Creative Destruction Lab

Nanology Labs Inc., founded in 2018 and based in Toronto, Canada, focuses on developing a nano-theranostic platform technology aimed at detecting and treating cancers. The company's flagship product, Manganescan, serves as a novel theranostic agent that functions both as an MRI contrast agent and a radio-sensitizer. Manganescan enhances the detection of brain tumors at early stages by producing Mn2+ ions, which oxygenate the tumor environment and improve the efficacy of radiation therapy. This innovative agent is three times more sensitive than existing Gadolinium-based contrast agents and is capable of crossing the blood-brain barrier, allowing for early and precise identification and targeting of brain cancer.

Stockholm Water Technology specializes in creating innovative and sustainable water purification solutions, focusing on capacitive deionization technology. The company combines advanced nanotechnology materials with smart engineering to develop a patented, membrane-free approach to water desalination. This technology is designed to achieve high water recovery rates while minimizing energy consumption and costs, making it a viable option for clients seeking efficient water cleansing and desalination methods. By integrating both hardware and software, Stockholm Water Technology enhances the overall functionality of its systems, promoting environmentally friendly practices in water management.

Kraken Sense develops an automated pathogen detection platform that includes sensors to detect bacterial contamination in real-time, using cutting edge nanotechnology and state of the art calibration techniques. The company's solution makes monitoring low-cost and easy to use with an IoT enabled dashboard and analytics tools.

Pulsenics specializes in real-time electrochemical system monitoring and control solutions, employing artificial intelligence to enhance the efficiency of electrochemical processes. The company's technology offers critical insights into various operational parameters, such as electrolyte concentration, membrane health, power consumption, and electrode adsorption. By facilitating effective process control, Pulsenics aims to improve the quality of final effluent while optimizing maintenance schedules. This focus on operational efficiency not only aids in reducing overall energy consumption but also lowers operating expenditures for businesses involved in electrochemical treatments.

Nfinite Nanotechnology is an advanced materials company specializing in open-air atomic layer deposition (ALD) technology. The company develops functional nanomaterials that facilitate the creation of sustainable solutions, including compostable and recyclable flexible food packaging, batteries, and photovoltaics. Nfinite's innovative nanocoating system produces large-area, high-quality ultrathin films significantly faster and more economically than conventional methods, enhancing the production capabilities for packaging manufacturers. By enabling the development of cost-effective, sustainable packaging, Nfinite Nanotechnology plays a crucial role in promoting environmental responsibility while ensuring product freshness and shelf-life.

Liberum Biotech is a biotechnology company focused on advancing protein manufacturing through proprietary molecular and hardware technologies. Its platform facilitates the rapid production of enzymes, therapeutics, and laboratory reagents, enabling clients to enhance speed and scalability while significantly reducing costs. By leveraging its innovative protein synthesizers, Liberum aims to democratize access to synthetic biology, ultimately transforming existing biologics manufacturing practices and making these technologies more accessible to a broader range of users.

Magnomer is a manufacturer based in Boston, Massachusetts, specializing in innovative magnetic inks aimed at enhancing the recyclability of plastic packaging. Founded in 2017, the company focuses on developing printable magnetizable inks that serve as a design tool for consumer brands and manufacturers. These inks improve the scalability of recycling processes for multi-layer plastics, which are traditionally challenging to recycle. By integrating their magnetic inks into packaging, Magnomer enables recycling facilities to utilize magnetic sorting technology, facilitating the efficient separation of materials. This approach aligns with the principles of the circular economy, promoting better sustainability in packaging without necessitating changes in manufacturing processes.

Aquark Technologies specializes in the development of compact cold-atom systems aimed at advancing quantum applications such as atomic clocks, sensors, and navigation systems. The company employs a unique laser geometry technique, stemming from over a decade of proprietary research at the University of Southampton, to miniaturize these systems to the size of a matchbox. This innovation enables the creation of plug-and-play quantum devices that offer portability and support the integration of quantum technologies into everyday life, paving the way for the next generation of quantum sensing and computing solutions.

Up to 15% of the world’s total energy is spent on industrial-scale chemical separations. This is economically and environmentally inefficient. SEPPURE is disrupting the energy-intensive chemical separation processes, such as distillation and evaporation, through the introduction of novel chemical-resistant nanofiltration membranes. SEPPURE’s sustainable process does not use heat, thus lowering global energy use, emissions, and pollution substantially.

Inchfab specializes in custom microchip manufacturing, offering proprietary tools that cater to the microelectromechanical systems (MEMS) market. The company's microfabrication platform enables clients to prototype and produce low volumes of highly customized microchips economically. By focusing on the semiconductor and micromechanical Internet of Things (IoT) chip markets, Inchfab provides essential manufacturing capabilities that facilitate the design and production of specialized devices.

PionEar Technologies is a medical device company that develops technologies for ear and hearing disorders. Its products include a minimally invasive tympanostomy tube that prevents cellular and bacterial adhesion and improves drug delivery to the middle and inner ears, enabling clients to modernize treatment of chronic ear infections and hearing loss and provide proper treatment services.

Developer of superconductors designed to make the stellarator simple, fusion electricity cheap and MRI a routine medical check-up. The company's high-temperature superconductors (HTS) for use in stellarator plasma devices and medical imaging, put fusion electricity in the grid, enabling clients to make the stellarator simple and fusion electricity cheap.

Navega Therapeutics is a preclinical stage company focused on developing innovative gene therapies aimed at treating chronic pain and addressing the opioid epidemic. The company has created a non-addictive and highly specific gene therapy inspired by a natural genetic mutation in humans that results in an absence of pain perception. In preclinical studies, Navega's therapy demonstrated an increase in pain tolerance and a reduction in pain levels in animal models suffering from inflammatory pain, chemotherapy-induced neuropathic pain, and pain induced by BzATP. Safety assessments indicate that the therapy does not cause neurological, motor, or olfactory side effects. Navega has received funding through two Small Business Innovation Research grants from the National Cancer Institute and the National Institute of Neurological Disorders and Stroke, and has secured three patents from the University of California, San Diego.

