to an external receiver held in place on the skin directly over the implant with a magnet, and from there are conveyed to a wearable data processor and are finally securely stored in the Epios Cloud.

Criam is a biotechnology company based in Braga, Portugal, founded in 2015. It specializes in the research and development of a medical device designed for blood type analysis and the detection of infectious diseases. The company's flagship product offers rapid and accurate testing for various conditions, including HIV, Brucella, tick fever, syphilis, mononucleosis, and meningitis. This portable device operates independently of electricity or laboratory infrastructure, making it accessible for use in diverse environments. Additionally, Criam's technology is scalable, allowing a single reader to perform multiple tests using specific cartridges and advanced computer vision algorithms. By optimizing blood testing services, Criam aims to provide timely health information and improve clinical decision-making.

4Blind is a technology company focused on developing innovative engineering solutions for the blind and deaf-blind communities. The company conducts research and creates products aimed at enhancing communication, education, employment, transportation, and independent living for individuals with visual disabilities. By addressing the unique challenges faced by these communities, 4Blind seeks to expand opportunities and eliminate barriers, enabling deaf-blind individuals to communicate effectively and allowing blind individuals to engage with tactile images. Through its dedicated efforts, 4Blind strives to improve the overall quality of life for people with disabilities.

Serenno Medical is a medical device company based in Yokneam Illit, Israel, founded in 2017. The company specializes in developing a urine output measuring device designed for use in intensive care units (ICUs). Its flagship product, the Sentinel device, provides accurate, automatic, and continuous monitoring of urine output, enabling healthcare providers to detect and assess the risk of acute kidney injury (AKI) in hospitalized patients. This technology enhances patient safety while reducing the workload for medical staff and lowering costs associated with patient care. By offering real-time data on kidney function, Serenno Medical aims to improve fluid management and facilitate early intervention, ultimately helping to prevent severe kidney damage and reduce hospital stays.

Liposphere develops and manufactures AqueousTech, an innovative water-based platform technology that offers advanced lubricants for various medical and technological applications. This IP-protected technology creates a durable protective boundary layer on both biological and synthetic surfaces, effectively resisting high loads and pressures. AqueousTech is significantly more effective than traditional oil- and hyaluronic-based substances, and it is biocompatible. The company's flagship product, AqueousJoint, is designed as a local injectable treatment for knee osteoarthritis. Additionally, Liposphere's technology utilizes hydration water as the key lubricating element, allowing for efficient coating of surfaces and enabling the encapsulation and targeted delivery of active pharmaceutical ingredients or supplements.

SlitLED Israel is a 3D & digital, mobile eye-examination system operating remotely and in real-time.

Pacify Medical Technologies is a medical device startup focused on developing innovative wound care treatments. The company has created a patented device that sprays skin tissue onto wounds, promoting faster healing and recovery. This advanced technology aims to address clinical needs in burn care and other injury treatments, enabling hospitals to enhance their patient care capabilities. By commercializing this next-generation medical device, Pacify Medical seeks to improve the effectiveness of wound healing and provide a novel approach to managing injuries.

IMMA is reinventing the fertility journey by offering women a self-operated remote device to perform their own follow-ups in the comfort, safety, and intimacy of their home, part of a broad system creating a comprehensive, dedicated, and innovative environment.

VenoVision is an AI-driven platform that specializes in contactless cardiopulmonary monitoring, aiming to enhance cardiac care for patients with heart failure and those at risk. By utilizing a thermal imaging monitoring device, VenoVision provides continuous hemodynamic assessments, allowing medical teams to gain insights that were previously only available through invasive cardiac catheterizations. The system is designed to monitor patients post-hospitalization, identifying and alerting healthcare providers to any deterioration in conditions before they escalate, thereby reducing costly admissions to cardiac ICUs. This innovative approach not only improves patient stability at discharge but also facilitates compliance monitoring for various conditions, ultimately contributing to better outcomes for millions of patients.

