Novartis

Novartis is a global healthcare company based in Switzerland, providing innovative medicines and solutions to address evolving patient needs worldwide. With over 100,000 employees across 140 countries, they focus on discovering new treatments in areas such as oncology, immunology, neuroscience, and cardiovascular diseases.

Elena Battistello

Analyst

Laura Brass

Managing Director

Adam Cotton

Associate

Bart Dzikowski

Managing Director

Mathias Frederiksen

Principal

Sharon Kiernan

Director of Strategic Planning and Business Operations, Office of Chief Technology Transformation Officer

Anja Konig

Managing Director

Michelle Ma

Analyst

Nadene McIntyre

Associate Director Access and Reimbursement

Campbell Murray MD

Managing Director

Marion Mutter

Senior Clinical Research Associate

Florian Müllershausen

Managing Director

Aaron Nelson

Managing Director

Pascal Qian

Executive Director ( Head of Solid Tumor)

Michal Silverberg

Managing Director

Lauren Silverman

Managing Director

Beat Steffen

Managing Director

Marianne Uteng

Managing Director

Alberto Villena

Director, M&A, Finance

Maurizio Voi

Vice President, Global Program Head, Tislelizumab, Immuno Oncology

Steve Weinstein

Managing Director

Past deals in Health Care

Granite Bio

Series A in 2025
Granite Bio is a biotechnology company focused on developing novel monoclonal antibody therapies targeting inflammatory, autoimmune, and fibrotic disorders.

Anthos Therapeutics

Acquisition in 2025
Anthos Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, focused on advancing therapies for cardiovascular and metabolic diseases. Founded in 2018, the company specializes in developing innovative treatments that target Factor XI and XIa, critical components of the intrinsic coagulation pathway. Its lead product, MAA868, is an anti-thrombotic investigational therapy designed to prevent thrombotic events while minimizing the risk of bleeding. By offering a long-acting treatment paradigm, Anthos Therapeutics aims to provide significant advantages over conventional standards of care, ultimately enhancing patient outcomes in cardiovascular health.

Mariana Oncology

Acquisition in 2024
Mariana Oncology is a biotechnology company focused on developing innovative radiopharmaceuticals aimed at targeting cancer cells with radioactive drugs. The company employs a multidisciplinary approach that includes ligand discovery, radiochemistry, radiobiology, and translational and clinical research in oncology. By building a diverse pipeline of treatments for various solid tumor types, Mariana Oncology seeks to enhance the efficacy of radio medicines in cancer therapy, ultimately aiding medical professionals in their efforts to improve patient outcomes.

Enterprise Therapeutics

Series B in 2024
Enterprise Therapeutics is a United Kingdom-based drug discovery company founded in 2014 and based in Brighton. It develops novel disease-modifying therapies for respiratory diseases, including cystic fibrosis, asthma, and COPD, with a focus on addressing the underlying mechanisms of mucus congestion to improve breathing, reduce lung infections, and enhance patient quality of life.

Octave

Series B in 2023
Octave is a clinical platform developer focused on transforming the care landscape for multiple sclerosis and other neurodegenerative diseases. The company creates a platform that generates, analyzes, and integrates data to improve patient outcomes and reduce overall healthcare costs. By optimizing medication usage and healthcare services, Octave aims to enhance the efficiency of the pharmaceutical industry throughout the entire lifecycle of drug development, which includes discovery, clinical trials, and post-marketing phases. Their approach utilizes real-world evidence to inform decision-making, ultimately striving to set a new standard in multiple sclerosis care.

Patientory

Venture Round in 2023
Patientory is a digital health data platform that enables individuals to store and manage personal medical records and health information, empowering patients to control their data. The platform securely manages records, offers AI-driven health coaching, tracks wellness metrics, connects users to clinical trials and affordable medications, and rewards healthy behaviors. It facilitates connections between patients and healthcare providers to support care coordination. Founded in 2015 and based in Atlanta, the company aims to streamline access to health information and enable patients to benefit from their data.

Aktis Oncology

Series A in 2022
Aktis Oncology is a biotechnology company developing targeted radiopharmaceuticals for treating various solid tumor cancers. Its proprietary platforms generate tumor-targeting agents with optimal properties for alpha radiotherapy, ensuring high tumor penetration and long residence time to maximize tumor elimination while minimizing side effects.