Brilliant Matters is a developer and manufacturer focused on providing advanced materials for printed electronics. Founded by material scientists, the company addresses the demand for a reliable supply of next-generation organic semiconductors. Utilizing innovative chemical processes, Brilliant Matters specializes in creating proprietary materials that support the production of organic solar cells, photodetectors, thin-film transistors, and electrochromic devices. Their commitment to developing environmentally friendly solutions positions them as a valuable partner for manufacturers in the electronics sector.

Time is precious and for patients with the most common brain tumour, glioblastoma, the value of that time really comes into focus when they are suddenly hit with the news there is no cure and that they have just one year to live. Current treatment options are not good enough and come at a huge cost to the quality of that remaining time. Our co-founder Dr Richard Fu recognised this and was frustrated not only by the lack of treatments available for his brain tumour patients but also by major design flaws in newer electrotherapy approaches. Working together with Dr Chris Bullock, a biomedical engineer arising from Manchester's world-class materials research centres, they formed an elegant solution designed to optimise patient life-expectancy and quality of life. Together they formed QV Bioelectronics, and since then, their ground-breaking research has received over $425k in financial awards from several UK institutions, including Innovate UK and the National Institute for Health Research in the UK. The technology core patent has been filed, with full FTO. The team has grown to contain commercial expertise that encompasses individuals with a unicon exit in their CV's, as well as multiple startup experience between them. Additionally, alongside Dr Fu's expertise, the clinical advisory board contains some of Britain's top neurosurgeons who are helping to input into the feedback of the technology design. Our aim is to double patient life expectancy compared to standard treatment without impacting quality of life, so patients can focus on what matters. Join us at QV Bioelectronics, in pioneering a better option for terminal cancer patients.

Nia Therapeutics, Inc. is focused on developing neurostimulation therapies aimed at treating memory impairment, particularly in patients who have suffered traumatic brain injuries. Founded in 2016 and based in Philadelphia, Pennsylvania, the company emerged from research at the University of Pennsylvania and was influenced by the United States BRAIN Initiative. Nia Therapeutics specializes in creating devices that analyze complex brain activity linked to memory function, delivering personalized therapy through deep-brain stimulation. This innovative approach seeks to enhance memory by restoring the brain activity essential for effective memory recall.

SpinDrive specializes in the development of advanced levitation technology, focusing on magnetic bearing systems that enhance energy efficiency while promoting oil-free solutions. Their innovative systems include magnetic bearing sensors that monitor shaft positioning and relay this information to a magnetic bearing controller. This technology allows clients to significantly improve system efficiency, reduce material consumption, and lower maintenance costs, making it a valuable solution for industries seeking sustainable and efficient operational practices.

SynchroPET Inc. specializes in the development of innovative Positron Emission Tomography (PET) imaging systems for both medical research and clinical applications. Founded in 2013 and based in Stony Brook, New York, the company offers a range of products including PET/MRI systems for comprehensive preclinical research, a portable Mini-PET device for laboratory mobility, and the RatCAP, which allows for unobstructed animal movement during imaging. Additionally, the Wrist PET Detector is designed for non-invasive clinical use. SynchroPET's technologies aim to enhance diagnostic accuracy and treatment efficacy for diseases such as cancer, Alzheimer's, and Parkinson's by providing improved resolution and quantitative data, thus facilitating personalized medical treatments and accelerating research potential.

Nectar is a company focused on enhancing the health of honey bees and supporting beekeepers through a specialized apiary management platform. This platform utilizes sensors and artificial intelligence to optimize beekeeping operations, allowing beekeepers to provide timely and appropriate care for their colonies. By facilitating communication between bees and beekeepers, Nectar aims to strengthen the relationship between the two, ultimately improving the effectiveness of honey bee pollination on crops. The technology offers key measurements that help beekeepers minimize losses, save time, and cultivate robust apiaries, contributing to sustainable beekeeping practices.

Developer of nanotechnology-based medical products intended to provide biocompatible and bio-selective wound dressings. The company commercializes nanotechnology in the health and decontamination sectors beginning with chronic wounds like diabetic foot ulcers, providing clinicians with small and mighty components to address unmet health needs.

AQT specializes in the development of quantum computer technology aimed at processing information through innovative methods. The company utilizes electric fields and single charged atoms trapped in vacuum chambers to create its quantum systems. Each quantum bit, or qubit, is represented by an ion and is manipulated and measured using precisely timed laser pulses. This technology provides clients with a clear pathway toward large-scale quantum computing solutions, ranging from scalable ion-trap processors to photonic networks that interconnect quantum computers. AQT's advancements position it at the forefront of the quantum computing landscape, offering significant potential for future applications.

SafetyNet Technologies Ltd manufactures light-emitting bycatch-reduction technology electronic devices for the fishing industry. Its product Pisces is a kit of lights that you attach to your fishing gear which uses artificial light technology to alter the behavior of fish and other marine species to catch particular species. SafetyNet Technologies Ltd was incorporated in 2011 and is based in London, United Kingdom.

Niricson is a company that specializes in infrastructure asset management through the use of robotics and computer vision technology. It offers a predictive asset management platform that enables infrastructure owners to inspect structures more efficiently and with greater accuracy. The platform provides users with valuable insights, allowing for proactive planning of repairs and effective budget management. This service is particularly beneficial for hydro dam owners and engineering consulting firms, as it enhances their ability to ensure the safety of critical structures throughout their service life while also reducing operational costs.

Diadem Biotherapeutics is a biotechnology company that focuses on creating bio-therapeutical materials produced using organic means. Diadem develops exosomes to treat chronic inflammatory and auto-immune conditions.

