MassVentures

Bloomer Tech, founded in 2015 and based in Cambridge, Massachusetts, is focused on enhancing women's health through innovative technology embedded in everyday clothing, specifically bras. The company develops fabric engineering technology that integrates biometric sensors to monitor vital health metrics, including electrocardiograms, pulse rates, respiratory rates, and heart rhythms. By leveraging machine learning and ordinary fabrics, Bloomer Tech creates a platform for personalized detection, monitoring, and treatment of chronic diseases, particularly those related to cardiovascular health. The collected data is analyzed and made accessible to users, healthcare providers, and medical professionals, fostering real-time healthcare solutions. Through its efforts, Bloomer Tech aims to build a comprehensive dataset on women’s heart health and contribute to addressing global cardiovascular health challenges.

Ortholevo develops joint injectable therapies that helps to cure tight, restrained joints.

BioSens8 is a developer of advanced biosensors designed to enhance health monitoring and prevent chronic diseases. The company's innovative platform offers real-time, quantitative biosensors that serve various applications. In healthcare, these biosensors assist women in assessing their fertility health, providing crucial information for family planning. In agriculture, BioSens8's technology enables farmers to manage herds effectively and optimize animal reproduction. Additionally, the biosensors can evaluate environmental health, contributing to the revitalization of fragile ecosystems. By catering to the healthcare, agriculture, military, and biomanufacturing sectors, BioSens8 aims to provide efficient solutions for holistic health monitoring.

Osmoses specializes in clean membrane technology aimed at decarbonizing gas separations, with a goal of eliminating one gigaton of carbon emissions annually. The company has developed advanced molecular filters that offer exceptional size selectivity, enabling the purification of hydrogen and natural gas. Additionally, these filters facilitate large-scale carbon capture, significantly transforming traditional chemical separation processes. By reducing energy consumption and carbon emissions in industrial operations, Osmoses provides a solution that helps businesses lower costs, minimize product loss, and create value for their clients, contributing to broader efforts in combating climate change.

PhagePro is an early-stage biotechnology therapeutics company focused on developing bacteriophage-based products aimed at preventing bacterial infections, particularly in vulnerable communities worldwide. By offering innovative alternatives for disease prevention, PhagePro seeks to control outbreaks in both clinical and community settings. Its products play a crucial role in addressing public health challenges, helping to prevent fatal diseases such as cholera and enhancing overall health outcomes.

Theromics Inc. is a biotechnology company focused on developing innovative cell therapies, particularly in the field of thermal ablation for cancer treatment. Founded in 2016 and based in West Bridgewater, Massachusetts, the company has created HeatSYNC Gel, a biopolymer thermal accelerant designed to enhance the effectiveness of microwave and radiofrequency ablation procedures. This gel improves the delivery and absorption of thermal energy in soft tissue and bone, optimizing the ablation zone's shape and volume. By increasing local tissue electrical conductivity, HeatSYNC Gel helps to prevent heat loss due to blood flow, allowing for more precise targeting of tumors and protecting surrounding healthy tissue. The gel can be administered through various methods, including syringe, laparoscope, and bronchoscope, and is intended to improve the overall efficacy of thermal ablation therapies while enabling personalized treatment approaches.

Notch Inc., located in Cambridge, Massachusetts, specializes in developing advanced metamaterial solutions that enhance antenna technology. The company's innovations enable electronically controlled beamforming, which improves communication ranges and performance. Additionally, Notch Inc. incorporates features that bolster cybersecurity, ensuring that their solutions not only optimize connectivity but also protect against potential threats. Through its cutting-edge technology, Notch Inc. aims to address the evolving needs of modern communication systems.

Advanced Silicon Group is a nanotechnology company established in 2015, focused on commercializing innovative silicon nanotechnology developed by its employees. The company specializes in measuring host cell proteins in biomanufacturing, offering a range of technologies that include photovoltaics, lithium-ion batteries, microfluidics, and micro-electromechanical systems (MEMS). By leveraging silicon nanowire arrays, Advanced Silicon Group aims to enhance the performance of its clients' products while reducing costs, particularly through the development of next-generation biosensors that enable the simultaneous measurement of multiple protein concentrations.

Versatope Therapeutics is a preclinical-stage biotechnology company specializing in immunotherapy. The company has developed a unique bacterial factory nanoparticle technology that allows for the display of multiple epitopes, addressing the challenges of strain-specific immunity. This innovative approach aims to enhance vaccine potency and improve therapeutic delivery. By enabling the creation of a single vaccine capable of protecting against multiple strains of influenza, Versatope seeks to provide solutions that can significantly advance vaccine development for biotechnology companies.

Emvolon is a technology company focused on developing a platform that facilitates the distributed production of chemicals from wasted resources, particularly natural gas at flare sites. By converting this wasted gas into usable chemicals, Emvolon addresses a variety of industrial applications and offers carbon-negative fuel alternatives. The company's innovative approach reimagines conventional diesel engines as miniature chemical reactors, allowing for efficient and localized chemical production. This method eliminates the need for large refineries and chemical plants, making it economically viable for smaller production facilities. Emvolon's technology aims to provide communities with the necessary raw materials while promoting sustainability and reducing waste.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

EnVision Endoscopy specializes in developing medical devices for endoscopic surgeries, focusing on enhancing clinical outcomes for patients and efficiency for healthcare providers. The company's flagship product is an image-guided suturing system that attaches to standard flexible endoscopes, facilitating tissue approximation during surgical procedures. This biodegradable, single-use device simplifies various surgical tasks, making it more accessible for gastroenterologists and surgeons. By streamlining procedures, EnVision Endoscopy aims to reduce both procedure times and associated mortality rates, thereby improving overall patient care in the medical field.