Klarah

Grant in 2022
Klarah is a digital health company specializing in telehealth solutions. It operates a platform that connects patients with a network of specialist doctors and nurses, providing remote medical consultations, support, and monitoring. The company's services include wound care, wellness checks, post-hospital care, and diabetes management. Klarah's platform also offers a dashboard for accessing medical history and real-time updates on key health parameters. Notably, Klarah focuses on serving the African diaspora by providing quality healthcare to their loved ones on the continent.

GentiBio

Series A in 2021
GentiBio, Inc. is a biotherapeutics company that specializes in developing engineered regulatory T cells, known as EngTregs, aimed at treating autoimmune, alloimmune, autoinflammatory, and allergic diseases. Founded in 2020 and headquartered in Boston, Massachusetts, with additional locations in Israel and Seattle, Washington, GentiBio employs a proprietary platform that combines autologous and allogeneic technologies. This platform enhances the ability to restore immune tolerance and addresses significant limitations found in existing regulatory T-cell therapeutics. By focusing on the underlying mechanisms of immune system disorders, GentiBio aims to provide innovative therapeutic solutions that tackle the root causes of diseases caused by dysregulated immune responses. The company is co-founded by experts in Treg biology and synthetic immunology, positioning it at the forefront of advanced immunotherapy development.

Aktis Oncology

Series A in 2021
Aktis Oncology is a biotechnology company developing targeted radiopharmaceuticals for treating various solid tumor cancers. Its proprietary platforms generate tumor-targeting agents with optimal properties for alpha radiotherapy, ensuring high tumor penetration and long residence time to maximize tumor elimination while minimizing side effects.

Aspen RxHealth

Series B in 2021
Aspen RxHealth is a Tampa, Florida-based company that provides an online platform designed to connect licensed pharmacists with patients requiring enhanced medication services. Through its app-based technology, Aspen RxHealth facilitates direct patient care by matching pharmacists with patients based on various social and clinical criteria, including language and medication regimens. The platform enables health plans and providers to efficiently link their patients to a community of pharmacists who can offer specialized clinical services, ranging from comprehensive medication reviews to targeted interventions. By optimizing communication and simplifying processes, Aspen RxHealth aims to improve patient outcomes and enhance the delivery of pharmaceutical care.

Science 37

Venture Round in 2020
Science 37 specializes in decentralized clinical trials, offering a technology-driven approach that enables patients to participate from their homes. The company's platform connects researchers with patients via telemedicine investigators and mobile nurses, accelerating trial enrollment and retention while reaching a more diverse patient population.

GentiBio

Seed Round in 2020
GentiBio, Inc. is a biotherapeutics company that specializes in developing engineered regulatory T cells, known as EngTregs, aimed at treating autoimmune, alloimmune, autoinflammatory, and allergic diseases. Founded in 2020 and headquartered in Boston, Massachusetts, with additional locations in Israel and Seattle, Washington, GentiBio employs a proprietary platform that combines autologous and allogeneic technologies. This platform enhances the ability to restore immune tolerance and addresses significant limitations found in existing regulatory T-cell therapeutics. By focusing on the underlying mechanisms of immune system disorders, GentiBio aims to provide innovative therapeutic solutions that tackle the root causes of diseases caused by dysregulated immune responses. The company is co-founded by experts in Treg biology and synthetic immunology, positioning it at the forefront of advanced immunotherapy development.

Poseida Therapeutics

Series C in 2019
Poseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, dedicated to developing innovative therapeutics for patients with significant unmet medical needs. The company specializes in genome engineering technologies and is focused on creating targeted treatments, including a pipeline of autologous and allogeneic chimeric antigen receptor T cell (CAR-T) therapies aimed at addressing hematological malignancies and solid tumors. Additionally, Poseida is advancing gene therapies for rare and life-threatening diseases, such as Ornithine transcarbamylase deficiency and methylmalonic acidemia, along with therapies for genetic liver diseases. Founded in 2014, Poseida Therapeutics is committed to improving patient outcomes through its cutting-edge research and development efforts.