Kuano Ltd provides quantum and AI solutions for molecular designs. It designs inhibitors to combine quantum simulation and machine learning approaches to create effective inhibitors based on the mechanisms of the target enzyme. It designs and selects modules in various sectors, including pharma, crop protection, and industrial chemistry. The company was incorporated in 2020 and is based in London, United Kingdom.

Virocarb is a science-driven biotech company focused on the development and commercialization of innovative drugs for viral infections with urgent unmet therapeutic needs.

Ki3 Photonics Technologies is an optical quantum technology that targets the generation and manipulation of non-classical photons, necessary for the development and commercial success of quantum technologies.

Neurolytic Healthcare Ltd. is a company based in Oxford, United Kingdom, specializing in the design, development, manufacturing, and delivery of digital and genomic-based diagnostic tools and medical devices aimed at treating migraine and related neurological disorders. Established in 2016, the company focuses on personalized medicine by integrating genetic and biomarker data to enhance diagnostic accuracy and assist clinicians in determining optimal treatment strategies. Its product offerings include a diagnostic support tool, a pharmacogenetic test, and a mobile application designed for predicting migraine events. Through these innovative solutions, Neurolytic Healthcare aims to improve the management and treatment of neurological conditions.

Dynami is a technology company that enables batteries tailored to the product design instead of the product designed for the batteries. It also offers technology development, full-service engineering, and customized designs to partners. Dynami developing batteries for devices such as the Internet of Things (IoT), wearable technology, sensors, and medical devices. The company leverages the regional availability of lithium, research, and engineering resources to create proprietary battery technology and production processes for its clients. Dynami was founded on March 13, 2017, and is headquartered in Buenos Aires, Argentina with an office in Washington, DC, USA.

Granville Biomedical is a health tech company, specializing in the design of anatomical models to enhance health care training, advance patient education, and innovate device demonstration. Through extensive research and development involving mechanical, simulation, and biological testing, Granville Biomedical has designed a novel, biocompatible Nasopharyngeal (NP) swab for nasal specimen collection.

OrganoTherapeutics is a company focused on developing medical drugs aimed at treating Parkinson's disease. It utilizes advanced human-specific mini-brain models that accurately replicate the pathology of Parkinson's disease for the discovery and development of effective drug candidates. By employing three-dimensional models derived from both healthy individuals and patients with Parkinson's disease, OrganoTherapeutics identifies the therapeutic potential of various compounds and analyzes data using artificial intelligence. This innovative approach facilitates the screening of new molecules, allowing researchers to advance novel drug candidates. The company has already developed proprietary drug candidates and has access to extensive libraries for further research and development.

Developer of nanotechnology designed for the agriculture industry. The company's technology improves food safety through the development of novel methods for cleaning and sanitizing, enabling clients with the feasibility of employing nanotechnology to replace traditional post-harvest chlorine wash.

Summit Nanotech Corporation is a business-to-business company based in Calgary, Canada, founded in 2018. It specializes in nanotechnology to develop innovative solutions for lithium extraction, aiming to optimize operations for lithium producers while minimizing environmental impact. The company's patented extraction technology is designed to deliver economically competitive, battery-grade lithium, addressing the industry's demand for sustainable practices. By focusing on modular commercial systems, Summit Nanotech seeks to upscale and commercialize its advanced concepts in lithium extraction, positioning itself as a leader in the energy development sector.

Edgehog specializes in anti-reflection technology aimed at improving the viewing experience of electronic displays. The company has developed a scalable method for fabricating bio-inspired nanostructures directly onto the native glass or plastic surfaces of displays. This innovative approach achieves uniform anti-reflectivity across the visible spectrum, significantly reducing glare in various environments. By implementing this technology, Edgehog enhances the usability of devices such as smartphones and watches, allowing users to see displays clearly even in bright outdoor sunlight. Additionally, their solution decreases the display's brightness while preserving high contrast and extending battery life, thereby providing a more efficient viewing experience.

Developer of aircraft braking systems intended to provide frictionless and virtually wear-free braking. The company's magnetic brake technology provides completely contactless, wear-free, and maintenance-free braking of large passenger jets, enabling airline companies to save cost in maintenance and operating costs per plane.

Arylla Inc. is a Canadian company established in 2015 that specializes in nanotechnology-based invisible ink designed for fraud detection in luxury goods. The ink enables resellers to verify the authenticity of items such as leather goods, footwear, and ready-to-wear clothing. Arylla collaborates with luxury brands, applying the invisible ink during the production process, allowing these brands to monetize the resale of their products while combating counterfeit sales. In addition to the invisible ink, Arylla offers a tiered security platform for printing invisible labels that assist in food authentication and develops scanners for verifying fluorescent signatures.

Developer of cryopreservation system designed to preserve small molecules used in clinical research and studies. The company designs and manufactures patented ice recrystallization inhibitors for use in the cryopreservation of cells, and tissues that maintain cellular function after extended frozen storage, thereby enabling physicians to use less costly storage and transportation systems for cell therapeutics.

FluoretiQ Limited is a medical device company based in Bristol, United Kingdom, that focuses on developing advanced technologies for the rapid identification of harmful bacteria. Founded in 2017, the company has created a diagnostic platform known as NANOPLEX, which utilizes proprietary nanomaterials and optical sensing technologies to detect bacterial pathogens in under 15 minutes. This innovative approach combines receptor-mediated sensing with quantum-enhanced optics, facilitating early diagnosis and enabling healthcare professionals to prescribe effective antibiotic treatments more efficiently. FluoretiQ's user-friendly products support accurate same-day diagnoses, ultimately improving patient outcomes by ensuring timely and appropriate antibiotic selection.

