MassChallenge

CloEE is an AI digital advisor focused on enhancing sustainability and operational efficiency in discrete manufacturing. By utilizing generative AI, it provides real-time data analysis from manufacturing equipment, as well as manufacturing execution systems and enterprise resource planning systems. CloEE aims to improve Overall Equipment Effectiveness (OEE), significantly reduce energy consumption by 30%, and minimize emergency stops by 95%. The platform offers quick and cost-free project implementation, facilitating manufacturers in saving time and money while addressing critical challenges such as production downtime, delivery delays, and high defect rates. Having connected 25,000 machines across 25 countries, CloEE promotes a new model for efficiency and emission management, ultimately helping manufacturers reduce carbon emissions and drive annual revenue growth.

EcoAct Tanzania is a manufacturer focused on energy conservation and sustainable building materials by recycling post-consumer plastic waste. The company employs chemical-free plastic extrusion technology to transform waste plastics, packaging materials, and agricultural byproducts into durable and eco-friendly plastic lumber. This innovative approach not only provides a viable alternative to traditional wood timbers but also ensures that the resulting products are termite-free, resistant to rot, and cost-effective. By converting waste into valuable materials, EcoAct Tanzania contributes to environmental sustainability while offering affordable solutions for construction and building needs.

Equal Threads offers designing materials, garments, fabric, wearable microfilm, textiles, soft materials, innovative materials, covering, upholstery, new materials, and stone materials for sale.

Seprify is a manufacturer specializing in cellulose-based products aimed at promoting sustainability within various industries. The company develops plant-based cellulose white pigments and opacifier solutions designed to serve as alternatives to traditional titanium dioxide. These pigments are derived from renewable materials that are cost-effective, biocompatible, and easily processed, allowing for scalability using established industrial methods. Seprify's offerings cater to a range of sectors, including paints, inks, cosmetics, pharmaceuticals, and food, enabling businesses to create safer and more sustainable products. By focusing on cellulose-based solutions, Seprify supports the transition toward a circular economy and encourages the adoption of environmentally friendly practices among its clients.

Sunbird Straws manufactures drinking straws from dried fallen coconut leaves, which helps to prevent leaf burning, reduces the use of single-use plastic straws, and provides employment for rural women.

True Concepts Medical Technologies is a medical company that focuses on reducing financial waste in the healthcare system while improving patient outcomes. It delivers innovative and manufacturable solutions based on clinical experience. The company's flagship series of novel, cost-effective, technologies developed with the potential to save billions of dollars annually. True Concepts Medical Technologies' innovative devices deliver safe and effective solutions that reduce errors, provide consistent clinical delivery, and reduce costs. The company is creating these devices with the product development horsepower of Pixel and Timber a product design and development team that has developed dozens of innovative medical devices for clinician-inventors, startups, and manufacturers alike. True Concepts Medical Technologies was founded in 2017 and is headquartered in Centerville, Ohio, USA.

Tree for the The goal is to increase the electric guitar's accessibility while concurrently shifting the source of its materials from an extractive, colonialist origin to a sustainable one.

AC3D is a US-based developer of advanced 3D printing technology aimed at addressing the global housing crisis, waste issues, and climate change. The company specializes in large-scale construction through its proprietary additive manufacturing techniques, allowing for the automation of the construction process. By producing buildings layer-by-layer from computer-generated designs, AC3D enables clients to significantly reduce construction costs while enhancing speed and sustainability. The company offers comprehensive solutions, including 3D printers, materials, software, and house designs, catering to construction companies both in the US and internationally. With a focus on transforming the construction industry, AC3D operates within a vast $14 trillion market, promoting greener and more efficient building practices.

Seprify is a manufacturer specializing in cellulose-based products aimed at promoting sustainability within various industries. The company develops plant-based cellulose white pigments and opacifier solutions designed to serve as alternatives to traditional titanium dioxide. These pigments are derived from renewable materials that are cost-effective, biocompatible, and easily processed, allowing for scalability using established industrial methods. Seprify's offerings cater to a range of sectors, including paints, inks, cosmetics, pharmaceuticals, and food, enabling businesses to create safer and more sustainable products. By focusing on cellulose-based solutions, Seprify supports the transition toward a circular economy and encourages the adoption of environmentally friendly practices among its clients.

Wave Company is a diversified smart apparel firm focused on enhancing athletic performance and recovery through innovative technology. Its flagship product, WaveWear, utilizes patented compression and kinesiology features to aid in injury prevention and recovery for athletes. The company leverages its proprietary conductive silicone technology, Elecsil, to analyze human movement and enhance training experiences. In addition to developing advanced sportswear, Wave Company produces and sells core material technologies, including its bio-silicone technology, to various sectors such as sportswear, healthcare, and smart wear. This approach allows Wave Company to distribute finished products directly to consumers or license its material technologies to other brands, similar to established names in the industry.