Anthos Therapeutics

Series A in 2019
Anthos Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, focused on advancing therapies for cardiovascular and metabolic diseases. Founded in 2018, the company specializes in developing innovative treatments that target Factor XI and XIa, critical components of the intrinsic coagulation pathway. Its lead product, MAA868, is an anti-thrombotic investigational therapy designed to prevent thrombotic events while minimizing the risk of bleeding. By offering a long-acting treatment paradigm, Anthos Therapeutics aims to provide significant advantages over conventional standards of care, ultimately enhancing patient outcomes in cardiovascular health.

Enterprise Therapeutics

Series B in 2018
Enterprise Therapeutics is a United Kingdom-based drug discovery company founded in 2014 and based in Brighton. It develops novel disease-modifying therapies for respiratory diseases, including cystic fibrosis, asthma, and COPD, with a focus on addressing the underlying mechanisms of mucus congestion to improve breathing, reduce lung infections, and enhance patient quality of life.

Effector Therapeutics

Series C in 2017
eFFECTOR Therapeutics, Inc. is a clinical-stage biotechnology company based in San Diego, California, that specializes in the development of selective translation regulators for the treatment of cancer and other serious diseases. Founded in 2012, the company is pioneering a new class of oncology drugs known as selective translation regulator inhibitors (STRIs). These drug candidates specifically target the eIF4F complex and its associated kinase, MNK 1/2, which play critical roles in protein synthesis and are linked to prominent cancer signaling pathways such as PI3K-AKT and RAS-MEK. eFFECTOR's products aim to inhibit pathways that drive tumor growth, survival, and immune evasion by regulating the expression of oncoproteins and immunosuppressive proteins. The lead candidate, tomivosertib, is currently being evaluated in a Phase 2b trial for non-small cell lung cancer in combination with pembrolizumab. Additionally, zotatifin, an inhibitor of eIF4A, is undergoing dose-escalation in a Phase 1/2 trial, with further expansion cohorts anticipated. The company also collaborates with Pfizer to advance inhibitors targeting eIF4E.

Gamida Cell

Series F in 2017
Gamida Cell Ltd., established in 1998 and headquartered in Jerusalem, Israel, is a clinical-stage biopharmaceutical company focused on developing advanced cell therapies to treat blood cancers and serious blood diseases. The company's lead product candidate, omidubicel, is an expanded hematopoietic stem cell therapy derived from umbilical cord blood, currently in Phase 3 studies for patients with high-risk hematologic malignancies and severe aplastic anemia. Additionally, Gamida Cell is developing GDA-201, a natural killer cell-based cancer immunotherapy, which is in Phase 1/2 trials for relapsed or refractory non-Hodgkin lymphoma and multiple myeloma. Both candidates leverage the company's proprietary expansion platform based on nicotinamide to enhance cell properties and therapeutic potential.

Lemonaid Health

Series A in 2017
Founded in 2013, Lemonaid Health specializes in improving patient experience through advanced machine learning and AI. It offers direct-to-consumer telemedicine services, utilizing evidence-based guidelines to provide affordable healthcare.

Aerpio Pharmaceuticals

Venture Round in 2017
Aerpio Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company based in Cincinnati, Ohio, focused on developing innovative compounds for the treatment of ocular diseases and diabetic complications. The company's lead candidate, razuprotafib, is a small molecule activator of the Tie2 pathway that has completed a Phase IIb clinical trial for diabetic retinopathy. Additionally, Aerpio is advancing ARP-1536, a humanized monoclonal antibody in preclinical development for diabetic vascular complications, and GB004, a selective stabilizer of hypoxia-inducible factor-1 alpha, currently undergoing a Phase 1b trial for inflammatory bowel disease. Furthermore, the company is developing a bispecific antibody for the treatment of wet age-related macular degeneration and diabetic macular edema. Aerpio has also partnered with Quantum Leap Healthcare Collaborative to evaluate razuprotafib's potential in treating acute respiratory distress syndrome in COVID-19 patients. Founded in 2011, Aerpio Pharmaceuticals aims for rapid development of its promising therapies.