Electrified Thermal Solutions is a company focused on decarbonizing industrial processes by replacing fossil fuels with renewable heat. Founded in 2021 and based in Medford, Massachusetts, the company originated from research conducted at MIT's Department of Nuclear Science and Engineering. Its innovative approach involves developing energy storage technology that converts intermittent renewable electricity into constant heat using low-cost conductive ceramic blocks. This technology enables various industrial sectors to utilize zero-carbon heat, contributing to a significant reduction in energy consumption's carbon footprint. Through its efforts, Electrified Thermal Solutions aims to facilitate an energy revolution that promotes sustainability in industrial applications.

Gel4Med LLC is a Boston-based medical technology company established in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix designed to eliminate antibiotic-resistant bacteria while promoting tissue regeneration. By utilizing bioinspired and engineered materials, Gel4Med aims to address significant healthcare challenges, particularly in wound care. Their leading technology employs a self-assembling peptide mechanism that acts as both an antibacterial barrier and a promoter of tissue regeneration, thus enhancing patient outcomes and preventing infections during surgical procedures.

Guardion specializes in advanced sensor technology aimed at enhancing safety and security through innovative detection systems. The company has developed the world's first radiation detector that leverages the unique quantum properties of nanomaterials, resulting in low-cost, sensitive, and energy-efficient devices suitable for widespread deployment. Guardion's products include analytical instruments and portable chemical and radiation detectors, designed for use in challenging environments across various sectors, including aerospace, medical, and national security. Recognized for its contributions to technology and innovation, Guardion received the MassChallenge 2017 Gold Prize and the Technology in Space Prize from the Center for Advancement in Science in Space and Boeing. In early 2018, the company was selected for the inaugural cohort of the Techstars Autonomous Tech Accelerator, sponsored by the Air Force.

Transcend Air is a company focused on the development and design of aircraft aimed at enhancing private air travel experiences. It specializes in vertical takeoff and landing (VTOL) aircraft, catering to commercial, private, and military sectors. In addition to manufacturing aircraft, Transcend Air operates a short-haul scheduled airline service that connects various cities, offering high-speed travel solutions for both passenger and military cargo transportation.

Eyebot is a company focused on revolutionizing eye examination technology to enhance access to vision care. They have developed a freestanding self-service vision testing terminal that allows users to receive accurate eye prescriptions directly at the point of sale. This automated experience aims to reduce barriers to obtaining eye care, making it easier and more efficient for individuals to address their vision needs. By providing ophthalmologists with a proactive tool for eye examinations, Eyebot contributes to improved quality of life for patients while also facilitating cost savings within the healthcare system.

Active Surfaces, a Massachusetts-based company, specializes in commercializing ultra-thin-film solar technology developed at MIT. Its core business involves creating flexible, lightweight solar panels that can be seamlessly integrated into everyday materials and surfaces, revolutionizing the conventional energy sector. The company's innovative manufacturing approach significantly reduces production costs, making solar power more accessible and affordable. This technology has the potential to transform semiconductor and electronics manufacturing, driving down costs for both module production and installation. By enabling virtually any surface to generate power, Active Surfaces aims to accelerate the transition to a cleaner, more sustainable future.

Adhesion Technologies is a bio-adhesive producer offers an alternative to toxic furniture glues, promoting to reduce chemical exposure.

Worcester Polytechnic Institute (WPI), located in Worcester, Massachusetts, is a prestigious technological university founded in 1865. Renowned for its commitment to project-based learning, WPI emphasizes practical application of theoretical knowledge to address real-world challenges. The university boasts a distinguished faculty and state-of-the-art research facilities, fostering an environment rich in innovation and collaboration. WPI attracts ambitious students eager to engage in hands-on experiences that prepare them to make meaningful contributions to society. With a strong focus on developing skills that are crucial in today’s dynamic landscape, WPI positions itself as a leader in education and research, dedicated to empowering its students and faculty to achieve excellence.

Dottir Labs specializes in developing spectroscopy sensor technology tailored for aqueous environments. This technology detects and measures nutrients, metabolic markers, and both organic and non-organic waste products in real-time, empowering clients to achieve sustainability through data-driven insights.

ThermoBionics specializes in the production of wearable cooling goods that leverage innovative technology to enhance cooling efficiency while reducing weight. The company's proprietary, patent-pending technology effectively manages the body's thermoregulatory functions, allowing users to minimize sweating and facilitate moisture evaporation, regardless of external temperature and humidity conditions. This advancement provides a practical solution for individuals seeking comfort in varying environmental conditions.

Benchmark Labs, based in San Francisco, California, specializes in AI-driven weather forecasting tailored for the agricultural sector and other industries. The company delivers precise, asset-specific forecasts that help clients navigate the challenges posed by changing weather patterns. By utilizing Internet of Things (IoT) sensors from various manufacturers, Benchmark Labs provides critical data that enables organizations to optimize renewable energy generation and manage water allocation effectively. The accuracy of their forecasts is essential for maintaining infrastructure and operational efficiency in the face of increasing weather variability.

