MassChallenge

Via a combination of materials, biotechnology and optics IP, we are developing a microbiological testing solution applicable to pathogens, allergens and spoilage organisms. The core technology enables quantitative and array-based tests for high throughput, low component and overall solution cost, best in class time-to-result, and a hardware design road-map including small footprint and handheld form factors. The combination of consumables incorporating our proprietary materials and biological agents, low-cost hardware and analytics we're developing is uniquely positioned to serve the market.

Walk With Path develops wearable products aimed at improving mobility and health for patients, particularly those affected by diabetes and movement disorders. The company’s flagship offering is a smart insole equipped with biofeedback technology and sensors, designed to enhance balance and prevent complications such as foot ulcers in diabetic patients. Additionally, Walk With Path has introduced Path Finder, a specialized shoe designed for individuals with Parkinson's disease to alleviate the 'freezing of gait' phenomenon, which can leave users feeling immobilized. Path Finder is recognized as a medical device with supporting evidence published in Neurology. The company's products not only provide therapeutic benefits but also offer data insights and analytics for both end users and healthcare professionals, facilitating gait analysis and promoting better mobility in various populations.

MZP Tech is a company focused on point-of-care coagulation analysis, aiming to improve healthcare delivery through innovative diagnostic methodologies. They develop medical devices capable of rapidly analyzing blood samples, utilizing a disposable micro-machined chip and a portable embedded sensing system. This technology allows for the analysis of a single drop of blood within minutes, measuring blood viscosity. By doing so, MZP Tech enables healthcare professionals to conduct early-stage screenings for various conditions, including cardiovascular diseases, blood-clotting disorders, and hyperviscosity-related issues. Their advancements in hemostasis contribute to better management of bleeding and thrombotic risks, enhancing patient care.

SafeGuard Surgical provides much-needed products that will ensure safer surgery for better patient outcomes while lowering costs, preventing additional surgical interventions, and reducing patient length of stay, but most importantly, preventing mortality and morbidity, which is an all-too-common risk of surgery.

Birth By Us empowers mothers and birth attendants to customize their own birthing experience while providing caregivers with the insights and data needed to best assist their birth.

True Concepts Medical Technologies is a medical company that focuses on reducing financial waste in the healthcare system while improving patient outcomes. It delivers innovative and manufacturable solutions based on clinical experience. The company's flagship series of novel, cost-effective, technologies developed with the potential to save billions of dollars annually. True Concepts Medical Technologies' innovative devices deliver safe and effective solutions that reduce errors, provide consistent clinical delivery, and reduce costs. The company is creating these devices with the product development horsepower of Pixel and Timber a product design and development team that has developed dozens of innovative medical devices for clinician-inventors, startups, and manufacturers alike. True Concepts Medical Technologies was founded in 2017 and is headquartered in Centerville, Ohio, USA.

DocNexus is transforming the healthcare landscape by leveraging AI-powered knowledge graphs to enhance access to critical information. The company's platform provides a comprehensive database for key opinion leader (KOL) searches, advanced publication searches, and news aggregation, allowing medical affairs organizations to efficiently find evidence and stay updated on KOLs' digital presence. By delivering insights from millions of scientific publications, clinical trials, and news articles in seconds, DocNexus streamlines the process of connecting healthcare professionals across the ecosystem. This innovative approach enables clients to strengthen their medical affairs strategies and improve scientific exchange.

HME Square is a digital healthcare company focused on developing medical diagnostics and devices that utilize innovative technology for health monitoring. The firm specializes in creating non-invasive glucose monitoring systems designed to measure health data accurately and continuously without the need for blood sampling or needles. By integrating photoacoustics, MEMS device technology, and deep learning into a cohesive digital data platform, HME Square aims to prevent chronic diseases and empower individuals to manage their glucose levels effectively, thereby promoting healthier lifestyles.

Women aged 20-45 cannot get screened for breast cancer because existing solutions are unreliable. However, 81% want to. At The Blue Box, we have built a pain-free, low-cost, sensitive, radiation-free device to detect breast cancer in urine with a sensitivity of 83%. In 2024, we’ll launch into the market, bringing The Blue Box to private gynecology clinics with a Diagnostics-as-a-Service subscription model, and a pay-per-test revenue stream that we’ll share with doctors.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Elythea is an ML/DL-driven platform that obstetricians in any setting use to predict risk for complications of pregnancy (postpartum hemorrhage, c-section, eclampsia) before they ever happen. We use information that is available at the point of care, so we can make the prediction as early as the 1st trimester, allowing doctors months to prepare in advance! We use clinical history/demographic information that is available at the point-of-care, so we can make the prediction as early as the 1st trimester, in developed or developing countries, allowing doctors months to prepare in advance! Knowing high-risk earlier allows for blood/medicine/tailored clinical guidance to be prepared, reducing mortality/costs >90%. Our models use proprietary models to surpass gold standard risk assessments in the current clinical space. Our preliminary clinical trials have demonstrated 3x greater sensitivity for high risk classification of hemorrhage when comapred to the current widely used hemorrhage assessment score.

Aevice Health specializes in non-invasive wearable technology aimed at monitoring respiratory health in real-time. The company develops devices specifically for asthmatic patients, which track and record vital historical data related to respiratory symptoms and medication usage. This technology facilitates the early detection of cardiopulmonary issues, enabling clinicians to monitor patient responses to treatment effectively. By providing critical health insights from the comfort of home, Aevice Health enhances patient care and allows for quicker, more targeted medical interventions.

Ember Sleep is a company focused on improving sleep quality through its innovative sleep apnea treatment platform. The platform features medical devices designed to be more comfortable, effective, and non-invasive for the treatment of sleep apnea. By providing a novel approach to open the airway, Ember Sleep aims to enhance the well-being of patients, enabling them to feel more rested while assisting healthcare professionals in delivering better health outcomes.