Inflazome

Series A in 2016
Inflazome Ltd. is a biotechnology company based in Dublin, Ireland, established in 2016. The company specializes in developing orally available drugs aimed at addressing unmet clinical needs in inflammatory diseases by targeting inflammasomes, which are critical in the inflammatory process. Inflazome's innovative therapies are designed to block inflammasome signals, thereby addressing the root causes of inflammation. The company's portfolio includes treatments for a range of conditions, such as neurological disorders like Alzheimer's and Parkinson's, systemic inflammatory diseases, and certain orphan diseases. As of September 2020, Inflazome operates as a subsidiary of Roche Holding AG, further enhancing its capacity to deliver targeted therapies in the field of inflammatory diseases.

COTA Healthcare

Series B in 2016
COTA, Inc. is a Boston-based company that specializes in developing a platform designed to provide data and insights related to cancer patients, aimed at guiding treatment decisions. Founded in 2011 by a team of doctors, engineers, and data scientists, COTA utilizes proprietary technology and advanced analytics to transform fragmented electronic health record (EHR) data into cohesive, research-grade information. This platform supports oncology practices and cancer centers by identifying variations in care, thus enabling the design of effective treatment programs and payment models. COTA's solutions serve a diverse range of stakeholders, including healthcare providers, payers, life sciences companies, and the FDA, ultimately striving to enhance patient outcomes and reduce healthcare costs associated with cancer care.

Effector Therapeutics

Series B in 2015
eFFECTOR Therapeutics, Inc. is a clinical-stage biotechnology company based in San Diego, California, that specializes in the development of selective translation regulators for the treatment of cancer and other serious diseases. Founded in 2012, the company is pioneering a new class of oncology drugs known as selective translation regulator inhibitors (STRIs). These drug candidates specifically target the eIF4F complex and its associated kinase, MNK 1/2, which play critical roles in protein synthesis and are linked to prominent cancer signaling pathways such as PI3K-AKT and RAS-MEK. eFFECTOR's products aim to inhibit pathways that drive tumor growth, survival, and immune evasion by regulating the expression of oncoproteins and immunosuppressive proteins. The lead candidate, tomivosertib, is currently being evaluated in a Phase 2b trial for non-small cell lung cancer in combination with pembrolizumab. Additionally, zotatifin, an inhibitor of eIF4A, is undergoing dose-escalation in a Phase 1/2 trial, with further expansion cohorts anticipated. The company also collaborates with Pfizer to advance inhibitors targeting eIF4E.

Aerpio Pharmaceuticals

Series C in 2014
Aerpio Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company based in Cincinnati, Ohio, focused on developing innovative compounds for the treatment of ocular diseases and diabetic complications. The company's lead candidate, razuprotafib, is a small molecule activator of the Tie2 pathway that has completed a Phase IIb clinical trial for diabetic retinopathy. Additionally, Aerpio is advancing ARP-1536, a humanized monoclonal antibody in preclinical development for diabetic vascular complications, and GB004, a selective stabilizer of hypoxia-inducible factor-1 alpha, currently undergoing a Phase 1b trial for inflammatory bowel disease. Furthermore, the company is developing a bispecific antibody for the treatment of wet age-related macular degeneration and diabetic macular edema. Aerpio has also partnered with Quantum Leap Healthcare Collaborative to evaluate razuprotafib's potential in treating acute respiratory distress syndrome in COVID-19 patients. Founded in 2011, Aerpio Pharmaceuticals aims for rapid development of its promising therapies.

Alios BioPharma

Series B in 2014
Alios BioPharma is focused on discovering and developing innovative antiviral therapies aimed at treating both acute and chronic viral infections. The company utilizes a range of proprietary platform technologies, including small molecule activators of innate immunity, phosphate-protected nucleotide prodrug chemistry, and glycoprotein-engineering of interferons. These technologies enable the development of distinct therapeutic products targeting serious viral conditions such as chronic hepatitis B and C, HIV, and respiratory viruses, including pandemic influenza and emerging diseases like SARS. Alios BioPharma's approach is supported by a proprietary chemical library of nucleoside analogs and advanced virology-based screening systems, positioning the company as a key player in the field of antiviral therapeutics.

