MassChallenge

InnoPsych is a mental health platform focused on addressing racial disparities in therapy and promoting emotional wellness within communities of color. The company provides a national directory of therapists of color, enabling individuals to easily find mental health professionals based on geographic location, therapy type, insurance, and personal background. InnoPsych also offers engaging programming designed to reshape conversations about mental health in BIPOC communities, along with wellness products that teach emotional wellness strategies. Through these initiatives, InnoPsych aims to transform the experience of therapy and make mental health resources more accessible and relevant to diverse populations.

Oculogenex is a biopharmaceutical company based in La Habra, California, established in 2020. The company specializes in developing gene therapies specifically aimed at treating retinal disorders. Its innovative approach involves ocular regenerative gene therapy that protects retinal pigment epithelial cells from oxidative stress-induced damage, which is a contributing factor to macular degeneration. By focusing on these therapies, Oculogenex aims to enhance the detection and treatment of various retinal disorders, ultimately supporting researchers in advancing novel drug solutions in this critical area of healthcare.

In a world where you can swipe for anything, Unmute is a platform that makes the process of finding a therapist just as easy. For therapy seekers, we match them to the right therapist quickly through a proprietary algorithm. For therapists, we cut down their administrative work by pre-screening and connecting them to well-suited clients only. It’s free for therapists to join Unmute’s network and they only pay for each matched client that they’d like to connect with upon reviewing a client’s summary.

CardMedic is a healthcare platform designed to enhance communication between healthcare staff and patients, addressing various barriers such as language differences, visual and hearing impairments, cognitive challenges, and literacy issues. The platform features a comprehensive library of digital flashcards that replicate clinical conversations on common healthcare topics. These flashcards are available in multiple formats, including multilingual options, sign language, easy-to-read text, and read-aloud capabilities. By facilitating clearer communication, CardMedic aims to improve the quality of care and reduce health inequalities, ensuring that patients can access essential healthcare information in a way that is understandable to them. The platform is accessible via smartphones, tablets, or desktops, making it a versatile tool for both patients and healthcare providers.

HeyRenee is the personal health concierge, everyone, especially those managing chronic illnesses and conditions, has wanted and needed. The patient-centric HeyRenee platform is designed to consolidate, coordinate, communicate and connect all aspects of medical care. Through long-sought data integration with healthcare providers, the platform endeavors to eventually help all Americans, the underserved especially, connect with their entire healthcare team and relieve the burdens of appointment scheduling, in-home visits, prescription medication administration to Telehealth and remote patient monitoring, and more

Canopie is a digital platform focused on addressing maternal depression and anxiety through customized, audio-based programs and automated coaching. By utilizing clinically validated therapeutic techniques, including adaptations of cognitive behavioral therapy and compassion-focused treatment, Canopie aims to prevent and manage maternal mental health disorders effectively. The platform collaborates with cities, payers, health systems, and healthcare providers to deliver accessible and affordable care for mothers, addressing significant barriers such as cost, scheduling, time constraints, and stigma associated with seeking help. Through its innovative approach, Canopie is dedicated to supporting pregnant women and new mothers in overcoming common mental health challenges.

Oculogenex is a biopharmaceutical company based in La Habra, California, established in 2020. The company specializes in developing gene therapies specifically aimed at treating retinal disorders. Its innovative approach involves ocular regenerative gene therapy that protects retinal pigment epithelial cells from oxidative stress-induced damage, which is a contributing factor to macular degeneration. By focusing on these therapies, Oculogenex aims to enhance the detection and treatment of various retinal disorders, ultimately supporting researchers in advancing novel drug solutions in this critical area of healthcare.

CardMedic is a healthcare platform designed to enhance communication between healthcare staff and patients, addressing various barriers such as language differences, visual and hearing impairments, cognitive challenges, and literacy issues. The platform features a comprehensive library of digital flashcards that replicate clinical conversations on common healthcare topics. These flashcards are available in multiple formats, including multilingual options, sign language, easy-to-read text, and read-aloud capabilities. By facilitating clearer communication, CardMedic aims to improve the quality of care and reduce health inequalities, ensuring that patients can access essential healthcare information in a way that is understandable to them. The platform is accessible via smartphones, tablets, or desktops, making it a versatile tool for both patients and healthcare providers.

MediCircle utilizes technology to eliminate barriers to care and reduce pharmaceutical waste. The company collects leftover oral chemotherapeutics, ensures the medicine’s quality, and redistributes it to those in need. Its advanced technology allows them to offer a safe, low-cost alternative to disposal. MediCircle creates significant savings for patients, insurance companies, and healthcare facilities, all while improving the health of its local communities.

Vaccine Systems expedites and simplifies vaccine preparation for caregivers and patients. Millions more people, particularly in the developing countries, can be immunized, saving tens of thousands of labor years through worldwide vaccination campaigns. Vaccine Systems creates equipment to help with this, resulting in increased access to vaccines, simplified preparation, and an essential margin of safety for those prepared at the point of care. At the same time, we reduce vaccine waste – which the WHO claims varies from 30% to 70% – and suboptimal vaccine re-allocation.

MyoGene Bio develops therapies for muscle diseases, starting with a gene-editing therapy for Duchenne muscular dystrophy.

