Oxford Science Enterprises

Oxford Science Enterprises is a venture capital firm based in Oxford, United Kingdom, specializing in seed and Series A investments. Established in 2015, the firm focuses on spin-outs from the University of Oxford, targeting sectors such as life sciences, healthcare, biotechnology, cleantech, and advanced technology. Oxford Science Enterprises aims to build science-based businesses that address significant global challenges, including nuclear fusion, quantum computing, and the development of treatments for infectious diseases. The firm has raised over £600 million to foster a robust technology ecosystem, leveraging its extensive network of investors, entrepreneurs, and industry experts to support co-investment, business development, and talent acquisition.

Matthew Arnold

Principal

Lilly Bussmann

Investor

Sally Dewhurst

Principal, Life Sciences

Nick Dixon-Clegg

Principal

William Goodlad

Principal

Sam Harman

Principal and Acting Head of Deep Tech

James Wong

Principal

Katya Smirnyagina Ph.D

Senior Partner, Life Sciences

Liliane Chamas Ph.D

Principal, Health Tech

Oliver Mahony Ph.D

Principal

Past deals in Nanotechnology

Oxford Quantum Circuits

Series A in 2022
Oxford Quantum Circuits developing technology using the power of quantum to do things which have never been achieved before, from enabling life-changing drug discoveries to developing new battery technologies.

Salience Labs

Seed Round in 2022
Salience Labs is building a hybrid photonic-electronic chip for AI. We have designed a massively parallel, ultra-high-throughput Photonic Tensor Processing Unit. Photonics allows data to be modulated at up to 100 GHZ, and allows for high levels of parallelization using multiplexing. We integrate this photonic unit into a SoC architecture designed to exploit its high throughput for AI inference. Salience Labs technology is based on decades of research collaboration between Oxford University and the University of Münster, Germany.

ONI

Series B in 2021
Oxford NanoImaging Limited specializes in the development and manufacture of advanced microscopy tools for life sciences research. The company's flagship product, the Nanoimager, is a single-molecule fluorescence microscope designed to detect biomolecules, including disease-related protein markers and pathogens, at single copy numbers. This innovative microscope features capabilities such as 3D imaging and dual-color super-resolution, enhancing researchers' ability to study complex biological processes. In addition to the Nanoimager, Oxford NanoImaging offers various microscopy technologies, including Förster Resonance Energy Transfer microscopy, direct stochastic optical reconstruction microscopy, and photoactivated localization microscopy. Founded in 2016 and headquartered in London, with an additional office in Menlo Park, California, the company aims to make life science tools and knowledge accessible to a wider audience.

Alethiomics

Seed Round in 2021
Alethiomics is a pre-clinical biotech company focused on developing targeted therapies for blood cancers. Utilizing advanced single-cell multi-omic technology, the company aims to discover and create innovative treatments for myeloproliferative neoplasms, which originate from mutations in cancer stem cells within the bone marrow. By leveraging this cutting-edge approach, Alethiomics seeks to provide medical professionals with effective and potentially curative therapies for patients suffering from these conditions.

Navenio

Venture Round in 2021
Navenio is a software technology company that provides location-based services for indoor environments via mobile applications. Its solution provides an improvement on other indoor localization technologies, having the ability to locate people without the need for implementing, managing, or surveying any new building hardware such as beacons or wi-fi. Navenio’s intelligent workforce solution unlocks significant improvements in the efficiency and workflow of staff and teams through automation that is carefully driven from real-world best practice. The company was founded in 2015 and is headquartered in Oxford, England.

Oxford Endovascular

Series A in 2021
Oxford Endovascular are developing a novel treatment for treating brain aneurysms. The Oxford technology uses a special laser-cut metal alloy which has a shape-memory. It can be posted into a catheter during surgery, inserted into the brain and opened up into a tiny tube mesh (‘flow diverter’) that fits into the natural shape of the blood vessel. This diverts the blood away from the aneurysm, allowing it to heal.

SpyBiotech

Series A in 2021
SpyBiotech Limited, founded in 2017 and based in Oxford, United Kingdom, specializes in the development of innovative vaccines through its proprietary biotechnology platform. The company utilizes a unique molecular superglue to bond antigens to viruses and other particles, facilitating the rapid creation of vaccines aimed at a variety of diseases. This advanced technology enables medical institutions and research centers to produce next-generation vaccines that demonstrate improved efficacy and reduced development time, thereby enhancing the overall vaccine development process.

Theolytics

Series A in 2021
Theolytics is a pre-clinical stage biotechnology company developing next-generation oncolytic viral therapies. The company was formed in 2017 to drive the development of a pipeline of novel clinical trial candidates, and is led by a team that combines over 40 years of experience in oncolytic virus development. The company uses an adenovirus platform to develop targeted, self-amplifying therapeutic agents, and aims to deliver innovative cancer care to millions of people in need worldwide.