Benten Technologies is a social impact company dedicated to democratizing healthcare. The organization has secured approximately $9 million in non-dilutive funding to develop a pipeline of digital therapeutics aimed at making healthcare services more accessible. In addition to its healthcare initiatives, Benten Technologies also provides technology consulting services, which encompass application development, management consulting, quality assurance, and research and development. By leveraging proven system integration methodologies and expertise, the company enables organizations to deliver effective, value-driven business solutions.

Astron Medtech is a medical technology company focused on improving patient outcomes in tendon repair. The company develops disposable minimally invasive surgical devices that significantly reduce recovery time from six months to four months. By utilizing less invasive and sustainable surgical techniques, Astron Medtech aims to enhance the efficiency of surgical services while providing better options for patients undergoing tendon repair procedures.

Card Medic is an app that improves communication between healthcare staff and patients across any barrier, including foreign language; visual, hearing, or cognitive impairment; illiteracy; or PPE. It hosts an A-Z library of digital flashcards replicating clinical conversations around common healthcare topics; multilingual, sign language, easy read, and read-aloud. Improves quality of care, and reduces health inequalities.

Welfie is a health platform designed to support K-12 schools in addressing contemporary health issues among children. It offers a comprehensive data platform that provides health data assessments and insights, enabling parents, healthcare providers, and community health leaders to make informed health decisions for children. Welfie emphasizes a whole-child approach by tracking various aspects of health, including social, emotional, and mental well-being, while also focusing on critical areas such as heart health, nutrition, fitness, and diabetes management. By equipping caregivers and educators with valuable resources, Welfie aims to enhance the overall health and wellness of students.

CBOH is a digital health platform that decentralizes control of health identity and data. It empowers users to control their digital health identity and share verifiable health statuses with whom they choose. It is on a mission to destigmatize health testing and eliminate the spread of transmissible infections.

Eupnoos is a health-tech company specializing in digital healthcare solutions for lung health and disease detection. The company has developed a smartphone-based application that utilizes the device's microphone and camera to perform clinical-grade lung function tests and symptom-guided assessments. This platform enables users to screen, measure, and track the progression of lung health issues. By providing device-agnostic, API-accessible automated testing and data interpretation, Eupnoos supports both clinical and consumer-grade respiratory monitoring devices. The company's services facilitate telehealth and remote patient monitoring, empowering individuals to gain insights into their lung health and access professional healthcare guidance.

Patientory, Inc. is a healthcare technology company based in Atlanta, Georgia, established in 2015. It offers a health data management platform that enables individuals to securely store, manage, and share their health information. The platform empowers patients to take control of their medical records and chronic illness management while facilitating better communication and support between healthcare providers and patients. By integrating a blockchain-enabled network, Patientory streamlines access to health data, enhances care coordination, and provides insights into health outcomes. This approach aims to democratize health data ownership, reduce healthcare costs, and improve overall patient engagement and health management.

Ferrum Health, Inc. is a health technology company based in Santa Clara, California, that develops an artificial intelligence platform aimed at preventing medical errors and improving patient outcomes. The platform analyzes patient data across health systems to identify gaps in care and deploys multiple computer vision algorithms to evaluate radiologic images for commonly overlooked pathologies, such as lung nodules and fractures. Additionally, a proprietary natural language processing algorithm correlates these findings with physician notes, enabling hospital quality officers to address potentially missed diagnoses. Founded in 2017, Ferrum Health focuses on ensuring quality assurance in critical healthcare decisions, thereby enhancing the overall patient care experience through the integration of AI-driven tools.

Together by Renee is a free app that uses generative AI to streamline and automate health tasks like ordering refills, booking appointments and completing forms in an easy user experience perfect for the 123 million aging Americans managing diabetes, obesity, hypertension, and more. Together measures vital signs like blood pressure via smartphone camera - with no devices or wearables required. Together requires no data entry, typing or integration to legacy systems, using just AI to automate patient-centric care coordination. 67% of Together’s first 15,000 users are over 55 years of age and Together enjoys NetPromoter score of +85.

Card Medic is an app that improves communication between healthcare staff and patients across any barrier, including foreign language; visual, hearing, or cognitive impairment; illiteracy; or PPE. It hosts an A-Z library of digital flashcards replicating clinical conversations around common healthcare topics; multilingual, sign language, easy read, and read-aloud. Improves quality of care, and reduces health inequalities.

WestFace Medical is a medical device company focused on enhancing vascular access procedures through innovative imaging technology. Their flagship product, SingleStick™, features a patented imaging adapter that employs optical coherence tomography (OCT) to provide real-time visualization of needle trajectories during vascular access. The system consists of a disposable handheld imaging adapter that attaches to any hollow bore needle and an OCT image processor, which displays the captured images. This technology allows clinicians to visualize anatomical markers in real-time, thereby improving clinical outcomes and patient satisfaction while potentially reducing costs associated with vascular access procedures. By offering a solution that facilitates traditional techniques with advanced imaging capabilities, WestFace Medical aims to redefine the standard of care in this critical area of healthcare.

Ronawk is a biotechnology company that specializes in the development of T-Block technology, which produces patient-specific biologics for the treatment of diseases, including cancer, organ injuries, and burns. The company has created a proprietary method for growing primary stem cells in a three-dimensional environment, allowing these cells to retain their essential characteristics outside the body. This innovative approach enables the rapid expansion of stem cells, making them suitable for early-stage diagnostics and the repair of injured tissues. Additionally, Ronawk focuses on preserving primary cells from patients for future use in reconstructive surgeries, thereby enhancing the efficiency and density of human cell growth for tissue generation and disease modeling.