SafetySit is a company focused on creating assistive therapeutic devices aimed at supporting disabled or recovering patients who struggle to maintain an upright sitting position due to insufficient core muscle strength. The company has developed a mobile backrest designed to aid clinicians in treating these patients, facilitating the early mobilization process essential for recovery. This innovative product reduces the need for clinicians to provide manual support, thereby enhancing the efficiency of therapy sessions and improving overall patient outcomes. By prioritizing user comfort and clinical effectiveness, SafetySit aims to advance rehabilitation practices and support the recovery journey for individuals with mobility challenges.

Pal develops innovative solutions for the ASD community. It is to help families find the pal to empower their buds and neurodiverse children.

Selmod provides development of innovative small molecule therapies for the treatment of life-threatening invasive fungal infections.

Netnoids Rx Laboratories operates a cancer contract research organization that uses patient-derived organoid model systems to help find a cure for rare cancers.

INIA Biosciences utilizes the power of sound waves to develop non-invasive, home-administered, and closed-loop medical devices to manage chronic inflammatory diseases.

Opsin Biotherapeutics develops a pipeline of opsin-based gene therapies for pain management.

Thermy is a healthcare company focused on early breast cancer detection through a non-invasive screening tool that utilizes machine learning and thermography. The platform is designed to operate on both mobile and desktop devices, allowing for accessible screening options. By employing infrared cameras, Thermy aims to assist healthcare professionals in distinguishing patients with a high or low likelihood of breast cancer. This innovative approach seeks to reduce mortality rates associated with late detection, ultimately enhancing patient outcomes in breast cancer diagnosis.

ModoScript develops a B2B hardware SaaS solution aimed at enhancing remote treatment monitoring through big data analytics. The company focuses on high-price specialty pharmaceuticals, particularly Oral Oncolytics, to improve treatment outcomes by collecting and analyzing health data. This approach allows for the development of more personalized and safer therapies while facilitating better at-home care. ModoScript targets pharmaceutical companies, health insurance providers, and physician groups, and partners with mail-order specialty pharmacies and in-office pharmacies for distribution. The company's mission is to provide a customizable data analytics model that improves patient outcomes and enables access to its solutions at no cost for patients. By prioritizing chronic disease patients, ModoScript aims to ensure high-quality remote care that is equitable, regardless of race, condition, or socioeconomic status.

Developer of material technologies intended to provide virus and bacteria protection for up to several months. The company's core nanotechnology is as safe as water for human contact yet works against some of the most concerning germs, such as MRSA, and norovirus, enabling users to reduce the infections from surfaces while also reducing chemical release and plastic waste to the planet.

Uniphage is a biotech company that eliminates bacterial infections by combining the power of bacteriophages with artificial intelligence. Their first target disease is citrus greening, an incurable and debilitating disease that costs the United States more than $2 billion each year. Uniphage created the first commercially effective models for computationally predicting safe bacterial viruses against target bacterial infections, as well as discovered a variety of targets. This enables them to deliver new antimicrobial, safe, and precise products to market much more quickly.

NurLabs develops label-free and reagent-free diagnostics to detect cancer early when it is most treatable.

Transcera is a biotechnology company focused on advancing the treatment of chronic diseases through innovative drug delivery systems. It has developed a novel lipid-based platform that enhances the targeting and absorption of therapeutic molecules, allowing larger drugs to effectively cross cellular barriers. This approach aims to improve the pharmacokinetics of treatments, ultimately benefiting patient outcomes by ensuring that medications are delivered more precisely and efficiently. Transcera's technology represents a significant advancement in drug delivery, addressing critical challenges in the management of chronic conditions.

Akttyva Therapeutics focuses on developing targeted therapeutics aimed at addressing cell barrier dysfunction, particularly in vascular barrier disorders. The company leverages its understanding of biological pathways, along with artificial intelligence and machine learning, to design innovative treatments. By concentrating on the structural aspects of cell barriers, Akttyva Therapeutics aims to provide solutions that enable healthcare professionals to effectively manage various medical conditions related to cell barrier dysfunction.

Asan Therapeutics utilizes a novel technology that simplifies the treatment of cancer patients to receive only a single injection instead of several painful injections.

FormaPath, founded in 2015 and based in Ithaca, New York, specializes in the development of the Adipress, an automated device designed to enhance the efficiency of tissue preparation for cancer diagnosis. In the United States, pathology labs process approximately 75 million tissue samples annually, often relying on manual methods that can lead to missed critical diagnostic tissue and misdiagnoses, particularly in colorectal cancer cases. The Adipress addresses this issue by allowing clinicians to prepare complete cancer samples in just 60 seconds, significantly reducing the time compared to traditional methods, which can take up to an hour. Registered with the FDA as a class 1 medical device, the Adipress is supported by two issued US patents and a pending PCT application in Europe. This innovative technology enables clinicians to submit all available tissue for diagnosis, ultimately improving diagnostic accuracy and patient outcomes.