MacroCycle Technologies is a company developing a chemical recycling process to convert polyethylene terephthalate (PET) and polyester-fiber waste into virgin-grade plastics. Their proprietary technology, based on synthesizing cyclic macromolecules, enables the production of recycled PET with lower energy use than traditional methods. This process offers a sustainable, zero-carbon, and cost-competitive solution for plastic upcycling, contributing to a circular economy.

Blaze Power operates as a lithium-ion battery materials manufacturer. It innovates and commercializes iron-based cathode materials to enable mass-market electrification in transportation and energy storage. The company is driven to industrialize these cathodes in purpose-built inflation reduction act-compliant facilities.

Western New England University, established in 1919, is a private, non-profit institution located in Springfield, Massachusetts. It offers a range of undergraduate and graduate programs, with notable strengths in Pharmacy and Engineering. The university is known for its small size, fostering a close-knit community where students can build relationships with professors and peers. It provides a comprehensive academic experience, with departments in Arts and Sciences, Business, and Engineering, along with a Pre-Pharmacy major leading to a graduate Pharmaceutical Sciences program. Additionally, it offers graduate degrees in Law, Engineering, and Business. The university enriches student life through various on-campus events, performing arts groups, and literary publications, as well as social activities and field trips. Admission requirements vary by program, and financial aid options are available to support tuition costs.

River Otter Renewables is a recycling comany that produced biocrude oil from plant and waste as well as sewage and plastic waste.

Feon develops new-molecule-based liquid electrolytes for lithium-ion and lithium-metal batteries.

Kanda Industries designs and manufactures the custom furnitures for homes and Offices.

Seia Bio is a biotechnology company that specializes in the development and production of non-model microbes. These are beneficial microorganisms that are not typically studied in laboratories but play crucial roles in various industries, such as agriculture. Seia Bio's core business involves enhancing the shelf-life and temperature stability of these non-model microbes through a proprietary coating technology. This process protects the microbes from harsh environmental conditions, ensuring their viability and effectiveness. By doing so, Seia Bio aims to improve the yield and sustainability of crops, ultimately benefiting farmers and the agricultural industry.

Reveal Pharmaceuticals focuses on developing innovative MRI contrast agents that provide a gadolinium-free alternative to existing gadolinium-based contrast agents (GBCAs). The company aims to enhance medical imaging safety for all patients, particularly those at risk from gadolinium exposure. Its pipeline includes precision imaging agents designed to assist in the diagnosis and treatment of conditions such as pulmonary embolism and cancer. By integrating its patented gadolinium-free RVP platform with targeted molecular probes, Reveal Pharmaceuticals enables healthcare professionals to conduct safer scans without the need for biopsies, thereby supporting the advancement of targeted therapeutics and personalized medicine.

Advanced Silicon Group is a nanotechnology company established in 2015, focused on commercializing innovative silicon nanotechnology developed by its employees. The company specializes in measuring host cell proteins in biomanufacturing, offering a range of technologies that include photovoltaics, lithium-ion batteries, microfluidics, and micro-electromechanical systems (MEMS). By leveraging silicon nanowire arrays, Advanced Silicon Group aims to enhance the performance of its clients' products while reducing costs, particularly through the development of next-generation biosensors that enable the simultaneous measurement of multiple protein concentrations.

Irradiant Technologies, founded in 2020 and based in Cambridge, Massachusetts, specializes in advanced nanofabrication utilizing implosion fabrication lithography. The company focuses on developing a platform that facilitates the ultrafast three-dimensional assembly of mixed materials, such as conductors, semiconductors, dielectrics, proteins, and DNA, with nanoscale precision and gradient control. This innovative approach enables the creation of novel photonic and optical components, providing light-based alternatives for applications in telecommunications, computation, and sensing.

Southie Autonomy is a Boston-based company founded in 2017 that specializes in developing robot software allowing industrial robots to be easily re-purposed and re-deployed by individuals without robotics expertise or technical skills. The company's automation system facilitates quick setup and execution of new robotic tasks, making it feasible for businesses to justify the use of automation in a wider range of applications, such as kitting, palletizing, and simple assembly. By lowering the time, cost, and skill barriers associated with robotic automation, Southie Autonomy aims to help businesses achieve a faster return on investment.

AI platform producing compostable and biodegradable plastic alternatives

Gel4Med LLC is a Boston-based medical technology company established in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix designed to eliminate antibiotic-resistant bacteria while promoting tissue regeneration. By utilizing bioinspired and engineered materials, Gel4Med aims to address significant healthcare challenges, particularly in wound care. Their leading technology employs a self-assembling peptide mechanism that acts as both an antibacterial barrier and a promoter of tissue regeneration, thus enhancing patient outcomes and preventing infections during surgical procedures.