Kinto.Care is a provider of an online platform to improve communication. The company's platform features user-generated content and digital tools to improve care team collaboration, medication management, and check-in data tracking, enabling the family members of a patient to coordinate care and manage medicines through a single platform.

MindMics is an innovative wearable technology company focused on health monitoring through sound-based platforms integrated into earbuds and hearing aids. By capturing clinically meaningful biometrics in real-time, such as circadian rhythms, breathing rates, body temperature, and heartbeats, MindMics aims to enhance mental performance and overall well-being. The technology allows users to gain insights into their health, facilitating improved focus, satisfaction, and mindfulness. Through this approach, MindMics seeks to provide users with tailored products and experiences that promote mental peace and enhance daily living.

Mosaic health data provides medical records of complete data of a patient's health across the continuum of care

Zibrio is a balance diagnostics company based in Houston, Texas, that was established in 2017. The company specializes in a technology that utilizes insights from postural control and machine learning to detect subtle changes in balance. Originally developed from NASA technology designed for astronauts returning from space, Zibrio's device aims to empower individuals to take charge of their health. By measuring balance and weight, it helps users understand their balance profiles and offers guidance for improvement. The company's mission is to enhance health outcomes, reduce the risk of falls, and promote overall balance and well-being.

4Blind is a technology company focused on developing innovative engineering solutions for the blind and deaf-blind communities. The company conducts research and creates products aimed at enhancing communication, education, employment, transportation, and independent living for individuals with visual disabilities. By addressing the unique challenges faced by these communities, 4Blind seeks to expand opportunities and eliminate barriers, enabling deaf-blind individuals to communicate effectively and allowing blind individuals to engage with tactile images. Through its dedicated efforts, 4Blind strives to improve the overall quality of life for people with disabilities.

myBiometry is developing a platform to monitor/manage patients with chronic disease using biomarker data from proprietary sensors and ML to identify patients at risk of treatment failure. Our initial focus is asthma where treatment failure occurs over 46% of the time (11.5M US patients, $80 billion). We are developing a single use, disposable sensor and device to track a biomarker of inflammation in breath. The data determines changes in adherence, treatment response, and risk of attack.

PREEMIEr Diagnostics is a healthcare provider focused on the health of premature infants, specifically aimed at preventing retinopathy of prematurity. The company has developed a diagnostic device that measures blood glucose levels in these vulnerable patients. This technology assists healthcare professionals in identifying premature infants who require adjustments to their glucose levels, facilitating early detection of potential health issues. By improving the management of glucose levels, PREEMIEr Diagnostics contributes to enhancing the overall health outcomes for premature infants.

Readily3D is a Swiss company based in Lausanne, specializing in volumetric 3D printing solutions. Founded in 2020 as a spin-off from the École Polytechnique Fédérale de Lausanne (EPFL), the company has developed innovative printers capable of producing complex, patient-specific devices in under 30 seconds using tomography. Their technology utilizes a liquid photosensitive polymer, which is cured through dynamic light patterns from multiple angles, allowing for the creation of tailored orthoses for patients with hearing loss and surgical models for medical professionals. This approach not only enhances patient care but also streamlines surgical planning, positioning Readily3D as a leader in the advancement of personalized medical devices.

NemoCare is developing the smartest and most comprehensive patient monitoring and management system. It is an innovative, continuous vital sign data acquisition, analysis and prediction engine that combines unobtrusive wireless wearable sensors and networks, analytical algorithms and big data to provide affordable continuous, high resolution monitoring for all newborns in hospital, and at home. We use design thinking principles to build life-saving technologies that will transform the way healthcare is delivered. Our current area of work is in newborn and maternal care.