AcousticaBio is a biotechnology company focused on reformulating intravenous medications for subcutaneous delivery. The company has developed a fluid processing technology that creates complex microparticles, enabling the conversion of biologic products typically administered intravenously into highly concentrated, small-volume injections suitable for under-the-skin administration. This innovative approach allows patients to self-administer essential medications with less pain and discomfort, reducing the need for lengthy hospital visits and enhancing overall patient convenience.

Imago Rehab offers a digital health solution for outpatient occupational therapy at home. It enables recovery for stroke survivors through home-use wearable robotics and digital health. It uses cutting-edge technology to help those with upper limb impairments restore arm function and live their most independent lives.

Glamorous AI is a developer of an artificial intelligence-based drug discovery platform. The company's platform specializes in the research of medicines from the preceding experimental results, identifies and assimilates multiple subtle and complex compounds.

NERAMCO develops smart polyethylene fibers and fabrics, SVETEX, for the textile industry. SVETEX materials have superior functionality and can be used as a sustainable/recyclable material that reduces water consumption and pollutants. The company develops apparel for children with skin disorders, and temperature-reducing underwear for menopausal women (for comfort) and all men (for improved fertility).

Developer of a medical therapeutic device designed to provide an alternative to invasive cardiac rhythm management. The company's platform provides neuromodulation therapies to address heart failure and cardiac arrhythmias by making use of the heart's transverse pericardial sinus, the device is minimally invasive and does not penetrate any blood vessels or require multiple leads to be implanted, enabling doctors to combine multiple leads into one and do multi-chamber pacing from outside.

Paragit Solutions is focused on improving the assessment of motor symptoms related to Parkinson's disease and enhancing the evaluation of new therapies. The company has developed a healthcare tracking device that employs artificial intelligence to monitor and quantify these symptoms. This device consists of a sleeve that records daily routine data, which is then stored in cloud storage. By enabling neurologists to access this data, Paragit facilitates more accurate treatment decisions for patients suffering from Parkinson's disease. This innovative approach aims to transform how patients are medicated and how their conditions are managed.

Aidplex is a MedTech startup focused on transforming the orthopedic sector through patient-centered products and advanced monitoring solutions. The company initially enters the market with splinting products, while also planning to diversify by redesigning back brace solutions. Aidplex develops wearable devices that enable real-time monitoring of patients' health and treatment progress, specifically for conditions such as scoliosis and fractures. By integrating IoT technologies with e-health services, Aidplex aims to empower patient monitoring and facilitate timely interventions by physicians, thereby enhancing efficiencies and improvements in the rehabilitation process. The company is committed to exploring innovative solutions within orthopedics in the future.

BrightCure Ltd. is a company based in London, United Kingdom, that specializes in developing probiotic-based therapies aimed at treating urinary tract infections (UTIs). Founded in 2019, BrightCure addresses the significant challenge of recurrent and difficult-to-treat UTIs, which affect a large portion of the global population, particularly women. Conventional UTI treatments often fall short in effectiveness and can lead to serious side effects, contributing to the rise of antibiotic-resistant infections. The company focuses on leveraging the natural microbiome to eliminate harmful bacteria while restoring beneficial flora. BrightCure's flagship product, a bioactive intimate cream, is designed to enhance the natural immune response and support urinary tract health. The UTI treatment market is projected to grow significantly, reflecting the urgent need for effective solutions. BrightCure has received recognition for its innovative approach, including seed investment from SOSV and accolades in various competitions, underscoring its potential impact in the healthcare sector.

BestHealth4U focuses on researching and developing advanced medical adhesive technologies aimed at enhancing patient care. The company creates innovative and eco-friendly adhesive solutions designed to prevent skin injuries, accelerate healing, and improve overall patient health. By transforming the attachment methods for bandages, dressings, and medical devices, BestHealth4U enables healthcare providers to minimize skin damage, discomfort, irritation, and the risk of infection. The company's commitment to safe and effective products supports doctors in preventing adhesive-related skin injuries, ultimately promoting better patient outcomes.

Epios personalized and precision management of brain disorders using daily life monitoring and therapeutics. The Epios system comprises a series of thin leads incorporating sensing electrodes and a miniature implant, inserted beneath the skin. The neural signals are wirelessly transmitted to an external receiver held in place on the skin directly over the implant with a magnet, and from there are conveyed to a wearable data processor and are finally securely stored in the Epios Cloud.

TrainPain is an early stage digital therapeutics company developing an innovative digital treatment for chronic neuropathic pain. Our low cost home based platform assesses and treats pain related neuroplasticity using a proprietary tactile stimulation device and sensory perception tasks embedded into captivating mobile video games.

ThermoTerra develops heating and cooling technology based on a novel source of renewable energy.

Tiktalk To Me owns and operates a digital health company intended to offer a platform for speech therapy. Its platform functions as a virtual speech therapist, guiding patients through proven and widely accepted training protocols using online games supervised by the patient's personal speech therapist and combines gaming with speech- and voice-recognition technology, enabling speech-language pathologists to shorten the treatment cycle and save substantial time and money for the patients.

Pacify Medical Technologies is a medical device startup with patent-protected technology that sprays skin tissue on wounds for fast recovery.

