IP Group

Enterprise Therapeutics Ltd. is a drug discovery company based in Brighton, United Kingdom, founded in 2014. It focuses on the research and development of innovative therapies for respiratory diseases, specifically targeting chronic obstructive pulmonary disease (COPD), cystic fibrosis, and asthma. The company aims to create disease-modifying therapies that address the underlying mechanisms of mucus congestion in the lungs, which can lead to breathing difficulties and increased susceptibility to lung infections. By developing these novel treatments, Enterprise Therapeutics seeks to enhance the quality of life for patients suffering from these chronic respiratory conditions.

AccelerComm Ltd specializes in providing Forward Error Correction (FEC) solutions for various communication markets, including mobile handsets, base stations, and satellite standards. Founded in 2016 and based in Southampton, United Kingdom, the company focuses on enhancing the performance of next-generation wireless communications, addressing challenges such as noise, interference, and weak signal strength. Its product offerings include a range of encoding and decoding technologies, such as Polar, Turbo, and LDPC (Low-Density Parity-Check) decoders, specifically designed to meet 3GPP compliance. By delivering innovative semiconductor IP-core products, AccelerComm aims to facilitate optimal performance in digital communications while supporting the evolving needs of the industry.

Deep Render Ltd. is a spin-out from the Department of Computing at Imperial College London. We are a London based AI start-up that is developing the next generation of media compression algorithms. Our proprietary and patented technology is at the forefront of machine learning research. Furthermore, our Biological Image Compression results are state-of-the-art, providing at least a 50% efficiency gain over the previous standards

AudioScenic Limited, founded in 2017 and headquartered in Southampton, United Kingdom, specializes in developing advanced 3D audio technology that enhances the listening experience across various sectors, including cinema, gaming, production, automotive, and public spaces. The company's innovative approach utilizes small arrays of speakers combined with head-tracking technology to deliver controlled sound beams directly to the listener's ears, creating a virtual headphone effect without the need for traditional headphones or bulky speaker setups. This technology allows users to experience immersive audio that accurately simulates sound positioned in three-dimensional space, surpassing the quality of conventional loudspeaker systems. AudioScenic's solutions are adaptable for diverse applications and are supported by their proprietary Virtua 3D Engine, which is designed for efficient signal processing across various platforms. The company collaborates closely with partners and customers to provide tailored acoustic designs, ensuring an authentic and natural audio experience for all users.

Diffblue Limited, based in Oxford, United Kingdom, specializes in artificial intelligence software that automates various coding tasks, primarily focusing on enhancing Java development through automated testing solutions. Founded in 2016 as a spin-out from the AI research group at Oxford, Diffblue's technology autonomously generates unit tests, which helps developers save time and ensure software robustness. The software not only creates fully formed tests guaranteed to compile and run, but also identifies and fixes bugs, refactors code, and maintains regression tests. By providing insights into test coverage, code testability, and complexity, Diffblue aims to transform the software development process, making it more efficient and less error-prone.

Kale United AB, founded in 2018 and headquartered in Stockholm, Sweden, specializes in providing advisory services to plant-based member companies. These services encompass marketing, public relations, sales and distribution, financing, community engagement, accounting, and human resources. The company focuses on supporting vegan startups and aims to foster growth within the plant-based food sector across the Nordic region.

Nexeon Limited is a developer and manufacturer of advanced silicon-based anode materials for rechargeable lithium-ion batteries. Founded in 2006 and headquartered in Abingdon, United Kingdom, with an additional office in Yokohama, Japan, the company focuses on creating innovative battery materials that enhance energy density and capacity. These improvements allow for the production of lighter, more powerful batteries that can support a variety of applications, including consumer electronics, electric vehicles, sustainable energy, aerospace, medical, and defense industries. By enabling longer battery life and faster charging times, Nexeon's technology plays a crucial role in advancing sustainable energy solutions and supporting the transition to a net-zero environment. The company boasts a skilled technical team with diverse expertise to drive its research and development efforts.

Oxford Science Enterprises is a venture firm based in Oxford, United Kingdom, established in 2015 in partnership with the University of Oxford. The firm focuses on building and investing in companies that develop fundamental technologies aimed at addressing significant global challenges. Its investment areas include life sciences, healthcare, artificial intelligence, software, and deep tech, targeting issues such as nuclear fusion, quantum computing, and the development of treatments for infectious diseases. By leveraging its extensive experience and a robust network of investors, entrepreneurs, and sector experts, Oxford Science Enterprises aims to foster a world-class technology ecosystem and support the growth of innovative science-based businesses.

Abliva AB is a Swedish pharmaceutical company dedicated to the research and development of treatments for primary mitochondrial diseases, which are rare and severe disorders caused by dysfunctional mitochondria responsible for cellular energy production. The company's development pipeline includes KL1333, currently in phase I clinical trials, which acts as a regulator of NAD+ and NADH, and has received orphan drug designation in both Europe and the United States. Additionally, Abliva is preparing to initiate clinical trials for NV354, an energy replacement therapy that has recently completed preclinical development. The company also focuses on NeuroSTAT, aimed at treating traumatic brain injuries. Collaborations with various institutions and organizations, including Isomerase and the University of Pennsylvania, enhance its research capabilities. Founded in 2000 and headquartered in Lund, Sweden, Abliva was previously known as NeuroVive Pharmaceutical AB until its name change in May 2020.

MoA Technology Ltd. is a plant genetics company based in Leeds, United Kingdom, that was incorporated in 2017. It was spun out from the University of Oxford and focuses on developing innovative agricultural technologies aimed at enabling farmers to produce healthy food through sustainable crop systems. The company leverages research led by Professor Liam Dolan to discover new methods that enhance agricultural productivity while promoting sustainability.

SLAMcore Limited specializes in developing simultaneous localization and mapping (SLAM) solutions tailored for various applications, including robotics, augmented reality, and autonomous vehicles. Founded in 2016 and based in London, the company has created advanced SLAM software that enables robots and devices equipped with outward-facing sensors to understand and navigate unfamiliar environments. Their technology includes Visual SLAM, sensor fusion, and Event Camera SLAM, which collectively enhance real-time spatial understanding. By fusing data from multiple sensors, SLAMcore's platform utilizes computer vision and machine learning to improve the efficiency and accuracy of robotic systems. The company offers a software development kit (SDK) that facilitates rapid prototyping for commercial products, allowing for customization on standard computing platforms. Through partnerships with original equipment manufacturers, SLAMcore aims to integrate its core technology into everyday products, making spatial intelligence more accessible and practical in various industries.

GripAble Ltd. designs and develops digital therapy devices aimed at improving rehabilitation for individuals with movement impairments such as stroke, arthritis, cerebral palsy, and trauma. Founded in 2017 and based in London, the company offers a portable, wireless handgrip device that connects to a mobile application. This application allows users to engage with therapy games while providing assessment and training for hand and arm functions. GripAble's innovative approach focuses on making therapy more accessible and engaging for patients, enabling them to practice essential daily tasks in a fun and motivating way. By combining hardware and software, GripAble addresses the needs of over 500 million people worldwide who face challenges with arm mobility, facilitating self-training both in clinical settings and at home.

Bramble Energy Ltd. is a London-based company that specializes in the design, development, and manufacture of printed circuit board (PCB) fuel cells, specifically proton exchange membrane fuel cells (PEMFCs). Incorporated in 2015, it leverages the capabilities of the global PCB industry to produce high-performance, cost-effective fuel cell stacks. The company's product lineup includes modular PCBFC stacks, ranging from 20 W to 5 kW, as well as custom-designed solutions. Bramble Energy serves various sectors, including stationary, portable, and automotive applications, aiming to provide gigawatts of fuel cell hardware. By utilizing innovative manufacturing methods and materials, the company enables clients to reduce energy consumption and lower their carbon footprints.