Refeyn

Series A in 2020
Refeyn specializes in label-free single molecule imaging and mass measurement, offering advanced microscopy solutions for detecting and quantifying molecules. Their technology enables users to perform precise imaging, localization, and accurate mass determination of individual biomolecules in solution. This innovative approach serves various sectors, particularly pharmaceutical, biomedical, and research industries. Founded in 2018 and headquartered in Oxford, United Kingdom, Refeyn aims to enhance research capabilities by providing tools that facilitate a deeper understanding of molecular interactions and properties.

Oxford Ionics

Seed Round in 2020
Developer of advanced quantum computing systems designed to create chips for high-performance applications. The company's platform features trapped-ion technology that enables scalability and efficiency, utilizing standard semiconductor fabrication methods to produce quantum chips globally, enabling clients to facilitate significant advancements in the quantum computing market and providing enhanced computational capabilities for complex problem-solving.

Navenio

Series A in 2020
Navenio is a software technology company that provides location-based services for indoor environments via mobile applications. Its solution provides an improvement on other indoor localization technologies, having the ability to locate people without the need for implementing, managing, or surveying any new building hardware such as beacons or wi-fi. Navenio’s intelligent workforce solution unlocks significant improvements in the efficiency and workflow of staff and teams through automation that is carefully driven from real-world best practice. The company was founded in 2015 and is headquartered in Oxford, England.

Quantum Motion

Series A in 2020
Quantum Motion Technologies Limited is focused on developing a universal quantum computer utilizing silicon-based technology and CMOS-compatible processes. Founded in 2017 and based in Leeds, United Kingdom, the company aims to create scalable quantum computing architectures that address issues such as fault tolerance and qubit redundancy. Its technology is designed to enhance qubit density, allowing for the construction of large-scale quantum systems capable of solving complex problems in various fields, including chemistry, medicine, and artificial intelligence. By leveraging advanced architectural approaches, Quantum Motion Technologies seeks to advance the quantum technology sector and provide solutions that reduce errors and overcome critical challenges in quantum information processing.

ONI

Series A in 2018
Oxford NanoImaging Limited specializes in the development and manufacture of advanced microscopy tools for life sciences research. The company's flagship product, the Nanoimager, is a single-molecule fluorescence microscope designed to detect biomolecules, including disease-related protein markers and pathogens, at single copy numbers. This innovative microscope features capabilities such as 3D imaging and dual-color super-resolution, enhancing researchers' ability to study complex biological processes. In addition to the Nanoimager, Oxford NanoImaging offers various microscopy technologies, including Förster Resonance Energy Transfer microscopy, direct stochastic optical reconstruction microscopy, and photoactivated localization microscopy. Founded in 2016 and headquartered in London, with an additional office in Menlo Park, California, the company aims to make life science tools and knowledge accessible to a wider audience.

Metaboards

Series A in 2018
Metaboards is a pioneer in the field of metamaterials, specializing in the development of innovative solutions for wireless charging. The company focuses on creating materials that possess unique properties not found in nature, allowing for the wireless powering of multiple electronic devices across large surfaces. Their technology enables devices to be charged without the need for precise alignment or multiple power inputs, eliminating vulnerabilities associated with traditional connectors. By exploring the potential of metamaterials, Metaboards aims to transform the functionality of wireless charging, providing flexible and efficient solutions for both businesses and individuals.

Xerion Healthcare

Venture Round in 2018
Xerion Healthcare Limited is a UK-based company focused on developing and commercializing nanoparticle treatments to enhance the effectiveness of cancer therapies, specifically targeting head, neck, and pancreatic tumors. Founded in 2015, the company utilizes titanium dioxide nanoparticles, a non-toxic semiconductor material, which are injected into tumors prior to standard radiotherapy. This innovative approach amplifies the dose of free radicals produced by X-rays, thereby improving the treatment's efficacy while minimizing potential side effects. By integrating this nanomedicine technology into conventional radiotherapy, Xerion Healthcare aims to provide more effective solutions for patients with challenging cancer types.

Navenio

Seed Round in 2017
Navenio is a software technology company that provides location-based services for indoor environments via mobile applications. Its solution provides an improvement on other indoor localization technologies, having the ability to locate people without the need for implementing, managing, or surveying any new building hardware such as beacons or wi-fi. Navenio’s intelligent workforce solution unlocks significant improvements in the efficiency and workflow of staff and teams through automation that is carefully driven from real-world best practice. The company was founded in 2015 and is headquartered in Oxford, England.

Theolytics

Seed Round in 2017
Theolytics is a pre-clinical stage biotechnology company developing next-generation oncolytic viral therapies. The company was formed in 2017 to drive the development of a pipeline of novel clinical trial candidates, and is led by a team that combines over 40 years of experience in oncolytic virus development. The company uses an adenovirus platform to develop targeted, self-amplifying therapeutic agents, and aims to deliver innovative cancer care to millions of people in need worldwide.