Nth Cycle is a start-up focused on transforming the electronics manufacturing supply chain through innovative low-cost recycling methods. The company aims to shift the industry from a linear material model to a more efficient circular model, thereby reducing dependence on overseas mining and refining of rare earth and specialty metals. By developing an electrochemical recycling device, Nth Cycle enables the reclamation of valuable metals from end-of-life electronic devices, creating a secure domestic source for these materials. This approach not only supports the manufacturing sector but also contributes to advancements in clean energy, addressing the growing demand for sustainable practices in the recycling and electronics industries.

Developer of a cell-targeted nuclease drug designed to provide precision gene alteration. The company's platform offers a novel cell-targeted nuclease approach for therapeutics that addresses the fundamental challenges faced by CRISPR-based gene editing and allows for exquisite polyvalence in targeting and significantly shortened target identification phases in drug discovery, enabling healthcare clients with immunogenicity, safety, and cost-effective products.

Developer of novel gene-editing technologies designed to treat diseases at the genetic level in cells inside the body. The company's technology consists of a dual-cleaving nuclease that can be delivered to cells to treat various genetic diseases, enabling customers to exploit the cell's naturally occurring DNA repair pathways through enhanced repair or predictable deletions.

Developer of a technology-based platform designed to enhance performance via sustainable and economic carbon nanofibers. The company's platform has developed a proprietary chemical process technology to convert carbon dioxide and waste heat from power plants into high-strength carbon fiber, enabling industries to use greenhouse gas feedstocks annually and turning them into sustainable and valuable solid commodities.

Nucleome Therapeutics is a biotechnology company transforming drug discovery using the 3D structure of the genome. The pioneering genomics platform uses the 3D structure of the genome and ML-powered computational genomics to decode and mine the regulatory “dark matter” of the human genome to help deliver the next generation of genetically guided therapeutics. They harnessing the nucleome to unlock the non-coding genome for human health. Nucleome Therapeutics was founded in 2019 and is headquartered in Headington, Oxford, United Kingdom.

Epineuron Technologies, Inc. is a medical device company based in Hamilton, Canada, focused on developing innovative treatment solutions for peripheral nerve injuries. Founded in 2016, Epineuron is pioneering bioelectronic medicine with a mission to set new standards in nerve repair and regeneration. The company is creating a range of surgical solutions, including an electroceutical device that provides electrical stimulation to enhance the natural healing processes of injured peripheral nerves. By accelerating nerve regeneration, Epineuron aims to offer patients advanced care options and aims to establish itself as a leader in the field of bioelectronic nerve therapy.

At Phaseshift, we develop novel high performance alloys using Computational Chemistry and Machine Learning. Our Machine Learning models are trained to predict material properties associated with a large range of alloy compositions in a a few seconds. This, along with our computational chemistry models, enable us to model the behavior of any alloy composition in a time and cost efficient way without any compromises with the accuracy. We use our solution to develop materials for our clients that have a very specific set of needs that are unmet by existing material choices. Currently we are focused on a specialized class of materials - Amorphous Alloys and High Entropy Alloys. These materials are often considered as some of the toughest materials known to us but are less easily commercialized than traditional alloys. Some use cases of these alloys are found in the bio-medical industry, aerospace industry, nuclear industry, etc. We can also optimize our materials for the ever evolving manufacturing landscape and are currently working on projects that involve optimizing are materials for Additive Manufacturing.

Menten AI, Inc. is an early-stage drug discovery company based in San Francisco, California, with an additional location in Toronto, Canada. Founded in 2018, the company focuses on developing protein-based drugs and enzymes using advanced technologies, specifically machine learning and quantum computing. Menten AI addresses the complex challenge of designing proteins, which can adopt numerous shapes, by leveraging quantum computing to represent multiple protein states simultaneously. This innovative approach allows for more efficient identification of optimal protein designs. The company has achieved significant milestones, including creating the world’s first peptide designed on a quantum computer, and is currently working on peptide therapeutics aimed at treating oncology and neurodegeneration, as well as enzymes for various industrial applications.

Evercloak Inc., founded in 2018 and based in Waterloo, Canada, specializes in the production of ultra-thin graphene and other two-dimensional nanomaterial films. The company employs an economical and energy-efficient manufacturing process to create continuous coatings of single-layer nanomaterials. By utilizing an advanced manufacturing platform, Evercloak produces ultra-thin nanomaterial membranes that support clean technology applications. These innovations aim to lower costs, reduce energy consumption, and decrease greenhouse gas emissions across various sectors, including oil and gas, nuclear energy, mining, and agri-food.

Operator of a biotechnology company intended to tailor the activity and stability of proteins and enzymes for a range of applications. The company mainly focuses on research and development and direct product sales in the merged field of proteins and polymers to utilize atom transfer radical polymerization chemistry to grow polymers with precision from the surface of proteins, enabling physicians to discover an effective alternative for therapeutics and protein engineering.

CellFE Inc. is a San Carlos, California-based company that specializes in the development of a microfluidics-based device designed to deliver gene-editing molecules into human cells. Founded in 2017, CellFE's innovative platform employs rapid cell compressions to enhance the uptake of therapeutic molecules from the surrounding fluid, facilitating the development and manufacturing of advanced cell therapies. This technology aims to address previously inaccessible cell therapies, enabling medical researchers to transport difficult-to-deliver molecules into cells for the treatment of various disorders, ultimately improving patient outcomes.

Synthergy develops physics-based software that allows for the simulation of advanced semiconductor industry product manufacturing.

Synergia Biotech is a cleantech venture that uses a community of microbes to remove CO2 from the atmosphere and produce a natural, vibrant blue pigment (phycocyanin) that can replace chemical coloring additives in the food and cosmetic industries. Synergia Biotech’s technology is backed by years of cutting-edge scientific research in ecology, microbiology, and engineering. Blue is one of the rarest colors found in nature and phycocyanin has emerged as the most viable source to replace chemical and synthetic versions in industry. From removing carbon dioxide in the atmosphere to recycling nutrients and water in our system, Synergia Biotech is poised to be a global leader in climate-positive technology.