First Light Fusion Limited, founded in 2011 and based in Begbroke, United Kingdom, specializes in advanced implosion processes for electricity generation through inertial confinement fusion. The company originated as a spin-out from the University of Oxford and actively engages in researching and developing sustainable renewable energy solutions. It employs a team of engineers and physicists and collaborates with several academic institutions, including the University of Oxford, Warwick University, UCL, and Imperial College London. First Light Fusion focuses on harnessing fundamental physics to discover new energy sources, utilizing detailed numerical simulations and experimental validation in its research efforts.

Diffblue Limited, based in Oxford, United Kingdom, specializes in artificial intelligence software that automates various coding tasks, primarily focusing on enhancing Java development through automated testing solutions. Founded in 2016 as a spin-out from the AI research group at Oxford, Diffblue's technology autonomously generates unit tests, which helps developers save time and ensure software robustness. The software not only creates fully formed tests guaranteed to compile and run, but also identifies and fixes bugs, refactors code, and maintains regression tests. By providing insights into test coverage, code testability, and complexity, Diffblue aims to transform the software development process, making it more efficient and less error-prone.

Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Ieso Digital Health Ltd. is a provider of online, evidence-based mental health therapy, focusing on cognitive behavioral therapy (CBT) delivered through a digital platform. The company offers one-to-one therapy sessions for various mental health issues, including anxiety, depression, and phobias, as well as support for chronic physical health problems and cognitive impairments. Ieso's innovative approach combines proprietary technology with natural language processing and artificial intelligence to enhance therapy delivery through real-time monitoring and assessment. This enables therapists to provide effective care in a virtual environment, allowing patients to access support at their convenience. Serving a diverse clientele that includes health providers, private individuals, and businesses, Ieso aims to transform mental healthcare by making it more accessible and scalable. Founded in 2000 and based in Swavesey, United Kingdom, Ieso was previously known as PsychologyOnline.co.uk Limited before rebranding in 2015.

Ieso Digital Health Ltd. is a provider of online, evidence-based mental health therapy, focusing on cognitive behavioral therapy (CBT) delivered through a digital platform. The company offers one-to-one therapy sessions for various mental health issues, including anxiety, depression, and phobias, as well as support for chronic physical health problems and cognitive impairments. Ieso's innovative approach combines proprietary technology with natural language processing and artificial intelligence to enhance therapy delivery through real-time monitoring and assessment. This enables therapists to provide effective care in a virtual environment, allowing patients to access support at their convenience. Serving a diverse clientele that includes health providers, private individuals, and businesses, Ieso aims to transform mental healthcare by making it more accessible and scalable. Founded in 2000 and based in Swavesey, United Kingdom, Ieso was previously known as PsychologyOnline.co.uk Limited before rebranding in 2015.

Ultraleap Limited specializes in haptic control systems and 3D hand tracking technology, focusing on creating immersive user experiences. The company is recognized for its innovative haptic technology that utilizes ultrasound to generate tactile sensations in mid-air, allowing users to feel three-dimensional shapes and textures without physical contact. Its key products include the Leap Motion Controller, which tracks hand movements; the VR Developer Mount, designed for virtual reality applications; and the Gemini hand tracking platform. Ultraleap's solutions cater to a variety of industries, including extended reality, automotive, digital signage, industrial automation, consumer electronics, and location-based entertainment. Established in 2013 and headquartered in Bristol, United Kingdom, Ultraleap also has a subsidiary in Silicon Valley, United States. The company was previously known as Ultrahaptics until its rebranding in September 2019.

Monolith AI Limited is a London-based software company that assists engineers in enhancing the product development process through the application of machine learning and data science. Founded in 2016, Monolith AI specializes in algorithms that integrate engineering simulations with machine learning techniques to identify optimal solutions for engineering designs. The company enables organizations to leverage existing simulation and test data, allowing them to predict the behavior of new products. This approach helps businesses streamline their research and development processes by minimizing the need for extensive simulations, tests, and prototypes, ultimately leading to faster and more effective product development. Monolith AI was formerly known as UQuant Limited and rebranded in June 2018.

Alesi Surgical Ltd. specializes in the development and commercialization of laparoscopic surgical smoke handling systems aimed at enhancing the safety and outcomes of surgical procedures. Founded in 2009 and based in Cardiff, United Kingdom, the company emerged as a spin-out from the Welsh Institute for Minimal Access Therapy, benefiting from direct access to experienced surgeons and surgical trainers. Alesi Surgical's innovative products are designed to be portable and applicable in both laparoscopic and robot-assisted surgeries. Utilizing electrostatic precipitation technology, these tools effectively eliminate surgical smoke, ensuring a clear visual field during procedures. Alesi Surgical distributes its products to hospitals across Europe, the Middle East, New Zealand, and Australia.

Oxford Nanopore Technologies is a biotechnology company specializing in nanopore-based sequencing technology for analyzing DNA, RNA, proteins, and small molecules. Its diverse product line includes the portable MinION device, the benchtop PromethION, the GridION system, and Flongle, which caters to on-demand sequencing needs. The technology enables real-time data streaming and is applicable across various fields such as human genomics, cancer research, microbiology, plant science, and environmental studies. Additionally, Oxford Nanopore's products support rapid and accessible molecular analysis, making them suitable for both laboratory and field use. The company's innovations are backed by a robust patent portfolio and are utilized in over 80 countries, addressing needs in healthcare, agriculture, and education. Founded in 2005 and headquartered in Oxford, United Kingdom, Oxford Nanopore also maintains offices in several other countries, enhancing its global reach in advancing genomic research and applications.

Oxular Limited is a clinical-stage company based in Oxford, United Kingdom, focused on developing innovative retinal treatments to address various retinal diseases. Founded in 2014, the company specializes in tissue-specific drug delivery technology aimed at improving the effectiveness of treatments for conditions such as age-related macular degeneration, diabetic macular edema, retinal vein occlusion, and cystoid macular edema. By targeting specific areas within the eye, Oxular seeks to enhance therapeutic outcomes while minimizing side effects and reducing the frequency of treatments, thereby offering patients effective and life-changing solutions for their unmet medical needs.

C-Capture Limited, founded in 2008 and based in Leeds, United Kingdom, specializes in the development and design of solvent systems for the removal of carbon dioxide (CO2) from gas streams. The company utilizes its expertise in CO2-based chemistry and engineering to create absorbents for reversible CO2 capture, particularly in post-combustion processes. C-Capture focuses on providing non-toxic and economically viable carbon capture solutions for emission sources, including flue gases from power generators and hard-to-abate industries. By offering innovative technology for capturing CO2, C-Capture aims to contribute to more sustainable electricity generation and address the environmental challenges posed by greenhouse gas emissions.

Econic Technologies Ltd. is a UK-based chemical technology company that specializes in developing innovative processes for producing polymers and polyurethanes using carbon dioxide and epoxides. Founded in 2011 and located in Macclesfield, the company focuses on transforming waste CO2 into valuable materials through advanced catalyst chemistry. Its product offerings include polycarbonates and polycarbonate polyols, which find applications in various sectors such as mattresses, home insulation, footwear, packaging, and construction. The company’s technology not only reduces dependence on fossil fuels but also aims to provide environmental benefits by mitigating greenhouse gas emissions. With a team of skilled scientists and engineers operating from a state-of-the-art facility at Alderley Park, Econic Technologies is committed to advancing sustainable practices in the plastics industry while fostering economic growth.

AccelerComm Ltd specializes in providing Forward Error Correction (FEC) solutions for various communication markets, including mobile handsets, base stations, and satellite standards. Founded in 2016 and based in Southampton, United Kingdom, the company focuses on enhancing the performance of next-generation wireless communications, addressing challenges such as noise, interference, and weak signal strength. Its product offerings include a range of encoding and decoding technologies, such as Polar, Turbo, and LDPC (Low-Density Parity-Check) decoders, specifically designed to meet 3GPP compliance. By delivering innovative semiconductor IP-core products, AccelerComm aims to facilitate optimal performance in digital communications while supporting the evolving needs of the industry.