Aerpio Pharmaceuticals

Series A in 2013
Aerpio Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company based in Cincinnati, Ohio, focused on developing innovative compounds for the treatment of ocular diseases and diabetic complications. The company's lead candidate, razuprotafib, is a small molecule activator of the Tie2 pathway that has completed a Phase IIb clinical trial for diabetic retinopathy. Additionally, Aerpio is advancing ARP-1536, a humanized monoclonal antibody in preclinical development for diabetic vascular complications, and GB004, a selective stabilizer of hypoxia-inducible factor-1 alpha, currently undergoing a Phase 1b trial for inflammatory bowel disease. Furthermore, the company is developing a bispecific antibody for the treatment of wet age-related macular degeneration and diabetic macular edema. Aerpio has also partnered with Quantum Leap Healthcare Collaborative to evaluate razuprotafib's potential in treating acute respiratory distress syndrome in COVID-19 patients. Founded in 2011, Aerpio Pharmaceuticals aims for rapid development of its promising therapies.

Opsona Therapeutics

Series C in 2013
Opsona Therapeutics is a Dublin-based drug development company specializing in immunology, particularly the modulation of innate immunity pathways. Founded in 2004, the company has developed innovative therapeutic approaches aimed at treating autoimmune and inflammatory diseases, as well as cancer. By targeting the innate immune system, Opsona addresses a spectrum of significant health challenges, including transplant rejection, diabetes, Alzheimer's disease, and atherosclerosis. The company seeks to improve patient outcomes through its novel drug candidates and strategies, positioning itself as a leader in emerging immunology research and drug development in Europe.

Effector Therapeutics

Series A in 2013
eFFECTOR Therapeutics, Inc. is a clinical-stage biotechnology company based in San Diego, California, that specializes in the development of selective translation regulators for the treatment of cancer and other serious diseases. Founded in 2012, the company is pioneering a new class of oncology drugs known as selective translation regulator inhibitors (STRIs). These drug candidates specifically target the eIF4F complex and its associated kinase, MNK 1/2, which play critical roles in protein synthesis and are linked to prominent cancer signaling pathways such as PI3K-AKT and RAS-MEK. eFFECTOR's products aim to inhibit pathways that drive tumor growth, survival, and immune evasion by regulating the expression of oncoproteins and immunosuppressive proteins. The lead candidate, tomivosertib, is currently being evaluated in a Phase 2b trial for non-small cell lung cancer in combination with pembrolizumab. Additionally, zotatifin, an inhibitor of eIF4A, is undergoing dose-escalation in a Phase 1/2 trial, with further expansion cohorts anticipated. The company also collaborates with Pfizer to advance inhibitors targeting eIF4E.

Opsona Therapeutics

Series C in 2013
Opsona Therapeutics is a Dublin-based drug development company specializing in immunology, particularly the modulation of innate immunity pathways. Founded in 2004, the company has developed innovative therapeutic approaches aimed at treating autoimmune and inflammatory diseases, as well as cancer. By targeting the innate immune system, Opsona addresses a spectrum of significant health challenges, including transplant rejection, diabetes, Alzheimer's disease, and atherosclerosis. The company seeks to improve patient outcomes through its novel drug candidates and strategies, positioning itself as a leader in emerging immunology research and drug development in Europe.

Cylene Pharmaceuticals

Series D in 2010
Cylene Pharmaceuticals, Inc. is a biotech pharmaceutical company based in San Diego, California, focused on the discovery and development of small molecule drugs targeting cancer cells. The company specializes in nucleolus targeting agents, which are designed to provide targeted therapeutic solutions for carcinoid and neuroendocrine tumors as well as pediatric brain tumors. Additionally, Cylene develops serine/threonine protein kinase inhibitors and pre-clinical stage oral drug candidates. Established in 1997 as Cyternex, Inc., the company rebranded to Cylene Pharmaceuticals in October 2003. Its innovative approach aims to activate p53 through non-genotoxic pathways, offering improved treatment options for various cancer indications.

PharmAbcine

Series A in 2009
PharmAbcine, Inc. is a biotechnology company based in Daejeon, South Korea, focused on developing fully human therapeutic monoclonal antibodies (mAb) for the treatment of cancer and inflammatory diseases. The company primarily engages in the out-licensing of candidate therapeutics and clinical applications, aiming to create first-in-class and best-in-class mAb. Its key projects include TTAC0001, an anti-angiogenic mAb targeting VEGFR-2, as well as innovative dual-specific antibody technologies such as DIG-body and PIG-body. PharmAbcine has established a strategic partnership with Samsung Biologics for the development and manufacturing of its PMC-403 pipeline, a therapeutic candidate aimed at addressing neovascular disorders. The company leverages a strong management team with expertise in therapeutic antibody discovery and development, supported by renowned scientific advisors in the field.