Noleus Technologies Inc., based in Houston, Texas, is focused on developing a medical device that enhances patient recovery after abdominal surgery. Their product aims to prevent postoperative ileus and intestinal wall edema, which are common complications that can extend patients' hospital stays and increase healthcare costs. By addressing these issues, Noleus's device facilitates a quicker return of bowel function, leading to fewer complications and enabling patients to be discharged earlier. This approach not only benefits patients by promoting faster recovery but also saves time for physicians and reduces costs for hospitals, addressing an important gap in current medical solutions for abdominal surgery recovery.

Thinks Works is an early-stage biomedical company developing ideas and products that help to solve problems that humans are dealing with. It is the concept of founder Ryan C. Murdock, MD. Through his interactions with his patients dealing with the condition of scoliosis, he saw a need for improvement in the treatment of scoliosis. He set this as a goal and now has begun to build an incredible team to bring his vision to reality so that we may dramatically improve the lives of these patients. Its device is for the non-operative treatment of adolescent scoliosis, a severe curvature of the spine in kids. Approximately 10,000 US kids per year require brace treatment. The current treatment is a custom-made hard plastic brace. It keeps the spine immobile by compressing the ribs. It has poor patient compliance and outcomes at a high patient cost. Its novel device will improve patient comfort, compliance, and outcomes at a lower total patient cost.

Resprana is a wearable company that develops an in-nose wearable air filter. It helps people around the world to own their air and protect themselves in polluted environments.

EM Device is a biotechnology company focused on developing an innovative abscess drainage tool that aims to simplify the treatment of abscesses. This device allows healthcare providers to bypass the traditional incision and drainage approach, which is often lengthy and uncomfortable for patients. By utilizing this new tool, the company significantly reduces the procedure failure rate by 50%, eliminates the necessity for follow-up visits, and enhances overall treatment outcomes. Additionally, the device shortens the time required by healthcare providers, minimizes patient discomfort, and lowers associated costs, thus improving the efficiency and effectiveness of abscess management.

Articulate Labs, Inc. is a medical device company based in Austin, Texas, that specializes in developing wearable technology for the treatment of knee osteoarthritis. Founded in 2009, the company produces KneeStim, a device that employs neuromuscular electrical stimulation (NMES) to enhance muscle function and support rehabilitation during everyday activities. By integrating motion-tracking hardware and clinician input, the device tailors stimulation patterns to align with the user's natural movement, effectively combating muscle atrophy and inhibition associated with chronic conditions or recovery from surgery. Articulate Labs aims to make physical rehabilitation more accessible and effective, allowing patients to engage in their daily routines while receiving therapeutic benefits.

Flare is a smart wearable device that can predict eczema flare-ups. Eczema is a chronic skin condition that affects 20% of children and 3% of adults worldwide. It causes significant anxiety, social impairment, and loss of productivity. Flare helps eczema patients take control of their condition by leveraging state-of-the-art sensor technology and predictive analytics to monitor eczema flares and guide treatment.

Levaté designs a lightweight wheelchair. This lightweight wheelchair accessory restores reach and independence, giving people the flexibility to work, play, and love in their daily lives. The lift attaches and detaches quickly from the wheelchair and raises to eye level or any height in between to improve vision and reach in any environment - high shelves at the grocery store, the refrigerator or cabinets at home, gas stations, public restrooms, car transfers, shopping.

Lainomedical is engaged in the development of respiratory devices, focusing on innovative solutions for the administration of medication through inhalation. The company specializes in designing and manufacturing nebulizers used to treat conditions such as asthma and cystic fibrosis. Their products are engineered to minimize medication errors and eliminate the need for cleaning or disinfection, thereby enhancing treatment outcomes for patients and improving their overall quality of life. Additionally, Lainomedical offers an OTC solution portfolio that incorporates a patented delivery technology aimed at the nose and throat area, further expanding their range of pharmaceutical offerings.

Think and Zoom is a developer of assistive technology aimed at individuals with visual impairments. The company focuses on creating innovative solutions that enhance educational and economic opportunities for those with disabilities. Its flagship product employs advanced glass technology to facilitate hands-free visual magnification, allowing users to zoom in on objects simply by thinking. This unique approach empowers visually impaired individuals to engage more fully with their environment and improve their daily experiences.