Bramble Energy Ltd. is a London-based company that specializes in the design, development, and manufacture of printed circuit board (PCB) fuel cells, specifically proton exchange membrane fuel cells (PEMFCs). Incorporated in 2015, it leverages the capabilities of the global PCB industry to produce high-performance, cost-effective fuel cell stacks. The company's product lineup includes modular PCBFC stacks, ranging from 20 W to 5 kW, as well as custom-designed solutions. Bramble Energy serves various sectors, including stationary, portable, and automotive applications, aiming to provide gigawatts of fuel cell hardware. By utilizing innovative manufacturing methods and materials, the company enables clients to reduce energy consumption and lower their carbon footprints.

Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

IBEX Innovations Limited specializes in developing and commercializing advanced X-ray detector technology that provides high sensitivity materials information using standard X-ray systems. Founded in 2010 by Dr. Gary Gibson and based in Sedgefield, United Kingdom, the company has created the IBEX multi absorption plate (MAP) technology, which enhances traditional detectors by integrating materials information while maintaining key performance characteristics like speed and spatial resolution. IBEX's solutions are utilized across various sectors, including healthcare for bone mineral density assessment, electronics inspection, food safety, and security applications. The company collaborates with academic institutions, such as the Mathematics Department at Durham University, and maintains partnerships with healthcare organizations to validate its technology in medical imaging. Supported by venture capital and grants, IBEX Innovations continues to advance its technology to transform standard X-ray imaging into powerful diagnostic tools.

Mixergy Ltd, founded in 2014 and based in Cassington, United Kingdom, specializes in the development of energy storage equipment, particularly hot water tanks. The company aims to provide cost-effective solutions that enhance energy efficiency and support the integration of renewable energy sources. By optimizing the use of solar photovoltaic systems and heat pumps, Mixergy tanks contribute to grid balancing, promoting greater utilization of renewable power generation.

WaveOptics, Ltd. is a designer and manufacturer of advanced augmented reality display technology, specializing in diffractive waveguides for wearable devices. Founded in 2014 and based in Abingdon-on-Thames, United Kingdom, the company focuses on creating optical components that enhance the augmented reality experience. Their patented technology utilizes waveguide hologram physics and photonic crystals, allowing for lightweight, high field-of-view displays in full RGB color. By employing thin transparent substrates embedded with nanostructures, WaveOptics' devices manipulate light to generate images without the need for bulkier components traditionally used in AR systems. The company has established strategic partnerships with industry leaders such as Compal, Wistron, and Plessey to further its mission in the augmented reality market.

IBEX Innovations Limited specializes in developing and commercializing advanced X-ray detector technology that provides high sensitivity materials information using standard X-ray systems. Founded in 2010 by Dr. Gary Gibson and based in Sedgefield, United Kingdom, the company has created the IBEX multi absorption plate (MAP) technology, which enhances traditional detectors by integrating materials information while maintaining key performance characteristics like speed and spatial resolution. IBEX's solutions are utilized across various sectors, including healthcare for bone mineral density assessment, electronics inspection, food safety, and security applications. The company collaborates with academic institutions, such as the Mathematics Department at Durham University, and maintains partnerships with healthcare organizations to validate its technology in medical imaging. Supported by venture capital and grants, IBEX Innovations continues to advance its technology to transform standard X-ray imaging into powerful diagnostic tools.

Inivata Limited is a clinical cancer genomics company based in Cambridge, United Kingdom, established in 2014. The company specializes in the analysis of circulating tumor DNA (ctDNA) to enhance cancer testing and treatment for oncologists and their patients. Inivata's innovative approach utilizes TAm-Seq technology to detect and analyze genomic material from a patient's cell-free ctDNA, collected through non-invasive blood samples, known as liquid biopsies. This method revolutionizes cancer detection and monitoring by providing a less invasive alternative to traditional biopsies. The company's focus is on enabling clinicians to make more informed treatment decisions by monitoring response to therapies and detecting potential relapses in cancer patients. Inivata has also formed a strategic collaboration with NeoGenomics, Inc.

AccelerComm Ltd specializes in providing Forward Error Correction (FEC) solutions for various communication markets, including mobile handsets, base stations, and satellite standards. Founded in 2016 and based in Southampton, United Kingdom, the company focuses on enhancing the performance of next-generation wireless communications, addressing challenges such as noise, interference, and weak signal strength. Its product offerings include a range of encoding and decoding technologies, such as Polar, Turbo, and LDPC (Low-Density Parity-Check) decoders, specifically designed to meet 3GPP compliance. By delivering innovative semiconductor IP-core products, AccelerComm aims to facilitate optimal performance in digital communications while supporting the evolving needs of the industry.

C-Capture Limited, founded in 2008 and based in Leeds, United Kingdom, specializes in the development and design of solvent systems for the removal of carbon dioxide (CO2) from gas streams. The company utilizes its expertise in CO2-based chemistry and engineering to create absorbents for reversible CO2 capture, particularly in post-combustion processes. C-Capture focuses on providing non-toxic and economically viable carbon capture solutions for emission sources, including flue gases from power generators and hard-to-abate industries. By offering innovative technology for capturing CO2, C-Capture aims to contribute to more sustainable electricity generation and address the environmental challenges posed by greenhouse gas emissions.

WaveOptics, Ltd. is a designer and manufacturer of advanced augmented reality display technology, specializing in diffractive waveguides for wearable devices. Founded in 2014 and based in Abingdon-on-Thames, United Kingdom, the company focuses on creating optical components that enhance the augmented reality experience. Their patented technology utilizes waveguide hologram physics and photonic crystals, allowing for lightweight, high field-of-view displays in full RGB color. By employing thin transparent substrates embedded with nanostructures, WaveOptics' devices manipulate light to generate images without the need for bulkier components traditionally used in AR systems. The company has established strategic partnerships with industry leaders such as Compal, Wistron, and Plessey to further its mission in the augmented reality market.

Ultraleap Limited specializes in haptic control systems and 3D hand tracking technology, focusing on creating immersive user experiences. The company is recognized for its innovative haptic technology that utilizes ultrasound to generate tactile sensations in mid-air, allowing users to feel three-dimensional shapes and textures without physical contact. Its key products include the Leap Motion Controller, which tracks hand movements; the VR Developer Mount, designed for virtual reality applications; and the Gemini hand tracking platform. Ultraleap's solutions cater to a variety of industries, including extended reality, automotive, digital signage, industrial automation, consumer electronics, and location-based entertainment. Established in 2013 and headquartered in Bristol, United Kingdom, Ultraleap also has a subsidiary in Silicon Valley, United States. The company was previously known as Ultrahaptics until its rebranding in September 2019.

IBEX Innovations Limited specializes in developing and commercializing advanced X-ray detector technology that provides high sensitivity materials information using standard X-ray systems. Founded in 2010 by Dr. Gary Gibson and based in Sedgefield, United Kingdom, the company has created the IBEX multi absorption plate (MAP) technology, which enhances traditional detectors by integrating materials information while maintaining key performance characteristics like speed and spatial resolution. IBEX's solutions are utilized across various sectors, including healthcare for bone mineral density assessment, electronics inspection, food safety, and security applications. The company collaborates with academic institutions, such as the Mathematics Department at Durham University, and maintains partnerships with healthcare organizations to validate its technology in medical imaging. Supported by venture capital and grants, IBEX Innovations continues to advance its technology to transform standard X-ray imaging into powerful diagnostic tools.

Yoyo Wallet Limited is a mobile wallet company based in London, United Kingdom, that facilitates customer transactions for retailers, universities, and corporate locations. Founded in 2013 and originally known as JustYoyo Limited, the company rebranded in April 2015. Yoyo Wallet enables users to make payments using their smartphones, processing over 150,000 monthly in-store transactions by integrating payment and loyalty features through a simple scanning process. Additionally, it offers a marketing platform that enhances digital customer engagement for retailers, allowing them to deliver loyalty programs and rewards tailored to individual buying patterns.