We founded AtomicAI to bring advances in computing and machine learning to nanomaterials manufacturing. We believe that nanomaterials will transform energy, electronics, and quantum technologies. But nanomaterials are really hard to make. We're here to help.

Refined Imaging specializes in advanced imaging technologies that facilitate the authentication of additively manufactured parts and the identification of counterfeit items. The company's platform employs interferometry techniques, including microfabrication, X-ray, and neutron grating interferometry, to generate precise images based on the interaction of electromagnetic waves. This imaging process is repeatable, allowing for consistent data comparison with blockchain data files to verify authenticity. By providing a cyber-physical trust anchor, Refined Imaging enhances the reliability and security of manufacturing processes across various industries.

RoadPrintz, Inc. is a manufacturer based in Cleveland Heights, Ohio, specializing in robotic equipment for road painting and pavement markings. Established in 2018, the company develops machines that efficiently survey, map, paint, and repaint road markings for various traffic signs, including turn arrows and lane separators. The primary objective of RoadPrintz is to enhance road safety by making effective visual street markings more affordable and accessible. By utilizing robotic technology, the equipment allows traffic engineers and road painting contractors to apply paint schemes on roads quickly, thereby reducing the risk of accidents and improving overall road safety.

Spiral Technology specializes in developing augmented reality platforms aimed at enhancing the efficiency of factory workers during quality inspections. By leveraging augmented reality and machine learning, the company helps improve accuracy and reduce error rates in inspection processes. Their software is designed to operate on head-worn mixed reality devices, providing essential intelligence to field workers. This technology enables technicians to concentrate on identifying issues that arise at the intersections of various systems, thereby streamlining operations and facilitating better decision-making in industrial environments.

FLITE Material Sciences specializes in surface engineering, focusing on protecting industrial surfaces from rust, ice, and fouling through innovative laser techniques. These patented methods eliminate the need for toxic and temporary chemical coatings commonly used in priming, painting, and cleaning, thereby enhancing product safety and resilience. By applying its technology in both manufacturing and maintenance processes, FLITE contributes to a significant reduction in the use of harmful chemicals, promoting environmentally friendly practices. The company's techniques not only prevent corrosion and ice buildup but also improve the adhesion of lubricants and other treatments, enabling clients to create durable surfaces without the drawbacks associated with traditional chemical coatings.

Ottan is an impact-oriented startup focused on up-cycling food and agricultural waste within a circular economy framework to mitigate plastic use and conserve natural resources. The company specializes in the development and production of sustainable bio-composite materials designed as alternatives to traditional materials like wood, stone, and acrylic solid surfaces. These eco-friendly materials, known as Ottan Materials, are applicable in various industries including cladding, furniture, and housewares. By utilizing biological and food waste as raw materials, Ottan enables designers to engage in zero-waste practices, promoting environmentally responsible interior and industrial design solutions.

Cytronic AG is the brand for compact and user-friendly linear drives and the market leader with the worldwide unique electric cylinder.

Loo Works limited manufactures sustainable components from solid waste materials to create container based toilet in every home

Nautilus Defense specializes in the development and manufacturing of advanced systems for maritime surveillance and structural monitoring. The company creates integrated textile and composite systems that incorporate strain-sensing yarns, antennas, and wearable technologies. These innovations allow for the monitoring of structural assets and their environments, enhancing performance through rapid experimental development. Nautilus Defense's offerings include deployable systems, device arrays, and embeddable systems, all designed to deliver cutting-edge capabilities efficiently.

IndustrialML is a Boston-based startup founded in 2018 that focuses on enhancing the efficiency of industrial operations. The company develops enterprise software aimed at maximizing uptime and minimizing waste in manufacturing environments. Its platform collects, cleans, and curates data from factory sensors and enterprise IT systems, facilitating process monitoring and real-time analytics. By providing actionable insights to operators and engineers, IndustrialML enables factories to improve productivity and streamline operations, ultimately making manufacturing processes smarter and more responsive to operational demands.

Ouli is a skincare manufacturing company s[ecializes in regenerating axolotl salamander and synthetic biology to extract.

Global Security Advancements helps the consumers and defense industry along with firearm manufacturers and retail companies. It develops, manufactures, and markets "TRA-SOR" the "World's First IoT Safe Storage System".

Adapt fit manufactures magnetic sewn strips in the place of buttons and zippers to provide easy way of dressing to patients.