Astellar Labs develops a non-invasive diagnostic technology that allows people to measure blood glucose without having to prick their fingers or wear a device that needs to be regularly swapped out, thus eliminating discomfort while also saving money.

INIA Biosciences focuses on creating non-invasive medical devices that leverage sound wave technology to manage chronic inflammatory diseases. The company's innovative system combines biomarker monitoring with an ultrasound stimulator, aimed at reducing inflammation associated with transplant rejection and decreasing reliance on immunosuppressant medications. This home-administered, closed-loop monitoring system provides physicians with advanced diagnostic capabilities to improve the treatment and prevention of organ failure, ultimately enhancing patient care in chronic disease management.

LIALT Laboratorio de Investigación Alternativa develops toxicological evaluations without the use of animals. LIALT replaces the use of animals through the use of three-dimensional tissues in conjunction with internationally recognized protocols that provide more specific information on the mechanisms of toxic action than that obtained in animals, offering a solution to the problem previously exposed.

MoviWear is a technology company that specializes in medical AI and remote monitoring solutions, primarily through its platform MoviWearMED. This platform is designed to monitor patients' vital signs in real-time, whether they are at home, in retirement facilities, or on the go. By utilizing proprietary 5G IoT NurtureWatch wearables, MoviWear can detect critical changes in health indicators such as heart rate, temperature, blood pressure, and oxygen levels, as well as alerting caregivers in case of falls. The company addresses the increasing demand for continuous health monitoring outside of traditional hospital settings, particularly for seniors. Founded in 2017, MoviWear aims to enhance patient safety and prevent health emergencies, drawing inspiration from a personal family experience. Its clientele includes health and telecommunications companies across North America, Europe, and Israel.

ModoScript develops a B2B hardware SaaS solution focused on remote treatment monitoring and big data analytics to enhance medication and treatment protocol efficiency. The company specializes in high-cost specialty pharmaceuticals, particularly Oral Oncolytics, and aims to leverage treatment progress data to create more personalized and safer therapies. By targeting pharmaceutical companies, health insurance providers, and medical practices, ModoScript facilitates the delivery of remote treatment care for patients with cancer and other chronic conditions. Their customizable data analytics model allows for real-time assessment of treatment effectiveness while ensuring that patients can access the service at no cost. Distribution partners include mail-order specialty pharmacies and in-office integrated pharmacies. ModoScript is committed to improving patient outcomes and ensuring equitable access to high-quality care, regardless of patients' backgrounds or socioeconomic status.

Lab SD offers the EYELIKE Platform which increases access to eye health services for marginalized people through appropriate technology and task-shifting. The company provides technologies that help effectively and efficiently operate international health and international development projects to eradicate poverty.

Gensor develops a virus testing platform based on the gene field-effect transistor technology.

FormaPath develops innovative laboratory tools aimed at enhancing tissue sample preparation for diagnostic purposes. The company has created an automated adipose tissue separation instrument designed to improve laboratory automation and patient care by effectively isolating lymph nodes from surrounding fat, resulting in higher yields. Additionally, FormaPath is collaborating with a prominent medical center to develop a specimen preparation system that automates the grossing process in anatomic pathology labs, thereby facilitating the detection of cancer spread. By equipping pathologists with advanced technology, FormaPath aims to provide accurate information that supports timely and reliable diagnoses for patients.

Digital Patient XP is a digital platform that reimagines the cycle of care. It provides real-time feedback on patients’ progress, recollection, engagement, and other determinants.

Lambent Data specializes in creating innovative software solutions that facilitate the engagement of families and individuals in managing their health and social determinants. The company collaborates with healthcare and social service providers to enhance outcomes and operational efficiencies. Its user-friendly platform aims to improve the well-being of children and families by addressing various social determinants of health. By leveraging powerful data analytics, Lambent Data strives to support healthcare providers and social service practitioners, ultimately leading to better health outcomes while reducing overall healthcare costs.

BestHealth4U focuses on the research and development of advanced solutions for manufacturers of class 1 medical devices. The company specializes in medical adhesive technologies that aim to prevent skin injuries, accelerate healing, and enhance overall patient health. Its innovative and environmentally friendly adhesive products are designed to safeguard patients from skin damage, discomfort, irritation, and infections by improving the attachment of bandages, dressings, and medical devices to the skin. By providing effective solutions, BestHealth4U assists healthcare providers in reducing medical adhesive-related skin injuries and promoting the well-being of patients.

Brightcure is solving the lack of treatment options available for patients suffering from recurrent urinary tract infections (UTIs). UTIs are one of world’s most common infections, affecting 50% of women and 12% of men worldwide. Current UTI treatments are not effective, can cause serious side effects, and often accelerate antibiotic-resistant infections. Total UTI costs currently amount over $ 8.6B per year. With UTI bacteria becoming increasingly difficult to treat, the size of the UTI market is expected to reach $ 12.41B by 2025. Brightcure utilizes the natural microbiome to reduce harmful bacteria and replenish the good bacteria in the vaginal flora. Brightcure’s bioactive intimate cream boosts the natural immune system to promote a healthy urinary tract. BrightCure was founded in 2019 and is headquartered in London, England. In 2020, BrightCure got a seed investment from SOSV and was selected as 1 out of 9 companies to be part of the world's largest biotech accelerator, Indiebio, to develop its first product. BrightCure has been selected as one of the Top 7 companies of the McKinsey Venture Challenge, Top 5 of the Mayor of London Competition, has won Imperial College's White City Innovation Program, and has taken part in the finals of ‘The Pitch’ London Competition being selected among 850 other applications.