SANITAS operates a cloud-based telehealth platform that specializes in behavioral health and autism. Founded in 2019 and based in Los Angeles, California, the platform connects users directly with therapists and experts, facilitating access to essential mental health resources. By leveraging social media-styled tools within secure private networks, SANITAS creates a supportive environment that promotes peer engagement and shared experiences. The platform offers a range of tools for well-being, including mindfulness practices, cognitive behavioral therapy (CBT), coaching, and teletherapy, all designed to enhance the user experience. By addressing the physical, psychological, and social aspects of mental health, SANITAS aims to improve emotional and physical well-being for individuals seeking support.

UpLift Health Inc., based in Atlanta, Georgia, specializes in developing a digital application aimed at treating depression through cognitive behavioral therapy (CBT). The platform offers users a structured program consisting of twelve weekly sessions, each lasting approximately 40 minutes, where they learn effective coping skills. In addition to the sessions, users engage with daily tools that encourage the application of these skills in their daily lives. The program includes chatbot-guided interactions that provide feedback and guidance, fostering an interactive and supportive experience. A pilot study indicated a significant reduction in depression symptoms among participants, with UpLift's goal being to assist one million individuals in overcoming depression through its evidence-based approach.

PainPal is a behavioral health platform tailored for people with chronic pain, that provides personalized, gamified, and on-demand Cognitive Behavioral Therapy (CBT-CP) treatment and counseling, proven to reduce pain and increase functioning.

Digbi Health, LLC provides digital therapeutics services. It offers health programs, such as weight loss diets for skin and gut disorders, hypertension, elevated cholesterol, and diabetes. It also provides an online application to track 9-key metrics, such as stress, energy, and weight. The company is based in Mountain View, California with additional offices in Bengaluru, Karnataka and Taguig, Philippines.

SANITAS operates a cloud-based telehealth platform that specializes in behavioral health and autism. Founded in 2019 and based in Los Angeles, California, the platform connects users directly with therapists and experts, facilitating access to essential mental health resources. By leveraging social media-styled tools within secure private networks, SANITAS creates a supportive environment that promotes peer engagement and shared experiences. The platform offers a range of tools for well-being, including mindfulness practices, cognitive behavioral therapy (CBT), coaching, and teletherapy, all designed to enhance the user experience. By addressing the physical, psychological, and social aspects of mental health, SANITAS aims to improve emotional and physical well-being for individuals seeking support.

knowRX™is a mobile online application that schedules, monitors, and provides feedback on drug usage (prescription and over-the-counter medicines) for consumers and designated medical contacts. knowRX™ promotes wellness, accountability, and consumer feedback throughout the completion of a course of therapy. knowRX™ is designed to promote well-being through an online platform for patient and physician engagement. The Platform provides important drug information and current clinical trial reports to assist healthcare providers and their patients in the selection of the right therapy for the individual. Additionally, through this user-friendly app, patients are offered access to counseling, genomics data for treatment compatibility, nutritional guidance, holistic insights, clinical trial opportunities and instructional videos on clinical research, and trending analysis regarding medication behavior, all with the goal of achieving the most beneficial treatment outcomes. The makers at knowRX™ recognize that drug adherence is a major factor in the success of medical therapy. There is no single solution that addresses nonadherence for all patients. We set out to create an interactive platform that makes available multiple solutions and learns about consumers to establish and refine access to tools that best fit the respective needs of individual patients.

Augment Therapy, Inc. develops interactive augmented reality telemedicine software solution for pediatric physical therapy. The solution provides real-time and remote monitored session on physical therapy and automates data collection for therapists. Augment Therapy, Inc. was founded in 2017 and is based in Cleveland, Ohio.

Kinto.Care is a provider of an online platform intended to improve communication and provide practical advice for caregivers. The company's platform features user-generated content and digital tools to improve care team collaboration, medication management and check-in data tracking, enabling the family members of a patient to coordinate care and manage medicines through a single platform.

Developer of a chronic care management health platform designed to offer diabetes treatment via the virtual world. The company's platform uses a peer network and constructivist curriculum to improve wellness, enabling professionals and chronic disease patients to face high-intensity, high-stress environments to accelerate behavior change and optimize chronic disease outcomes.

Limula Biotech is a Swiss company specializing in the design and development of an automated system for manufacturing cell and gene therapies. The company has created a patented platform that enables the distributed production of genetically engineered cells directly at the patient's bedside, utilizing a patient's white blood cell sample. This fully closed bioreactor system minimizes human intervention during the manufacturing process while maintaining control over cell culture parameters. By facilitating on-site production in hospitals, Limula's technology aims to enhance the safety, accessibility, and efficiency of personalized gene therapies, ultimately reducing time, costs, and logistical challenges. Founded in 2018 and based in Lausanne, Switzerland, Limula Biotech is committed to revolutionizing the delivery of ex vivo gene-engineered cell therapies.

Healium is a drugless solution for the self-management of anxiety. It's the world's first immersive media channel powered by the user's brainwaves and heart rate via their wearables. In three peer-reviewed journals, Healium has been shown to quickly reduce anxiety and increase feelings of positivity in as little as four minutes. These data-driven VR and AR escapes are controlled by the user's emotions displayed on the screen via their wearables.