Garrison Technology Limited, established in 2014 and located in London, specializes in cybersecurity solutions tailored for enterprise needs. The company has developed an innovative anti-malware product designed to protect organizations from significant cyber threats, particularly internet-borne targeted attacks. Garrison's technology addresses critical security challenges faced by enterprises and cloud computing, effectively mitigating risks associated with malware, phishing, and other web-borne threats. This solution allows users to securely access web content, ensuring safe browsing and secure data transfer while maintaining a high-quality user experience. Garrison aims to meet the increasing demands of the enterprise cybersecurity market by providing ultra-secure internet connectivity and scalable solutions.

Dukosi Ltd specializes in the design, development, and manufacturing of battery management systems, primarily targeting the automotive industry. Founded in 2003 and located in Edinburgh, United Kingdom, the company offers advanced cell sensor products for hybrid, plug-in hybrid, and electric vehicles, as well as electric bicycles and mobility vehicles. Dukosi's innovative solutions enable real-time monitoring of individual battery cell performance, enhancing the health and longevity of battery systems. Their products also contribute to the efficiency of smart grids, providing reliable and renewable energy solutions for various applications, including transport networks and residential use.

Artios Pharma Limited is a biotechnology company based in Cambridge, United Kingdom, that specializes in developing innovative cancer treatments targeting DNA damage response (DDR) pathways. Founded in 2015, the company is dedicated to creating first-in-class therapies aimed at selectively killing cancer cells. Artios's product pipeline features several promising programs, including a focus on DNA polymerase theta (Polθ), which plays a crucial role in DNA repair processes. Additionally, the company is advancing an in-licensed program that targets a newly identified protein linked to DDR and is developing a novel treatment aimed at DNA nucleases involved in these pathways. Artios collaborates with Cancer Research Technology and prominent DNA repair researchers globally to enhance its research and development efforts.

Spirea Ltd. is a healthcare technology company based in Harrogate, United Kingdom, that specializes in developing antibody drug conjugates (ADCs) for cancer treatment. Founded in 2015, Spirea has created a smart polymer platform designed for the controlled delivery of drug combinations, thereby maximizing the clinical efficacy of therapies. The company's innovative approach to ADCs allows for a greater amount of drug payload to be specifically targeted to tumor cells, resulting in enhanced therapeutic effects while significantly minimizing side effects. This development enables healthcare providers to offer well-tolerated treatment options for a variety of cancers, ultimately aiming to improve the quality of life for patients.

Enterprise Therapeutics Ltd. is a drug discovery company based in Brighton, United Kingdom, founded in 2014. It focuses on the research and development of innovative therapies for respiratory diseases, specifically targeting chronic obstructive pulmonary disease (COPD), cystic fibrosis, and asthma. The company aims to create disease-modifying therapies that address the underlying mechanisms of mucus congestion in the lungs, which can lead to breathing difficulties and increased susceptibility to lung infections. By developing these novel treatments, Enterprise Therapeutics seeks to enhance the quality of life for patients suffering from these chronic respiratory conditions.

Econic Technologies Ltd. is a UK-based chemical technology company that specializes in developing innovative processes for producing polymers and polyurethanes using carbon dioxide and epoxides. Founded in 2011 and located in Macclesfield, the company focuses on transforming waste CO2 into valuable materials through advanced catalyst chemistry. Its product offerings include polycarbonates and polycarbonate polyols, which find applications in various sectors such as mattresses, home insulation, footwear, packaging, and construction. The company’s technology not only reduces dependence on fossil fuels but also aims to provide environmental benefits by mitigating greenhouse gas emissions. With a team of skilled scientists and engineers operating from a state-of-the-art facility at Alderley Park, Econic Technologies is committed to advancing sustainable practices in the plastics industry while fostering economic growth.

Spirea Ltd. is a healthcare technology company based in Harrogate, United Kingdom, that specializes in developing antibody drug conjugates (ADCs) for cancer treatment. Founded in 2015, Spirea has created a smart polymer platform designed for the controlled delivery of drug combinations, thereby maximizing the clinical efficacy of therapies. The company's innovative approach to ADCs allows for a greater amount of drug payload to be specifically targeted to tumor cells, resulting in enhanced therapeutic effects while significantly minimizing side effects. This development enables healthcare providers to offer well-tolerated treatment options for a variety of cancers, ultimately aiming to improve the quality of life for patients.

Oxehealth Ltd. is a technology company based in Oxford, United Kingdom, that specializes in non-contact vital signs monitoring solutions. Founded in 2012, the company has developed the Oxecam software, which enables the measurement of heart rate, respiratory rate, and blood oxygenation using a digital video camera. This innovative system is particularly beneficial in healthcare settings, including mental health facilities and care homes, where staff may not always be present to monitor patients. Oxehealth's technology provides alerts for potentially risky activities and offers objective data for care planning, enhancing the ability of clinicians and caregivers to support vulnerable individuals. By employing advanced algorithms that utilize deep learning and computer vision, Oxehealth aims to improve patient monitoring and management while allowing staff more time for direct care. The company has achieved world-first certification for its software as a medical device, marking a significant advancement in remote patient monitoring.

Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Touchstone Innovations is a venture capital firm that focuses on creating, building, and investing in pioneering technology companies emerging from exceptional scientific research in the 'Golden Triangle' of London, Cambridge, and Oxford. Established in 1986, the firm employs a comprehensive strategy that encompasses the entire process from idea generation to intellectual property protection, company formation, seed funding, incubation, and scale-up. By providing continuous investment from start-up to scale-up, Touchstone Innovations supports scientists and entrepreneurs in commercializing their ideas through licensing and recruitment of top management teams. The firm has a proven track record of leveraging early-stage research into high-quality, well-managed businesses, maintaining active involvement with its portfolio companies throughout their lifecycle. With a commitment to de-risking investment, Touchstone Innovations has facilitated over £1.5 billion in funding to drive technological innovation in the UK. In 2017, the firm was acquired by IP Group plc, further expanding its capabilities in the investment landscape.

Eight19, located in Cambridge, UK, develops and manufactures plastic photovoltaics for energy harvesting, for the internet of things and for off-grid applications. Through the innovative use of industry-standard, high-volume, roll-to-roll processes and solution-based organic photoactive materials, the company has a highly cost-effective route for scaling-up its technology to supply the largest markets. Eight19 is currently producing modules on a small scale for commercial partners with applications in indoor energy harvesting for wireless sensor and controllers, signage and display, and outdoor power for portable electronics. Our plastic PV modules benefit from flexibility, thinness, light-weight and robustness.

Creavo Medical Technologies Ltd. is a UK-based medical device company focused on developing innovative diagnostic technologies for acute medical settings. Founded in 2014, the company aims to enhance patient care by providing a portable, battery-powered device that enables the detection of heart-related issues, specifically acute coronary syndromes and ischemia. This technology allows for magnetocardiography to be performed directly at the patient's bedside, facilitating timely diagnosis and treatment. Creavo Medical Technologies, which has facilities in Leeds and Coventry, was established by a group of experts in clinical research and business to commercialize advancements developed by Professor Ben Varcoe from Leeds University.

Alesi Surgical Ltd. specializes in the development and commercialization of laparoscopic surgical smoke handling systems aimed at enhancing the safety and outcomes of surgical procedures. Founded in 2009 and based in Cardiff, United Kingdom, the company emerged as a spin-out from the Welsh Institute for Minimal Access Therapy, benefiting from direct access to experienced surgeons and surgical trainers. Alesi Surgical's innovative products are designed to be portable and applicable in both laparoscopic and robot-assisted surgeries. Utilizing electrostatic precipitation technology, these tools effectively eliminate surgical smoke, ensuring a clear visual field during procedures. Alesi Surgical distributes its products to hospitals across Europe, the Middle East, New Zealand, and Australia.

