Entrepreneur First

Entrepreneur First is a London-based venture capital firm established in 2011, with offices in five cities across three continents. It uniquely invests in high-potential individuals, helping them find co-founders, develop ideas, and secure funding to build globally significant technology companies. With a portfolio of over 300 companies, including notable successes like Tractable and Magic Pony Technology, and a global alumni network of over 5000, Entrepreneur First has a combined portfolio value of over $5 billion. Backed by prominent tech founders and investors, the firm focuses on the software and technology sectors.

Sam Barnett

President

Clémence Bellanger

Principal, Paris

Jonny Clifford

Partner and General Partner, London

Philipp Herkelmann

Partner and General Manager

Elspeth Lawson

Partner and Deputy CPO

Chris Mairs

Venture Partner

Rahul Samat

Partner and General Manager, Banglore

Tom Shinner

Partner and COO

Oliver Walerys

Founder

Past deals in Nanotechnology

Level Zero

Pre Seed Round in 2025
Level Zero Health is a technology company specializing in advanced biosensor solutions. It develops wearable devices equipped with DNA-based sensors, designed to precisely monitor key endocrine biomarkers in real-time. By combining biochemistry and nanotechnology, the company collects novel data, empowering users to gain insights into their hormonal health.

Level Zero

Seed Round in 2024
Level Zero Health is a technology company specializing in advanced biosensor solutions. It develops wearable devices equipped with DNA-based sensors, designed to precisely monitor key endocrine biomarkers in real-time. By combining biochemistry and nanotechnology, the company collects novel data, empowering users to gain insights into their hormonal health.

Allozymes

Series A in 2023
Allozymes is a prominent deep technology company that specializes in the application of ultrahigh-throughput microfluidics technology to enhance the evolution and development of enzymes. The company focuses on creating sensitive and accurate assays for enzymatic reactions, utilizing proprietary microfluidic chips and proteomics technologies. Allozymes' platform integrates molecular biology and process engineering to produce high-purity enzymes tailored for specific applications. This innovative approach enables clients to expedite custom enzyme development and to create novel, sustainable natural products, positioning Allozymes as a leader in the enzyme development sector.

SunGreenH2

Seed Round in 2022
SunGreenH2 is a company focused on producing high-performance electrolysers for green hydrogen generation using advanced materials and nanotechnology. Founded in 2020 and headquartered in Singapore, with additional offices in Melbourne and London, the company has developed a modular and scalable electrolyser stack that enables on-site hydrogen production at a low cost. By utilizing sunlight and water, SunGreenH2's patented technology facilitates the production of zero-emissions hydrogen, supporting sustainable practices across various industries, including transport, buildings, and specialty chemicals. With over a decade of research in electrochemistry and nanotechnology, SunGreenH2 aims to enable widespread adoption of green hydrogen, contributing to a more sustainable energy landscape.

Allozymes

Seed Round in 2021
Allozymes is a prominent deep technology company that specializes in the application of ultrahigh-throughput microfluidics technology to enhance the evolution and development of enzymes. The company focuses on creating sensitive and accurate assays for enzymatic reactions, utilizing proprietary microfluidic chips and proteomics technologies. Allozymes' platform integrates molecular biology and process engineering to produce high-purity enzymes tailored for specific applications. This innovative approach enables clients to expedite custom enzyme development and to create novel, sustainable natural products, positioning Allozymes as a leader in the enzyme development sector.

Nanofy

Pre Seed Round in 2020
Nanofy Technologies was an industrial solutions developer specializing in nano-materials, founded during the COVID-19 pandemic as part of Entrepreneur First's 8th Singapore cohort. The company focused on creating a self-disinfection coating designed to eliminate microbes upon contact by harnessing visible light to generate photocatalytic reactions. This innovative technology aimed to reduce the spread of pathogens in high-traffic indoor environments. After a year of research and development, Nanofy struggled to compete with established technologies in ISO-certified trials, leading to its closure in September 2021 due to an inability to progress beyond pilot implementations.

BioFeyn

Seed Round in 2020
BioFeyn is a company focused on enhancing the diet of farmed fish to boost health and sustainability in aquaculture. By optimizing marine ingredients, BioFeyn enables fish to receive nutrients akin to those found in their natural ocean habitat, resulting in improved efficiency across the industry. The company employs a specialized method of biodegradable nanoencapsulation, which surrounds trace amounts of marine ingredients with a shell of naturally-derived compounds. This innovative approach enhances digestion, absorption, and the bioavailability of nutrients, ensuring effective delivery to target tissues in the fish. Ultimately, BioFeyn's solutions aim to produce healthier fish while minimizing environmental impact, making the practice of consuming farmed fish more sustainable and nutritious for consumers.

Allozymes

Seed Round in 2020
Allozymes is a prominent deep technology company that specializes in the application of ultrahigh-throughput microfluidics technology to enhance the evolution and development of enzymes. The company focuses on creating sensitive and accurate assays for enzymatic reactions, utilizing proprietary microfluidic chips and proteomics technologies. Allozymes' platform integrates molecular biology and process engineering to produce high-purity enzymes tailored for specific applications. This innovative approach enables clients to expedite custom enzyme development and to create novel, sustainable natural products, positioning Allozymes as a leader in the enzyme development sector.

Seppure Technologies

Seed Round in 2019
Seppure Technologies is focused on transforming the energy-intensive processes of chemical separation and purification utilized across various industries. The company has developed innovative chemical-resistant nanofiltration membranes that replace traditional methods such as distillation and evaporation. By implementing this sustainable technology, Seppure enables clients to significantly reduce their energy consumption, emissions, and pollution. This approach not only enhances the efficiency of industrial-scale chemical separations but also contributes to a more environmentally friendly manufacturing landscape.

FabricNano

Seed Round in 2019
FabricNano Limited, founded in 2018 and headquartered in London, United Kingdom, specializes in cell-free biomanufacturing, focusing on the development of innovative biocatalysts and artificial cells. The company leverages advancements in nanotechnology and biotechnology to create designs and construction schematics for artificial cells that enhance the speed, purity, and adaptability of chemical reactions. By optimizing these processes, FabricNano enables businesses to streamline production workflows, eliminate capacity bottlenecks, and reduce associated costs, thereby unlocking new possibilities in the realm of biochemistry.

ShapeNine

Pre Seed Round in 2019
ShapeNine Ltd is a London-based company established in 2019 that specializes in the development of software for designing deoxyribonucleic acid (DNA) structures. Utilizing artificial intelligence and advanced algorithms, ShapeNine creates low-cost biomolecules for one-step purification of proteins and biologicals. The company's innovative platform leverages DNA as an engineering material, allowing for the precise control of industrial applications at the nanoscale. This technology is particularly beneficial for the biochemical, electronic, and pharmaceutical industries, enabling customers to implement functional designs tailored for specific tasks.

Seppure Technologies

Pre Seed Round in 2018
Seppure Technologies is focused on transforming the energy-intensive processes of chemical separation and purification utilized across various industries. The company has developed innovative chemical-resistant nanofiltration membranes that replace traditional methods such as distillation and evaporation. By implementing this sustainable technology, Seppure enables clients to significantly reduce their energy consumption, emissions, and pollution. This approach not only enhances the efficiency of industrial-scale chemical separations but also contributes to a more environmentally friendly manufacturing landscape.
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