Developer of nanotechnology intended to solve challenges across medicine and other industries. The company uses different types of biomaterials as building blocks and has fabricated diverse types of systems such as nanoengineered hydrogels, nanosized molecular delivery systems, and nanocomposite materials, helping businesses across different industries to use nanotechnology and grow their business.

Path Ex, Inc. is a Nashville-based company that specializes in manufacturing extracorporeal blood cleansing equipment. Established in 2017, Path Ex has developed a proprietary technology designed to selectively separate and capture bacteria and toxins from human blood, specifically for the treatment of sepsis, a critical condition often resulting from blood-borne infections. This innovative approach focuses on removing intact bacteria from the bloodstream instead of relying on broad-spectrum antibiotics, making it effective against various bacteria types and drug-resistant strains. The technology aims to improve patient outcomes by reducing diagnostic times, lowering treatment costs, decreasing readmission rates, and ultimately decreasing sepsis-related fatalities.

Microbial Pulse Diagnostics is developing and deploying an innovative NIST technology for the rapid measurement of antimicrobial susceptibility. This technology “takes the pulse” of bacterial cells, sensing changes in their metabolism, motility, and growth after exposure to an effective antibiotic.

NeuroRescue Inc. develops and manufactures cervical collars that facilitate therapeutic hypothermia. It offers NeuroRescue SC3, a product that enables emergency medical technicians to non-invasively initiate therapeutic hypothermia in field with off the shelf cold packs while transitioning at the hospital to controlled and monitored continuous flow cooling throughout definitive care for post-cardiac arrest with return of spontaneous circulation. The company’s product is used for stroke, post cardiac, and head injury. NeuroRescue Inc. was founded in 2010 and is headquartered in Lafayette, Louisiana.

OrganoTherapeutics is a company focused on developing medical drugs aimed at treating Parkinson's disease. It utilizes advanced human-specific mini-brain models that accurately replicate the pathology of Parkinson's disease for the discovery and development of effective drug candidates. By employing three-dimensional models derived from both healthy individuals and patients with Parkinson's disease, OrganoTherapeutics identifies the therapeutic potential of various compounds and analyzes data using artificial intelligence. This innovative approach facilitates the screening of new molecules, allowing researchers to advance novel drug candidates. The company has already developed proprietary drug candidates and has access to extensive libraries for further research and development.

Articulate Labs, Inc. is a medical device company based in Austin, Texas, founded in 2009. The company specializes in developing wearable devices aimed at treating knee osteoarthritis. Its flagship product, KneeStim, employs neuromuscular electrical stimulation (NMES) to enhance the rehabilitation of knee function by stimulating quadriceps muscles during daily activities. By integrating electrical muscle stimulation into routine movements, Articulate Labs' devices address muscle atrophy and inhibition associated with chronic conditions or surgical recovery, making physical rehabilitation more accessible and effective for patients.

Medical Elution Devices features polymer-coated devices containing medication(s) that is engineered to adhere to the surface of existing chest tubes, endotracheal tubes, implants, etc., and elute drug over a pre-determined period.

O2 RegenTech LLC is commercializing cost-effective, easy-to-use wound care solutions. Our proprietary, patented technology is used in our initial product offering, OXAID™, as an oxygenating, moist, and antimicrobial dressing to promote and accelerate chronic wound healing.

Developer of respiratory devices designed to administer medication in the form of inhalation into the lungs. The company specializes in designing and manufacturing nebulizers that are used for the treatment of asthma, cystic fibrosis, and other respiratory diseases or disorders as well as the product avoids medication errors and does not require cleaning or disinfection, enabling the medical community and patients to optimize treatment outcomes and overall quality of life that use nebulizers.

Noleus Technologies Inc., based in Houston, Texas, focuses on developing a medical device aimed at enhancing patient recovery after abdominal surgery. The company's product is designed to prevent intestinal wall edema and postoperative ileus, conditions that can lead to prolonged hospital stays and increased healthcare costs. By addressing these issues, Noleus's device facilitates a quicker return of bowel function, thereby enabling patients to recover sooner and reducing the complications that typically extend hospital stays. This innovation not only benefits patients but also helps healthcare providers save time and reduce costs associated with extended care.

MIBIOMICS mission is to develop innovative, safe, and effective microbiome-based solutions to treat currently incurable skin diseases.

Adiposs Sàrl is a Swiss biotech start-up focused on developing medical imaging products and technologies for the early detection of cachexia, a severe body-wasting syndrome characterized by weight loss, muscle atrophy, fatigue, weakness, and loss of appetite. Founded in 2020 and based in Plan-les-Ouates, Switzerland, the company has created ImageBAT, a CT contrast agent that facilitates the early identification of cachexia, potentially one year before noticeable weight loss occurs. This capability allows hospitals and healthcare providers to detect underlying conditions, such as cancer, at an earlier stage, thereby improving patient quality of life and increasing their chances of survival in the face of chronic diseases.

ChondroNest is focused on developing medical technologies aimed at cartilage reconstruction, specifically targeting conditions such as Osteochondritis and Osteoarthrosis. The company is creating a device made from modified biopolymers intended for in vivo use, facilitating easier and more effective reconstruction surgeries for surgeons. ChondroNest plans to conduct preclinical tests on animal models before moving on to human trials. Following these initial trials, the company intends to license its product to major MedTech companies for sales and marketing purposes, while maintaining control over the production of its ChondroNest™ pastes.