Ultraleap Limited specializes in haptic control systems and 3D hand tracking technology, focusing on creating immersive user experiences. The company is recognized for its innovative haptic technology that utilizes ultrasound to generate tactile sensations in mid-air, allowing users to feel three-dimensional shapes and textures without physical contact. Its key products include the Leap Motion Controller, which tracks hand movements; the VR Developer Mount, designed for virtual reality applications; and the Gemini hand tracking platform. Ultraleap's solutions cater to a variety of industries, including extended reality, automotive, digital signage, industrial automation, consumer electronics, and location-based entertainment. Established in 2013 and headquartered in Bristol, United Kingdom, Ultraleap also has a subsidiary in Silicon Valley, United States. The company was previously known as Ultrahaptics until its rebranding in September 2019.

Dukosi Ltd specializes in the design, development, and manufacturing of battery management systems, primarily targeting the automotive industry. Founded in 2003 and located in Edinburgh, United Kingdom, the company offers advanced cell sensor products for hybrid, plug-in hybrid, and electric vehicles, as well as electric bicycles and mobility vehicles. Dukosi's innovative solutions enable real-time monitoring of individual battery cell performance, enhancing the health and longevity of battery systems. Their products also contribute to the efficiency of smart grids, providing reliable and renewable energy solutions for various applications, including transport networks and residential use.

Parkwalk Advisors Ltd is a London-based venture capital firm established in 2009, specializing in investments in early and growth-stage technology companies, particularly those spun out from UK universities and research institutions. The firm focuses on sectors such as healthcare, energy, materials, artificial intelligence, big data, cleantech, medtech, and quantum computing. Parkwalk seeks to invest in companies with strong intellectual property and a clear path to market, typically committing between £250,000 and £10 million per investment. The firm is stage agnostic, engaging in various rounds of funding, including seed and Series C and beyond. It emphasizes investments in unquoted companies and aims to generate capital gains for its investors, benefiting from favorable tax relief programs in the UK. Parkwalk leverages extensive networks in academia and venture capital to access high-quality deal flow. In 2017, Parkwalk became a subsidiary of IP Group Plc, enhancing its capabilities in intellectual property commercialization.

Oxford Nanopore Technologies is a biotechnology company specializing in nanopore-based sequencing technology for analyzing DNA, RNA, proteins, and small molecules. Its diverse product line includes the portable MinION device, the benchtop PromethION, the GridION system, and Flongle, which caters to on-demand sequencing needs. The technology enables real-time data streaming and is applicable across various fields such as human genomics, cancer research, microbiology, plant science, and environmental studies. Additionally, Oxford Nanopore's products support rapid and accessible molecular analysis, making them suitable for both laboratory and field use. The company's innovations are backed by a robust patent portfolio and are utilized in over 80 countries, addressing needs in healthcare, agriculture, and education. Founded in 2005 and headquartered in Oxford, United Kingdom, Oxford Nanopore also maintains offices in several other countries, enhancing its global reach in advancing genomic research and applications.

Cambridge Innovation Capital Limited is a venture capital firm based in Cambridge, United Kingdom, that focuses on early-stage, startup, and mid-venture investments in life sciences and technology sectors. Established in 2013, the firm specializes in backing companies affiliated with the University of Cambridge and the surrounding innovation ecosystem. Its investment portfolio includes businesses in therapeutics, medtech, diagnostics, digital health, genomics, proteomics, and high-growth technology sectors such as artificial intelligence and quantum technologies. Cambridge Innovation Capital typically invests up to £19 million in each portfolio company, leveraging its strong connections within the Cambridge Cluster to identify and support disruptive, deep-tech ventures. Since its inception, the firm has raised £275 million to fuel innovation and growth in these high-potential areas.

Mirriad Advertising PLC operates an in-content advertising platform that leverages artificial intelligence and computer vision technology to dynamically insert products and innovative signage into video content post-production. This method allows advertisers to integrate their offerings seamlessly into existing media, enhancing viewer engagement without interrupting the viewing experience. Mirriad's technology creates new advertising inventory, providing additional revenue opportunities for content producers and distributors while improving overall viewer satisfaction by minimizing commercial interruptions. The company primarily generates revenue from the United States and has a presence in Europe and China.

Navenio Limited is a software technology company based in Oxford, United Kingdom, that specializes in location-based services for indoor environments. Founded in 2015, Navenio offers a mobile application solution that enhances indoor localization by enabling the tracking of individuals without the need for additional hardware, such as beacons or Wi-Fi. This innovative approach utilizes fingerprinting of the electromagnetic spectrum, sensor data, and indoor mapping to provide accurate location monitoring across various sectors, including retail, transportation, venues, and healthcare. Navenio's intelligent workforce solution significantly improves operational efficiency and workflow by automating processes based on real-world best practices.

Mixergy Ltd, founded in 2014 and based in Cassington, United Kingdom, specializes in the development of energy storage equipment, particularly hot water tanks. The company aims to provide cost-effective solutions that enhance energy efficiency and support the integration of renewable energy sources. By optimizing the use of solar photovoltaic systems and heat pumps, Mixergy tanks contribute to grid balancing, promoting greater utilization of renewable power generation.

Ultraleap Limited specializes in haptic control systems and 3D hand tracking technology, focusing on creating immersive user experiences. The company is recognized for its innovative haptic technology that utilizes ultrasound to generate tactile sensations in mid-air, allowing users to feel three-dimensional shapes and textures without physical contact. Its key products include the Leap Motion Controller, which tracks hand movements; the VR Developer Mount, designed for virtual reality applications; and the Gemini hand tracking platform. Ultraleap's solutions cater to a variety of industries, including extended reality, automotive, digital signage, industrial automation, consumer electronics, and location-based entertainment. Established in 2013 and headquartered in Bristol, United Kingdom, Ultraleap also has a subsidiary in Silicon Valley, United States. The company was previously known as Ultrahaptics until its rebranding in September 2019.

Dukosi Ltd specializes in the design, development, and manufacturing of battery management systems, primarily targeting the automotive industry. Founded in 2003 and located in Edinburgh, United Kingdom, the company offers advanced cell sensor products for hybrid, plug-in hybrid, and electric vehicles, as well as electric bicycles and mobility vehicles. Dukosi's innovative solutions enable real-time monitoring of individual battery cell performance, enhancing the health and longevity of battery systems. Their products also contribute to the efficiency of smart grids, providing reliable and renewable energy solutions for various applications, including transport networks and residential use.

Oxford Nanopore Technologies is a biotechnology company specializing in nanopore-based sequencing technology for analyzing DNA, RNA, proteins, and small molecules. Its diverse product line includes the portable MinION device, the benchtop PromethION, the GridION system, and Flongle, which caters to on-demand sequencing needs. The technology enables real-time data streaming and is applicable across various fields such as human genomics, cancer research, microbiology, plant science, and environmental studies. Additionally, Oxford Nanopore's products support rapid and accessible molecular analysis, making them suitable for both laboratory and field use. The company's innovations are backed by a robust patent portfolio and are utilized in over 80 countries, addressing needs in healthcare, agriculture, and education. Founded in 2005 and headquartered in Oxford, United Kingdom, Oxford Nanopore also maintains offices in several other countries, enhancing its global reach in advancing genomic research and applications.

Anacail Limited is a technology company based in Glasgow, United Kingdom, that specializes in the generation of ozone within sealed packages to effectively eliminate surface contaminants and microorganisms. The company's innovative in-pack ozone system includes an ozone head that produces intense electric fields to create plasma and generate ozone after the packaging has been sealed. This technology not only enhances food safety by providing rapid and chemical-free sterilization but also eliminates the handling and safety concerns typically associated with ozone use. Anacail develops equipment for food processing lines to generate sterilizing ozone and devices aimed at medical sterilization, ensuring a decontaminated package and contents without residual chemicals. Established in 2010, Anacail is focused on delivering safe and efficient sterilization solutions.