Redesign Science Inc is a biotechnology company based in New York, established in 2017, that specializes in small molecule drug discovery. The company employs advanced techniques, including first-principles physics and artificial intelligence, to simulate protein targets at the atomic level. This approach allows Redesign Science to identify subtle drug opportunities that conventional computational models may overlook. By focusing on the development of first-in-class small molecules, the company aims to address emerging and challenging targets associated with significant unmet medical needs. Their innovative methodologies not only enhance the understanding of biological pathways and disease mechanisms but also drive the commercialization of new therapeutic solutions.

Syzygy Plasmonics is a developer of a photocatalytic reactor designed for fuel cell vehicles and small-scale industrial applications.The company's reactor is powered by light and operates at over 1,000°F lower temperature than conventional chemical reactor technology that helps in reducing maintenance costs and is able to start or stop production near instantaneously, enabling fuel cell vehicle companies to produce ultra-low-cost hydrogen gas on-site at customer locations.

Nplex Biosciences is a biotechnology company based in the United States that specializes in proteomic technology. The company has developed a platform that utilizes DNA nanotechnology to understand, detect, and treat diseases. Nplex offers a range of instruments and automation tools for measuring multiple proteins from blood samples, providing cost-effective solutions for protein data analysis. Its technology integrates seamlessly with industry-standard cytometers, enabling high-throughput analysis and the development of custom protein panels. Nplex aims to enhance existing instruments and workflows while facilitating automation in proteomic research and applications.

Coastal Genomics Inc. engages in research and development for the life sciences automation sector. The company offers ranger technology, than enables the complete automation of gel based size selection of biomolecules. The company was incorporated in 2012 and is based in Burnaby, Canada.

Developer of novel skin regeneration cosmetics designed to assist in the safe treatment of skin wounds. The company's cosmetics are based on a gel-patented technology that allows full epithelial restoration, helping to close wounds quickly and with minimal scarring and reduce redness and bruising, enabling users with post-procedure and post-surgical scarring prevention, and reducing complications and risks associated with slow healing.

Click Materials Corp., now known as Miru Smart Technologies, is a Vancouver-based company specializing in advanced materials and innovative thin film production. Founded in 2011, the company focuses on manufacturing films that enhance energy efficiency, particularly through products like electrochromic windows, which can switch between clear and opaque states using electricity. This technology is designed for smart home applications and aims to lower power consumption. With a foundation in over a decade of academic and industrial research, Miru Smart Technologies is advancing its fabrication processes and establishing strategic partnerships across residential, commercial, and automotive sectors to optimize performance while reducing manufacturing costs.

Nodes & Links is a technology company focused on helping organizations navigate project complexity by offering a reporting platform that forecasts and manages risks. Utilizing artificial intelligence, the platform generates reports, tracks progress, analyzes impacts, identifies data discrepancies, and provides prediction graphs. This functionality is particularly beneficial for the construction industry, enabling stakeholders to make informed decisions quickly and improve project outcomes. Through its innovative solutions, Nodes & Links aims to empower businesses to address the challenges associated with complex project interactions effectively.

Razzberry is creating breakthrough technologies in microsensing to change the way we interact with ourselves and our world.

Developer of lithium-ion batteries designed for wearable and printed electronics companies. The company's batteries can be bent, rolled, and twisted into any shape and are created for wearable and printed electronics companies that are experiencing design issues caused by traditional batteries, enabling companies to get the freedom to create products that are aesthetically appealing to their customers.

Nanogrande offers a disruptive technology for the 4.0 industrial revolution high definition manufacturing with its services, devices and powders. Our devices offer a wide range of freedom in design, as well as a broad variety in the materials that can be used. Our patented process allows the production of particle layers as thin as one nanometre, creating 3D objects with unprecedented definition. This way, we developed the world first nanoscale 3D printer! The multiple material capacity extends to size, shape and nature, which is currently impossible by other competing technologies. We therefore can work with metals, polymers and ceramics. These unique technological feats open us the door to manufacturing solutions that can claim a fair part of the fast-growing multibillion-dollar market of Metal injection moulding (MIM), precision metal casting, as well as passive components for Microelectromechanical systems (MEMS). We are bridging nanotechnology and additive manufacturing.

PTScientists is a private space technology company focussed on enabling cost-efficient and widely usable access to space by bringing down the costs of space missions. The ALINA spacecraft is at the heart of our mission technology enabling a wide range of commercially viable infrastructure assets such as a 4G network basestation developed in cooperation with Vodafone and the Nokia Bell Labs.

Strand Therapeutics Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2017. The company focuses on genetically programming mRNA to develop innovative therapies that enhance patient outcomes. Utilizing its mRNA programming technology, Strand Therapeutics creates gene therapies powered by synthetic biology, which include immunotherapies designed to stimulate cells to produce cancer-targeting proteins. This approach improves the immune system's ability to combat cancer by enabling precise control over the timing, location, and intensity of therapeutic protein expression. The technology leverages cell-type specific expression and responds to specific molecular signals, allowing for tailored therapeutic interventions.

Obatala Sciences, a fat-on-a-chip biotechnology company, was incorporated to reduce the $2 Trillion economic burden associated with Obesity and Diabetes. Obatala is revolutionizing our view of body fat by highlighting its importance as a functional organ, and a regulator of body health and disease.

Nanology Labs Inc., founded in 2018 and based in Toronto, Canada, focuses on developing a nano-theranostic platform technology aimed at detecting and treating cancers. The company's flagship product, Manganescan, serves as a novel theranostic agent that functions both as an MRI contrast agent and a radio-sensitizer. Manganescan enhances the detection of brain tumors at early stages by producing Mn2+ ions, which oxygenate the tumor environment and improve the efficacy of radiation therapy. This innovative agent is three times more sensitive than existing Gadolinium-based contrast agents and is capable of crossing the blood-brain barrier, allowing for early and precise identification and targeting of brain cancer.