Digi.Bio is a Netherlands-based company that specializes in developing software solutions for the healthcare industry, particularly in the field of cell therapies. It offers a microfluidic platform that automates repetitive and manual laboratory workflows, utilizing artificial intelligence and electrowetting technology to manipulate droplets at a microscale. This innovative approach aims to streamline multistep liquid handling applications, replacing traditional pipetting methods. Digi.Bio's platform delivers comprehensive analysis of cell therapies, evaluating their performance and outcomes at the single-cell level within 24 hours, while minimizing material waste. By enhancing automation in medical and pharmaceutical settings, Digi.Bio supports the advancement of bioengineering processes.

Criam is a biotechnology company based in Braga, Portugal, founded in 2015. It specializes in the research and development of a medical device designed for blood type analysis and the detection of infectious diseases. The company's flagship product offers rapid and accurate testing for various conditions, including HIV, Brucella, tick fever, syphilis, mononucleosis, and meningitis. This portable device operates independently of electricity or laboratory infrastructure, making it accessible for use in diverse environments. Additionally, Criam's technology is scalable, allowing a single reader to perform multiple tests using specific cartridges and advanced computer vision algorithms. By optimizing blood testing services, Criam aims to provide timely health information and improve clinical decision-making.

BioEclosion seeks to enhance user-friendly quantitative diagnostics to new molecular biomarkers for fast identification of emerging diseases that affect global health. The company started its activity with several patents, the most important being Celifast: a non-invasive approach for the detection of celiac disease. Addressing point of care attention of patients, the core technology has been successfully validated and the team is currently working on further development for commercialization.

Semantic Health is a Toronto-based healthcare technology company that utilizes proprietary artificial intelligence to enhance medical coding, auditing, and clinical documentation improvement processes for hospitals. The company's online medical data platform automates the extraction of medical codes and insights from patient charts, creating a real-time, actionable data layer. This disruptive data engine enables hospitals to analyze medical data more effectively, ultimately improving patient care, operational efficiencies, and the delivery of value-based care.

Tellus is a health monitoring platform focused on enhancing eldercare quality and operational efficiency. It utilizes advanced, wireless sensor technology to monitor vital signs and activity without the need for wearables or video cameras. The platform provides real-time alerts and actionable insights related to fall detection, sleep patterns, pulse, behavior, heart rate, and breathing rate. By analyzing baseline health data, Tellus enables care facilities to respond effectively during emergencies and make informed decisions to improve the well-being of their residents.

UpLift Health Inc., known as UpLift, is dedicated to developing a digital application aimed at treating depression through cognitive behavioral therapy (CBT). Founded in 2018 and based in Atlanta, Georgia, UpLift offers a structured program that consists of twelve weekly sessions, each lasting approximately 40 minutes. During these sessions, users engage with chatbot-guided interactions that help them learn effective coping skills. In addition to the sessions, the application provides daily tools and challenges that allow users to apply what they have learned in their everyday lives. A pilot study has demonstrated that this program can reduce symptoms of depression by 52%. UpLift's mission is to significantly impact mental health by assisting one million individuals in overcoming depression.

Ōmcare is a digital health company focused on enhancing remote care and medication adherence through its innovative IoT technologies. By collaborating with pharmacies, payers, providers, and family caregivers, Ōmcare aims to support individuals in leading healthier and more independent lives. The company's flagship product, the Ōmcare Home Health Hub, allows caregivers—including physicians, pharmacists, and family members—to remotely monitor and confirm medication administration, ensuring that patients receive the right medication at the right time. This platform also offers various call center options to maintain connections when in-person support is unavailable. By integrating remote patient monitoring and medication dispensing, Ōmcare addresses the growing demand for in-home care and telehealth services, ultimately improving health outcomes while reducing healthcare costs.

PainPal is a behavioral health platform specifically designed for individuals experiencing chronic pain. It offers a personalized and gamified approach to on-demand Cognitive Behavioral Therapy (CBT-CP), which has been shown to effectively reduce pain and enhance functioning. By utilizing this innovative telebehavioral health platform, PainPal provides a safe and evidence-based alternative for patients, addressing the growing concerns related to chronic pain management and the opioid crisis. The platform aims to redefine treatment possibilities for those suffering from chronic pain, making therapy more accessible and engaging.

See Yourself Health specializes in chronic care management by leveraging immersive technology, data science, and social learning to enhance health and wellness. The company offers a platform focused on diabetes treatment within a virtual environment, utilizing a peer network and a constructivist curriculum to foster engagement. By emphasizing peer support, online learning, and measurement-based care coaching, See Yourself Health aims to improve outcomes for individuals managing chronic diseases. Their approach is designed to help both healthcare professionals and patients navigate high-intensity, high-stress situations, thereby accelerating behavior change and optimizing health results.

Litesprite builds mobile games to help people manage health conditions like stress, anxiety/depression, diabetes or asthma. We combine proven medical treatments with the engagement of mobile games. Our mission is to create experiences that increase individual participation, incorporate support networks, and provide self-help tools so a person can easily and affordably manage their health or that of their loved ones. Clinicians and community health organizations can analyze data to understand players’ underlying triggers, communicate with players, and improve individual and group level outcomes. While we will develop a suite of games to address several health conditions, our first game SinaSprite helps the 40 million Americans, especially adult women, diagnosed with anxiety/depression. Litesprite’s innovative approach to have large scale impact in health was recognized as a winner in the Robert Wood Johnson Foundation’s 2013 Games to Generate Data Challenge. Our team includes clinicians AND gaming experts. A compelling emotional experience is the primary driver to engage and expose players to treatment methods.