Asystom is a company that specializes in predictive maintenance solutions for industrial equipment. Established in 2016, it focuses on developing systems that integrate sensors and embedded intelligence to proactively prevent equipment breakdowns. Asystom offers a comprehensive, standalone predictive maintenance tool that monitors various components of industrial systems, regardless of their age or design. This approach allows industries to analyze, detect, diagnose, predict, and avoid potential machine failures without facing installation constraints. The company's innovative technology aims to enhance operational efficiency and reduce downtime in industrial settings.

Azucena offera a line of products that mix the corn with typically Mexican ingredients, encompassing the taste of the most demanding palates.

SimpleJohn is a video instruction app for manufacturing companies that helps capture and distribute important operating procedures.

Applied Bioplastics is dedicated to reducing reliance on petroleum-based plastics by offering affordable, high-grade recycled alternatives made from sustainable plant materials sourced from developing nations. The company's bioplastic products aim to diminish petroleum dependency, lower carbon dioxide emissions, and mitigate habitat destruction. By combining plant fibers with recycled or biobased polymers, Applied Bioplastics creates materials that can be easily molded or extruded for use in various industries, including household goods, automotive, appliances, electronics, and outdoor equipment. This approach not only addresses the economic barriers that prevent companies from adopting recycled plastics but also allows them to utilize carbon-negative plant materials as substitutes for traditional petrochemical feedstock without compromising quality or profit margins.

Enzymit is focused on transforming global manufacturing by advancing cell-free bio-production technology, which aims to reduce reliance on scarce resources and enhance sustainability. The company develops novel enzymes using artificial intelligence and deep learning algorithms, enabling the creation of innovative molecular machines that can convert abundant feedstocks into valuable products across various sectors, including pharmaceuticals, cosmetics, food, and materials. By employing small, modular bio-reactors, Enzymit enhances efficiency, reduces costs, and minimizes environmental impact compared to traditional whole-cell bio-production methods. This approach not only fosters resource independence but also allows for greater flexibility in product customization, positioning Enzymit as a competitive alternative to conventional chemical manufacturing.

NALA Membranes specializes in the production of chlorine-stable reverse osmosis membranes designed to enhance water treatment efficiency while minimizing waste and energy consumption. Their patented materials create durable membranes that resist fouling and failure, making them suitable for demanding industrial wastewater applications. By offering solutions that lower operating costs and reduce greenhouse gas emissions, NALA Membranes supports both economic and environmental sustainability. The company's products are utilized across various sectors, including industrial, municipal, residential, and wastewater treatment systems, effectively addressing a range of contaminants and operating conditions.

Kügar is an industrial automation company that offers robotic automation solutions. It specializes in the fields of industrial engineering, manufacturing, and robotics. It was founded in 2013 and headquartered in San Francisco, California.

TechnoCarbon is a France-based startup focused on developing innovative, low-carbon-footprint materials aimed at transforming the architecture and industrial sectors. The company has introduced CarbonFibreStone™ (CFS™), a high-performance composite designed to replace traditional materials such as reinforced concrete, steel, and aluminum, which are known for their environmental impact. By utilizing a patented technology, TechnoCarbon creates a new family of materials that not only meet the technical demands of construction but also promote energy efficiency and resource conservation. CFS™ is suitable for a wide range of applications, including construction, infrastructure, aerospace, defense, luxury goods, furniture, and high-fidelity audio, positioning TechnoCarbon as a key player in the push for sustainable building practices.

Rapid Liquid Print is working on 3D printers that create stretchy products for industrial materials. Their services include medical devices, footwear, home goods, furniture, aviation, and automotive components.

USEFULL is focused on creating a zero-waste future by addressing the challenge of single-use packaging in college and corporate dining environments. The company offers a solution through its stainless steel, returnable takeout containers, which are designed to be checked out and returned easily, similar to borrowing a library book. This innovative approach not only eliminates plastics but also promotes sustainable behavior change among users. Additionally, USEFULL manufactures a range of tech-enabled packaging products, including silicone to-go cups and bowls, which support a plastic-free takeout experience. By partnering with organizations, USEFULL helps them reduce waste, save water, and lower emissions, ultimately aiding in the achievement of their sustainability goals. The containers are durable and intended for use over several years before being recycled, reinforcing the company's commitment to long-lasting, eco-friendly solutions.

Naya’s platform brings the entire physical product design journey into one digital studio, from prompt to product, allowing teams to 10x their outcomes — speed, cost, and customer love.

re:3D reduces production complexity by providing affordable, industrial 3D printers that transform big ideas into tangible realities. With a build volume of eight cubic feet and robust construction, Gigabot can print objects 30x larger than competing desktop models. Up until now, personal 3D printing has been limited to toys and trinkets, while the Gigabot will bring your biggest dreams to life. re:3D's customer base comprises an esteemed group of designers, small business owners, manufacturers, educators, prototypists, and hobbyists in over 30 countries around the globe. Currently, re:3D is scaling manufacturing operations, and exploring alternate materials and feedstocks with global leaders in material and life sciences.

