MassChallenge is a global nonprofit startup accelerator headquartered in Boston, Massachusetts, founded in 2009. It supports early-stage entrepreneurs from various industries, including technology, healthcare, and finance, by providing mentorship, resources, and networking opportunities. With locations in countries such as Israel, Mexico, Switzerland, and Texas, MassChallenge operates a non-equity model, allowing startups to retain full ownership while benefiting from expert guidance and connections. The accelerator conducts various programs tailored to specific sectors, such as MassChallenge HealthTech and MassChallenge FinTech, which facilitate partnerships between startups and established enterprises to drive innovation and market growth. Through its extensive global network, MassChallenge aims to strengthen the innovation ecosystem and empower high-potential startups to create meaningful impact.
MoviWear is a technology company that specializes in medical AI and remote monitoring solutions, primarily through its platform MoviWearMED. This platform is designed to monitor patients' vital signs in real-time, whether they are at home, in retirement facilities, or on the go. By utilizing proprietary 5G IoT NurtureWatch wearables, MoviWear can detect critical changes in health indicators such as heart rate, temperature, blood pressure, and oxygen levels, as well as alerting caregivers in case of falls. The company addresses the increasing demand for continuous health monitoring outside of traditional hospital settings, particularly for seniors. Founded in 2017, MoviWear aims to enhance patient safety and prevent health emergencies, drawing inspiration from a personal family experience. Its clientele includes health and telecommunications companies across North America, Europe, and Israel.
PickApp Farming
Pre Seed Round in 2021
PickApp leverages labor-activity data to help farms reach peak performance. Our innovative farm-activity data collection methods and user-friendly intelligent-farming tools are introducing data-driven super-powers to the real-time management and high-level decision making of any farm.
Serenno Medical
Non Equity Assistance in 2021
Serenno Medical is a medical device company based in Yokneam Illit, Israel, founded in 2017. The company specializes in developing a urine output measuring device designed for use in intensive care units (ICUs). Its flagship product, the Sentinel device, provides accurate, automatic, and continuous monitoring of urine output, enabling healthcare providers to detect and assess the risk of acute kidney injury (AKI) in hospitalized patients. This technology enhances patient safety while reducing the workload for medical staff and lowering costs associated with patient care. By offering real-time data on kidney function, Serenno Medical aims to improve fluid management and facilitate early intervention, ultimately helping to prevent severe kidney damage and reduce hospital stays.
SafeUP - Women's Safety Net
Non Equity Assistance in 2021
90 days from launch (Dec 20): - 4 paying clients in 90 days, 25 days sales cycle. - 10,000 users covering all 10 largest cities of Israel. Together with our SafeUPer we - Create a Safe World for Women - One community at a time. Create – We believe people must take an action, getting out of our comfort zone, to achieve this change. Sharing stories is simply not enough. Safe – We believe being safe is a basic right of all women, and like all women right achieved by previous generations, it will be gained with sweat and tears. World – We are facing a global problem, documented for at least two millennia (2,000 yrs), maybe the only problem impacting women daily, of all ages, countries, backgrounds and beliefs. Therefore. We believe it should be solved globally, empowering women all around the world to bring safety to their local communities. Women – We believe that when women will have peace, men too will have peace. Men have proven that they are unable to bring peace and safety by themselves to themselves nor to women. Therefore, we need to lead and bring it together.
PickApp Farming
Non Equity Assistance in 2021
PickApp leverages labor-activity data to help farms reach peak performance. Our innovative farm-activity data collection methods and user-friendly intelligent-farming tools are introducing data-driven super-powers to the real-time management and high-level decision making of any farm.
Xeye.ai
Grant in 2020
Xeye.ai, a company founded in 2015 and based in Haifa, Israel, specializes in developing advanced weapon detection technology. It utilizes innovative near-field electromagnetic imaging and artificial intelligence to provide real-time threat detection in crowded public spaces. The company's Near Field Threat Detection (NFTD) system is designed to identify concealed weapons without interrupting the flow of foot traffic, making it suitable for high-traffic areas such as transportation hubs, stadiums, casinos, hotels, mass events, and campuses. Xeye.ai aims to enhance public safety while maintaining individual privacy and convenience, positioning itself to transform traditional scanning methods in security applications.