Mosaic health data provides medical records of complete data of a patient's health across the continuum of care

Ōmcare is a digital health company focused on enhancing remote care and medication adherence through its innovative IoT technologies. By collaborating with pharmacies, payers, providers, and family caregivers, Ōmcare aims to support individuals in leading healthier and more independent lives. The company's flagship product, the Ōmcare Home Health Hub, allows caregivers—including physicians, pharmacists, and family members—to remotely monitor and confirm medication administration, ensuring that patients receive the right medication at the right time. This platform also offers various call center options to maintain connections when in-person support is unavailable. By integrating remote patient monitoring and medication dispensing, Ōmcare addresses the growing demand for in-home care and telehealth services, ultimately improving health outcomes while reducing healthcare costs.

Zibrio is a balance diagnostics company based in Houston, Texas, that was established in 2017. The company specializes in a technology that utilizes insights from postural control and machine learning to detect subtle changes in balance. Originally developed from NASA technology designed for astronauts returning from space, Zibrio's device aims to empower individuals to take charge of their health. By measuring balance and weight, it helps users understand their balance profiles and offers guidance for improvement. The company's mission is to enhance health outcomes, reduce the risk of falls, and promote overall balance and well-being.

Healium is a mental fitness tool that offers a drugless approach to managing anxiety, sleep, addiction, and burnout. The company utilizes patented technology that connects to biometric data from consumer wearables, such as smartwatches and EEG headbands, allowing users to monitor their brainwaves and heart rate. This information is used to create a reactive, immersive media experience that adapts to the user's bio-data. Healium's unique platform has been validated by eight peer-reviewed studies, demonstrating its effectiveness in reducing anxiety and improving mood within minutes. By leveraging existing sensors and devices, Healium provides a controlled virtual and augmented reality environment for users seeking to enhance their mental well-being.

PREEMIEr Diagnostics is a healthcare provider focused on the health of premature infants, specifically aimed at preventing retinopathy of prematurity. The company has developed a diagnostic device that measures blood glucose levels in these vulnerable patients. This technology assists healthcare professionals in identifying premature infants who require adjustments to their glucose levels, facilitating early detection of potential health issues. By improving the management of glucose levels, PREEMIEr Diagnostics contributes to enhancing the overall health outcomes for premature infants.

Decentriq is a confidential data collaboration platform designed to facilitate secure access and analysis of sensitive data while maintaining strict confidentiality. It serves both data scientists and business users, allowing them to leverage data clean rooms to analyze sensitive information without the need to share it directly. Utilizing advanced privacy technologies and hardware cryptography, Decentriq ensures that data remains encrypted throughout its lifecycle, preventing access by unauthorized parties, including cloud providers. The platform enables enterprises to scale their data collaborations across organizational boundaries, unlocking value from data that would otherwise be too sensitive to utilize. Its features support smooth collaboration workflows, flexible analysis, and interoperability with other technologies, making it particularly valuable for industries that prioritize privacy and compliance, such as media, healthcare, banking, and the public sector.

Grapheal is a Medtech startup focused on developing embedded and wearable biosensors that leverage graphene transistors for enhanced functionality. Their devices are designed to be minimalistic and digital, enabling the dosing of biomarkers and detection of pathogens through a smartphone interface. By integrating advanced sensing nanomaterials with wireless connectivity and data analysis capabilities, Grapheal's biosensors facilitate field diagnostics and remote patient monitoring. This approach aims to make healthcare more accessible and accurate, allowing medical professionals to effectively monitor patient progress and healing.

Byteflies is a Belgian-American wearable health company. Their team of medical experts, engineers, and data scientists is passionate about revolutionizing today's healthcare, one vital sign at a time. Their main office is in Antwerp (Belgium), closely located to major life sciences and clinical research centers. Their second office, located in the San Francisco Bay Area (California), operates in the heart of digital innovation.

Microbial Pulse Diagnostics is developing and deploying an innovative NIST technology for the rapid measurement of antimicrobial susceptibility. This technology “takes the pulse” of bacterial cells, sensing changes in their metabolism, motility, and growth after exposure to an effective antibiotic.

Thinks Works is an early-stage biomedical company developing ideas and products that help to solve problems that humans are dealing with. It is the concept of founder Ryan C. Murdock, MD. Through his interactions with his patients dealing with the condition of scoliosis, he saw a need for improvement in the treatment of scoliosis. He set this as a goal and now has begun to build an incredible team to bring his vision to reality so that we may dramatically improve the lives of these patients. Its device is for the non-operative treatment of adolescent scoliosis, a severe curvature of the spine in kids. Approximately 10,000 US kids per year require brace treatment. The current treatment is a custom-made hard plastic brace. It keeps the spine immobile by compressing the ribs. It has poor patient compliance and outcomes at a high patient cost. Its novel device will improve patient comfort, compliance, and outcomes at a lower total patient cost.

Pegwin is a healthcare software company that focuses on improving patient safety through its platform, KBCore. This system employs predictive technology to enhance communication among doctors, nurses, and staff while also reducing costs. Pegwin's enterprise data management platform provides real-time clinical tools that facilitate hospital rounds and offer meaningful insights for quality improvement. Additionally, it captures data to streamline risk management functions, helping healthcare organizations analyze patient safety information. By identifying active threats, Pegwin's solutions aim to predict and prevent potential harm, ultimately enabling better and safer patient care processes.

Simply Speak is a digital health company founded in 2019 and based in New York, New York. It specializes in developing an artificial intelligence platform that assists physicians in documenting telehealth encounters with patients. By leveraging conversational AI, Simply Speak's platform extracts meaningful medical data from interactions and automatically integrates this information into electronic medical records. This functionality not only streamlines the documentation process but also enhances the physician-patient relationship and boosts overall productivity within medical practices.