Medical Elution Devices features polymer-coated devices containing medication(s) that is engineered to adhere to the surface of existing chest tubes, endotracheal tubes, implants, etc., and elute drug over a pre-determined period.

Solenic Medical, a medical device company that develops a non-invasive treatment for infected metallic implants in the body. The company leverages the properties of alternating magnetic fields (AMF) generated from external coils to eradicate biofilm on the surface of medical implants. This non-invasive treatment addresses a major complication of various surgeries, such as knee and hip replacements, as well as in trauma-related implants such as plates and rods. Its AMF technology has the potential to completely replace the very expensive and risky two-step revision surgical procedure, which is the current standard of care for chronic infections on medical implants. Rajiv Chopra and David Greenberg founded it in College Station, Texas in 2019.

ChondroNest is developing the application of this intellectual property for the reconstruction of Hyaline cartilage. They are aiming to conduct preclinical tests on animal models for two indications, the Osteochondritis and subsequently the Osteoarthrosis. After the first in-man preclinical trials the product will be licensed to major MedTech companies for sales and marketing while they will retain the production of ChondroNest™ pastes.

EarlySight start-up company is founded in order to accelerate the development and to bring the technology to clinics.

Walk With Path develops wearable products aimed at improving mobility and health for patients, particularly those affected by diabetes and movement disorders. The company’s flagship offering is a smart insole equipped with biofeedback technology and sensors, designed to enhance balance and prevent complications such as foot ulcers in diabetic patients. Additionally, Walk With Path has introduced Path Finder, a specialized shoe designed for individuals with Parkinson's disease to alleviate the 'freezing of gait' phenomenon, which can leave users feeling immobilized. Path Finder is recognized as a medical device with supporting evidence published in Neurology. The company's products not only provide therapeutic benefits but also offer data insights and analytics for both end users and healthcare professionals, facilitating gait analysis and promoting better mobility in various populations.

GaitIQ’s™ mission is to create an affordable, accessible, and easy-to-use application for Alzheimer’s screening in primary care. Our machine vision and artificial intelligence-based software measure subtle changes in gait (how a person walks) correlated with future dementia. Early detection and intervention provide hope to prevent or slow the progression of the disease to debilitating symptoms we recognize as dementia. Today fewer than 50% with dementia ever get a diagnosis.

Tremedics develops bioresorbable technology for congenital heart disease patients with congenital heart disease need devices that resorb within their bodies as they grow. Their technology utilises a minimally invasive surgery procedure for stent delivery and permits vessel growth as the stent resorbs in the body.

Grapheal is a Medtech startup focused on developing embedded and wearable biosensors that leverage graphene transistors for enhanced functionality. Their devices are designed to be minimalistic and digital, enabling the dosing of biomarkers and detection of pathogens through a smartphone interface. By integrating advanced sensing nanomaterials with wireless connectivity and data analysis capabilities, Grapheal's biosensors facilitate field diagnostics and remote patient monitoring. This approach aims to make healthcare more accessible and accurate, allowing medical professionals to effectively monitor patient progress and healing.

Exomys is focused on creating passive and modular exoskeletons tailored for industrial environments, aimed at assisting employees during prolonged standing shifts. Their innovative design features a carrying mechanism akin to a mobile chair, which alleviates the strain on the legs by redistributing weight to a mechanical structure. This design allows users to transition comfortably between standing, sitting, and squatting positions without experiencing discomfort or exposure to harmful postures. By integrating all mechanical components discreetly beneath work pants, Exomys enhances user safety and comfort compared to existing exoskeleton systems, which often protrude from clothing. Ultimately, this technology is intended to boost productivity and support long-term health for workers engaged in demanding physical tasks.

