Intersouth Partners

Intersouth Partners is a venture capital firm based in Durham, North Carolina, established in 1985. The firm specializes in seed and early-stage investments, primarily within the technology and life sciences sectors. In technology, Intersouth focuses on areas such as software, semiconductors, communications, digital media, clean technology, and security. In the life sciences domain, its investment interests include medical devices, biopharmaceuticals, agricultural biotechnology, and biomaterials. The firm typically avoids sectors like airline, apparel, broadcasting, consumer products, energy, entertainment, environmental, industrial, manufacturing, oil and gas, publishing, real estate, and restaurants. Intersouth seeks to invest between $0.5 million and $8 million in companies located across the Southeast, particularly in the region from Baltimore to Florida, and aims for total investments averaging $12 million through various financing rounds. The firm prefers to obtain a board seat in its portfolio companies and typically looks to exit investments within two to six years. With a track record of investing in over 100 private companies, Intersouth Partners is recognized as one of the largest venture capital firms in North Carolina and the Southeast.