Dukosi Ltd specializes in the design, development, and manufacturing of battery management systems, primarily targeting the automotive industry. Founded in 2003 and located in Edinburgh, United Kingdom, the company offers advanced cell sensor products for hybrid, plug-in hybrid, and electric vehicles, as well as electric bicycles and mobility vehicles. Dukosi's innovative solutions enable real-time monitoring of individual battery cell performance, enhancing the health and longevity of battery systems. Their products also contribute to the efficiency of smart grids, providing reliable and renewable energy solutions for various applications, including transport networks and residential use.

Eight19, located in Cambridge, UK, develops and manufactures plastic photovoltaics for energy harvesting, for the internet of things and for off-grid applications. Through the innovative use of industry-standard, high-volume, roll-to-roll processes and solution-based organic photoactive materials, the company has a highly cost-effective route for scaling-up its technology to supply the largest markets. Eight19 is currently producing modules on a small scale for commercial partners with applications in indoor energy harvesting for wireless sensor and controllers, signage and display, and outdoor power for portable electronics. Our plastic PV modules benefit from flexibility, thinness, light-weight and robustness.

Ultraleap Limited specializes in haptic control systems and 3D hand tracking technology, focusing on creating immersive user experiences. The company is recognized for its innovative haptic technology that utilizes ultrasound to generate tactile sensations in mid-air, allowing users to feel three-dimensional shapes and textures without physical contact. Its key products include the Leap Motion Controller, which tracks hand movements; the VR Developer Mount, designed for virtual reality applications; and the Gemini hand tracking platform. Ultraleap's solutions cater to a variety of industries, including extended reality, automotive, digital signage, industrial automation, consumer electronics, and location-based entertainment. Established in 2013 and headquartered in Bristol, United Kingdom, Ultraleap also has a subsidiary in Silicon Valley, United States. The company was previously known as Ultrahaptics until its rebranding in September 2019.

Intelligent Ultrasound is a company that specializes in developing software and training simulators for medical ultrasound applications. Its product offerings include a range of AI-based software solutions like ScanNav Audit, which supports ultrasound practitioners during fetal anomaly scans, and ScanNav AutoCapture, which automatically captures images during ultrasound procedures. The company also provides simulation training platforms such as ScanTrainer, a haptic simulator for obstetrics and gynecology, and HeartWorks, a manikin-based simulator for cardiac and anesthesiology training. These products aim to enhance the quality, reliability, and diagnostic capabilities of ultrasound imaging, ultimately reducing the risk of misdiagnoses. Founded in 2004 and headquartered in Cardiff, the United Kingdom, Intelligent Ultrasound operates in key markets including the UK, North America, and internationally. The company was previously known as MedaPhor Group plc until its rebranding in 2019.

Perpetuum Ltd. specializes in the engineering, manufacturing, and commercialization of electromagnetic vibration harvesting micro generators. Founded in 2004 and based in Southampton, United Kingdom, the company focuses on creating battery-free vibration energy harvesters and wireless sensor nodes for various applications, including rail, oil and gas, chemicals, power generation, and water treatment. Perpetuum's technology converts mechanical vibrations into electrical energy, enabling autonomous, maintenance-free wireless sensors that monitor equipment conditions and processes. This innovative approach enhances efficiency and safety in fleet management and services, particularly within the rail industry. As a technology spin-off from the University of Southampton, Perpetuum has established itself as a leader in vibration energy harvesting, providing practical solutions for wireless automation.

Blooie Limited operates an intelligent conversation platform designed to enhance real-time engagement between businesses and their online customers. Founded in 2011 and based in Newcastle upon Tyne, United Kingdom, Blooie enables websites to facilitate conversations among users who share an interest in the content they encounter. The platform provides business owners with tools to engage in informed discussions, track conversions through detailed analytics, and maintain user interaction on their sites. By allowing users to chat with both business representatives and other customers, as well as connect with friends on social media, Blooie aims to improve customer satisfaction and drive conversions for online businesses.

Oxford Nanopore Technologies is a biotechnology company specializing in nanopore-based sequencing technology for analyzing DNA, RNA, proteins, and small molecules. Its diverse product line includes the portable MinION device, the benchtop PromethION, the GridION system, and Flongle, which caters to on-demand sequencing needs. The technology enables real-time data streaming and is applicable across various fields such as human genomics, cancer research, microbiology, plant science, and environmental studies. Additionally, Oxford Nanopore's products support rapid and accessible molecular analysis, making them suitable for both laboratory and field use. The company's innovations are backed by a robust patent portfolio and are utilized in over 80 countries, addressing needs in healthcare, agriculture, and education. Founded in 2005 and headquartered in Oxford, United Kingdom, Oxford Nanopore also maintains offices in several other countries, enhancing its global reach in advancing genomic research and applications.

Diurnal Group plc is a specialty pharmaceutical company based in Cardiff, United Kingdom, that focuses on developing hormone therapeutics for chronic endocrine conditions. Founded in 2004, the company offers innovative treatments such as Alkindi, a replacement therapy for pediatric adrenal insufficiency in Europe. Diurnal is also advancing its product pipeline with Chronocort, which has completed Phase III clinical trials for congenital adrenal hyperplasia and adrenal insufficiency. Additionally, the company's early-stage pipeline includes Native Oral Testosterone for hypogonadism, a short interfering RNA therapy for adrenocorticotropin-dependent Cushing's syndrome, and a modified-release preparation of T3 hormone for hypothyroidism. Diurnal's research is centered on circadian-based endocrinology, aimed at providing effective and long-term solutions for patients with rare and chronic endocrine disorders.

Givey Limited operates givey.com, a fee-free online community funding platform dedicated to raising donations for small charities and local communities in the UK. The platform enables users to create fundraising pages that can feature photos, videos, and links from various social media networks, facilitating easy sharing and engagement. It empowers businesses to support their employees' charitable efforts and allows charities to manage their fundraising activities effectively, including overseeing donations and communicating with supporters. With over 7,000 registered charities and a growing user base of more than 100,000 individuals, Givey enhances the digital presence of small charities and local non-profit groups, promoting social good and fostering community resilience. Founded in 1994 and based in London, Givey is committed to making charitable giving more accessible and impactful.

Seren Photonics Ltd has developed a manufacturing procedure that greatly increases the intensity of light generated at the heart of a HBLED at negligable cost to the manufacturer. The technology has been applied to standard HBLED structures and so far has demonstrated between 100% to 900% increase in light generation compared to unprocessed diodes. The technology is based on the work of Dr Tao Wang and the EPSRC National III-V Centre attached to the School of Engineering, University of Sheffield.

Oxehealth Ltd. is a technology company based in Oxford, United Kingdom, that specializes in non-contact vital signs monitoring solutions. Founded in 2012, the company has developed the Oxecam software, which enables the measurement of heart rate, respiratory rate, and blood oxygenation using a digital video camera. This innovative system is particularly beneficial in healthcare settings, including mental health facilities and care homes, where staff may not always be present to monitor patients. Oxehealth's technology provides alerts for potentially risky activities and offers objective data for care planning, enhancing the ability of clinicians and caregivers to support vulnerable individuals. By employing advanced algorithms that utilize deep learning and computer vision, Oxehealth aims to improve patient monitoring and management while allowing staff more time for direct care. The company has achieved world-first certification for its software as a medical device, marking a significant advancement in remote patient monitoring.

Creavo Medical Technologies Ltd. is a UK-based medical device company focused on developing innovative diagnostic technologies for acute medical settings. Founded in 2014, the company aims to enhance patient care by providing a portable, battery-powered device that enables the detection of heart-related issues, specifically acute coronary syndromes and ischemia. This technology allows for magnetocardiography to be performed directly at the patient's bedside, facilitating timely diagnosis and treatment. Creavo Medical Technologies, which has facilities in Leeds and Coventry, was established by a group of experts in clinical research and business to commercialize advancements developed by Professor Ben Varcoe from Leeds University.