Enzymit is focused on transforming global manufacturing by advancing cell-free bio-production technology, which aims to reduce reliance on scarce resources and enhance sustainability. The company develops novel enzymes using artificial intelligence and deep learning algorithms, enabling the creation of innovative molecular machines that can convert abundant feedstocks into valuable products across various sectors, including pharmaceuticals, cosmetics, food, and materials. By employing small, modular bio-reactors, Enzymit enhances efficiency, reduces costs, and minimizes environmental impact compared to traditional whole-cell bio-production methods. This approach not only fosters resource independence but also allows for greater flexibility in product customization, positioning Enzymit as a competitive alternative to conventional chemical manufacturing.

Polybion is a manufacturer specializing in circular carbon-sourced bio-assembled materials aimed at assisting designers and materials engineers in creating eco-friendly products. By utilizing waste as a raw material, Polybion develops and finishes products that significantly reduce the environmental impact associated with traditional textile materials derived from petroleum or animals. This approach not only promotes sustainability but also contributes to the advancement of the circular economy, enabling customers to adopt more environmentally responsible practices in their design and manufacturing processes.

Māk Studio is an interior design company focused on simplifying the design and production process for commercial interiors. It offers fabrication and design services, creating custom and customizable furniture along with impressive interior elements such as branding walls. By launching its online platform, Māk Tech, the company aims to make these sophisticated design solutions accessible to a broader audience, moving away from the traditionally complicated processes that limited access to a small market. Māk Studio is dedicated to helping clients realize their unique vision and brand through tailored interior solutions.

Hangio is a manufacturer and supplier specializing in hangers for fashion clothing. The company focuses on optimizing the everyday closet experience by providing flexible and durable hangers designed to prevent stretching, wrinkling, bumps, and creasing of garments. With a commitment to accommodating various collar types, Hangio aims to enhance clothing care while making a positive impact on the fashion industry.

MDM Wound Ventures is a medical device manufacturing company that develops and manufactures innovative and disruptive products for wound care and surgical providers to improve patient outcomes and decrease costs. The company was founded in 2014 and headquartered in Scherts, Texas.

Invent Boston design, manufactures and supplies every day routines.

Multiscale Systems produces industrial innovations through technical engineering services and a robust in-house R&D program. The company specializes in metamaterial composites and focuses on advanced manufacturing.

Rhythmo is a company focused on educating teenagers in music and STEM through innovative products. It manufactures music production instruments, including a MIDI drum machine and speaker combo, designed to be accessible and affordable. These products come in a cardboard box and are bundled with an application, sound packs, and tutorials, allowing users to explore music production creatively. Rhythmo's approach emphasizes DIY learning, offering a unique cardboard MIDI controller kit that encourages hands-on engagement and customization. By combining music education with practical tools, Rhythmo aims to inspire the next generation of musicians and creators.

Magnomer is a Boston-based manufacturer that specializes in innovative magnetic inks designed to enhance the recyclability of plastic packaging within a circular economy framework. Founded in 2017, the company offers a unique product called Design2Recycle™, which serves as a design tool for consumer brands and manufacturers, allowing them to improve packaging recyclability without altering existing manufacturing processes. The company's printable magnetizable inks and coatings are specifically developed for use in multi-layer packaging, addressing the challenges associated with recycling these materials. By employing magnetic sorting technology, Magnomer enables recycling facilities to more efficiently separate and process multi-layer plastics, which are typically difficult to recycle using conventional methods.

Folia Water is a manufacturing company dedicated to producing affordable water filters designed to enhance access to clean drinking water, particularly for underserved populations. The company's flagship product, Folia Filters™, utilizes antimicrobial filter paper embedded with silver nanoparticles to effectively reduce waterborne pathogens. With a focus on cost efficiency, Folia Water employs a patented coating process that transforms standard industrial paper into a highly functional material, enabling the production of filters at a fraction of the cost of traditional methods. By leveraging large-scale paper machinery, Folia Water aims to improve the quality of life for working-class consumers by providing them with a low-cost solution for purified drinking water.