Osmoses specializes in clean membrane technology aimed at decarbonizing gas separations, with a goal of eliminating one gigaton of carbon emissions annually. The company has developed advanced molecular filters that offer exceptional size selectivity, enabling the purification of hydrogen and natural gas. Additionally, these filters facilitate large-scale carbon capture, significantly transforming traditional chemical separation processes. By reducing energy consumption and carbon emissions in industrial operations, Osmoses provides a solution that helps businesses lower costs, minimize product loss, and create value for their clients, contributing to broader efforts in combating climate change.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

AmberGen, Inc. is a privately-held company based in the Boston area, established in 1995 to commercialize innovative photonic technology originally developed at Boston University. The company focuses on advancing therapeutics and diagnostics by addressing significant challenges in medicine. AmberGen employs patented techniques in proteomics and utilizes light-based control of biomolecules to create photocleavable linkers and protein engineering reagents. Its services encompass drug discovery, the development of high-throughput multiplex immuno-diagnostic assays, and mass spectrometric imaging for advanced tissue and array scanning. These innovations enable medical practitioners to detect diseases at earlier stages, thereby enhancing diagnostic capabilities and improving patient outcomes.

EnVision Endoscopy specializes in developing medical devices for endoscopic surgeries, focusing on enhancing clinical outcomes for patients and efficiency for healthcare providers. The company's flagship product is an image-guided suturing system that attaches to standard flexible endoscopes, facilitating tissue approximation during surgical procedures. This biodegradable, single-use device simplifies various surgical tasks, making it more accessible for gastroenterologists and surgeons. By streamlining procedures, EnVision Endoscopy aims to reduce both procedure times and associated mortality rates, thereby improving overall patient care in the medical field.

Northeastern University, founded in 1898, is a private, research-intensive university located in Boston, Massachusetts. It offers a wide range of undergraduate and graduate programs, including doctorate degrees, across nine colleges and schools. Additionally, it provides select advanced degrees at graduate campuses in Charlotte, North Carolina, and Seattle. The university is renowned for its experiential learning approach, integrating real-world experience into its academic curriculum.

Rendever is a company focused on addressing social isolation among seniors through virtual reality experiences. Its platform is utilized in senior living communities and healthcare settings to alleviate feelings of depression and loneliness by promoting personal connections. Participants can engage in group sessions to fulfill bucket list items, revisit significant locations, and share stories, thereby enhancing their emotional well-being. Rendever collaborates with notable senior living operators and healthcare systems, and its initiatives are supported by research from organizations such as the NIH and NIA. The company also has commercial partnerships with prominent entities, including AARP and Verizon, to expand its reach and impact.

Haystack Ag supports growers and global carbon markets with tools for high-accuracy, cost-effective soil carbon measurement.

Stitch3D is a cloud platform designed for hosting, viewing, analyzing, and sharing 3D files. The company focuses on streamlining the process of translating complex spatial data into actionable insights, significantly reducing the time required for such tasks. By utilizing artificial intelligence and machine learning algorithms, Stitch3D enables differential analysis, feature extraction, geometric search, and predictive maintenance. This technology allows enterprises to collect, aggregate, and manage 3D data in a more simplified and accessible manner.

Fourier is a thermal management solutions ranging from high power density electronics to renewable energy to space applications.

Phoenix Tailings Inc. is a Massachusetts-based company that focuses on the recycling and re-mining of mining tailings and hazardous by-products, such as Bauxite Residue, to produce essential metal products. Founded in 2019, the company aims to extract strategic materials critical to various industries, including aerospace, defense, automotive, biotechnology, and electronics. By treating mining and refining waste as new ore, Phoenix Tailings provides an innovative solution to eliminate hazardous environmental waste while creating primary metals sustainably and economically. This approach not only addresses the demand for metals in multiple sectors but also promotes environmentally friendly practices by offering carbon-free alternatives.

Notch Inc., located in Cambridge, Massachusetts, specializes in developing advanced metamaterial solutions that enhance antenna technology. The company's innovations enable electronically controlled beamforming, which improves communication ranges and performance. Additionally, Notch Inc. incorporates features that bolster cybersecurity, ensuring that their solutions not only optimize connectivity but also protect against potential threats. Through its cutting-edge technology, Notch Inc. aims to address the evolving needs of modern communication systems.

Aclarity, LLC is a cleantech startup established in 2017 and based in the United States. The company specializes in manufacturing and marketing advanced water purification devices designed for residential use. Aclarity's systems utilize innovative electrochemical technology to effectively eliminate a wide range of contaminants, including pathogens, metals, volatile organic compounds (VOCs), per- and polyfluoroalkyl substances (PFAS), and ammonia from water. These devices provide customers with cost-effective and low-maintenance solutions for comprehensive water treatment, addressing the pressing need for clean water in homes and contributing to broader environmental sustainability efforts.

Loop CO2 is a company focused on developing innovative technology that transforms carbon dioxide into essential products, contributing to a sustainable future. By converting CO2 into items such as cosmetic oils, adhesives, and thermoplastic elastomers, Loop CO2 enables its customers to minimize their environmental impact through the use of eco-friendly alternatives. The company's solutions aim to address climate challenges while promoting the utilization of carbon emissions in a productive manner.

Electrified Thermal Solutions is a company focused on decarbonizing industrial processes by replacing fossil fuels with renewable heat. Founded in 2021 and based in Medford, Massachusetts, the company originated from research conducted at MIT's Department of Nuclear Science and Engineering. Its innovative approach involves developing energy storage technology that converts intermittent renewable electricity into constant heat using low-cost conductive ceramic blocks. This technology enables various industrial sectors to utilize zero-carbon heat, contributing to a significant reduction in energy consumption's carbon footprint. Through its efforts, Electrified Thermal Solutions aims to facilitate an energy revolution that promotes sustainability in industrial applications.

