Main Sequence Ventures

Main Sequence Ventures is a venture capital firm that focuses on investing in founders who are developing innovative industries through deep technology and frontier technologies. The firm is supported by prominent entities such as the Australian National Science Agency, CSIRO, and the Australian Federal Government, along with various private investors. Main Sequence Ventures uniquely positions itself by leveraging cutting-edge research from leading Australian public research organizations, including CSIRO and the country's numerous universities and industry research agencies, to identify and nurture high-potential startups.

Bill Bartee

Partner

Phil Morle

Partner

Mike Nicholls

Partner

Martin Duursma

Partner

Past deals in Defence

QuintessenceLabs

Venture Round in 2025
QuintessenceLabs specializes in data security technology and solutions designed to protect valuable digital information throughout its lifecycle—whether in transit, at rest, or in use. The company utilizes principles of quantum science to enhance its cybersecurity applications, focusing on robust cryptographic strategies that centralize data security management and policy control. QuintessenceLabs aims to maximize security while improving returns on investment for its clients and minimizing the complexities associated with data protection. Its diverse customer base includes notable financial institutions, technology providers, federal agencies, and defense contractors, underscoring its broad applicability across various sectors.

Arkeus

Venture Round in 2025
Arkeus specializes in the quick design, creation, and production of autonomous optical capabilities for Search, Intelligence, Surveillance, and Reconnaissance (SISR).

Quasar Satellite Technologies

Seed Round in 2023
Quasar Satellite Technologies is a sovereign company that specializes in delivering space data as a service. The company provides a multi-beam phased array ground station solution designed for satellite owners and operators in both the commercial and defense sectors. Their fully software-defined antenna system offers low latency and high throughput, ensuring secure satellite data transmission. Quasar's technology features instantaneous full-sky visibility, which allows for deep characterization of objects. This capability enables satellite operators to access cost-effective ground station services while enhancing space communications and domain awareness. Through its offerings, Quasar aims to support the LEO, MEO, and GEO satellite markets with scalable and interoperable services.

QuintessenceLabs

Series B in 2021
QuintessenceLabs specializes in data security technology and solutions designed to protect valuable digital information throughout its lifecycle—whether in transit, at rest, or in use. The company utilizes principles of quantum science to enhance its cybersecurity applications, focusing on robust cryptographic strategies that centralize data security management and policy control. QuintessenceLabs aims to maximize security while improving returns on investment for its clients and minimizing the complexities associated with data protection. Its diverse customer base includes notable financial institutions, technology providers, federal agencies, and defense contractors, underscoring its broad applicability across various sectors.

Advanced Navigation

Series A in 2019
Advanced Navigation is an Australian company that focuses on the development of advanced navigation technologies and robotics. It specializes in creating high-quality hardware and software products, drawing on expertise in areas such as sensors, global navigation satellite systems (GNSS), inertial navigation, and robotics. The company's origins in mission-critical robotics for military applications inform its product design and engineering. Advanced Navigation's devices incorporate global positioning systems (GPS) and attitude and heading reference systems (AHRS) to deliver precise position, acceleration, and orientation data, even in challenging environments. This technological capability supports clients in manufacturing and warehousing by enhancing process optimization and productivity.
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