Karuna Health, Inc. is a company that develops a platform aimed at automating patient care management tasks for hospitals. Founded in 2018 and headquartered in San Francisco, California, its platform facilitates communication between patients and care managers, reminding patients of appointments and collecting health status information. The integrated solution provides a single platform that helps manage interactions among patients, family members, and healthcare teams. It includes tools for scheduling appointments, organizing transportation, and delivering automated reminders, all while ensuring compliance with healthcare regulations. Karuna Health's goal is to enhance patient access to healthcare guidance and support throughout their care journey.

Sano Chemicals is an early stage biotechnology company primarily focused on the development of novel anti-infectives for clinical and agricultural use. The word “Sano” is derived from the Latin word meaning health, thus, they are focused on the development of products that will promote their health and a healthy and sustainable environment. Sano Chemicals is focusing on the development of antifungal treatment options for fungal infections and antifungal bio-control methods for crops. Their goal is to innovate the anti-fungal industry. The antifungal occidiofungin is a completely unique antifungal compound discovered by researchers at Mississippi State University and Texas A&M University. Novel applications in occidiofungin's use are being developed through the innovative endeavors of their scientists. Products that cure fungal infections (nail, skin, and systemic), as well as products that promote a sustainable food supply by targeting fungal diseases in plants are being developed.

Developer of drug delivery solutions intended to facilitate enhanced absorption of co-administered therapies. The company offers novel drug delivery solutions built around its proprietary permeation enhancer, being able to replace current intravitreal injections of biologics with eye drops, enabling users to get patient safety, patient compliance, and decreased health care costs.

Solenic Medical, Inc. is a medical device company founded in 2019 and based in College Station, Texas. It specializes in developing a non-invasive treatment for infected metallic implants using a technology that employs alternating magnetic fields generated by external coils. This innovative approach targets biofilm on the surfaces of medical implants, which is a significant complication in surgeries like knee and hip replacements, as well as in trauma-related procedures involving plates and rods. The technology has the potential to replace the costly and risky two-step revision surgical procedure currently used to address chronic infections in medical implants, thereby offering a safer and more effective solution for patients.

Syntr Health Technologies is a start-up company that develops and tests a processing device, SyntrFuge™, for the micro fragmentation of adipose tissue for body contouring. Ahmed Zobi, Hugo Salas, and Justin Stovner established the Irvine, California-based company in 2019.

TomoWave is a company focused on developing innovative imaging technologies for clinical medicine and preclinical research. Utilizing its proprietary optoacoustic and laser ultrasonic imaging modalities, TomoWave aims to enhance cancer detection, guide medical interventions, and monitor the effectiveness of cancer therapies. The company's technology, which captures images by "listening to the sound of light," allows for highly detailed visualization of tissues, particularly in relation to vascular and blood-related conditions. Founded by Dr. Alexander Oraevsky, a pioneer in biomedical optoacoustics, TomoWave has a strong emphasis on generating intellectual property and advancing it from concept to validated clinical prototypes. The company is committed to bringing its technologies to market through appropriate regulatory certifications, thus contributing to improved diagnostic capabilities in healthcare.

Octarine Bio is a biotechnology company based in Copenhagen, Denmark, founded in 2018. The company specializes in the research and development of cannabinoid and psilocybin derivatives using synthetic biology. By employing a biosynthetic platform, Octarine Bio aims to create a range of natural and novel cannabinoid and psilocybin-derived molecules that possess enhanced pharmacokinetic and therapeutic properties. These advancements are designed to support healthcare professionals in treating neurological and psychological disorders, ultimately improving the health and well-being of individuals.

Eleos Health is a company that develops a software-as-a-service (SaaS) tool focused on mental health. Utilizing artificial intelligence and voice technology, Eleos Health's platform operates in the background during mental health sessions to gather insights into a patient's behavioral health. By analyzing voice interactions and various data parameters, the tool provides valuable information that enables clinicians to deliver personalized care and support tailored to individual patient needs.

Tzofen is a biotechnology company focused on developing a novel biological platform aimed at treating various types of cancer. This innovative platform has demonstrated the ability to eliminate cancer growth both in vitro and in vivo, highlighting its potential to significantly impact cancer treatment. By advancing this technology, Tzofen seeks to contribute to saving millions of lives affected by cancer.

Developer of a practice management platform designed to streamline administrative tasks and deliver therapy sessions. The company's platform allows to enter and manage patient information, including demographics, contact details, and treatment history, send assessment forms to parents electronically through the system, schedule appointments, and track progress, enabling doctors and parents to facilitate communication leading to better outcomes for children with speech and communication disorders.