Xeye.ai
Pre Seed Round in 2020
Xeye.ai, a company founded in 2015 and based in Haifa, Israel, specializes in developing advanced weapon detection technology. It utilizes innovative near-field electromagnetic imaging and artificial intelligence to provide real-time threat detection in crowded public spaces. The company's Near Field Threat Detection (NFTD) system is designed to identify concealed weapons without interrupting the flow of foot traffic, making it suitable for high-traffic areas such as transportation hubs, stadiums, casinos, hotels, mass events, and campuses. Xeye.ai aims to enhance public safety while maintaining individual privacy and convenience, positioning itself to transform traditional scanning methods in security applications.
MyPart
Grant in 2019
MyPart Ltd is an artificial intelligence company based in Tel Aviv, Israel, that develops an innovative platform designed to enhance song discovery for various industries, including music, television, film, and advertising. Its award-winning technology utilizes reference songs instead of traditional tagging methods, allowing music and creative executives to search and prioritize their catalogs more effectively. By analyzing songs submitted by emerging songwriters, MyPart ensures that opportunities are matched based on relevance rather than personal connections, thus democratizing access to the industry. The platform's proprietary 'Song Mining' engine performs a detailed analysis of musical and lyrical elements, employing machine learning and digital signal processing to find songs that share common features with established benchmarks. This approach not only aids industry decision-makers in discovering new talent but also emphasizes the importance of song semantics and aesthetics. MyPart has participated in prestigious programs such as Universal Music's Abbey Road RED and Capitol Records' gBeta, and it has received accolades including the MassChallenge 2018 gold award.
Butterfly Medical
Grant in 2019
Butterfly Medical Ltd is a medical device company based in Yokne'am, Israel, founded in 2014. The company specializes in developing an innovative implantable device designed to treat Benign Prostatic Hyperplasia (BPH), commonly known as enlarged prostate. This device offers a fast, simple, and minimally invasive alternative to conventional BPH treatments, such as medication and surgery. It can be placed in under ten minutes in an office setting, using local anesthesia and without the need for surgical incisions or tissue removal. This approach aims to provide a long-term solution with minimal side effects, eliminating the need for hospitalization or general anesthesia. Early clinical trials have shown promising results, with effective outcomes in relieving blocked urethras and no reported side effects. Butterfly Medical is advancing further clinical studies at leading medical centers in Europe to validate its device's efficacy and safety.
NeuroApplied
Non Equity Assistance in 2019
NeuroApplied Ltd. is a marketing research company based in Hadera, Israel, founded in June 2016. The firm specializes in customer-focused marketing by exploring the collective subconscious of consumers. Utilizing machine-learning analytics and neural-network computing, NeuroApplied's platform incorporates online picture games to collect data that reflects customers' associative subconscious responses. This SaaS-based platform features an intuitive dashboard that presents insights in a visually engaging and nonintrusive manner. The services offered include brand equity assessment, tracking of brand properties, crisis management, and decision support, all designed to help brand managers understand and quantify consumer perceptions effectively.
Lingopie
Non Equity Assistance in 2019
Lingopie Inc. operates an innovative language learning platform that uniquely combines television shows and movies with language acquisition technology. Founded in 2018 and based in Tel Aviv, Israel, Lingopie offers users access to thousands of hours of foreign content, enabling them to learn languages in an engaging manner. The platform features episodes displayed with native subtitles, allowing learners to click on foreign words for instant translations, which are then stored in a personal word bank for review through a flashcard game and other interactive tools. This approach leverages natural-language processing and linguistic research to create an immersive learning experience, making language acquisition intuitive and enjoyable for users.
Climber
Non Equity Assistance in 2019
Climber is an Israeli company established in 2016, specializing in the manufacturing of home escalators. Its product is designed to assist individuals who face challenges with climbing or descending stairs, particularly older adults and those with disabilities. By providing a safe and reliable means of navigating stairwells, Climber aims to reduce the risk of falls and enhance the quality of life for its users, allowing them to maintain their independence and comfort within their own homes.