Takachar is focused on creating a network of waste management enterprises in Kenya that convert agricultural residues into eco-friendly charcoal, providing an affordable cooking fuel for low-income households. The company has developed low-cost technologies that can be locally manufactured and have been successfully tested in Kenya over the past three years. Since its inception, Takachar has assisted in establishing seven local waste-to-charcoal enterprises, some of which have achieved operational profitability. To date, Takachar has created approximately 100 jobs and sold 50 tons of eco-char. The company aims to demonstrate the long-term financial sustainability of these enterprises, with the intention of developing a franchise network in the future. Additionally, Takachar employs oxygen-lean torrefaction reactors to transform biomass into commercially viable products, helping farmers prevent the open burning of agricultural waste while providing them with opportunities to generate extra income through value-added chemicals.

ApreX Biotech specializes in the development of innovative organ-on-chip systems aimed at transforming pharmaceutical development and personalized medicine. By employing advanced origami folding techniques, the company converts simple, two-dimensional patterns into sophisticated three-dimensional tissue architectures. This technology facilitates the creation of products across various sectors, including pharmaceuticals, chemicals, food, and cosmetics. ApreX Biotech's systems are designed to enhance the efficiency and effectiveness of product development, ultimately supporting the advancement of personalized medical solutions.

THE 1854 CYCLING focuses on addressing generational poverty by creating living wage job opportunities for formerly incarcerated individuals. The company manufactures bicycles, including electric and cargo models, and offers cycling apparel and accessories, promoting an eco-friendly mode of transportation. By providing high-quality cycling products, THE 1854 CYCLING aims to support the health and fitness of its customers while serving as a symbol of a broader movement to empower those re-entering society.

Social Fabric is a sustainable textile center that promotes the use of environmentally friendly and socially responsible textiles. The organization aims to combine a circular economy with innovative technology and decentralized manufacturing to provide customers with customized garments. It operates as a community-based association, focusing on two main areas: integrating refugees into the workforce in Switzerland and enhancing sustainability in textile production. By prioritizing ethical labor practices and minimizing ecological impact, Social Fabric offers individuals access to meaningful and sustainable textile products.

Alkemy Environmental is a cleantech company that offers recycling services to its clients. The company recycles industrial waste streams into concrete aggregate. Its product portfolio consists of expandable lightweight aggregate, ultra lightweight aggregate, and high strength lightweight aggregate. Furthermore, it offers waste management services to its clients. Alkemy Environmental was founded in 2008 by Sofia Bethani and Peter Kombouras and is based in Massachusetts.

Novamet develops a smart data-driven tool to optimize aluminium melting (recycling) processes. Novamet develops Smart Controling System to enhance the efficiency of metling process in Aluminium industries. The approach is based on on-line data acquisition, efficient numerical modeling and machine learning of heat exchanges within a industerial furnace.

KOMP-ACT has developed Modula, an innovative electric actuator solution that is poised to electrify the next generation of the industrial machines in the automation industry for the benefits of the machines builders, end-users and last but not least our environment towards an important reduction of CO2 emissions.

Our ambition at MachIQ Software is to become the leading asset performance management platform for the manufacturing industry where plant operators collaborate with machine builders (OEMs) and digital after-sales services (MRO) companies to achieve maximum asset performance at optimal costs. With over 150,000 machines from 300+ brands, we have already become the largest multi-brand platform in the process manufacturing industry as of 2019. We integrate and interface with internal ERP systems. The platform is hosting two securely separated software for each party: MachIQ SEVA for machine builders. OEMs are able to digital all their after-sales services with one software becoming the "source of truth" for: - Installed-based management - Spare parts sale - Field services - And more! MachIQ APM for producers of the food and beverage industry. Producers are able to digitalise their maintenance activities including: - Asset management - Workforce planning - Spare parts and documentation management - And more!

Insolight is an energy company founded in 2015 that specializes in the development and manufacturing of high-efficiency solar panels. The company has achieved significant advancements in solar technology, with modules reaching a record efficiency of 29 percent, which allows for a reduction in residential solar electricity costs to below 0.1 $/kWh. Insolight's innovative optical technology enhances efficiency while maintaining the simplicity of installation comparable to standard flat panels. The company's solar systems also incorporate an integrated tracking method to optimize energy capture, maximizing solar utility for agricultural applications. Insolight's business model focuses on developing intellectual property, overseeing wholesale distribution, and outsourcing manufacturing, ensuring a streamlined approach to delivering cost-effective solar solutions. The technology has been validated by reputable institutions, demonstrating its potential for widespread impact in both residential and agricultural sectors.

PrintCB Ltd., located in Ness Ziona, Israel, specializes in the manufacture of copper inks designed for printed electronics. These inks aim to replace silver, the most expensive component currently used in the industry, thereby significantly reducing manufacturing costs in a market valued at $70 billion. PrintCB's innovative copper inks are compatible with standard printing processes and do not require changes to existing capital equipment. They can be cured in ambient air using conventional conveyor or box ovens, making them versatile for various applications, including circuitry, sensors, and energy devices. This flexibility allows printing industries to utilize non-brand-specific inks compatible with different dispensing systems, promoting efficiency and cost-effectiveness in production.