Developer of a portable neuroimaging system designed to track and predict recovery of movement function during the rehabilitation of hemiparesis. The company's systems utilize a proprietary optical imaging system, assessment software, and data analytics to measure neural biomarkers and aid neurological rehabilitation, enabling therapists to make sustainable treatment decisions.

NoPo is working towards a vision of making space accessible to everyone by mass producing the ideal material for spacecraft construction; Single Walled Carbon Nanotubes. Carbon Nanotubes would help decrease mass fraction allowing for increased payloads and a safer trip. The company developed the proprietary NoPo HiPCO technology to produce Nanotubes consistently and at scale.

Click Materials Corp., now known as Miru Smart Technologies, is a Vancouver-based company specializing in advanced materials and innovative thin film production. Founded in 2011, the company focuses on manufacturing films that enhance energy efficiency, particularly through products like electrochromic windows, which can switch between clear and opaque states using electricity. This technology is designed for smart home applications and aims to lower power consumption. With a foundation in over a decade of academic and industrial research, Miru Smart Technologies is advancing its fabrication processes and establishing strategic partnerships across residential, commercial, and automotive sectors to optimize performance while reducing manufacturing costs.

Developer of diamond-based quantum sensors intended to prevent contaminant leaks from mining, oil, gas, and waste management industries. The company deploys compact technology into novel platforms making high-precision magnetic field mapping and diagnosis of magnetic signals accessible to a large user base, enabling miners to understand and navigate through the environment.

Synex Medical specializes in non-invasive blood testing technology, focusing on the development of a portable device that enables users to monitor metabolite concentrations without penetrating the skin. Utilizing a miniaturized magnetic resonance system, the company can accurately detect critical blood metabolites such as glucose, lactate, and ketones. This innovative approach employs only magnets and radio waves, ensuring there are no adverse health effects associated with its use. By providing precise information about metabolic health, Synex Medical aims to empower individuals to take proactive steps in managing their health and well-being.

SaluTech develops a conductive biomaterial (CBM) to treat the underlying cause of the arrhythmia. This CBM has the ability to reduce/diminish arrhythmia while being nontoxic, biocompatible, and inexpensive to produce.

Sankoya Technologies specializes in innovative sanitation solutions, focusing on the development of a next-generation toilet that transforms human waste into pathogen-free ash. By employing an intellectual property licensing strategy, the company aims to integrate its off-the-grid sanitation technology into various sanitation services. This approach is designed to address the needs of over 2.5 billion people globally who lack access to basic toilet infrastructure and reliable sanitation facilities, particularly in areas with limited resources. Through its efforts, Sankoya seeks to improve hygiene and health outcomes in underserved communities.

Naegis Pharmaceuticals Inc. is a Canadian biopharmaceutical company focused on developing innovative small molecules to treat serious inflammatory diseases, particularly those affecting the eyes. Chronic inflammatory diseases pose significant health challenges, especially in an aging population, impacting both quality and quantity of life. Naegis's research team is dedicated to creating new therapies that target the underlying inflammatory processes associated with these conditions. The company’s initial focus is on serious eye diseases that can damage the back of the eye, aiming to block the synthesis of pro-inflammatory mediators. By designing a series of compounds that can be delivered to the retina through eye drops, Naegis seeks to provide safer and more effective treatment options for conditions that are leading causes of blindness.

MesoMat specializes in advanced sensing technology, focusing on the development of plastic-based fibers that serve as lightweight strain sensors. These innovative fibers are designed to monitor fatigue, fracture, and failure in critical material systems. By integrating these sensing fibers with custom electronics and software, MesoMat provides a comprehensive condition-based monitoring platform that leverages real-time data to prevent material failure. The fibers can be easily embedded into various materials, including those in high-strain environments that are typically difficult to access with traditional strain sensors. MesoMat's technology aims to enhance safety and efficiency in numerous applications, particularly in sectors where material integrity is crucial.

uFraction8 specializes in scalable bioprocessing technology that enhances biomass filtration, separation, and dewatering. The company's innovative approach utilizes microfluidic devices to efficiently process a wide range of microbes, including microalgae, yeast, and bacteria. Unlike traditional methods such as centrifuges, filters, and membranes, uFraction8's technology sorts biomass from culture media without causing harm and without the use of flocculants. This advanced cell separation technology enables industries to achieve higher throughput and reduce costs compared to conventional liquid processing methods. By focusing on industrial-scale applications, uFraction8 provides solutions that streamline operations in various sectors while maintaining efficiency and effectiveness.

nPlan Limited specializes in developing artificial intelligence-based software for construction project management. Founded in 2017 and headquartered in London, the company employs machine learning technology to enhance schedule reliability by analyzing past project performances. Its software identifies risks by detecting inconsistencies in task execution patterns and offers recommendations to mitigate these issues. Additionally, nPlan provides statistical insights into risk attribution for individual activities, helping project managers make informed decisions for future construction endeavors.

Cohesys uses inspiration from nature to create the next generation of surgical adhesives that are strong enough to replace titanium screws in craniomaxillofacial (CMF) fracture fixation. Its technology employs a resorbable, flexible polymer tape and bio-inspired adhesive system, resulting in safer and faster CMF fracture fixation procedures.

Zennea Technologies develops therapeutic wearable that reduces snoring and improve health through sleep. The company is based in Surrey, Canada.

Mediphage Bioceuticals is a biotechnology company specializing in non-viral gene delivery solutions for gene therapy, cell engineering, and gene editing. The company’s flagship technology, ministring DNA (msDNA), is designed to be a safe and effective transgene delivery vector that addresses the limitations of traditional viral gene therapies. msDNA offers a versatile platform that can be produced at a significantly lower cost compared to existing options, making it an attractive alternative for researchers. By focusing on innovative solutions for genetic and infectious diseases that have limited or no treatment options, Mediphage Bioceuticals aims to enhance the effectiveness of gene delivery while ensuring patient safety.