Opsona Therapeutics

Series B in 2009
Opsona Therapeutics is a Dublin-based drug development company specializing in immunology, particularly the modulation of innate immunity pathways. Founded in 2004, the company has developed innovative therapeutic approaches aimed at treating autoimmune and inflammatory diseases, as well as cancer. By targeting the innate immune system, Opsona addresses a spectrum of significant health challenges, including transplant rejection, diabetes, Alzheimer's disease, and atherosclerosis. The company seeks to improve patient outcomes through its novel drug candidates and strategies, positioning itself as a leader in emerging immunology research and drug development in Europe.

Alios BioPharma

Series A in 2009
Alios BioPharma is focused on discovering and developing innovative antiviral therapies aimed at treating both acute and chronic viral infections. The company utilizes a range of proprietary platform technologies, including small molecule activators of innate immunity, phosphate-protected nucleotide prodrug chemistry, and glycoprotein-engineering of interferons. These technologies enable the development of distinct therapeutic products targeting serious viral conditions such as chronic hepatitis B and C, HIV, and respiratory viruses, including pandemic influenza and emerging diseases like SARS. Alios BioPharma's approach is supported by a proprietary chemical library of nucleoside analogs and advanced virology-based screening systems, positioning the company as a key player in the field of antiviral therapeutics.

Alios BioPharma

Series A in 2009
Alios BioPharma is focused on discovering and developing innovative antiviral therapies aimed at treating both acute and chronic viral infections. The company utilizes a range of proprietary platform technologies, including small molecule activators of innate immunity, phosphate-protected nucleotide prodrug chemistry, and glycoprotein-engineering of interferons. These technologies enable the development of distinct therapeutic products targeting serious viral conditions such as chronic hepatitis B and C, HIV, and respiratory viruses, including pandemic influenza and emerging diseases like SARS. Alios BioPharma's approach is supported by a proprietary chemical library of nucleoside analogs and advanced virology-based screening systems, positioning the company as a key player in the field of antiviral therapeutics.

Intradigm

Series B in 2009
Intradigm is a private biotechnology company specializing in the development of systematic RNA interference (RNAi) therapeutics aimed at treating serious diseases, particularly in the field of oncology. The company leverages its expertise in drug development and delivery to create an innovative RNAi platform. Central to its approach is the proprietary RNAi Nanoplex delivery technology, which allows for the targeted systemic delivery of RNAi therapeutics to specific tissues. Intradigm's portfolio includes a range of siRNA sequences designed to address various oncology and other disease targets, complemented by biodegradable polycationic polymers that enhance the delivery of these therapeutics.

Diagnoplex

Series A in 2008
Diagnoplex has been founded in 2005 supported by seed financing fron the Novartis Forschungsstiftung, Swiss Confederation CTI project, Canton de Vaud FIT and the Gebert Rüf Stiftung. The company has performed a 140 patient prospective pilot study demonstrating technical and clinical feasibility of its colorectal cancer screening test COLOX as well as its high sensitivity and specificity.

Intradigm

Series A in 2006
Intradigm is a private biotechnology company specializing in the development of systematic RNA interference (RNAi) therapeutics aimed at treating serious diseases, particularly in the field of oncology. The company leverages its expertise in drug development and delivery to create an innovative RNAi platform. Central to its approach is the proprietary RNAi Nanoplex delivery technology, which allows for the targeted systemic delivery of RNAi therapeutics to specific tissues. Intradigm's portfolio includes a range of siRNA sequences designed to address various oncology and other disease targets, complemented by biodegradable polycationic polymers that enhance the delivery of these therapeutics.