PathMaker Neurosystems is a neurotechnology company focused on developing non-invasive treatments for serious neurological disorders, particularly neuromotor conditions. The company is advancing a platform that employs neuronal hyperexcitability suppression, utilizing a multi-site, precision-targeted neuromodulatory approach. Initially, PathMaker is applying this innovative technology to address issues related to stroke and amyotrophic lateral sclerosis (ALS). They are in the process of manufacturing a non-invasive device specifically designed to treat post-stroke spasticity. This novel approach enables the regulation of motor neuron excitability, allowing patients to receive effective treatment without the need for drugs or surgery.

AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.

Florrent is a bio-based materials and energy storage company focused on addressing key challenges in global decarbonization and the electrification of transportation and buildings. It specializes in the development of energy-density ultracapacitors made from sustainable hemp biomass sourced from a network of BIPOC farmers. These ultracapacitors enhance the stability of electrical grids and facilitate the integration of renewable energy sources, electric vehicles, and net-zero buildings. By enabling communities to locally generate, store, and utilize renewable power, Florrent contributes to the transition towards a resilient, renewable, and equitable energy economy.

The University of Massachusetts Amherst is a public research and land-grant university that offers undergraduate, master's, and doctoral programs. It serves as the flagship campus of the University of Massachusetts system. The university has multiple academic departments and research facilities that support a range of disciplines.

Carbix is a company focused on converting atmospheric carbon dioxide into carbonates, which serve as raw materials for various industrial products. Utilizing innovative bioreactor technology, Carbix captures CO2 from industrial flue gas and rapidly transforms it, along with mineral inputs, into usable raw materials within hours. The company employs advanced weathering techniques powered by renewable energy or energy-from-waste, enhancing the sequestration of CO2 emissions. This process not only helps mitigate climate change by reducing atmospheric carbon but also enables businesses to source industrial materials sustainably.

Arrakis Materials converts CO₂ into carbon-negative minerals, enabling carbon storage and utilization.

Lithios is a technology company specializing in advanced lithium extraction through innovative electrochemical methods. The firm focuses on capturing and releasing lithium from complex mixtures, which are traditionally challenging to process. By leveraging breakthroughs in applied electrochemistry, Lithios offers solutions that facilitate low-cost and selective extraction of lithium from previously untapped brine resources. This approach not only enhances the efficiency of lithium recovery but also aligns with sustainable practices, supporting the growing demand for lithium in various industries, particularly in the context of an electric future.

Aloft Systems specializes in maritime transportation by developing innovative wind propulsion technology aimed at enhancing the efficiency of existing vessels. The company focuses on creating self-contained wind propulsion units that can be integrated into ships, allowing for autonomous operation. This technology significantly reduces emissions and eliminates fuel costs, making it accessible for a wide range of vessels. By enabling shipping companies to utilize direct wind propulsion, Aloft Systems enhances cargo transportation on point-to-point routes, thereby improving delivery reliability and contributing to a more sustainable maritime industry.

Prisere LLC is a resilience consulting firm that specializes in helping businesses worldwide navigate and mitigate risks, particularly those related to climate change and disasters. The company offers a range of services, including risk communications, mapping, and software applications, along with training and technical advisory services. By leveraging partnerships with various institutions, Prisere aims to enhance clients' resilience, improve risk management, and facilitate access to affordable insurance, ultimately bolstering their long-term profitability and stability.

Stepwise specializes in home electrification services, focusing on the installation of electric vehicle (EV) chargers and heat pumps. The company has developed a software-defined smart device that connects to an electric panel, acting as an intermediary between the panel and the EV charger. This device monitors energy consumption and manages the charger, ensuring efficient and reliable charging services for clients. By leveraging this technology, Stepwise aims to enhance the accessibility and effectiveness of home electrification solutions.

AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.

EnVision Endoscopy specializes in developing medical devices for endoscopic surgeries, focusing on enhancing clinical outcomes for patients and efficiency for healthcare providers. The company's flagship product is an image-guided suturing system that attaches to standard flexible endoscopes, facilitating tissue approximation during surgical procedures. This biodegradable, single-use device simplifies various surgical tasks, making it more accessible for gastroenterologists and surgeons. By streamlining procedures, EnVision Endoscopy aims to reduce both procedure times and associated mortality rates, thereby improving overall patient care in the medical field.

The principal mission of the Company is to provide technology and technology services to industry and public sector agencies for enhanced productivity, improved safety, and reduced costs.

Pison Technology, Inc., established in 2016 and headquartered in Boston, Massachusetts, specializes in developing and marketing wearable devices. These devices are designed to capture and filter signals sent to the nervous system, primarily serving individuals with amyotrophic lateral sclerosis (ALS). Pison's innovative, non-invasive electroneurography (ENG) algorithms and sensor array technology aim to optimize cognitive and physiological capabilities through gesture control, with applications in cognitive enhancement, disease diagnosis, and improving overall quality of life.

