MassChallenge

Founded in 2021, Sóliome is a biotechnology company based in San Francisco, California. It specializes in developing protein-based sunscreens that are safe and effective, using molecules naturally produced by the human body to protect against harmful UV rays.

Seprify develops and sells cellulose-based white pigments and opacifiers, aiming to replace titanium dioxide in various industries. Their plant-derived solutions are renewable, biocompatible, and scalable, promoting sustainability and safety in product manufacturing.

Seprify develops and sells cellulose-based white pigments and opacifiers, aiming to replace titanium dioxide in various industries. Their plant-derived solutions are renewable, biocompatible, and scalable, promoting sustainability and safety in product manufacturing.

Kura Skin is a skincare matchmaking platform. We use data and our proprietary matchmaking algorithm to help our customers cut through the clutter and find what works for a fraction of the cost and none of the hassle.

Hue Beauty is a beauty technology and sampling platform designed to assist beauty shoppers in identifying makeup products that complement their unique skin tones. The platform integrates with beauty brands' e-commerce websites, utilizing photo technology and a community of beauty advisors to facilitate accurate shade matching. Additionally, Hue Beauty offers customized try-at-home shade sampling kits, enhancing the shopping experience. The company also develops shoppable video technology, allowing online beauty brands to incorporate user-generated videos into their marketing strategies. This approach fosters customer trust and engagement by providing authentic content. Moreover, Hue Beauty employs an artificial intelligence-powered recommendation engine to analyze shoppers' skin tones, types, and beauty preferences, enabling clients to generate genuine reviews in various formats.

Nul is a not-just-for-profit company with the mission to make the personal and household care industry more sustainable by offering eco-friendly alternatives that actually work. No water. No plastic. No toxins. No nonsense. Nul believe in giving back; pledging 1% of all sales to environmental charities as a member of 1% for the Planet.

Michroma is a biotech company that develops natural, thermostable colorants for fungus-based food and cosmetics by leveraging fermentation of filamentous fungi and synthetic biology. It aims to replace synthetic pigments with natural pigments produced through biotechnological fermentation, delivering pH- and heat-stable colorants at scale for food and cosmetic applications. The company operates in multiple locations, including San Francisco, United States, and Rosario, Argentina, and pursues scalable production in bioreactors using proprietary fungal strains.

Naturbeads Ltd., established in 2018 and headquartered in Malmesbury, UK, specializes in manufacturing biodegradable cellulose microparticles. These products aim to replace conventional plastic microbeads used in cosmetics, toiletries, and other industries. The company's mission is to mitigate microplastic pollution by offering a sustainable alternative developed through innovative research at the University of Bath.

Rayito de Luna is a Mexican company that develops beauty and personal care products for women and men. It is an eco-friendly 100% natural personal care brand, that practices fair trade and supports the development of local independent producers.

Renzoe Box is a beauty platform that streamlines personal makeup collection through its hardware and software. It offers a compact storage system designed to accommodate various makeup products, enabling users to create their own palette and carry all essentials in one easy-to-manage box.

Upwell’s is a cosmetic industry provides patented algae wax with safe ingredients.

Bellezacheck is the 'Tripadvisor' of beauty product and that provides consumer reviews&ratings on website.

Aisling Organics is an innovative company specializing in high-performance organic makeup and natural skincare products. Founded by Krysta Lewis, the company emerged from her personal health struggles linked to conventional cosmetics, which prompted her to seek safer alternatives. Aisling offers a diverse range of products, including concealer, liquid foundation, eyeshadow, lip gloss, and mascara, all formulated from crushed plants and herbs. The company’s mission is to provide consumers with skin-friendly options that do not compromise on efficacy or longevity, allowing individuals to prioritize both health and beauty. Aisling's products are available through its e-commerce platform, catering to a growing demand for clean cosmetics.

Founded in 2016, ZeoVation specializes in manufacturing nanozeolites and hierarchical zeolites. These materials enhance consumer products such as skincare lotions, sunscreens, laundry detergents, water softeners, and filtration systems by improving efficiency.

Microcaps develops microencapsulation technology that protects and controls the release of active ingredients in pharmaceuticals, probiotics, and cosmetic formulations. Leveraging microfluidics and step emulsification, the company produces monodisperse microcapsules and microparticles at scale, enabling precise size control, dosing, and greater stability. Its platform supports liquid oil core microcapsules with natural alginate shells, improving throughput without quality loss. Based in Zurich, Switzerland, Microcaps targets applications across drug delivery, probiotic encapsulation, and fragrance or cosmetic encapsulation, offering automated encapsulation production capable of high-throughput manufacturing for complex formulations.

Nagi Bioscience develops automated testing devices that use Caenorhabditis elegans worms to screen molecules for pharmaceutical, chemical and cosmetic applications. Its Organism-on-Chip platform combines whole-organism biology with an automated in vitro workflow for culture, treatment, and multi-parametric analysis, enabling toxicity testing, drug discovery, and anthelmintic screening. The technology links in vivo worm models with a fully automated platform to observe biological responses that emerge at the whole-organism level. The company is headquartered in Lausanne, Switzerland.