Thinks Works is an early-stage biomedical company developing ideas and products that help to solve problems that humans are dealing with. It is the concept of founder Ryan C. Murdock, MD. Through his interactions with his patients dealing with the condition of scoliosis, he saw a need for improvement in the treatment of scoliosis. He set this as a goal and now has begun to build an incredible team to bring his vision to reality so that we may dramatically improve the lives of these patients. Its device is for the non-operative treatment of adolescent scoliosis, a severe curvature of the spine in kids. Approximately 10,000 US kids per year require brace treatment. The current treatment is a custom-made hard plastic brace. It keeps the spine immobile by compressing the ribs. It has poor patient compliance and outcomes at a high patient cost. Its novel device will improve patient comfort, compliance, and outcomes at a lower total patient cost.

Hera - Mi is Specialized in digital medical imaging applied to breast cancer.Hera-MI has developed clinical decision support solutions to help improve early-stage breast cancer detection. Our solutions will improve the quality and accuracy of breast cancer diagnosis while decreasing radiologists’ interpretation time. Patients will be treated more quickly, offering them a better chance of remission. Hera-MI has developed Breast-SlimView, a clinical decision support software based on artificial intelligence and image processing for breast cancer diagnosis. Our partner, Fujifilm is selling Breast-SlimView in France and in the Overseas Territories of France (DROM/TOM). Breast-SlimView is also available for sale all over the world.

Relavo, LLC is a medical device company founded in 2018 and based in Baltimore, Maryland. The company focuses on developing solutions to prevent infection related to peritoneal dialysis, specifically through its product, The PeritoneX. This device disinfects contamination points prior to the initiation of dialysis treatment, thereby helping patients with kidney failure to lower their risk of developing peritonitis. By offering an affordable means to enhance safety during peritoneal dialysis, Relavo aims to improve patient outcomes in this critical area of healthcare.

Relavo, LLC is a medical device company founded in 2018 and based in Baltimore, Maryland. The company focuses on developing solutions to prevent infection related to peritoneal dialysis, specifically through its product, The PeritoneX. This device disinfects contamination points prior to the initiation of dialysis treatment, thereby helping patients with kidney failure to lower their risk of developing peritonitis. By offering an affordable means to enhance safety during peritoneal dialysis, Relavo aims to improve patient outcomes in this critical area of healthcare.

Developer of nanotechnology intended to solve challenges across medicine and other industries. The company uses different types of biomaterials as building blocks and has fabricated diverse types of systems such as nanoengineered hydrogels, nanosized molecular delivery systems, and nanocomposite materials, helping businesses across different industries to use nanotechnology and grow their business.

Articulate Labs, Inc. is a medical device company based in Austin, Texas, founded in 2009. The company specializes in developing wearable devices aimed at treating knee osteoarthritis. Its flagship product, KneeStim, employs neuromuscular electrical stimulation (NMES) to enhance the rehabilitation of knee function by stimulating quadriceps muscles during daily activities. By integrating electrical muscle stimulation into routine movements, Articulate Labs' devices address muscle atrophy and inhibition associated with chronic conditions or surgical recovery, making physical rehabilitation more accessible and effective for patients.

InvivoSciences specializes in phenotypic compound screening services that enhance drug discovery and repositioning. The company employs an innovative approach that combines tissue engineering technology with assay automation and sample miniaturization, facilitating rapid and cost-effective therapeutic discovery. Its mission focuses on developing engineered tissue-based assays that closely replicate the functions of living organisms, including humans and animals. By integrating patient-derived and gene-edited human samples, InvivoSciences aims to personalize the drug development process. The company utilizes advanced techniques in cell and tissue handling, tissue phenotyping assays, and computational biology, including artificial intelligence, to assist clinicians in swiftly identifying the safety and efficacy of treatments tailored to specific patient groups, thereby optimizing the preclinical phase before embarking on costly clinical trials.

Tellus Therapeutics is a biopharmaceutical company focused on creating innovative treatments for newborns facing perinatal brain injuries. The company specializes in developing small molecules derived from human maternal breast milk, which aim to promote the regeneration of myelin-producing oligodendrocytes and mitigate white matter injury in premature infants. By addressing unmet medical needs, Tellus Therapeutics enables healthcare providers to offer effective interventions for all babies at risk of brain injury, thereby improving neurodevelopmental outcomes for these vulnerable children.

Developer of implantable neuromodulation systems designed to effectively and safely treat patients with pelvic health conditions. The company's technology modulates distal target nerves locally by stimulating only the target and can be used to modulate innervation to muscles or organs alike, enabling patients to avail less invasive, safer, and more effective therapy for conditions like incontinence, sexual dysfunction, and chronic pain.

Developer of an antibody drug discovery platform designed to reprogram cancer cells to treat advanced cancers to be centered around proprietary artificial intelligence. The company's platform designs custom antibodies with high selectivity and specificity linked to proprietary cellular reprogramming lab assays, its drugs modulate activities of a novel set of growth factors called dual smad inhibiting protein dips, thought to drive the growth and spread of cancer, enabling physicians to get access to novel drugs in areas of unmet medical needs.

Developer of medical test kits designed to detect infections remotely. The company offers an on-the-spot saliva test kit using convenient sensitivity protein detection technology that identifies whether the user has an active infection or not, enabling people to understand and make informed decisions about their bodies and health.