Relavo, LLC, founded in 2018 and based in Baltimore, Maryland, is a medical device company focused on improving the treatment of kidney failure patients through innovative technology. The company's flagship product, PeritoneX, is designed to enhance home dialysis by reducing the risk of infection associated with peritoneal dialysis. This in-line connection device works by disinfecting all connection points in the dialysis system before treatment, thereby aiming to minimize the occurrence of peritonitis. Relavo's approach seeks to make home dialysis safer and more accessible for patients, ultimately improving their quality of life.

Rapid Liquid Print is working on 3D printers that create stretchy products for industrial materials. Their services include medical devices, footwear, home goods, furniture, aviation, and automotive components.

Relavo, LLC, founded in 2018 and based in Baltimore, Maryland, is a medical device company focused on improving the treatment of kidney failure patients through innovative technology. The company's flagship product, PeritoneX, is designed to enhance home dialysis by reducing the risk of infection associated with peritoneal dialysis. This in-line connection device works by disinfecting all connection points in the dialysis system before treatment, thereby aiming to minimize the occurrence of peritonitis. Relavo's approach seeks to make home dialysis safer and more accessible for patients, ultimately improving their quality of life.

Articulate Labs, Inc. is a medical device company based in Austin, Texas, that specializes in developing wearable technology for the treatment of knee osteoarthritis. Founded in 2009, the company produces KneeStim, a device that employs neuromuscular electrical stimulation (NMES) to enhance muscle function and support rehabilitation during everyday activities. By integrating motion-tracking hardware and clinician input, the device tailors stimulation patterns to align with the user's natural movement, effectively combating muscle atrophy and inhibition associated with chronic conditions or recovery from surgery. Articulate Labs aims to make physical rehabilitation more accessible and effective, allowing patients to engage in their daily routines while receiving therapeutic benefits.

Juniper Biomedical is a medical device company focused on implantable neuromodulation technology aimed at improving pelvic health. The company has developed a micro-implant that provides precision treatment for various pelvic health conditions by modulating distal target nerves locally. This technology specifically stimulates only the target nerves, allowing for less invasive and safer therapeutic options. It addresses a range of issues, including incontinence, sexual dysfunction, and chronic pain, offering patients more effective solutions for managing their health concerns.

CATHWEAR is a medical underwear firm with a proprietary catheter leg bag and FDA registration. It is a medical device business that offers patients privacy, dignity, and a high standard of living during their treatment and recovery. to restore the dignity and privacy of those who have received medical care in order to improve their quality of life both during treatment and recovery.

myBiometry is developing a platform to monitor/manage patients with chronic disease using biomarker data from proprietary sensors and ML to identify patients at risk of treatment failure. Our initial focus is asthma where treatment failure occurs over 46% of the time (11.5M US patients, $80 billion). We are developing a single use, disposable sensor and device to track a biomarker of inflammation in breath. The data determines changes in adherence, treatment response, and risk of attack.

Mantle Biotech is a company focused on developing medical diagnostic devices that address unmet needs in global health. Founded in 2019 and headquartered in Cambridge, Massachusetts, the company specializes in engineering binding proteins capable of accurately identifying disease biomarkers in patient samples. Utilizing directed evolution to modify heat-stable proteins derived from microbes, Mantle Biotech produces high-quality binding proteins that are more stable and affordable than traditional reagents. These innovative reagents can be adapted for various diseases and testing formats, providing clinics with a reliable and cost-effective alternative to conventional diagnostic methods.

Eyedea Medical is a medical company focused on advancing treatments for corneal diseases by enhancing the accessibility and effectiveness of vision-restoring corneal procedures. The company has developed a single-use graft preparation system that streamlines the processing of corneal tissue, which not only improves yields but also expands the donor pool. This innovation ensures that high-quality grafts are available for cornea transplants, allowing eye care professionals to lower costs and enhance their capacity to perform successful procedures.