PROSPERiA is a social impact spinoff from the MIT Media Lab created to improve early detection and treatment of chronic diseases in emerging markets through solutions based on Artificial Intelligence

Illuminate Health App is a home health technology company. They offer advanced technology that allows them to perform a complete health exam, and encryption ensures data is protected at the highest possible levels.

Walk With Path develops wearable products aimed at improving mobility and health for patients, particularly those affected by diabetes and movement disorders. The company’s flagship offering is a smart insole equipped with biofeedback technology and sensors, designed to enhance balance and prevent complications such as foot ulcers in diabetic patients. Additionally, Walk With Path has introduced Path Finder, a specialized shoe designed for individuals with Parkinson's disease to alleviate the 'freezing of gait' phenomenon, which can leave users feeling immobilized. Path Finder is recognized as a medical device with supporting evidence published in Neurology. The company's products not only provide therapeutic benefits but also offer data insights and analytics for both end users and healthcare professionals, facilitating gait analysis and promoting better mobility in various populations.

EyeTrac has developed novel face guard technology for contact sports, which can detect concussions accurately on the field in real-time. The incidence of concussions and traumatic brain injury (TBI) has reached epidemic proportions in sports. There is a growing need on the playing field for a head-worn device that can objectively assess head trauma in real-time. This innovative technology is designed to meet the specific needs of athletes participating in contact sports and address limitations of currently available methods of evaluation. It will provide immediate accessibility with diagnostic accuracy for concussions.

UDoTest is a Boston-based B2B disease testing platform established in 2017 by Allison Martin. The company specializes in self-sampling screening test kits designed for early detection of various diseases, including colon cancer, HPV, and STDs. By offering convenient at-home testing solutions, UDoTest aims to improve the wellness experience and enhance the quality of disease screening. Its human-centered platform facilitates accurate pathology tests, allowing patients to access personalized services that simplify the screening process.

Hued is a digital health company dedicated to enhancing care quality for Black, Latinx, and Indigenous populations. It operates a health equity platform that connects underserved patients with culturally competent healthcare providers. The platform not only facilitates the search, review, and booking of appointments with providers who understand the unique physical, mental, and cultural needs of these communities, but also offers health literacy resources. Additionally, Hued assists organizations in transitioning to an equity-based care framework, aiming to address the specific healthcare needs of marginalized populations effectively.

Bloomer Tech, founded in 2015 and based in Cambridge, Massachusetts, is focused on enhancing women's health through innovative technology embedded in everyday clothing, specifically bras. The company develops fabric engineering technology that integrates biometric sensors to monitor vital health metrics, including electrocardiograms, pulse rates, respiratory rates, and heart rhythms. By leveraging machine learning and ordinary fabrics, Bloomer Tech creates a platform for personalized detection, monitoring, and treatment of chronic diseases, particularly those related to cardiovascular health. The collected data is analyzed and made accessible to users, healthcare providers, and medical professionals, fostering real-time healthcare solutions. Through its efforts, Bloomer Tech aims to build a comprehensive dataset on women’s heart health and contribute to addressing global cardiovascular health challenges.

RESUSCITECH develops a patent-pending, smartphone-based CPR feedback technology that improves outcomes in out-of-hospital cardiac arrest. This technology is used in their flagship product, SMART Certification, an app that provides CPR training and performs skills evaluation using their smartphone-based feedback technology.

Eyedea Medical is a medical company focused on advancing treatments for corneal diseases by enhancing the accessibility and effectiveness of vision-restoring corneal procedures. The company has developed a single-use graft preparation system that streamlines the processing of corneal tissue, which not only improves yields but also expands the donor pool. This innovation ensures that high-quality grafts are available for cornea transplants, allowing eye care professionals to lower costs and enhance their capacity to perform successful procedures.

Aniluxx Biotechnology, Inc. is a biopharmaceutical company focused on developing innovative topical therapeutics for companion animals, specifically targeting skin diseases such as atopic dermatitis and osteoarthritis. Founded in 2019 and located in Chapel Hill, North Carolina, the company aims to improve the health and well-being of pets by utilizing a pipeline of topically formulated therapeutics based on compounds that have demonstrated safety and efficacy in humans. These therapeutics are designed to be easy to apply and virtually unnoticeable, minimizing the harsh side effects commonly associated with systemic medications. Through its efforts, Aniluxx Biotechnology seeks to provide effective and user-friendly treatment options for dogs, cats, and horses suffering from various skin conditions.

MatchLab AI is leveraging AI technologies to increase accessibility, reduce care costs, and improve doctor correctness within Dermatology.

QRfertile LLC, based in Farmington, Connecticut, develops and manufactures a male fertility test kit that enables customers to perform tests at home. Founded in 2018, the company provides a comprehensive platform that not only allows men to assess their fertility but also connects them with physicians for guidance on improving reproductive health. QRfertile's offerings aim to make male health care more accessible and affordable, addressing a significant need in the market. By integrating modern technology with health consultations, the company enhances patient engagement and facilitates better health outcomes for men, ultimately aiming to improve their overall lifestyle and well-being.

Clara Biotech is a platform technology that allow for the isolation of specific cellular markers (exosomes) from very small fluid samples enabling liquid biopsy for the very early detection of cancer, Alzheimer's Disease and many others. These same markers can also be turned into a precision medicine drug delivery platform delivering targeted drugs directly to the cells being targeted. The current gold standard is a 12 hours ultra-centrifugation process. Ours is the only platform that can take any biofluid source, and extract any species of pure viable exosome into pure solution. We are the bridge that moves research to patient. Exosomes are one of the next major breakthroughs in Biotech. We are Clara. We are exosomes.