AmberGen, Inc. is a privately-held company based in the Boston area, established in 1995 to commercialize innovative photonic technology originally developed at Boston University. The company focuses on advancing therapeutics and diagnostics by addressing significant challenges in medicine. AmberGen employs patented techniques in proteomics and utilizes light-based control of biomolecules to create photocleavable linkers and protein engineering reagents. Its services encompass drug discovery, the development of high-throughput multiplex immuno-diagnostic assays, and mass spectrometric imaging for advanced tissue and array scanning. These innovations enable medical practitioners to detect diseases at earlier stages, thereby enhancing diagnostic capabilities and improving patient outcomes.

Kinto.Care is an online platform designed to enhance communication and support for caregivers, particularly those caring for loved ones with dementia. The platform offers user-generated content and digital tools that facilitate care team collaboration, medication management, and tracking of health data. By providing practical advice, care planning, and group learning opportunities, Kinto.Care aims to empower family members to effectively coordinate care and manage their loved ones' medical needs through a unified interface.

Mesodyne is an engineering and manufacturing company focused on innovative electricity generation solutions, particularly through its patented LightCell technology, which converts various fuels into electricity using light. Founded in 2018 by Drs. Veronika Stelmakh and Walker Chan, the company aims to deliver portable and reliable power generation systems to military and commercial users. Mesodyne's compact power generators enhance the endurance of small autonomous systems, offering efficient and long-lasting energy sources that bridge the gap between traditional batteries and internal combustion engines. This technology is designed to alleviate the burden on dismounted warfighters and emergency responders while extending the operational range of unmanned vehicles, wearables, and other equipment.

Leuko Labs, Inc., established in 2017 and headquartered in Boston, Massachusetts, specializes in developing healthcare equipment for non-invasive monitoring of white blood cells. Their flagship product, PointCheck, enables frequent testing of immunosuppressed patients, such as those undergoing chemotherapy, without the need for blood draws or laboratory infrastructure. This innovation aims to enhance patients' quality of life and improve clinical outcomes by facilitating early detection of life-threatening infections and personalized chemotherapy management.

Radical Plastics, Inc., based in Winchester, Massachusetts, develops biodegradable plastic compounds designed to address plastic pollution. Incorporated in 2018, the company utilizes a proprietary, naturally occurring catalyst to blend with conventional plastics, making them fully biodegradable in the natural environment. Their innovative technology offers soil degradable compounds specifically for agricultural film, providing an economically viable solution for brands seeking drop-in replacements for traditional plastics. Through its commitment to sustainability, Radical Plastics aims to contribute to reducing plastic waste and promoting environmental health.

Reveal Pharmaceuticals focuses on developing innovative MRI contrast agents that provide a gadolinium-free alternative to existing gadolinium-based contrast agents (GBCAs). The company aims to enhance medical imaging safety for all patients, particularly those at risk from gadolinium exposure. Its pipeline includes precision imaging agents designed to assist in the diagnosis and treatment of conditions such as pulmonary embolism and cancer. By integrating its patented gadolinium-free RVP platform with targeted molecular probes, Reveal Pharmaceuticals enables healthcare professionals to conduct safer scans without the need for biopsies, thereby supporting the advancement of targeted therapeutics and personalized medicine.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

Extend Biosciences Inc. is an emerging biotechnology company developing a novel drug delivery platform technology that improves the pharmacokinetic properties of peptides and proteins. Peptides have been particularly challenging to bring to market because they are removed from circulation prior to administering therapeutic value. Their proprietary platform technology significantly improves the circulating half-life and bioavailability of peptides and proteins, enabling the scientific community to truly develop potent and specific drugs. Their mission is to revolutionize drug delivery and give patients a better quality of life.

Jaxon.AI is an artificial intelligence platform designed to assist data science teams throughout the research, design, and build process. By leveraging technologies such as ChatGPT, Jaxon addresses complex, use case-specific challenges and creates detailed blueprints that guide users in adhering to optimal development paths. Its proprietary reasoning engine simulates model performance to evaluate trade-offs, allowing teams to identify the most effective solutions for their projects. This structured approach enhances the likelihood of success in AI initiatives, streamlining the design cycle and ensuring that users can navigate the complexities of AI development effectively.

Gradient is a developer of secure software that addresses fundamental issues of trust and authenticity in the digital landscape. The company's solutions focus on redefining identity and data authentication, providing a framework for establishing trust and facilitating the sharing of provable statements while ensuring privacy and security. This enables users to collaborate openly without sacrificing digital security or integrity. Gradient's infrastructure is designed to foster decentralized trust, contributing to safer and more reliable digital interactions.

Eden is focused on developing a sustainable platform for natural resource recovery, aiming to create a carbon-neutral future. The company has introduced a novel method known as Pulsed Electrical Well Stimulation (PEWS), which is a patent-pending technology designed to replace traditional hydraulic fracturing. This innovative approach eliminates the need for water injection and addresses the logistical challenges and environmental risks associated with conventional fracking methods. By utilizing high-voltage electricity and proprietary modeling techniques, Eden enhances rock permeability with precision, facilitating effective resource extraction across various geological settings. This technology not only reduces costs but also minimizes the negative impacts typically associated with hydraulic fracturing, positioning Eden as a leader in environmentally responsible resource recovery.