Aniluxx Biotechnology, Inc. is a biopharmaceutical company focused on developing innovative topical therapeutics for companion animals, specifically targeting skin diseases such as atopic dermatitis and osteoarthritis. Founded in 2019 and located in Chapel Hill, North Carolina, the company aims to improve the health and well-being of pets by utilizing a pipeline of topically formulated therapeutics based on compounds that have demonstrated safety and efficacy in humans. These therapeutics are designed to be easy to apply and virtually unnoticeable, minimizing the harsh side effects commonly associated with systemic medications. Through its efforts, Aniluxx Biotechnology seeks to provide effective and user-friendly treatment options for dogs, cats, and horses suffering from various skin conditions.

Hubly Surgical Inc. is a medical technology company focused on enhancing patient outcomes and improving the quality of care in neurosurgery. Founded in 2018 and based in San Francisco, California, with an additional office in Chicago, the company has developed an integrated electric drill system that replaces traditional free-hand techniques. This innovative device aims to reduce the rate of lethal complications associated with surgical drilling and is designed to facilitate bedside intracranial access, decreasing the reliance on operating rooms. Hubly's mission is to make its safety technology the standard of care for medical drilling, ensuring that both standard and underserved settings can benefit from improved surgical procedures.

Mente develops a surgical instruments tracking system aimed at enhancing the surgical experience while minimizing costs for hospitals, surgical teams, and patients. The company's innovative approach employs predictive analytics to monitor surgical instruments in the operating room, generating reliable, real-time data streams. This technology significantly improves resource management, ensuring that healthcare teams have the necessary tools readily available during surgeries. By focusing on efficiency and effectiveness, Mente seeks to transform the operational dynamics of surgical procedures.

DynamiCare Health, Inc. is a Boston-based company that offers a digital platform aimed at helping individuals reduce their use of drugs, alcohol, and tobacco. Founded in 2016, the platform integrates a smartphone application with substance testing hardware and a telehealth support system. It employs automated Contingency Management, an evidence-based approach shown to be effective in numerous clinical trials, to motivate users through positive reinforcement. Members can earn monetary rewards for maintaining sobriety, attending treatment, and completing self-guided therapy modules. The platform also features a DynamicCare Analytics portal, allowing healthcare providers to monitor participants' progress and receive real-time alerts regarding their risk levels. By combining technology with personalized support, DynamiCare Health seeks to guide individuals toward achieving healthier lifestyles.

DynamiCare Health, Inc. is a Boston-based company that offers a digital platform aimed at helping individuals reduce their use of drugs, alcohol, and tobacco. Founded in 2016, the platform integrates a smartphone application with substance testing hardware and a telehealth support system. It employs automated Contingency Management, an evidence-based approach shown to be effective in numerous clinical trials, to motivate users through positive reinforcement. Members can earn monetary rewards for maintaining sobriety, attending treatment, and completing self-guided therapy modules. The platform also features a DynamicCare Analytics portal, allowing healthcare providers to monitor participants' progress and receive real-time alerts regarding their risk levels. By combining technology with personalized support, DynamiCare Health seeks to guide individuals toward achieving healthier lifestyles.

Artiria Medical SA develops innovative micro-actuated devices aimed at treating vascular diseases, particularly in the brain. Founded in 2019 and based in Lausanne, Switzerland, the company focuses on enhancing the precision and control of surgical procedures involving catheters and guidewires. Its technology facilitates micromotion within brain arteries, thereby improving navigation during stroke treatments. By enabling surgeons to perform these complex procedures with greater accuracy, Artiria Medical contributes to better patient outcomes and the potential to save lives.

VenoStent, Inc. is a clinical-stage tissue engineering company based in Nashville, Tennessee, with an additional office in Houston, Texas. Founded in 2017, it specializes in the development of bioresorbable smart polymers designed to enhance vascular surgery outcomes. The company’s primary product, SelfWrap, is a perivascular wrap that functions as an external stent, providing mechanical support to veins and promoting outward growth. This innovative technology aims to reduce complications at the vein-artery junction in dialysis patients, particularly by minimizing vein collapse and improving the usability of arteriovenous fistulas (AVF). By utilizing a new class of shape-memory polymers that do not require sutures, VenoStent's approach reduces surgery time and lowers the risk of infection, ultimately enhancing the quality and length of life for patients with chronic kidney disease undergoing hemodialysis.