Eupnoos is a health-tech company specializing in digital healthcare solutions for lung health and disease detection. The company has developed a smartphone-based application that utilizes the device's microphone and camera to perform clinical-grade lung function tests and symptom-guided assessments. This platform enables users to screen, measure, and track the progression of lung health issues. By providing device-agnostic, API-accessible automated testing and data interpretation, Eupnoos supports both clinical and consumer-grade respiratory monitoring devices. The company's services facilitate telehealth and remote patient monitoring, empowering individuals to gain insights into their lung health and access professional healthcare guidance.

Dock Health is a HIPAA compliant task management and collaboration platform designed for healthcare. The company is focused on solving some of the most pressing issues in healthcare by making communication and collaboration easier through thoughtful design and simplicity. Dock is on a mission to solve the workflow challenges and inefficiencies for clinicians and their teams. Dock Health hopes to improve patient care by giving medical teams a reliable and secure system to ensure the work gets done. Founded in 2016, Dock Health is headquartered in Boston, Massachusetts.

DynamiCare Health, Inc. is a Boston-based company that offers a digital platform aimed at helping individuals reduce their use of drugs, alcohol, and tobacco. Founded in 2016, the platform integrates a smartphone application with substance testing hardware and a telehealth support system. It employs automated Contingency Management, an evidence-based approach shown to be effective in numerous clinical trials, to motivate users through positive reinforcement. Members can earn monetary rewards for maintaining sobriety, attending treatment, and completing self-guided therapy modules. The platform also features a DynamicCare Analytics portal, allowing healthcare providers to monitor participants' progress and receive real-time alerts regarding their risk levels. By combining technology with personalized support, DynamiCare Health seeks to guide individuals toward achieving healthier lifestyles.

Byteflies is a Belgian-American wearable health company. Their team of medical experts, engineers, and data scientists is passionate about revolutionizing today's healthcare, one vital sign at a time. Their main office is in Antwerp (Belgium), closely located to major life sciences and clinical research centers. Their second office, located in the San Francisco Bay Area (California), operates in the heart of digital innovation.

DynamiCare Health, Inc. is a Boston-based company that offers a digital platform aimed at helping individuals reduce their use of drugs, alcohol, and tobacco. Founded in 2016, the platform integrates a smartphone application with substance testing hardware and a telehealth support system. It employs automated Contingency Management, an evidence-based approach shown to be effective in numerous clinical trials, to motivate users through positive reinforcement. Members can earn monetary rewards for maintaining sobriety, attending treatment, and completing self-guided therapy modules. The platform also features a DynamicCare Analytics portal, allowing healthcare providers to monitor participants' progress and receive real-time alerts regarding their risk levels. By combining technology with personalized support, DynamiCare Health seeks to guide individuals toward achieving healthier lifestyles.

Health Note is an AI chatbot platform that streamlines the process of collecting patient information and creating physician notes, thereby enhancing clinic workflows. Founded in 2018 and based in San Francisco, California, the platform allows patients to engage in their own care by providing pre-visit information through a simple SMS link, eliminating the need for app downloads or sign-ins. This frictionless, platform-agnostic solution integrates seamlessly with electronic medical record systems, facilitating the documentation of physician-patient interactions and improving overall healthcare efficiency.

PXL Vision AG, founded in 2017 and headquartered in Zurich, Switzerland, specializes in the design and development of identity verification and customer onboarding software solutions. Its flagship product, Daego, employs advanced computer vision and machine learning technologies to create trusted digital identities. This cross-platform solution is tailored to meet the needs of various industries, including insurance, fintech, and healthcare, by automating the verification of identity documents and performing facial biometric checks to ensure that users are legitimate and the rightful owners of their documents. By facilitating secure and efficient customer onboarding, PXL Vision aims to enhance conversion rates, reduce costs associated with compliance, and mitigate identity fraud. With research and development centers in Novi Sad, Serbia, and Yerevan, Armenia, PXL Vision is dedicated to establishing a foundation of trust in digital interactions through unbiased and verifiable identities.

Since 2008, Emotion Food Company works to improve the lives of consumers and meet their specific needs. From conception to industrialization, through prototypes and tests, they created the Easy-Base ©, food texturizer for people with dysphagia. Because they believe that eating must remain a pleasure for everyone, regardless of their physical abilities .

Q2Q Health is a digital platform focused on preventing harmful drug reactions by providing essential health education. The company leverages data analytics to analyze user input alongside information from reputable sources, such as government databases, to identify trends and risks associated with adverse drug reactions (ADR). This approach empowers patients to make informed decisions regarding their health, helping them avoid preventable and costly medical issues. Through its innovative platform, Q2Q Health aims to enhance patient safety and promote better health outcomes.

Phylomics Diagnostics is a biotechnology company that specializes in the detection of multiple cancers.

DoorSpace is a cloud-based SaaS platform aimed at enhancing the retention and development of clinical talent within healthcare organizations. By focusing on what motivates employees to stay rather than why they leave, DoorSpace enables organizations to foster a supportive workplace. The platform streamlines workflows by reducing administrative burdens, allowing clinicians to spend more time on patient care. It offers a centralized data management system that facilitates collaboration and real-time updates of critical personnel information, such as licensure and certifications. This ensures that healthcare leaders have the insights needed for informed decision-making, significantly improving operational efficiency. Furthermore, DoorSpace addresses common pain points, such as delays in staffing processes, inefficiencies in reporting, and the inability to quickly assess clinician strengths and weaknesses. By automating back-office tasks and providing transparency across the workforce, DoorSpace helps organizations optimize their resources, enhance employee satisfaction, and ultimately improve patient care outcomes.

Miraqules is a healthcare company that provides care medical solutions and introduced StopBleed.

Detectan is a medical innovation company for diagnostics.