ATLASense Biomed
Non Equity Assistance in 2019
ATLASense Biomed, founded in 2015 and based in Israel, specializes in innovative medical devices for remote patient monitoring. Its flagship product, the PolyMonitor, is a chest-worn device designed to provide early detection of respiratory and cardiovascular deterioration, addressing critical gaps in current healthcare monitoring systems. During the COVID-19 pandemic, it became evident that many patients experienced sudden respiratory failure, often leading to costly and invasive interventions. ATLASense's technology enables healthcare providers to identify the early stages of respiratory decline, potentially preventing emergencies such as intubation and mechanical ventilation. The company’s REPHAEL platform employs AI-based algorithms to facilitate real-time health monitoring, allowing for timely interventions that improve patient outcomes and reduce costs. Targeting a global market of over one billion people, ATLASense offers its subscription service at an affordable rate, aiming to enhance preventive care and optimize healthcare delivery, particularly in underserved areas.
OtailO
Non Equity Assistance in 2019
OtailO is a company that offers a smart and sustainable solution for managing online product returns. Founded in 2019 and based in Ramat Hasharon, Israel, OtailO employs an AI and data-driven platform designed for enterprise retailers. The system calculates the optimal shelf for each return in real time and facilitates dynamic routing to that location. Key features include remote inspection to verify the condition of returns and the transformation of authorized partners into local reselling, recycling, refurbishing, and donation points. This approach minimizes logistical costs, reduces carbon emissions, and addresses returns-related fraud while enhancing customer loyalty by improving the overall post-purchase experience. By connecting online and offline retailers, OtailO creates a more efficient returns process that benefits both retailers and consumers.
GammaSeed
Non Equity Assistance in 2019
GammaSeed is an agriculture company based in Nir Galim, Israel, specializing in seed genetic sorting and purity screening. Founded by Itay Yogev, the company provides innovative seed analysis solutions aimed at enhancing seed quality, purity, and health. GammaSeed offers a fast, cost-effective, and non-destructive seed sorting service that employs advanced computer vision and artificial intelligence algorithms. This technology ensures that disqualified seed batches are upgraded to meet desired commercial standards, allowing farmers to improve their profitability through enhanced seed screening processes.
FanFund
Non Equity Assistance in 2019
FanFund makes culture accessible to communities everywhere by de-risking live shows for artists and venues. It integrates fan engagement, crowdfunding technologies with advanced data analysis to provide artists and venues with vertical and geographic-specific predictive models for de-risking live performances. The company was founded in 2017 and is headquartered in Tel Aviv, Israel.
Solutum
Grant in 2018
Solutum Ltd., founded in 2017 and based in Tel Aviv-Yafo, Israel, specializes in the development of biodegradable products that serve as an alternative to traditional plastics. The company has created a unique formula that allows its plastic bags to dissolve in water, turning into natural and eco-friendly components. This innovation addresses the significant environmental challenges posed by plastic pollution, which contributes to the annual production of approximately 350 million tons of plastic, much of which consists of single-use items that severely impact land and marine ecosystems. Solutum's products, developed by a team of chemical engineers, aim to provide a cost-effective solution to this global issue, while also mitigating the substantial social and environmental costs associated with plastic waste, estimated at $139 billion each year. Through its biodegradable offerings, Solutum seeks to promote sustainability and reduce the harmful effects of plastic on health and the environment.
Dermafence
Non Equity Assistance in 2018
Dermafence is a medical technology company founded in 2017 and based in Jerusalem, Israel. It specializes in developing innovative products for the treatment of energy-mediated skin injuries and burns. The company's flagship offerings consist of liquid bandages that create a protective layer on the skin upon application. These devices effectively prevent the progression of wounds caused by various types of energy absorption, including thermal, mechanical, radiation, and laser-induced injuries. By providing an incision-less and scar-free healing process, Dermafence aims to enhance recovery outcomes for individuals suffering from such skin injuries.
RouteValet
Non Equity Assistance in 2018
RouteValet specializes in developing advanced route planning technology designed for mobility companies. Its innovative platform combines various transportation options, including both public and private transit, to provide users with the fastest and most cost-effective routes to their destinations. The company's goal is to license this technology to transportation providers and establish a mobility marketplace. RouteValet has garnered recognition for its achievements, winning awards from MassChallenge and international competitions sponsored by major corporations. Furthermore, its multimodal algorithms have been reviewed and funded by the Israel Innovation Authority. A successful paid proof of concept conducted in Japan demonstrated the effectiveness of RouteValet's solutions, enabling commuters to save an average of one hour per day and increasing user satisfaction with their transit options by 26%.