Pocket Innovations solve the common complication of pocket hematoma associated with pacemaker implants. This new medical device is the first preventative solution.

ZygoFix is a medical device company focused on spine technology. It has developed a three-dimensional printed implant designed to lock the facet joint of the lumbar spine. This innovative device leverages the anatomy of the spine to provide stability, moving away from traditional external screw-based systems. By eliminating the need for pedicle screws, ZygoFix aims to reduce the risks associated with improper screw placement, enhancing patient safety and outcomes in spinal surgeries.

Butterfly Medical Ltd is a medical device company based in Yokne'am, Israel, founded in 2014. The company specializes in developing an innovative implantable device designed to treat Benign Prostatic Hyperplasia (BPH), commonly known as enlarged prostate. This device offers a fast, simple, and minimally invasive alternative to conventional BPH treatments, such as medication and surgery. It can be placed in under ten minutes in an office setting, using local anesthesia and without the need for surgical incisions or tissue removal. This approach aims to provide a long-term solution with minimal side effects, eliminating the need for hospitalization or general anesthesia. Early clinical trials have shown promising results, with effective outcomes in relieving blocked urethras and no reported side effects. Butterfly Medical is advancing further clinical studies at leading medical centers in Europe to validate its device's efficacy and safety.

Miraqules is a healthcare company that provides care medical solutions and introduced StopBleed.

Regenosca SA is a Swiss company based in Lausanne that specializes in the development and commercialization of medical implants designed for bladder reconstruction. Founded in 2019, the company offers sterile, off-the-shelf implants that serve as alternatives to autologous tissue substitutes for soft tissue repair. These innovative biomaterials aim to enhance bladder preservation and minimize scarring, ultimately improving patients' quality of life. By focusing on easy-to-use medical devices, Regenosca is committed to advancing surgical practices and patient outcomes in bladder-related procedures.

Nanochon is focused on creating innovative implantable medical devices designed to address cartilage damage in joints. Utilizing advanced 3D printing techniques and a unique nanomaterial, the company aims to develop solutions that not only replace lost and damaged cartilage but also promote the growth of new tissue. This approach allows medical practitioners to access cost-effective and on-demand devices that enhance treatment outcomes, particularly for young and active patients suffering from knee injuries and diseases. Through its technology, Nanochon seeks to improve the overall quality of care in orthopedics.

MDM Wound Ventures is a medical device manufacturing company that develops and manufactures innovative and disruptive products for wound care and surgical providers to improve patient outcomes and decrease costs. The company was founded in 2014 and headquartered in Scherts, Texas.

ZeoVation Inc., founded in 2016 and located in Columbus, Ohio, specializes in the production of nanozeolites and hierarchical zeolites. These advanced materials are designed to enhance a variety of consumer products, including skin care lotions, sunscreens, and laundry detergents, by improving the efficiency of water softeners and filtration systems. ZeoVation also supplies zeolite materials to various markets such as sun and skin care, home care, healthcare, coatings, and water and gas purification. The company focuses on developing innovative solutions, including a controlled-release antimicrobial and antiviral particle that can be integrated into various applications like sprays, coatings, and textiles. This technology aims to combat the spread of antibiotic-resistant bacteria and viruses, including SARS-CoV-2, thereby contributing to safer and cleaner products.

VisusNano Ltd. is a privately held pre-clinical company developing a drug-eluting intraocular lens implant, for use in patients undergoing cataract surgery. By improving patient outcomes, obviating the need for eye drops after surgery, and avoiding the need for laser treatment after surgery, our project has the potential to revolutionise cataract surgery in both the human and veterinary markets.