OrthoBistro has designed a new platform in orthopedic healthcare that enables meaningful and effective patient interactions with doctors. Their team provides patient education, telemedicine, and physical therapy tools that fit your lifestyle.

S-There is a company that has developed an innovative smart toilet device aimed at improving health monitoring. This passive medical device allows users to track their hydration levels and understand how environmental factors impact their hydration. Through a mobile application, S-There provides users with detailed insights into their hydration quality and trends, enabling them to make informed decisions about their health. By offering personalized feedback, the device aims to assist individuals in managing their hydration effectively and addressing chronic health issues.

Everyplace Labs is focused on creating a self-service kiosk that automates point-of-care testing, specifically for urine diagnostics. This innovative platform integrates add-on devices with toilets to facilitate the entire process from specimen collection to result delivery. By enabling patient-initiated or staff-assisted testing at intake or triage in acute care environments, Everyplace Labs aims to eliminate bottlenecks, enhance throughput, and improve the efficiency and accuracy of data collection. Additionally, the solution promotes a more hygienic and comfortable experience for patients while reducing the need for clinical staff involvement.

Genetrainer is a website that provides a personalized fitness plan for users based on their genes. Genetrainer provides online training plans, exercises and advice personalized to the user by using their DNA, thus helping them to find the fastest route to achieving their individual training goals. Genetrainer stays up to date with the user's fitness level through connection to a range of popular devices and apps, combining lifestyle and genetics to give you the fastest route to achieving your individual training goals.

CareZooming provides a means to spread healthcare improvement knowledge and build community. They join in lowering the barriers to implementing innovations in care delivery.

Annaida Technologies has developed a groundbreaking device, EmbryoSpin, that performs microscopic Nuclear Magnetic Resonance (“µNMR”) at a scale 10-fold better than existing technologies.

Dyad Medical Inc. is a company that specializes in developing a cloud-based platform for automated analysis and interpretation of cardiac and cardiovascular images. Founded in 2018 and headquartered in Allston, Massachusetts, its software enhances the assessment of heart anatomy and physiology, facilitating rapid diagnosis and patient triage. The platform supports heart characterization using Magnetic Resonance Imaging (MRI), analyzes intravascular images to evaluate plaque content and stent deployment quality, and automates valve sizing for percutaneous aortic valve replacement. By integrating machine learning and advanced analytics, Dyad Medical's solutions assist healthcare professionals in making informed treatment decisions in clinical settings and contribute to research efforts by optimizing observations and conclusions.

Clemedi AG develops innovative diagnostic workflows for infectious diseases, focusing on in vitro diagnostic tests that leverage next-generation sequencing and machine learning technologies. Established in 2018 and headquartered in Schlieren, Switzerland, the company aims to combat antibiotic resistance, which is projected to cause 10 million deaths annually by 2050. Clemedi's test kits are designed to diagnose drug-resistant infections directly from patient samples within a day, thereby enhancing doctors' decision-making and facilitating timely, personalized antibiotic therapies. By providing comprehensive information for targeted treatment, Clemedi strives to reduce antibiotic consumption and slow the spread of resistance, ultimately benefiting patients suffering from infectious diseases.

KJ scientific ensures testing and analysis of chemicals product to safety for human and environmental health.

MedicSen is a start-up dedicated to health care, to technological innovation as a key tool. With several projects under mind, we have launched the most ambitious of them all, GlycSen. It is designed for intelligent treatment of insulin dependent diabetes device.

G. Root Biomedical is a testing reports service center focused on assisting cancer patients in identifying personalized treatment options based on their genetic mutations. The company offers access to extensive biological, medical, and pharmacological information, drawing from major scientific journals and academic publications. Utilizing an artificial intelligence algorithm, G. Root Biomedical enhances the process of uncovering tailored medicines, aiming to facilitate quicker healing for patients.

Twistle, Inc. operates a patient engagement platform designed to enhance communication between healthcare providers and patients, facilitating faster recovery. Founded in 2011 and headquartered in Seattle, Washington, the platform automates care plan management by monitoring patient care pathways and engaging healthcare teams only when necessary. It offers tools for secure automated messaging, photo and lab sharing, surveys, and integration with electronic health records (EHRs) and smart devices. By enabling medical practitioners to efficiently collect patient data and respond to concerns, Twistle aims to improve patient outcomes, reduce healthcare costs, and streamline clinical workflows. The company was initially incorporated in 2010 and has since focused on delivering a comprehensive solution for personalized patient engagement.

Valera Health, established in 2015, operates a behavioral healthcare platform focused on delivering personalized mental health services to individuals with a range of conditions from mild to severe, including depression and schizophrenia. The company integrates digital technology and data science with traditional clinical services to enhance patient outcomes and address the needs of hard-to-reach populations. By providing a comprehensive approach that combines therapy, medication, and continuous connectivity with care teams, Valera Health aims to offer efficient mental healthcare solutions, particularly for employers seeking to improve access to mental health support for their employees.

Multisensor Diagnostics (MDx), LLC, is a diversified health and wellness company primarily serving the high-acuity patients.

Lumme Health, Inc. develops smartwatch-based behavior change software for smoking cessation and weight management. For such high-frequency behaviors, Lumme's machine learning apps, which run continuously in the background of a smartwatch, eliminate the burden of tedious self-monitoring by passively tracking real-time, objective consumption metrics and behavioral patterns from the motions of the hand. This dramatically increases self-awareness and understanding over traditional, manual reporting methods, and uncovers insights and triggers that lead to problematic habit loops. Lumme further combines decades of clinically-validated research in behavioral psychology with predictive analytics to identify exactly when and how users should focus their efforts to achieve the greatest possible success.