Fusion IP owns the rights to 100% of university-owned research generated at two of the UK's leading universities - The University of Sheffield and Cardiff University. These exclusive partnerships enable us to develop some of the world's most advanced and exciting science, in fields as varied as clean energy, electronics, engineering and medicine; turning world class research into valuable businesses through the creation of portfolio of companies.

Blooie Limited operates an intelligent conversation platform designed to enhance real-time engagement between businesses and their online customers. Founded in 2011 and based in Newcastle upon Tyne, United Kingdom, Blooie enables websites to facilitate conversations among users who share an interest in the content they encounter. The platform provides business owners with tools to engage in informed discussions, track conversions through detailed analytics, and maintain user interaction on their sites. By allowing users to chat with both business representatives and other customers, as well as connect with friends on social media, Blooie aims to improve customer satisfaction and drive conversions for online businesses.

Exonate is a privately held, early stage, biotech company spun out of the University of Nottingham that is focused on alternative splicing of Vascular Endothelial Growth Factor (VEGF) in ophthalmology. Exonate’s lead programme is focused on Diabetic Macular Oedema (DMO). A consequence of diabetic retinopathy, DMO, is swelling in an area of the retina called the macula and wet Age-Related Macular Degeneration (wAMD), which is the leading cause of vision loss in people aged 60 and older. The Company is founded on scientific excellence with strong links to Professor David Bates and his lab at Nottingham University specializing in the biology and biochemical pathways of VEGF splice variants. Exonate have developed small molecules that inhibit production of pro-angiogenic VEGF through selective inhibition of serine/threonine-protein kinase 1 (SRPK1)-mediated VEGF splicing. These inhibitors have already demonstrated superior efficacy as topical agents in preclinical models of wet AMD. Through a Wellcome Trust funded project, Exonate has completed an optimization programme and has nominated a pre-clinical candidate drug with optimal characteristics. During the second quarter of 2020 regulatory toxicology and safety pharmacology studies have taken place. This is to support the successful application to the regulatory authorities for clinical evaluation. Exonate is led by an experienced, international management team that has previously worked together with cross-disciplinary experience in medicine and drug development, as well as successful fundraising for early stage companies. About Diabetic Macular Oedema (DMO)*: DMO is the build-up of fluid (Oedema) in a region of the retina called the macula. The macula is important for the sharp, straight-ahead vision that is used for reading, recognizing faces, and driving. DMO is the most common cause of vision loss among people with diabetic retinopathy. About half of all people with diabetic retinopathy will develop DMO and although it is more likely to occur as diabetic retinopathy worsens, DMO can happen at any stage of the disease. About wet Age-Related Macular Degeneration (wet AMD): Today, wet AMD is a leading cause of vision loss in people aged 60 years or older and affects more than 30 million patients worldwide, over 200,000 of those in the UK alone. If untreated patients are likely to lose sight in the affected eye within 24 months of disease onset. The main currently available treatment options for DMO and wet AMD are: • anti-VEGF antibody drugs – to prevent the growth of new blood vessels in the eye. Unlike small molecule drugs or eye drops these treatments must be injected into the eye once every 1 or 2 months. Resistance can develop to these drugs causing the disease to progress anew. • Laser surgery – to destroy abnormal blood vessels in the eye. This type of surgery is only suitable if blood vessel damage is not too extensive and if the abnormal blood vessels aren't close to the fovea, as performing surgery close to this part of the eye can cause permanent vision loss. • With DMO, Corticosteroids either injected or implanted into the eye, may be used alone or in combination with other drugs or laser surgery to treat DMO. *source: https://nei.nih.gov/health/diabetic/retinopathy

Verticly is a London-based company that offers a SaaS platform designed to facilitate personalized engagement for FMCG brands, retailers, and manufacturers. Founded in 2014, it specializes in connecting online and offline customer data to provide real-time content tailored to consumers. The platform supports various marketing solutions in the omni-channel landscape, including channel attribution, vouchering, and personalized messaging. By streamlining the online-to-offline marketing process, Verticly aims to enhance customer experiences and drive purchasing decisions for small and medium enterprises.

Oxford Nanopore Technologies is a biotechnology company specializing in nanopore-based sequencing technology for analyzing DNA, RNA, proteins, and small molecules. Its diverse product line includes the portable MinION device, the benchtop PromethION, the GridION system, and Flongle, which caters to on-demand sequencing needs. The technology enables real-time data streaming and is applicable across various fields such as human genomics, cancer research, microbiology, plant science, and environmental studies. Additionally, Oxford Nanopore's products support rapid and accessible molecular analysis, making them suitable for both laboratory and field use. The company's innovations are backed by a robust patent portfolio and are utilized in over 80 countries, addressing needs in healthcare, agriculture, and education. Founded in 2005 and headquartered in Oxford, United Kingdom, Oxford Nanopore also maintains offices in several other countries, enhancing its global reach in advancing genomic research and applications.

Ubiquigent Limited is a biotechnology company based in Dundee, United Kingdom, founded in 2009. It specializes in the development and supply of high-quality reagents, kits, and drug discovery assay development services, primarily targeting the life science research community. Ubiquigent focuses on protein degradation and the ubiquitin signaling systems, providing services that support drug discovery efforts aimed at developing novel deubiquitylase (DUB) enzyme inhibitors. The company works closely with academic researchers and pharmaceutical scientists, aiding in the exploration of therapeutic applications for DUB modulators in areas with significant unmet medical needs. Ubiquigent is committed to generating intellectual property through its innovative drug discovery programs, which include optimizing compounds that target the ubiquitin cascade.

Blooie Limited operates an intelligent conversation platform designed to enhance real-time engagement between businesses and their online customers. Founded in 2011 and based in Newcastle upon Tyne, United Kingdom, Blooie enables websites to facilitate conversations among users who share an interest in the content they encounter. The platform provides business owners with tools to engage in informed discussions, track conversions through detailed analytics, and maintain user interaction on their sites. By allowing users to chat with both business representatives and other customers, as well as connect with friends on social media, Blooie aims to improve customer satisfaction and drive conversions for online businesses.

Xeros Ltd. is a new company focused on the development of "virtually waterless" laundry cleaning. Harnessing over 30 years of research by Professor Stephen Burkinshaw and the University of Leeds, Xeros is the brand name for a patented polymer based cleaning that creates step change advantage in the cost and environmental impact of aqueous wash cleaning.

Givey Limited operates givey.com, a fee-free online community funding platform dedicated to raising donations for small charities and local communities in the UK. The platform enables users to create fundraising pages that can feature photos, videos, and links from various social media networks, facilitating easy sharing and engagement. It empowers businesses to support their employees' charitable efforts and allows charities to manage their fundraising activities effectively, including overseeing donations and communicating with supporters. With over 7,000 registered charities and a growing user base of more than 100,000 individuals, Givey enhances the digital presence of small charities and local non-profit groups, promoting social good and fostering community resilience. Founded in 1994 and based in London, Givey is committed to making charitable giving more accessible and impactful.

Magnomatics is a high technology spin-out company from the largest electrical machines research group in the UK. Magnomatics was established in 2006 as a spin-out from the University of Sheffield to commercialise ground-breaking research on magnetic transmission systems, high-torque electrical machines and electromechanical actuators and dampers being undertaken by Dr Kais Atallah and Professor David Howe in the Electrical Machines and Drives research group at the University.

Fantoo is a productivity application designed for both mobile and desktop platforms, focused on enhancing workplace efficiency. Founded in 2012 and headquartered in Bracknell, United Kingdom, Fantoo integrates various web applications, messaging services, and notifications into a single interface. The platform leverages artificial intelligence to organize emails and streamline workflows, helping users manage tasks and appointments more effectively. By emphasizing important messages and facilitating action, Fantoo provides users with a centralized hub that minimizes distractions and maximizes collaboration. Its design combines cognitive theory with advanced technology, aiming to transform how individuals and teams communicate and work together.