Sindesy
Non Equity Assistance in 2018
Sindesy transforms the water heating business and its value chain, using unique and patented sensor deployment technology. The company's technology enables customers to control their water heater, be constantly connected, and instantly cared for. Sindesy was founded in 2016 and is headquartered in Israel.
Make My Day
Non Equity Assistance in 2018
Make My Day offers an in-car driving assistance app for optimizing driving in electric cars. Its features for an in car Driving Assistance connects the driver with the car while doing extra activities. It also connects drivers to business providers and gives them a full range solution for the daily needs. Make My Day is based in Tel-Aviv, Israel.
S.R.I
Non Equity Assistance in 2018
S.R.I specializes in providing traffic and highway engineering solutions. The company was founded in 2013 and is headquartered in Hertzlia, Israel.
Brightmerge
Non Equity Assistance in 2018
Brightmerge Ltd. is a company that develops an enterprise SaaS platform designed to optimize renewable energy microgrids. Founded in 2018 and based in Tel Aviv-Yafo, Israel, Brightmerge offers an AI-driven suite of products tailored for microgrid developers, financial experts, and energy operators. The platform utilizes proprietary machine learning and big data solutions to automate tasks typically performed manually by project developers and engineers, thereby streamlining the design and operation of microgrid systems. Brightmerge's tools aim to enhance performance prediction, risk mitigation, and overall cost-effectiveness, facilitating the transition to more complex energy networks. The company's focus is on addressing the evolving needs of the energy sector as it adapts to new technologies and business models, ultimately supporting the future of dynamic energy systems.
Air Doctor
Non Equity Assistance in 2018
Air Doctor Ltd. operates an online marketplace that connects travelers with verified medical practitioners, facilitating access to healthcare services while abroad. Founded in 2016 and based in Motza Illit, Israel, the platform enables users to search for and book appointments with a variety of healthcare providers, including doctors, dentists, emergency clinics, pharmacies, and laboratories. It features profiles of practitioners along with patient reviews, allowing travelers to select professionals who meet their specific needs and speak their language. By streamlining the process of obtaining medical care in unfamiliar locations, Air Doctor enhances the travel experience for individuals seeking healthcare services.
RePark Social Parking
Grant in 2017
RePark Social Parking is a mobile application service that facilitates the rental of private parking spaces by the hour. Launched in 2014 in Tel Aviv, Israel, the platform connects parking space owners with drivers in need of parking, providing a convenient solution for urban parking challenges. Through the app, users can easily list their available parking spaces, while drivers can search for and reserve these spaces, enhancing accessibility and efficiency in urban environments.
Sonovia
Grant in 2017
Sonovia Ltd. is an Israeli company specializing in the production of ultrasonic coatings for textiles, aimed at creating anti-bacterial and odorless fabrics. Founded in 2013 and formerly known as Nano-Textile Ltd., the company developed a unique sono-coating process that leverages cavitation, allowing for a highly effective and environmentally friendly application without the use of chemical binders. This innovative technology is applied to various textiles used in hotels, restaurants, hospitals, and clothing, including patient gowns and bedding. Additionally, Sonovia manufactures reusable masks in response to the COVID-19 pandemic. The company is headquartered in Ramat Gan, Israel.
Extreme Simulations
Grant in 2017
Extreme Simulations is an independent provider of advanced simulation products and training platforms focused on emergency situations. The company specializes in developing high-end medical simulators that are durable, realistic, and user-friendly. Its innovative technology includes a multi-purpose physical simulation platform that features a blood pump system and simulation blood, all controllable via an app. This platform aims to reduce preventable death rates in healthcare by enabling real-time error identification and data analytics. Additionally, Extreme Simulations serves as the official medical simulation instructor for the Israeli Defense Forces, training over 100,000 combat soldiers annually. The company's commitment to enhancing the skills of medical and security professionals positions it as a leader in the field of simulation-based training.