Pancella Inc. is a biotechnology company based in Mississauga, Canada, founded in 2015. The company specializes in developing innovative cell therapy solutions, particularly its FailSafe cell therapy system, which is designed to improve treatment outcomes for degenerative and malignant diseases. Pancella's approach focuses on creating cells equipped with unbreakable safety switches, allowing for precise control over cell proliferation. This technology links a drug-inducible suicide gene to a gene critical for cell division, enabling clinicians to effectively eliminate potentially malignant cells before or after transplantation. Through these advancements, Pancella aims to enhance decision-making for regulators, clinicians, and patients in the realm of cellular therapies.

Notch Therapeutics Inc. is an immune cell therapy company based in Toronto, Canada, focused on developing gene-edited allogenic T cell therapies for cancer treatment. Established in 2018, the company utilizes an induced pluripotent stem cell (iPSC) platform that enables precise control of Notch signaling. This innovative technology addresses key limitations in cell therapy development by allowing for the design and manufacture of a consistent supply of therapeutic T cells. Notch Therapeutics specializes in iPSC AlloCAR therapy products aimed at treating conditions such as non-Hodgkin lymphoma, leukemia, and multiple myeloma, enabling healthcare professionals to engineer stem cells tailored to the specific biological challenges presented by complex diseases.

Ionomr Innovations Inc. is a Vancouver-based company specializing in the design, adaptation, and manufacture of advanced ion-exchange membranes and polymer technologies. Founded in 2013, Ionomr focuses on creating environmentally friendly materials that replace toxic fluorinated chemicals often used in electrochemical applications. Its flagship product line, Aemion, is designed for various applications, including water treatment, energy storage, and clean energy generation. The company’s innovative membranes are known for their alkaline stability, strength, and performance, enabling optimal integration into electrochemical systems. By providing solutions that enhance efficiency and reduce environmental impact, Ionomr aims to support the decarbonization of the planet and foster the development of sustainable systems in the renewable energy and circular chemical economies. Additionally, Ionomr offers chemical engineering services to further support its clients in achieving their operational goals.

ProteinQure Inc. is a biotech company based in Toronto, Canada, founded in 2017. The company focuses on developing and manufacturing protein-based therapeutic drugs through innovative technologies such as quantum computing, molecular simulations, and reinforcement learning. ProteinQure employs a computational platform to design novel therapeutics, aiming to transform the drug discovery process by engineering drugs rather than relying solely on traditional methods. The company specializes in the design of exotic peptides with potential applications in treating various diseases, including cancer, diabetes, asthma, and cardiovascular conditions. By partnering with industry leaders in drug discovery, ProteinQure seeks to generate innovative therapeutics that extend beyond conventional chemical approaches.

Nano-Lit Technologies specializes in the design and manufacture of smart lighting products aimed at enhancing health and well-being while significantly reducing energy consumption. The company focuses on creating tunable, full-spectrum circadian rhythm lighting that helps individuals realign with their natural biological rhythms. This innovative approach not only optimizes the visual environment for the human eye but also seeks to improve productivity and engagement across various sectors, including government, offshore, general office workplaces, and healthcare. By prioritizing both environmental sustainability and human health, Nano-Lit Technologies positions itself as a leader in the smart lighting industry.

Chinova Bioworks Inc. specializes in developing natural antimicrobials for the beverage industry, focusing on enhancing the shelf life of fresh juices. Founded in 2016 and based in Fredericton, Canada, the company utilizes a chitosan polymer derived from fungal-sourced technology, specifically natural fibers from mushrooms. This broad-spectrum preservative effectively protects products from spoilage while remaining a healthy, natural ingredient suitable for use in foods, beverages, cosmetics, and personal care items. By providing manufacturers with a solution to improve product quality and freshness, Chinova Bioworks aims to increase consumer satisfaction and reduce food waste.

Graphite Innovation & Technologies is a prominent Canadian materials engineering firm dedicated to advancing the use of graphene and nanomaterials. The company specializes in developing innovative applications for these materials, leveraging its proprietary "bottom up" production process to create high-quality graphene. By owning the intellectual property related to this process, Graphite Innovation & Technologies ensures that it can deliver customized engineered materials tailored to specific client needs. The firm focuses on reducing production costs while enhancing the properties of graphene, enabling businesses to integrate these advanced materials into their products. With expertise in dispersion and product integration, Graphite Innovation & Technologies provides comprehensive solutions that empower clients to enhance their offerings with the unique characteristics of graphene.

Mekonos Inc. is a technology company based in San Francisco, California, focused on the design, development, and production of gene and cell therapies. Founded in 2017, Mekonos has developed a proprietary cell-engineering platform that utilizes scalable silicon technology and an integrated system-on-a-chip. This platform enables the creation of predictive models for drug discovery and development, as well as a silicon chip automated architecture for genome editing. The company's innovative MEMS technology allows for the precise control of individual nanoneedles to inject single cells in parallel, facilitating the industrialization of engineered therapies for genetic diseases, including cancers. By providing a reliable and reusable manufacturing system, Mekonos aims to enable healthcare providers to deliver a diverse range of therapeutic molecules across various primary cell types.

Oncoustics focuses on enhancing clinical workflow productivity and increasing the accessibility and affordability of ultrasound technology for diagnostic imaging. The company has developed advanced artificial intelligence solutions that analyze raw ultrasound signals to identify differences between healthy and diseased tissues, thereby revealing novel acoustic biomarkers. This innovation allows medical professionals to categorize tissues effectively, serving as a virtual biopsy system and addressing significant unmet clinical needs in disease treatment monitoring. By making ultrasound technology available to non-experts, Oncoustics aims to improve diagnostic capabilities in various healthcare settings.