SoaPen is a cosmetics firm established in 2016 by Amanat Anand and Shubham Issar, specializing in handmade soap products designed specifically for children. The company produces roll-on soap bottles that aim to encourage good hygiene habits among kids through engaging and playful designs. SoaPen's soaps are formulated to be non-irritating, non-toxic, and free from harmful ingredients such as SLS, parabens, and phthalates, as well as any animal by-products. By offering a fun way for children to wash their hands, SoaPen promotes personal hygiene in an enjoyable manner.

ApreX Biotech is a developer of advanced organs-on-chips systems aimed at transforming pharmaceutical development and personalized medicine. The company specializes in utilizing innovative origami folding techniques to create intricate 3D tissue architectures from simple, easily manufactured 2D patterns. This technology enables ApreX Biotech to facilitate the advancement of products across various sectors, including pharmaceuticals, chemicals, food, and cosmetics. By providing a cutting-edge platform for in vitro testing, ApreX Biotech supports clients in developing more effective and tailored solutions in their respective industries.

KUSHAE offers feminine personal care items. They provide a wide range of goods, including spray, body wash, lotions, and more. They also provide free shipping on orders of $60 or more.

SunZee is an innovative company focused on revolutionizing sun protection through its unique sunscreen delivery system. The company has developed a patent-pending capsule that allows users to extract a measured amount of sunscreen directly onto their fingertips with a simple one-handed motion. This system is integrated into a fashionable wristband, making sun protection both accessible and convenient for users, particularly children. By addressing the evolving needs of consumers and enhancing awareness of sun damage, SunZee aims to transform how individuals engage with sunscreen, promoting better habits for sun safety in everyday life.

Orchid Green has developed the natural compound AAPE1, which is an anti-aging antioxidant for skin. AAPE1 is chemically stable, resistant under high and low temperatures, and keeps its effectiveness over time. AAPE is water soluble and inhibits wrinkle formation.

Giaran, Inc. is a technology company based in Brookline, Massachusetts, specializing in software that enhances the cosmetic shopping experience through virtual try-on solutions. Founded in 2016, Giaran offers an innovative online application that employs artificial intelligence and augmented reality to enable users to virtually sample makeup products in real-time, whether in-store, online, or on-the-go. The company's technology focuses on providing precise color matching for cosmetic products, enhancing consumer engagement and personalization in the beauty industry. As of November 2017, Giaran operates as a subsidiary of Shiseido Americas Corporation.

Kreyol Essence is an agribusiness that specializes in providing affordable luxury beauty products sourced from organic commodities in Haiti. Known for its commitment to being "natural with a purpose," the company focuses on empowering women by addressing various skin flaws while simultaneously creating employment opportunities for 400 local women and farmers. Kreyol Essence aims to enhance environmental, agricultural, and economic conditions in Haiti, positioning itself as a model for addressing complex social issues through sustainable business practices. By offering quality beauty products, the company not only promotes personal wellness but also supports local artisans and cultivates a positive impact on the community.

Ingredio offers a mobile application that enables users to scan product ingredient labels. It then provides information on whether these ingredients are safe, toxic/allergenic, or of natural origin based on verified chemical databases. This service empowers consumers to make informed decisions about the products they use.

Biomicrogels Group develops biomicrogels, a substance derived from agricultural waste like sugar beet and apple pomace. This unique material addresses global environmental challenges by treating produced water, separating cutting fluids, extracting vegetable oils, and cleaning oil spills. The company also produces eco-friendly household cleaning products under the WONDERLAB brand.

MesenFlow Technologies specializes in innovative bio-imaging technology aimed at enhancing drug and cosmetic development. The company’s platform addresses critical challenges in modern drug development, including species cross-reactivity and the ethical concerns of animal testing. By utilizing proprietary protocols on primary human cells, MesenFlow enables early definition of a drug's mechanism of action and its relevance to human biology. This approach not only accelerates the pharmaceutical testing process but also extends to the cosmetics and nutraceutical sectors, allowing for the assessment of product safety and efficacy at an early stage. MesenFlow's technology is particularly beneficial for organizations requiring animal-free testing solutions, ensuring compliance with regulatory demands while prioritizing human biological impact.

Ecoflora Cares develops natural color technologies for the food and personal care industries. It provides custom development and advisory services to help clients transition from synthetic to natural colorants, and conducts testing of color properties such as solubility, stability, precipitation, and concentration in food applications, ensuring compatibility with industrial processes. Founded in 1988 and based in Sabaneta, Colombia.

Flying Spark Ltd, established in 2014 and headquartered in Ramat Gan, Israel, specializes in the production of protein powder derived from fruit fly larvae. The company's primary products are dietary protein whole powder, reduced fat powder, and oil, all of which are rich in essential nutrients like iron, calcium, magnesium, and dietary fibers, as well as amino acids. These products cater to various industries, including food and feed for human consumption, and cosmetics, due to their white color, mild taste, and aroma, which facilitate easy incorporation into diverse applications.

Eyedoll Chatter is an application that offers scented eyeshadows, face shimmers, and lip glosses.