Distran, a spin-off from the Autonomous System Lab at ETH Zurich, specializes in the development of advanced acoustic sensors aimed at enhancing safety for industrial workers and minimizing environmental impact. The company focuses on manufacturing ultrasound cameras that cater to various sectors, including oil and gas, power generation, and chemical engineering. Distran's innovative phased-array sensors address the limitations of traditional acoustic sensors, which often struggle to function effectively in noisy industrial environments. By spatially filtering sounds, these sensors enable the detection of defects such as leaks or discharges from a safe distance, thereby allowing clients to protect their workforce and reduce their ecological footprint.

Modvion is a Swedish/ American Engineering and Industrial Design company developing modular designs in renewable engineered wood product materials to simplify and improve construction logistics. Their current area of focus is in wind tower technology. Modvion´s patented module technology enables significantly decreased cost, efficient transportation and streamlined installation of towers exceeding 120 m. Ultimately, this results in increased cost efficiency in the harvesting of wind resources.

Tranquilo, Inc., founded in 2015 and based in Tampa, Florida, specializes in the design and manufacture of portable vibrating mats aimed at soothing infants and aiding in their sleep. The Tranquilo Soothing Mat is lightweight and easily transportable, allowing parents to calm their crying babies by mimicking the comforting sounds and motions of a mother's womb. As of late 2018, Tranquilo operates as a subsidiary of Baby Boom Consumer Products, Inc.

Induo is a textile company that specializes in the production of innovative fabrics designed for apparel brands. The company's flagship product, INDUO® fabric, is engineered to be resistant to stains and perspiration while maintaining the soft touch and comfort characteristic of high-quality cotton. Induo utilizes advanced technology to create breathable and repellent fabrics, focusing on sustainability by recycling complex material blends and poorly sorted apparel waste. This approach allows the company to offer comfortable clothing options at an affordable price, catering to the needs of both consumers and apparel manufacturers.

Induo is a textile company that specializes in the production of innovative fabrics designed for apparel brands. The company's flagship product, INDUO® fabric, is engineered to be resistant to stains and perspiration while maintaining the soft touch and comfort characteristic of high-quality cotton. Induo utilizes advanced technology to create breathable and repellent fabrics, focusing on sustainability by recycling complex material blends and poorly sorted apparel waste. This approach allows the company to offer comfortable clothing options at an affordable price, catering to the needs of both consumers and apparel manufacturers.

Danger!Awesome LLC, founded in 2014 and based in Cambridge, Massachusetts, specializes in laser-cutting and engraving services for a variety of materials, including wood, plastic, paper, fabric, and leather. The company caters to a diverse clientele, including architects, artists, engineers, students, and small businesses, providing customized products tailored to individual needs. In addition to traditional services, Danger!Awesome is pioneering the development of a high-performance, professional solid-state laser cutter designed for consumer affordability. This innovative device cuts metal and works on multiple materials with greater efficiency than conventional CO2 laser systems, addressing the growing demand from design firms, universities, and community spaces for modern, cost-effective laser solutions. Furthermore, the company offers a makerspace where customers can collaborate with designers and technicians to create personalized items, reinforcing its commitment to accessibility and customization in the creative process.

MagnebotiX, established in 2014 and based in Zurich, specializes in the development and manufacturing of magnetic manipulation systems. The company focuses on creating magnetic field generators and micromagnetic agents that facilitate both fundamental and applied research in science and engineering. Their innovative products utilize magnetic fields to enable wireless micromanipulation, making it possible to perform tasks in challenging environments. This includes the use of their systems as untethered mechanical probes for accessing hard-to-reach locations and for delivering targeted cargo in minimally invasive biological studies. MagnebotiX aims to advance research on magnetic phenomena and develop applications for magnetic microrobots, thereby enhancing capabilities in various research fields.

Response Technologies, LLC, founded in 2015 and located in Coventry, Rhode Island, specializes in additive manufacturing and advanced material science. The company develops innovative techniques for creating 3D textile structures and reinforced composites, focusing on sectors such as national defense, energy, aerospace, automotive, and transportation. Notably, Response Technologies manufactures explosion-resistant fuel tanks that enhance safety and effectiveness in fuel containment for its clients across these industries. As of December 2020, Response Technologies operates as a subsidiary of Bell Textron Inc.