Aclarity, LLC is a cleantech startup established in 2017 and based in the United States. The company specializes in manufacturing and marketing advanced water purification devices designed for residential use. Aclarity's systems utilize innovative electrochemical technology to effectively eliminate a wide range of contaminants, including pathogens, metals, volatile organic compounds (VOCs), per- and polyfluoroalkyl substances (PFAS), and ammonia from water. These devices provide customers with cost-effective and low-maintenance solutions for comprehensive water treatment, addressing the pressing need for clean water in homes and contributing to broader environmental sustainability efforts.

PathMaker Neurosystems is a neurotechnology company focused on developing non-invasive treatments for serious neurological disorders, particularly neuromotor conditions. The company is advancing a platform that employs neuronal hyperexcitability suppression, utilizing a multi-site, precision-targeted neuromodulatory approach. Initially, PathMaker is applying this innovative technology to address issues related to stroke and amyotrophic lateral sclerosis (ALS). They are in the process of manufacturing a non-invasive device specifically designed to treat post-stroke spasticity. This novel approach enables the regulation of motor neuron excitability, allowing patients to receive effective treatment without the need for drugs or surgery.

Prezerv Technologies is a provider of GPR technologies and services, offering scalable solutions for businesses of all sizes.

Harmony Desalting is a trailblazing company specializing in water treatment, with a focus on providing clean water access through its innovative Reverse Osmosis (RO) batch process. The company operates by offering advanced desalination technology, combining new processes, membranes, and insights to help clients reduce the cost of seawater RO by enhancing plant productivity and minimizing seawater intake size.

SilarTek, founded in 2020 and based in Leominster, Massachusetts, focuses on developing innovative solar silicon technology to enhance the affordability of solar panels. The company employs molten salt electrolysis combined with advanced molten salt compositions to produce low-cost solar-grade silicon. This technology aims to make solar energy more accessible to a broader consumer base, facilitating the adoption of renewable energy solutions.

Worcester Polytechnic Institute (WPI), located in Worcester, Massachusetts, is a prestigious technological university founded in 1865. Renowned for its commitment to project-based learning, WPI emphasizes practical application of theoretical knowledge to address real-world challenges. The university boasts a distinguished faculty and state-of-the-art research facilities, fostering an environment rich in innovation and collaboration. WPI attracts ambitious students eager to engage in hands-on experiences that prepare them to make meaningful contributions to society. With a strong focus on developing skills that are crucial in today’s dynamic landscape, WPI positions itself as a leader in education and research, dedicated to empowering its students and faculty to achieve excellence.

Zero Homes operates a home electrification marketplace that simplifies the process for homeowners seeking to transition to all-electric living. The platform offers a user-friendly environment where homeowners can plan, purchase, and schedule electrification projects without the need for in-home visits. Through virtual home energy assessments, Zero provides tailored decarbonization roadmaps and scoped, priced projects, allowing homeowners to receive customized guidance and assistance. This approach not only enhances home comfort but also aims to eliminate emissions, making retrofitting more accessible and efficient for homeowners.

Western New England University, established in 1919, is a private, non-profit institution located in Springfield, Massachusetts. It offers a range of undergraduate and graduate programs, with notable strengths in Pharmacy and Engineering. The university is known for its small size, fostering a close-knit community where students can build relationships with professors and peers. It provides a comprehensive academic experience, with departments in Arts and Sciences, Business, and Engineering, along with a Pre-Pharmacy major leading to a graduate Pharmaceutical Sciences program. Additionally, it offers graduate degrees in Law, Engineering, and Business. The university enriches student life through various on-campus events, performing arts groups, and literary publications, as well as social activities and field trips. Admission requirements vary by program, and financial aid options are available to support tuition costs.

The University of Massachusetts (UMass) Dartmouth is known for its rigorous academic programs, especially in the areas of engineering, law, marine science, and Portuguese studies.

Volta Energy developing technology to decarbonize energy generation.

SpadXTech specializes in developing microbe-based materials aimed at preserving natural resources and mitigating environmental issues. The company utilizes green fermentation techniques and proprietary biotechnology to create customizable cellulose-based materials derived from fast-growing microbes. These materials are designed to be strong, flexible, and durable, making them suitable for a wide range of applications. By focusing on innovative solutions, SpadXTech addresses critical challenges such as climate change, air and water pollution, and plastic waste, contributing to a more sustainable future.

M2 Thermal Solutions specializes in innovative air conditioning technology designed to enhance energy efficiency in residential environments. The company has developed a unique thermodynamic mechanism that independently regulates both dry-bulb temperature and humidity. This advanced system operates in two distinct stages, allowing for precise control based on varying indoor and outdoor conditions, without relying on traditional vapor-compression methods. By improving the cooling and dehumidification processes, M2 Thermal Solutions significantly reduces energy consumption and mitigates the impact on climate change.

GenH is a Boston-based company established in 2017 that specializes in advanced hydroelectric technology. The firm focuses on developing resilient hydropower systems that can be deployed in urban environments. By offering a modular hydropower solution, GenH aims to optimize and streamline energy generation processes at non-powered dams and canal heads. This innovative approach allows for the electrification of these sites without the need for significant construction or investment in fixed infrastructure. As a result, clients can achieve economic parity with traditional fossil fuel systems, facilitating a transition towards more sustainable energy sources.

UMass Lowell is a research university that offers bachelor, master, and doctoral degree programs.