Oxehealth Ltd. is a technology company based in Oxford, United Kingdom, that specializes in non-contact vital signs monitoring solutions. Founded in 2012, the company has developed the Oxecam software, which enables the measurement of heart rate, respiratory rate, and blood oxygenation using a digital video camera. This innovative system is particularly beneficial in healthcare settings, including mental health facilities and care homes, where staff may not always be present to monitor patients. Oxehealth's technology provides alerts for potentially risky activities and offers objective data for care planning, enhancing the ability of clinicians and caregivers to support vulnerable individuals. By employing advanced algorithms that utilize deep learning and computer vision, Oxehealth aims to improve patient monitoring and management while allowing staff more time for direct care. The company has achieved world-first certification for its software as a medical device, marking a significant advancement in remote patient monitoring.

Karus Therapeutics Limited is a biopharmaceutical company based in Oxfordshire, United Kingdom, focused on developing innovative small molecule drugs for cancer treatment. Established in 2005, the company specializes in orally-active drugs that target specific molecular pathways. Its portfolio includes KA2237, a dual-selective inhibitor of PI3K isoforms p110ß and p110d, aimed at treating both hematological and solid tumors, and KA2507, which targets HDAC6 for PD-L1 expressing tumors. Karus Therapeutics combines targeted therapies with immunotherapeutic activity, enabling effective treatment of a variety of cancers as well as immune and inflammatory disorders.

MedaPhor Limited, an e-learning company, produces training products for postgraduate medical professionals. The company offers tutorials for learning or improving ultrasound examination techniques; and simulation technology solutions for medical education and training. Its solutions include Blue Phantom, which offers ultrasound phantoms for hands-on gynaecological and obstetrics simulation training; True Anatomy, an endovaginal training model for ultrasound simulation training; and intrauterine pregnancy, ectopic pregnancy, and general pathology models. The company was incorporated in 2004 and is based in Cardiff, the United Kingdom.

Itaconix plc is a manufacturer of bio-based polymers derived from itaconic acid, serving the home care, personal care, and industrial markets primarily in North America and Europe. The company's product offerings include a range of water-soluble polymers such as Itaconix TSI, DSP, CHT, and VELASOFT, which are utilized in cleaning, hygiene, surface coatings, and agricultural applications. Additionally, Itaconix produces odor-neutralizing agents like Itaconix ZINADOR and personal care ingredients such as VELAFRESH fixating complexes. The company has developed proprietary technologies that enhance product performance while promoting sustainability. Founded in 2012 and headquartered in Stratham, New Hampshire, Itaconix continues to innovate and expand its product pipeline to meet the evolving needs of various industries.

Oxford Nanopore Technologies is a biotechnology company specializing in nanopore-based sequencing technology for analyzing DNA, RNA, proteins, and small molecules. Its diverse product line includes the portable MinION device, the benchtop PromethION, the GridION system, and Flongle, which caters to on-demand sequencing needs. The technology enables real-time data streaming and is applicable across various fields such as human genomics, cancer research, microbiology, plant science, and environmental studies. Additionally, Oxford Nanopore's products support rapid and accessible molecular analysis, making them suitable for both laboratory and field use. The company's innovations are backed by a robust patent portfolio and are utilized in over 80 countries, addressing needs in healthcare, agriculture, and education. Founded in 2005 and headquartered in Oxford, United Kingdom, Oxford Nanopore also maintains offices in several other countries, enhancing its global reach in advancing genomic research and applications.

Seren Photonics Ltd has developed a manufacturing procedure that greatly increases the intensity of light generated at the heart of a HBLED at negligable cost to the manufacturer. The technology has been applied to standard HBLED structures and so far has demonstrated between 100% to 900% increase in light generation compared to unprocessed diodes. The technology is based on the work of Dr Tao Wang and the EPSRC National III-V Centre attached to the School of Engineering, University of Sheffield.

TheySay, an Oxford University, UK-based sentiment analysis start-up. TheySay’s core product is AffectR, a platform that employs a deep linguistic approach allowing it to interpret sentiment computationally.It can extract the sentiment portrayed towards a specified entity in a given passage of text.

Givey Limited operates givey.com, a fee-free online community funding platform dedicated to raising donations for small charities and local communities in the UK. The platform enables users to create fundraising pages that can feature photos, videos, and links from various social media networks, facilitating easy sharing and engagement. It empowers businesses to support their employees' charitable efforts and allows charities to manage their fundraising activities effectively, including overseeing donations and communicating with supporters. With over 7,000 registered charities and a growing user base of more than 100,000 individuals, Givey enhances the digital presence of small charities and local non-profit groups, promoting social good and fostering community resilience. Founded in 1994 and based in London, Givey is committed to making charitable giving more accessible and impactful.

Blooie Limited operates an intelligent conversation platform designed to enhance real-time engagement between businesses and their online customers. Founded in 2011 and based in Newcastle upon Tyne, United Kingdom, Blooie enables websites to facilitate conversations among users who share an interest in the content they encounter. The platform provides business owners with tools to engage in informed discussions, track conversions through detailed analytics, and maintain user interaction on their sites. By allowing users to chat with both business representatives and other customers, as well as connect with friends on social media, Blooie aims to improve customer satisfaction and drive conversions for online businesses.

Blooie Limited operates an intelligent conversation platform designed to enhance real-time engagement between businesses and their online customers. Founded in 2011 and based in Newcastle upon Tyne, United Kingdom, Blooie enables websites to facilitate conversations among users who share an interest in the content they encounter. The platform provides business owners with tools to engage in informed discussions, track conversions through detailed analytics, and maintain user interaction on their sites. By allowing users to chat with both business representatives and other customers, as well as connect with friends on social media, Blooie aims to improve customer satisfaction and drive conversions for online businesses.

Givey Limited operates givey.com, a fee-free online community funding platform dedicated to raising donations for small charities and local communities in the UK. The platform enables users to create fundraising pages that can feature photos, videos, and links from various social media networks, facilitating easy sharing and engagement. It empowers businesses to support their employees' charitable efforts and allows charities to manage their fundraising activities effectively, including overseeing donations and communicating with supporters. With over 7,000 registered charities and a growing user base of more than 100,000 individuals, Givey enhances the digital presence of small charities and local non-profit groups, promoting social good and fostering community resilience. Founded in 1994 and based in London, Givey is committed to making charitable giving more accessible and impactful.

Oxford Nanopore Technologies is a biotechnology company specializing in nanopore-based sequencing technology for analyzing DNA, RNA, proteins, and small molecules. Its diverse product line includes the portable MinION device, the benchtop PromethION, the GridION system, and Flongle, which caters to on-demand sequencing needs. The technology enables real-time data streaming and is applicable across various fields such as human genomics, cancer research, microbiology, plant science, and environmental studies. Additionally, Oxford Nanopore's products support rapid and accessible molecular analysis, making them suitable for both laboratory and field use. The company's innovations are backed by a robust patent portfolio and are utilized in over 80 countries, addressing needs in healthcare, agriculture, and education. Founded in 2005 and headquartered in Oxford, United Kingdom, Oxford Nanopore also maintains offices in several other countries, enhancing its global reach in advancing genomic research and applications.

Crysalin Limited, founded in June 2007 in London, focuses on the research and development of crysalin lattice technology, which originated from patented work at Oxford University. The company specializes in crysalins, a protein-based nanotechnology that significantly enhances protein structure determination, particularly for challenging macromolecular targets such as membrane proteins and flexible soluble proteins. By imposing order on these targets, crysalins enable advanced imaging techniques like X-ray crystallography and electron microscopy to resolve three-dimensional molecular structures that other methods cannot. In addition to protein structure determination, Crysalin's technology holds promise for applications in biosensor development and optoelectronics, positioning the company as a key player in the field of biophysical research and nanotechnology.