S-There is a company that has developed an innovative smart toilet device aimed at improving health monitoring. This passive medical device allows users to track their hydration levels and understand how environmental factors impact their hydration. Through a mobile application, S-There provides users with detailed insights into their hydration quality and trends, enabling them to make informed decisions about their health. By offering personalized feedback, the device aims to assist individuals in managing their hydration effectively and addressing chronic health issues.

NEVA is a vascular access company mobilizing device placement services for hospitals, rehabilitation, long-term care, hospice, and home health organizations. Establishing appropriate vascular access is a common problem faced by healthcare organizations in our rural communities. Partnership with NEVA results in improved patient care quality increased access, reduced financial burden for facilities, and improved resource distribution in a society faced with a nursing/healthcare shortage.

Annaida Technologies has developed a groundbreaking device, EmbryoSpin, that performs microscopic Nuclear Magnetic Resonance (“µNMR”) at a scale 10-fold better than existing technologies.

DEBN is a medical company focused on enhancing prostate biopsy procedures by developing an innovative drug-eluting biopsy needle. This device is designed to reduce the risk of infectious complications associated with prostate biopsies. By delivering a targeted antibiotic combination directly to the prostate, the needle addresses potential infection sites more effectively than traditional methods. Its polymer-coated design allows for the co-administration of various antibiotics, expanding their spectrum of activity. This approach not only improves the efficacy of infection prevention but also enables the use of more effective antibiotics that are typically not suitable for oral prophylaxis.

Dyad Medical Inc. is a company that specializes in developing a cloud-based platform for automated analysis and interpretation of cardiac and cardiovascular images. Founded in 2018 and headquartered in Allston, Massachusetts, its software enhances the assessment of heart anatomy and physiology, facilitating rapid diagnosis and patient triage. The platform supports heart characterization using Magnetic Resonance Imaging (MRI), analyzes intravascular images to evaluate plaque content and stent deployment quality, and automates valve sizing for percutaneous aortic valve replacement. By integrating machine learning and advanced analytics, Dyad Medical's solutions assist healthcare professionals in making informed treatment decisions in clinical settings and contribute to research efforts by optimizing observations and conclusions.

CyberRed develops a unique and innovative solution for addressing the growing global threats of IoT devices from cyber-attacks. Our technology provides a point of entry, early detection, and containment, mitigating the attack's effects, preventing the network and connected devices from being compromised. We develop and implement the “Moving Target Defense” (MTD) Technology in the IoT devices (medical imaging equipment, etc.). WE protect the communication that IoT devices communicate to assure nothing comes in or goes out from attacks. We prevent breached devices from compromising the network. The MTD obfuscates the local network hosts to hackers from inside (LAN: Wi-Fi attacks) and outside (WAN: Vulnerabilities Scans, MiM attacks, etc.). With our Deception Technology (MTD Plus), we can detect, analyze and defend against zero-day and against advanced attacks.

GyroGear is a multidisciplinary team composed of designers, engineers, and medical professionals focused on developing innovative solutions for individuals with hand tremors caused by Parkinson's disease and essential tremor. Their flagship product, the GyroGlove, is a wearable device that utilizes advanced aerospace-grade gyroscopes to mechanically stabilize hand tremors. By addressing this critical issue, GyroGear aims to enhance the quality of life, independence, and dignity of those affected by these conditions. The company is dedicated to providing an effective and straightforward solution for managing hand tremors, thereby improving daily functioning for its users.

Buoy provides a personalized all-in-one platform to help guide consumers back to health. Whether it's chatting about symptoms with Buoy Assistant to get help in the moment of sickness or researching benefits through Buoy Dashboard, Buoy is available 24/7 to help make self-diagnosis and navigating the healthcare system simple and easy. For employers, Buoy can be custom configured to surface benefits information and wellness programs, guide employees to in-network providers, and fully integrate with other health portals. The company was founded in 2014 and is headquartered in Boston, Massachusetts.