Quantum Motion

Seed Round in 2017
Quantum Motion Technologies Limited is focused on developing a universal quantum computer utilizing silicon-based technology and CMOS-compatible processes. Founded in 2017 and based in Leeds, United Kingdom, the company aims to create scalable quantum computing architectures that address issues such as fault tolerance and qubit redundancy. Its technology is designed to enhance qubit density, allowing for the construction of large-scale quantum systems capable of solving complex problems in various fields, including chemistry, medicine, and artificial intelligence. By leveraging advanced architectural approaches, Quantum Motion Technologies seeks to advance the quantum technology sector and provide solutions that reduce errors and overcome critical challenges in quantum information processing.

Oxford Quantum Circuits

Series A in 2017
Oxford Quantum Circuits developing technology using the power of quantum to do things which have never been achieved before, from enabling life-changing drug discoveries to developing new battery technologies.

ONI

Seed Round in 2017
Oxford NanoImaging Limited specializes in the development and manufacture of advanced microscopy tools for life sciences research. The company's flagship product, the Nanoimager, is a single-molecule fluorescence microscope designed to detect biomolecules, including disease-related protein markers and pathogens, at single copy numbers. This innovative microscope features capabilities such as 3D imaging and dual-color super-resolution, enhancing researchers' ability to study complex biological processes. In addition to the Nanoimager, Oxford NanoImaging offers various microscopy technologies, including Förster Resonance Energy Transfer microscopy, direct stochastic optical reconstruction microscopy, and photoactivated localization microscopy. Founded in 2016 and headquartered in London, with an additional office in Menlo Park, California, the company aims to make life science tools and knowledge accessible to a wider audience.

SpyBiotech

Seed Round in 2017
SpyBiotech Limited, founded in 2017 and based in Oxford, United Kingdom, specializes in the development of innovative vaccines through its proprietary biotechnology platform. The company utilizes a unique molecular superglue to bond antigens to viruses and other particles, facilitating the rapid creation of vaccines aimed at a variety of diseases. This advanced technology enables medical institutions and research centers to produce next-generation vaccines that demonstrate improved efficacy and reduced development time, thereby enhancing the overall vaccine development process.

Argonaut Therapeutics

Seed Round in 2016
Argonaut Therapeutics Limited, founded in 2016 and based in Oxford, United Kingdom, specializes in developing epigenetically acting drugs for cancer treatment. The company focuses on targeting abnormal arginine methylation, a modification linked to cancer progression, by utilizing pioneering research from the University of Oxford. Argonaut aims to create precision cancer medicines that reprogram cancer cells to trigger the body's natural cell death processes. This innovative approach seeks to provide advanced treatment options that may enhance patient recovery and improve outcomes in cancer therapy.

iotaSciences

Seed Round in 2016
Iota Sciences Ltd. engages in developing and delivering tools and technologies based on fluid shaping technologies to accelerate drug discovery. It develops fluidic mu-wells for cell biology. The company was founded in 2016 and is headquartered in Oxford, United Kingdom.

ONI

Seed Round in 2016
Oxford NanoImaging Limited specializes in the development and manufacture of advanced microscopy tools for life sciences research. The company's flagship product, the Nanoimager, is a single-molecule fluorescence microscope designed to detect biomolecules, including disease-related protein markers and pathogens, at single copy numbers. This innovative microscope features capabilities such as 3D imaging and dual-color super-resolution, enhancing researchers' ability to study complex biological processes. In addition to the Nanoimager, Oxford NanoImaging offers various microscopy technologies, including Förster Resonance Energy Transfer microscopy, direct stochastic optical reconstruction microscopy, and photoactivated localization microscopy. Founded in 2016 and headquartered in London, with an additional office in Menlo Park, California, the company aims to make life science tools and knowledge accessible to a wider audience.

Navenio

Seed Round in 2016
Navenio is a software technology company that provides location-based services for indoor environments via mobile applications. Its solution provides an improvement on other indoor localization technologies, having the ability to locate people without the need for implementing, managing, or surveying any new building hardware such as beacons or wi-fi. Navenio’s intelligent workforce solution unlocks significant improvements in the efficiency and workflow of staff and teams through automation that is carefully driven from real-world best practice. The company was founded in 2015 and is headquartered in Oxford, England.

Sonosine

Seed Round in 2015
Sonosine, operating under the name Oxford Enhanced Medical Limited, specializes in the development of advanced imaging technology that enhances diagnostic capabilities in the medical field. Founded in 2015 and based in Begbroke, United Kingdom, the company focuses on delivering diagnostic electromagnetic imaging solutions that enable the detection of cancers, particularly prostate and liver tumors. This innovative technology aims to provide high-quality imaging and tissue characterization at a lower cost, making advanced diagnostic resources accessible to a broader community than currently available. The company's origins trace back to research at the University of Oxford, positioning it at the forefront of medical imaging advancements.
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