Hexal

Acquisition in 2005
Hexal is a leading German generic pharmaceutical manufacturer headquartered in Holzkirchen, Bavaria. Established in 1986, the company became part of the Sandoz Group in 2006. Hexal specializes in the development, production, and marketing of a diverse range of products, including patent-free medicines, over-the-counter products, generic drugs, and biosimilars. Biosimilars, which are complex biologics derived from living organisms through biotechnology, represent a significant focus for Hexal, as they require advanced manufacturing techniques and regulatory considerations. With a workforce of over 4,000 employees across six sites in Germany, Hexal is dedicated to providing high-quality medications that meet the evolving healthcare needs of patients.

AGY Therapeutics

Series C in 2004
AGY Therapeutics is a biopharmaceutical company based in South San Francisco, California, founded in 1998. The company specializes in discovering, developing, and commercializing treatments for diseases of the central nervous system (CNS). Its focus areas include neurodegenerative diseases, CNS injuries, stroke, cognitive diseases, and schizophrenia. AGY Therapeutics has a pipeline of novel therapeutic programs, both in clinical and preclinical development, aimed at addressing significant unmet medical needs. The company uses its proprietary platform for functional gene discovery and mapping specific pathways underlying CNS diseases to identify potential target proteins that can modulate disease progression. This approach is designed to pave the way for innovative CNS therapeutics.

Lumenos

Venture Round in 2003
Lumenos is a healthcare company specializing in providing comprehensive wellness solutions. It offers health accounts such as Health Reimbursement Accounts (HRAs) and Health Savings Accounts (HSAs), along with educational resources and incentives to encourage healthier lifestyles. Lumenos' website features health and financial tools, plus a directory of doctors and hospitals. Additionally, it provides personalized health coaching for individuals managing conditions like asthma, diabetes, or heart disease.

Cylene Pharmaceuticals

Series A in 2001
Cylene Pharmaceuticals, Inc. is a biotech pharmaceutical company based in San Diego, California, focused on the discovery and development of small molecule drugs targeting cancer cells. The company specializes in nucleolus targeting agents, which are designed to provide targeted therapeutic solutions for carcinoid and neuroendocrine tumors as well as pediatric brain tumors. Additionally, Cylene develops serine/threonine protein kinase inhibitors and pre-clinical stage oral drug candidates. Established in 1997 as Cyternex, Inc., the company rebranded to Cylene Pharmaceuticals in October 2003. Its innovative approach aims to activate p53 through non-genotoxic pathways, offering improved treatment options for various cancer indications.

Roche

Post in 2001
Roche is a Swiss biopharmaceutical and diagnostics company focused on improving lives through medicines and diagnostic solutions. It develops and markets therapies across oncology, virology, inflammation, metabolism, central nervous system disorders, clinical chemistry, immunology, infectious diseases, and microbiology, and it provides in vitro diagnostics, automated instruments, software, and consumables for hospitals and research labs. The company conducts research and development and manufacturing related to molecular diagnostics, test systems, and test kits, including PCR-based assays through its molecular diagnostics initiatives. Its portfolio includes cancer treatments such as Avastin, Herceptin, and MabThera, and the organization serves hospitals, laboratories, physicians, and patients worldwide with integrated drug and diagnostic offerings. Roche operates globally, combining drug development with diagnostic services to support disease detection, monitoring, and personalized medicine.

AGY Therapeutics

Series B in 2001
AGY Therapeutics is a biopharmaceutical company based in South San Francisco, California, founded in 1998. The company specializes in discovering, developing, and commercializing treatments for diseases of the central nervous system (CNS). Its focus areas include neurodegenerative diseases, CNS injuries, stroke, cognitive diseases, and schizophrenia. AGY Therapeutics has a pipeline of novel therapeutic programs, both in clinical and preclinical development, aimed at addressing significant unmet medical needs. The company uses its proprietary platform for functional gene discovery and mapping specific pathways underlying CNS diseases to identify potential target proteins that can modulate disease progression. This approach is designed to pave the way for innovative CNS therapeutics.

Lumenos

Series B in 2000
Lumenos is a healthcare company specializing in providing comprehensive wellness solutions. It offers health accounts such as Health Reimbursement Accounts (HRAs) and Health Savings Accounts (HSAs), along with educational resources and incentives to encourage healthier lifestyles. Lumenos' website features health and financial tools, plus a directory of doctors and hospitals. Additionally, it provides personalized health coaching for individuals managing conditions like asthma, diabetes, or heart disease.
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