Mantle Biotech engineers binding proteins that can accurately identify disease biomarkers in patient samples, using directed evolution to modify heat-stable proteins produced by microbes. It allows the company to develop new diagnostic capabilities, producing high-quality binding proteins that are more stable and affordable than traditional reagents. This reagents can be adapted to a range of diseases and test formats, allowing the team to identify pain points throughout the broader diagnostic industry. Mantle Biotech was founded on 2019 and is headquartered in Cambridge, Massachusetts.

Clara Biotech is focused on developing a platform technology for the isolation and purification of exosomes from small fluid samples, facilitating liquid biopsies for early detection of various diseases, including cancer and Alzheimer's Disease. Unlike traditional methods that require lengthy ultra-centrifugation, Clara's platform can extract pure and viable exosomes from any biofluid source efficiently. This innovative process enhances the potential for precision medicine by enabling targeted drug delivery directly to specific cells. Additionally, Clara Biotech's technology supports the development of unique liquid biopsy assays, improving the accuracy of disease detection and addressing challenges faced by biopharma companies in the medical field. Overall, Clara Biotech aims to advance research into clinical applications, bridging the gap between laboratory findings and patient care through its exosome-based solutions.

Adaptilens, LLC is focused on developing an innovative injectable intraocular lens designed to provide patients with clear near and distance vision without the need for eyeglasses or contact lenses. This accommodating lens mimics the natural lens of the eye, allowing the ciliary muscles to change its shape for optimal focus at varying distances. By returning to its baseline elliptical shape, the lens facilitates clear vision for distant objects when needed. Founded in 2019 and based in Chestnut Hill, Massachusetts, Adaptilens aims to enhance the quality of vision for individuals, promoting a more natural visual experience.

Developer of molecular technology intended to discover and deliver beneficial bacteria. The company's technology facilitates the production of next-generation probiotics, enabling clients to improve the wellness of humans and animals.

Aniluxx Biotechnology is a development stage biopharmaceutical company with a mission to improve companion animal health and well-being. The Company’s strategy is to translate its deep pipeline of topically formulated therapeutics, predicated on compounds that have already been identified as safe and effective in humans, into therapies for dogs, cats, and horses, that are easy to apply, virtually unnoticeable, and absent the harsh side effects of systemic medicines.

MIBIOMICS mission is to develop innovative, safe, and effective microbiome-based solutions to treat currently incurable skin diseases.

Virtual is a developer of prescription digital therapeutics platform intended to help mental health treatment. The company's tool adheres to strict compliance with FDA quality management standards and also is put through rigorous research trials and in certain cases is paired with existing pharmacological treatments, as well as uses virtual reality to administer VR exposure therapy, assign CBT assessments or exercises and track patient progress, enabling patients to overcome anxiety, phobia and obsessive-compulsive disorder easily.

Virtual is a developer of prescription digital therapeutics platform intended to help mental health treatment. The company's tool adheres to strict compliance with FDA quality management standards and also is put through rigorous research trials and in certain cases is paired with existing pharmacological treatments, as well as uses virtual reality to administer VR exposure therapy, assign CBT assessments or exercises and track patient progress, enabling patients to overcome anxiety, phobia and obsessive-compulsive disorder easily.

DynamiCare Health, Inc. provides a digital platform that helps people to monitor and reduce the use of drugs, opioids, alcohol, and tobacco. Its platform allows people to perform substance tests through an application; and tracks treatment attendance using GPS. The company also allows healthcare providers to see data about participant’s progress through the DynamicCare Analytics portal, which sends real time risk alerts when clients are in trouble. DynamiCare Health, Inc. was founded in 2016 and is based in Boston, Massachusetts.

Eleos Health is a company that develops a software-as-a-service (SaaS) tool focused on mental health. Utilizing artificial intelligence and voice technology, Eleos Health's platform operates in the background during mental health sessions to gather insights into a patient's behavioral health. By analyzing voice interactions and various data parameters, the tool provides valuable information that enables clinicians to deliver personalized care and support tailored to individual patient needs.

DynamiCare Health, Inc. provides a digital platform that helps people to monitor and reduce the use of drugs, opioids, alcohol, and tobacco. Its platform allows people to perform substance tests through an application; and tracks treatment attendance using GPS. The company also allows healthcare providers to see data about participant’s progress through the DynamicCare Analytics portal, which sends real time risk alerts when clients are in trouble. DynamiCare Health, Inc. was founded in 2016 and is based in Boston, Massachusetts.

Karuna Health, Inc. is a company that develops a platform aimed at automating patient care management tasks for hospitals. Founded in 2018 and headquartered in San Francisco, California, its platform facilitates communication between patients and care managers, reminding patients of appointments and collecting health status information. The integrated solution provides a single platform that helps manage interactions among patients, family members, and healthcare teams. It includes tools for scheduling appointments, organizing transportation, and delivering automated reminders, all while ensuring compliance with healthcare regulations. Karuna Health's goal is to enhance patient access to healthcare guidance and support throughout their care journey.

Artiria Medical SA develops micro-actuated device to treat vascular diseases. Its products bring micromotion deep in the brain arteries, enabling a navigation and stroke treatment. It empowers catheters and guidewires. Artiria Medical SA was incorporated in 2019 and is based in Lausanne, Switzerland.

Medical company specialized in non invasive brain stimulation technologies for the treatment of neurological diseases.