Allium Engineering is a civil engineering company specializing in the development and manufacturing of corrosion-resistant steel rebar. The company focuses on creating innovative coating methods for steel reinforcement, addressing the significant issue of concrete infrastructure degradation. By producing rebar that does not rust, Allium Engineering enables clients to construct durable infrastructure while contributing to the reduction of carbon emissions.

Tufts University is a moderately sized institution that integrates the characteristics of a research university with those of a liberal arts college, fostering an environment of curiosity and creativity. Established with a commitment to student-centered education, Tufts emphasizes the creation and application of knowledge across a diverse range of disciplines. The university offers various programs, including degrees in public health and health informatics through its School of Medicine, and is home to the Tufts Center for the Study of Drug Development, an independent nonprofit organization that enhances the quality and efficiency of pharmaceutical development. Tufts aims to provide transformational experiences for students and faculty in an inclusive and collaborative setting, encouraging innovative thinking and active engagement in addressing complex global challenges.

Bootbox Labs is a manufacturing company that provides refrigerant-free and climate-neutral heat pumps for the HVAC industry.

Curbhub is a transportation technology company focused on enhancing freight and logistics services through innovative solutions. It utilizes a decentralized courier model to replace traditional centralized carriers, transforming linear logistics into a more efficient parallel system. Curbhub offers web-based collaborative transportation management that incorporates autonomous delivery vehicles, allowing clients to achieve cost-effective, environmentally friendly, and secure last-mile delivery options. This approach aims to streamline logistics operations and improve service efficiency for businesses in need of reliable transportation solutions.

SeaDeep is a developer of an environmental sensing platform that utilizes artificial intelligence and machine learning to enhance imaging, hyper-spectral analysis, and 3D visualization of underwater environments. The company aims to provide real-time, autonomous assessments of these environments and their substructures with unprecedented fidelity. By offering advanced data analysis techniques, SeaDeep enables clients to monitor underwater assets effectively and sustainably, facilitating efficient ocean research and development. The platform is designed to support sustainable subsea operations by delivering critical data necessary for evaluating and managing the world’s underwater resources.

PowerHouse is a company dedicated to combating climate change by providing innovative solar energy solutions. It specializes in developing a solar energy system that overcomes the limitations of traditional deployment methods, offering versatile and aesthetically pleasing options for residential, commercial, and off-grid applications. The company's platform aims to expand the reach of renewable energy, making it more accessible and desirable for clients.

Reveal Pharmaceuticals focuses on developing innovative MRI contrast agents that provide a gadolinium-free alternative to existing gadolinium-based contrast agents (GBCAs). The company aims to enhance medical imaging safety for all patients, particularly those at risk from gadolinium exposure. Its pipeline includes precision imaging agents designed to assist in the diagnosis and treatment of conditions such as pulmonary embolism and cancer. By integrating its patented gadolinium-free RVP platform with targeted molecular probes, Reveal Pharmaceuticals enables healthcare professionals to conduct safer scans without the need for biopsies, thereby supporting the advancement of targeted therapeutics and personalized medicine.

NanoView Biosciences is a biotechnology company that specializes in the development of technologies for the characterization of extracellular vesicles, particularly exosomes. Founded in 2015 and based in Boston, Massachusetts, the company utilizes its proprietary ExoView technology to provide high-throughput and cost-effective analysis solutions for life science researchers. NanoView's products, which include the ExoView R100 and ExoView tetraspanin, enable precise detection and multiparametric characterization of exosomes from complex biological samples such as blood, serum, plasma, and urine. In addition to its core products, the company offers custom assays, sample services, and a support platform to aid researchers in understanding the biological roles of exosomes and utilizing them as biomarkers for disease diagnosis, treatment, and monitoring.

DynamiCare Health, Inc. is a Boston-based company that offers a digital platform aimed at helping individuals reduce their use of drugs, alcohol, and tobacco. Founded in 2016, the platform integrates a smartphone application with substance testing hardware and a telehealth support system. It employs automated Contingency Management, an evidence-based approach shown to be effective in numerous clinical trials, to motivate users through positive reinforcement. Members can earn monetary rewards for maintaining sobriety, attending treatment, and completing self-guided therapy modules. The platform also features a DynamicCare Analytics portal, allowing healthcare providers to monitor participants' progress and receive real-time alerts regarding their risk levels. By combining technology with personalized support, DynamiCare Health seeks to guide individuals toward achieving healthier lifestyles.

Leuko Labs, Inc., established in 2017 and headquartered in Boston, Massachusetts, specializes in developing healthcare equipment for non-invasive monitoring of white blood cells. Their flagship product, PointCheck, enables frequent testing of immunosuppressed patients, such as those undergoing chemotherapy, without the need for blood draws or laboratory infrastructure. This innovation aims to enhance patients' quality of life and improve clinical outcomes by facilitating early detection of life-threatening infections and personalized chemotherapy management.

Transaera specializes in the development of energy-efficient cooling systems aimed at minimizing energy consumption and greenhouse gas emissions. The company employs an innovative desiccant material that effectively removes moisture from the air prior to the cooling process, enhancing indoor comfort. Its solutions are designed for both residential and commercial applications, providing affordable and environmentally friendly cooling options that improve indoor climate control. By reducing the energy demands typically associated with conventional air conditioning units, Transaera's technologies support greater productivity while also alleviating strain on local grid infrastructure and contributing to a more sustainable global climate.