C2A Security
Grant in 2017
C2A Security Ltd. specializes in developing cybersecurity solutions tailored for the automotive and trucking industries. Founded in 2016 and based in Jerusalem, Israel, the company offers a comprehensive platform that addresses the unique cybersecurity needs of car manufacturers and mobility companies. Its product suite includes advanced tools for detecting and mitigating cyber-attacks, ensuring the protection of vehicle internal systems against various threats, including those targeting autonomous systems and hardware vulnerabilities. C2A Security aims to enhance the value of cybersecurity through automation and compliance, streamlining software release processes while reducing costs associated with managing automotive software products.
Inka Robotics
Non Equity Assistance in 2017
Inka Robotics is a special and promising startup from Israel aiming to disrupt the booming tattoo industry by revolutionizing its technology. Briefly, Inka Robotics is building a tattooing robot controlled by computer vision. The robot can tattoo any type of tattoo, including remarkable tattoo designs and reproductions designed by the best artists in the world.
XRHealth
Non Equity Assistance in 2017
XRHealth Ltd. is a medical technology company that specializes in developing virtual reality (VR) and augmented reality (AR) solutions for therapeutic applications. Based in Tel Aviv, Israel, XRHealth creates a range of software platforms designed to enhance patient care and address various health-related challenges. Its offerings include VRPhysio for virtual physical therapy, VRReliever for pain management, VRCogni for improving motor function in stroke and dementia patients, and VRPsyc for exposure therapy targeting mental health disorders. Additionally, VRCoordi focuses on improving coordination skills for individuals with conditions such as Parkinson's disease and autism. By integrating immersive technologies, licensed clinicians, and advanced data analytics, XRHealth provides comprehensive telehealth services, enabling patients to receive effective treatment from the comfort of their homes. Founded in 2016, the company aims to innovate healthcare delivery for patients, clinicians, and healthcare professionals alike.
Paygilant
Grant in 2016
Paygilant Ltd. is a developer of mobile fraud prevention solutions, focusing on online transactions, payments, and money transfer fraud. Founded in 2014 and based in Ramat Gan, Israel, the company addresses the rising challenge of mobile fraud as the adoption of mobile payments increases. Paygilant offers a comprehensive suite of services, including account takeover prevention, new account fraud solutions, and transactional fraud protection. Its patented technology integrates six proprietary intelligence sets to ensure a frictionless user experience while maintaining security and user privacy. The company’s solutions provide end-to-end protection, from app download to ongoing transactions, effectively safeguarding legitimate customers against fraudulent activities in the evolving digital payment landscape.
PrintCB
Grant in 2016
PrintCB Ltd., located in Ness Ziona, Israel, specializes in the manufacture of copper inks designed for printed electronics. These inks aim to replace silver, the most expensive component currently used in the industry, thereby significantly reducing manufacturing costs in a market valued at $70 billion. PrintCB's innovative copper inks are compatible with standard printing processes and do not require changes to existing capital equipment. They can be cured in ambient air using conventional conveyor or box ovens, making them versatile for various applications, including circuitry, sensors, and energy devices. This flexibility allows printing industries to utilize non-brand-specific inks compatible with different dispensing systems, promoting efficiency and cost-effectiveness in production.
RUSTYS
Grant in 2016
RUSTYS is an Israeli healthy lifestyle bringing mindful snacking to the local market without compromising on taste. RUSTYS Nut Butters & Treats is a local Israeli healthy lifestyle brand giving the local market the ability to eat healthy without having to compromise on taste. They use locally sourced nuts to help promote local agriculture and combine them with organic flavors from around the globe such as Canadian maple syrup to create the most delicious nut butter spreads. Their online presence, community events and recipes they share with their audience help Israelis live healthier more active lives.
NrgStorEdge
Grant in 2016
NrgStorEdge Ltd is a start-up, based on patented energy storage technology for safe and inexpensive use in zero-emission hydrogen-powered vehicles. NrgStorEdge is located in the Hi-Tech Village of Jerusalem, Israel. They are approved and financially supported by the Israeli Government and Jerusalem Development Authority.