Blackburn Energy, Inc. specializes in renewable energy solutions for the commercial trucking industry through its innovative product, RelGen. This technology harnesses kinetic energy from a truck's drive shaft, converting it into electricity via a custom alternator. The generated power is stored in a battery array, enabling it to supply energy to various truck subsystems including liftgates, electric auxiliary power units (APUs), and sensors for driver-assist and autonomous features. Blackburn Energy's solutions aim to reduce reliance on engine idling, thus cutting fuel and maintenance costs while minimizing carbon emissions. The company's products are particularly beneficial for long-haul drivers, providing essential power for climate control and operational needs during rest periods. Blackburn Energy was founded in 2008 and is headquartered in Amesbury, Massachusetts.

WorkSafe Technologies is a company focused on eliminating the causes of frequent workplace injuries through innovative solutions. Established in Northern California, it specializes in ergonomic solutions, employee safety, and services tailored for manufacturing and data centers. By leveraging expertise in product design and development, WorkSafe Technologies aims to address common workplace accidents and enhance overall safety. The company is recognized for its commitment to innovation and professional service solutions, establishing itself as a leader in the field of workplace safety.

Eulysis UK Limited is an innovative device development company focused on improving the storage and delivery of pharmaceutical products. The company pioneer product innovation, Single Vial System, involves a unique manufacturing process which allows the integration of a lyophilized active ingredient(s) and its diluent for reconstitution to exist within the same container. Until now, pharmaceutical products such as vaccines,antibiotics, antidotes that comprised a lyophilized phase and a diluent for reconstitution were manufactured, stored and delivered in two containers. This leads to a number of inefficiencies and potential risks including contamination risks, excessive raw material usage in production, and inefficient usage of transportation and storage means as two vials had to be transported and stored for each final product as opposed to one.

DropWise Technologies Corp. specializes in manufacturing advanced coating materials aimed at reducing carbon emissions in power plants and enhancing the efficiency of thermal systems. The company utilizes a unique vapor-based deposition process, developed in collaboration with leading MIT labs, to create ultra-thin, durable coatings that effectively address fouling and corrosion in heat exchange equipment. These coatings are significantly thinner than conventional options, allowing for improved heat transfer and reducing the need for excessive coolant water. DropWise's technology is applicable across various sectors, including power generation, desalination, HVAC/R, and chemical refining. By chemically grafting coatings to surfaces with precision, DropWise enhances the performance of critical components such as heat exchangers, ultimately enabling operators to maintain higher efficiency and durability while minimizing operational costs. Established in 2014 and based in Cambridge, Massachusetts, DropWise Technologies is poised to transform traditional coating solutions and access markets previously deemed unattainable.

Veraquel Technologies is commercializing a transformative platform technology for the synthesis and manufacturing of peptides, applicable from discovery to large-scale production. This patented technology has the potential to eliminate the need for labor-intensive column separations, revolutionizing the process of manufacturing scale-up and enabling the high-throughput parallel purification of peptides for library-based approaches to drug discovery.

DrinkSavvy is a Boston-based company that manufactures and distributes drinkware such as plastic cups, straws, and stirrers. Its products feature a proprietary, patented technology, integrating indicators into barware in order to provide consumers with a colorimetric indication of the presence of illicit drugs such as GHB, Ketamine, and Rohypnol in their drink. DrinkSavvy was founded in 2009 and is based in Boston, M.A.

CONTINUUS Pharmaceuticals works with pharmaceutical and generic companies under a Build-Own-Operate model. They design, build, and run the manufacturing process directly at the client site. This novel business model provides its clients with an exceptional, ”one-shop solution” for their entire development and manufacturing cycle. CONTINUUS Pharmaceuticals is leveraging a novel continuous manufacturing platform called Integrated Continuous Manufacturing (ICM), initially developed through an $85 M joint research project between Novartis and MIT. In addition, the company is currently collaborating with hospital systems and pharmacy chains to establish its own generic business, where high-quality, low-cost drugs will be manufactured in the United States.

AMS-Qi, established in 2012, supports the global growth of AMS LTD, a company with expertise in optics, fine mechanics, heat transfer, and electronics since 1990. Founded by experts in electro-optics and process control, AMS-Qi focuses on developing and commercializing innovative solutions for the power generation and microelectronics markets in the United States. The company specializes in electricity generation technology designed to enhance efficiency, improve the burning of coal and biofuels, reduce boiler downtime, and minimize pollutant emissions. With its unique turn-key and serial production capabilities, AMS-Qi is committed to addressing customer needs effectively.

99C manufactures build-to-order apparel for the growing me-commerce market and serves as an economic mobility bridge for the local workforce in Lawrence and Lowell. It provides quick-turn performance activewear production, advanced concept incubation, and wearable technology integration for global and emerging brands.