NanoQuan Inc. is a Kitchener, Canada-based company specializing in the development of nano-composite materials and processing technologies applicable to various sectors, including electronics, automotive, and aerospace. As a spin-off from the University of Waterloo, NanoQuan leverages a leadership team with extensive experience in nanomaterial innovation, particularly in water and air filtration, as well as porous membrane and separation technologies. The company's unique dispersion-mixing technology integrates nano-fillers into diverse host materials, resulting in products with exceptional electrical, mechanical, optical, and thermal properties. NanoQuan's achievements in innovation and commercialization are supported by a robust portfolio of intellectual property, with seven patents and numerous peer-reviewed publications. The company has attracted interest from prominent industry partners, reflecting its significant impact in the field of advanced materials.

Mesentech Inc. is a regenerative medicine company based in Vancouver, Canada, that specializes in developing novel drug conjugates for targeted bone therapy. Founded in 2013, the company utilizes a proprietary prodrug platform that selectively delivers therapeutics to bone, addressing challenging medical conditions such as osteoporosis and Duchenne muscular dystrophy. Its lead product, MES1007, is a bone-targeted prodrug of a prostaglandin mimetic designed to reverse bone loss by effectively targeting mesenchymal stem cells. This innovative approach enables the delivery of active pharmaceutical agents directly to the bone, minimizing systemic side effects often associated with high-dose treatments. Pre-clinical in-vivo models have validated the efficacy of Mesentech's technology, positioning the company to advance treatments for low-bone-density disorders and improve outcomes in bone healing and regeneration.

See-Through Scientific

Carbon Upcycling Technologies (“CUT”) was formed to use the pollution of today to build the materials of tomorrow by converting CO2 gas into solid products. CUT sells advanced solid products derived from greenhouse emissions and cheaply available solids. Since 2014, CUT has scaled its ability to capture CO2 emissions from point sources, such as power plants, by over a million times and has technically validated the performance of its end products in over 10 different industrial markets. Through its portfolio of CO2-derived solid nanoparticles, CUT has technically validated its solutions for use in the plastics, coatings, epoxy, adhesives, concrete, lithium-ion battery, and pharmaceutical industries. CUT commercialized a corrosion-resistant coating, utilizing its nanoparticles, in 2017, becoming the youngest CO2 utilization company to generate commercial revenue (<2.5 years since inception) and has since been confirmed as one of the top CO2 utilization companies in the world as one of the 10 Carbon X-Prize Finalists. CUT has been named as a Solar Impulse Efficient Solution label recipient, a funding recipient of Fundación Repsol Entrepreneurs Fund, and a winner of the 2019 76West Clean Technology Competition.

Neuraura Biotech Inc., founded in 2017 and based in Calgary, Canada, focuses on developing neuro sensors for neuro-modulation and brain-machine interfacing to assist individuals with neurological, psychiatric, and sensory disorders. The company’s flagship product is a brain monitoring platform designed for epilepsy surgery, which integrates proprietary electrodes, wireless EEG hardware, and 3D visualization software. This platform aims to enhance patient experiences and outcomes while alleviating the workload of clinicians and reducing healthcare costs. In addition to its work in epilepsy, Neuraura is utilizing its advanced micro-electrodes to explore personalized bio-electronic medicine, targeting conditions such as polycystic ovary syndrome to improve women's metabolic and reproductive health through wearable devices. By leveraging unique electrophysiological data from patients, Neuraura seeks to advance the field of neuromodulation for broader applications.

Interface Fluidics is an international technology company that specializes in reservoir fluid analysis services. Utilizing a proprietary nanofluidic technology platform, the company provides innovative solutions for oil and gas producers to enhance their understanding of reservoir properties. By focusing on microfluidic reservoir modeling and fluid characterization, Interface Fluidics evaluates the effectiveness of new processes and fluid interactions. This comprehensive analysis helps clients make informed production decisions and ultimately aims to optimize oil production and increase overall productivity in the industry.

Nix, Inc. is a consumer diagnostic company based in Boston, Massachusetts, that specializes in the manufacture of single-use biosensing wearable technologies designed to monitor hydration levels. The company has developed a sweat-based biometric sensor that provides real-time insights into hydration status and electrolyte loss, catering primarily to athletes, soldiers, and laborers. This innovative sensor enables users to optimize their performance by accurately assessing their fluid needs during training and competition. Founded in 2015, Nix aims to empower individuals to make informed decisions about their hydration.

Xanadu Quantum Technologies Inc., founded in 2016 and based in Toronto, Canada, specializes in developing photonic quantum computers. The company integrates quantum silicon photonic chips into existing hardware to create full-stack quantum computing solutions. Xanadu offers several software tools, including PennyLane, a Python library for quantum machine learning and hybrid quantum-classical computations, and Strawberry Fields, an open-source programming language for quantum computing. The company aims to make quantum computing accessible and beneficial by addressing real-world challenges and enhancing computational capabilities beyond classical methods. By combining expertise from leading scientists and industry professionals, Xanadu is positioning itself as a significant player in the quantum technology landscape.

H2nanO Inc. is a Canadian company focused on developing advanced wastewater treatment technology for municipal and industrial applications. Founded in 2015 and headquartered in Kitchener, with an additional office in Waterloo, the company specializes in creating nonmaterial and nanotechnology products designed to effectively treat hard-to-degrade water contaminants. H2nanO's innovative approach utilizes light-activated processes, enabling safe discharge and reuse of treated water.

QuWare is powering next-generation photonic technologies.

ICSPI Corp. manufactures scanning probe instruments on a CMOS-MEMS technology platform. Its product nGauge Atomic Force Microscope (AFM) is used to integrate all of the essential components of an atomic force microscope. The company was founded in 2007 and is based in Waterloo, Canada.