Cnature
Grant in 2016
Cnature is a social enterprise based in Tel Aviv, Israel, founded in 2017, that has developed a mobile application for real-time identification of plants and animals. Users can take a photo of any plant or animal, and the app provides detailed information about the species. In addition to identification, the application fosters a community of nature enthusiasts, allowing users to connect and share their experiences. By addressing the limitations of traditional field guides and online forums, Cnature offers an innovative and user-friendly tool that enhances the exploration of nature. The application is available on both iOS and Android platforms, making it accessible to a wide audience.
Empowerment Solar
Grant in 2016
Empowerment Solar fosters energy independence and economic prosperity across the Middle East by supplying affordable and easy access to reliable and clean solar electricity. They design and install distributed solar electricity systems for Palestinian businesses in the West Bank, eventually expanding across the region. They save Palestinian firms (who pay 70% more than Americans for electricity) 1,000s of dollars annually and eliminate electricity-shortage constraints plaguing West Bank companies.
Panda Chocolate
Grant in 2016
They have developed a chocolate bar the wins every blind tasting test - and this is what they offer. They have launched with a crowd funding campaign in Israel that broke records, and now officially opening their factory.
Otsimo
Grant in 2016
Otsimo, founded in 2016 and headquartered in San Francisco with an R&D office in Turkey, is dedicated to democratizing early childhood education, particularly for children with Autism Spectrum Disorder. The company develops assistive technology that offers a unique and informative experience through its award-winning application, which utilizes the Applied Behavior Analysis (ABA™) technique. This platform provides families and special education teachers with tools to support children's learning and monitor their progress. Otsimo's reach extends to over 25,000 users across 86 countries, making its resources accessible for both personal and educational use. The application is compatible with iOS and Android devices, and it also features a free open-source AAC communication tool.
Inspecto Solutions
Non Equity Assistance in 2016
Inspecto Solutions Ltd specializes in developing a portable nanoscale scanner designed to detect food contaminants quickly and cost-effectively. Founded in 2016 and headquartered in Israel, the company provides an application that serves a wide range of stakeholders in the food industry, including farmers, producers, suppliers, buyers, retailers, and quality assurers. Inspecto's technology overcomes the limitations of traditional laboratory methods, allowing users to identify contaminants in minutes rather than relying on lengthy sampling processes. The solution offers real-time analysis of various parameters and integrates cloud storage with blockchain technology to ensure data safety and enhance traceability. By enabling large volumes of scans, Inspecto Solutions aims to improve business performance through effective quality assurance and supply chain management.
PayBox
Seed Round in 2015
PayBox is a virtual bank account for groups, teams and communities who wish to collect, manage and spend money collectively. PayBox was designed for millennials and generation Y after understanding the lack of proper tools to handle the complexity and diversity of group payments. During 2015, PayBox has been elected as the MOST promising FinTech startup in ISRAEL and secured a seed investment from the Bank Poalim, the largest bank in Israel.
MedAware
Grant in 2013
MedAware provides innovative solutions that save lives, improve patient safety, and significantly reduce healthcare costs. MedAware’s patent-pending technology uses big data analytics and machine learning algorithms to analyze large scale data of electronic medical records, and learn automatically how physicians treat patients in real life scenarios. With MedAware, healthcare providers, payers, and pharmacy chains can leverage their big data to identify and eliminate a wide range of prescription errors and provide better risk management. Founded in 2012, MedAware is based in Raanana, Israel.
Pixtr
Grant in 2013
Pixtr Ltd. is a mobile photo editing application company founded in 2012 and based in Haifa, Israel. The application is designed to enhance photographs automatically, allowing users to achieve professional-quality results without requiring photography expertise. By focusing on the main subjects of images, particularly people, Pixtr improves their appearance, ensuring they look their best regardless of personal insecurities. The application features tools for eliminating skin blemishes, correcting red-eye, and enhancing selfies, making it suitable for both individual and group photos. Pixtr aims to make advanced image improvement accessible to the general public, with aspirations to become a standard in the photography space, ensuring that all online images benefit from its technology.
Vecoy
Grant in 2013
Vecoy Nanomedicines Ltd., a privately held company, incorporated in Israel in 2010, is a leading company in the application of nanomedicine technologies to the complex issues of viral diseases. The Vecoy technology will fundamentally change the treatment of viral infections by administering novel nano-scale virus-traps that capture and destroy viruses.
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