WindGap Medical is a biotech company that manufactures medical devices used to treat patients with severe allergies. The company develops auto-injectors that are filled with heat-stable epinephrine that enable physicians to inject it into a patient suffering from anaphylaxis due to an acute allergy attack. The company was established in 2011 and is headquartered in Somerville, Massachusetts.

TireTech de-vulcanizes tires, creating clean raw materials in demand by manufacturers.

GG's Original is a manufacturer of Gluten-Free gourmet potato pancakes and bakery items for retail and food service organizations.

Bow & Drape Inc. is an online retailer specializing in custom-designed apparel and accessories for women, including bridal clothing and pet products. Founded in 2012 and based in New York, the company allows customers to create unique garments by choosing from a selection of silhouettes, colors, and trims. Once a design is finalized, Bow & Drape manufactures the item in the USA and ships it directly to the customer within two weeks. Formerly known as Zoora LLC, Bow & Drape Inc. has been operating as a subsidiary of Brand Value Growth LLC since November 2019.

Pegasus was established after its founder, an avid bike racer, had a severe accident that nearly cost him his life. Using a patent-pending system of strategically placed sliding fabric layers, the cycling garments are engineered to be light, breathable, and protective. Pegasus Performance produces patent-pending garments that reduce injuries from bike and other sports crashes, improving your safety.

Ministry of Supply, Inc. is a company based in Boston, Massachusetts, that specializes in the design and manufacture of performance professional apparel for both men and women. Established in 2010, the company focuses on creating innovative clothing that addresses the limitations of traditional work attire through advanced materials and purposeful design. Ministry of Supply aims to enhance comfort and functionality in business wear, allowing individuals to perform at their best throughout the workday. By leveraging scientific research and human-centered design, the company produces garments that are tailored to the body's form while maintaining a commitment to sustainability. The products are primarily sold online, reflecting the company's contemporary approach to retail.

LiquiGlide is a viable technology that allows viscous liquids to slide effortlessly. LiquiGlide is the first company to create permanently wet slippery surfaces. There is no other durable solution that makes viscous liquids slide easily.

NBD develops coatings and additives to modify surface wetting properties. NBD focuses on coatings and additives that modify surface wettability. NBD's broad product portfolio can influence surface properties for glass and plastic materials to create ultra-durable and functional surface wetting properties. It was founded in 2012 and headquartered in Brighton, Massachusetts.

Solid Access Technologies, based in Newburyport, Massachusetts, specializes in the manufacturing of ultra-fast solid-state disks designed to enhance business-critical applications. Established in 2002, the company focuses on USSD (Ultra Solid State Disk) products that leverage industry standards and widely available components. Solid Access's solutions have consistently outperformed other storage technologies in benchmarks, supporting their claim of offering the fastest storage solutions globally through standard interfaces like Fibre Channel and Serial-Attached SCSI (SAS). The company operates from its headquarters in the Boston area and conducts research and development, as well as sales efforts, in Prague, Czech Republic. By pursuing global opportunities through direct sales and partnerships across North America, Europe, and Asia, Solid Access aims to provide clients with improved IOPS and bandwidth performance, ultimately reducing operating costs and the risk of SSD failure.

PolyChroma is a LED lighting manufacturer.

ZanaAfrica Group is a Kenyan social enterprise focused on providing affordable, high-quality menstrual products specifically designed for women in Kenya. The organization manufactures Nia sanitary pads, which support over 100,000 females in managing menstruation with dignity. ZanaAfrica emphasizes health education by incorporating informative materials on its product packaging and offering a hotline and chatbot service to address women's questions about menstruation, relationships, and safety. This approach not only meets the immediate needs of women and girls but also fosters a deeper understanding of their bodies. By combining non-profit motivation with business strategies, ZanaAfrica aims to create a sustainable model that can be replicated internationally. Profits generated by the company are allocated to an endowment for the ZanaAfrica Foundation, ensuring ongoing support for its social mission.

Cerahelix, Inc. is a company based in Orono, Maine, that specializes in the design and manufacture of ceramic membrane filters for a variety of applications, including water purification, resource recycling, and biomass processing. Founded in 2011, Cerahelix develops bio-derived products utilizing patented DNA template technology to create sub-nanometer pores in ceramic membranes. This innovative approach allows for the effective filtration of minute particles, enabling the separation of salts, metal ions, and other impurities at the molecular level. The company offers a range of products, including single-channel elements for laboratory and small pilot studies, multi-channel elements for commercial applications, and filter element housings. Additionally, Cerahelix provides laboratory test systems for research and development purposes. Its products serve multiple industries, including food and beverage, mining, pharmaceuticals, and waste-to-energy.