MassChallenge

TrainPain is an early stage digital therapeutics company developing an innovative digital treatment for chronic neuropathic pain. Our low cost home based platform assesses and treats pain related neuroplasticity using a proprietary tactile stimulation device and sensory perception tasks embedded into captivating mobile video games.

Manetu, Inc. develops a consumer privacy management (CPMSM) platform. It offers The Manetu CPMSM, a platform that acts as an infrastructure for the end-to-end management of the private information to provide the service to the users’ customers. The company’s platform is also used for collaborating with the customers to manage all their sensitive data; enables users’ customers to determine what data they will share and for how long. Manetu, Inc. was incorporated in 2019 and is based in Ridgewood, New Jersey.

Muxy, Inc. is a company based in Austin, Texas, that specializes in developing software for live streaming platforms, particularly Twitch. Founded in 2015, Muxy offers a range of tools designed to enhance the experience of live broadcasters and their audiences. Their products include interactive live video applications, the Muxy Extension Development Kit for Twitch extension development, and Muxy Alerts, which provide real-time notifications for followers, donations, subscriptions, and other interactions. Additionally, Muxy provides analytics services for brands, along with a programmatic ad network tailored for Twitch. Their tools also include features like the Muxy Cheer Cup and Cheer Progress Bar, which significantly boost engagement on the platform. The company's ongoing development efforts aim to create more innovative engagement solutions for brands, influencers, and developers.

TrucksOnTheMap Limited is a company that has developed a digital freight brokerage platform designed to enhance truck and freight management services. Established in 2015 and headquartered in London, the company offers a software as a service (SaaS) platform that provides features such as truckload allocation, bidding, process analysis, job allotment, and truck tracking. The platform specializes in providing a comprehensive visualization of truck availability, enabling trucking professionals to view a map of both owned and partner-free trucks. This functionality allows users to request quotations for available trucks near loading addresses, effectively turning empty freight runs into profitable opportunities.

Medical Simulation Technologies is a startup company, established for the commercialization of advanced medical simulators, especially in the field of cardiology. The technology that we provide results from many years of research. The key to our success is an open mind and a team of professionals, which is why our company is composed of a multidisciplinary group of experts: programmers, hardware specialists and medical professionals. We do believe that this gives us advantage in innovation, quality, and a focus on practical solutions. Heart failure, or generally cardiovascular disease is still the leading cause of death. Overall quality of examination, proper diagnosis and difficult surgery success rate could be greatly improved, if the specialists had the opportunity of practical training using a faithful simulation platform. In opposite to every other simulator presents in the market, MST has developed the simulation platform based on a realistic heart model from Computed Tomography (CT). Thanks to that, a user can practice on artificial patient and can have the feeling of real examination or surgery.

Mi Terro is the world's first advanced material company that creates ocean degradable and home compostable flexible packaging materials made from agricultural waste. We are not turning agricultural waste into beverage or snack like other companies. Instead, we are giving agricultural waste a new life by repurposing it to replace plastic and paper-based materials and giving additional incomes to farmers all around the world. Our material accommodates a diverse range of fully compostable packaging applications for fresh produce, dry food, fashion, cleaning product, and standard product packaging. Our technology can potentially apply to any type of agricultural byproducts and surplus food, including plant, dairy, and vitamin supplement byproducts. Our process uses less energy than paper and plastic production while creating 90% less CO2 than plastic. We are replacing petroleum-based materials with protein-based materials made from agricultural waste. We are redefining the circular economy in which everything begins with agricultural waste and ends as compostable or biodegradable. We are taking a world problem and making it into a world solution. Our technologies will have more impact to the world than plant-based and cultivated meat.

Tellus Therapeutics is a biopharmaceutical company focused on creating innovative treatments for newborns facing perinatal brain injuries. The company specializes in developing small molecules derived from human maternal breast milk, which aim to promote the regeneration of myelin-producing oligodendrocytes and mitigate white matter injury in premature infants. By addressing unmet medical needs, Tellus Therapeutics enables healthcare providers to offer effective interventions for all babies at risk of brain injury, thereby improving neurodevelopmental outcomes for these vulnerable children.

Tellus Therapeutics is a biopharmaceutical company focused on creating innovative treatments for newborns facing perinatal brain injuries. The company specializes in developing small molecules derived from human maternal breast milk, which aim to promote the regeneration of myelin-producing oligodendrocytes and mitigate white matter injury in premature infants. By addressing unmet medical needs, Tellus Therapeutics enables healthcare providers to offer effective interventions for all babies at risk of brain injury, thereby improving neurodevelopmental outcomes for these vulnerable children.

MuukTest is a software testing platform powered by AI that increases Software Devs testing productivity up to 26X. The company was founded in 2019 and based in Raleigh, North Carolina.

Tacit Motion specializes in kinetic monitoring and personal training through the use of innovative wearable sensors. The company's modular and scalable system enables real-time full-body tracking, allowing users to receive personalized training anytime and anywhere. By capturing and analyzing body language, Tacit Motion’s technology provides a unique medium for communication that transcends traditional print or video formats. The recordings created by their system can be copyrighted, licensed, and shared, offering additional value to users. This approach empowers individuals and fitness enthusiasts to leverage their natural abilities to enhance their fitness journey, fostering progress through tailored activities and schedules.

MTTech Interactive Multimedia Systems Ltd develops multi touch display system in Israel. The system can use for product demonstration, research and development purpose, training, and team meeting. MTTech Interactive Multimedia Systems Ltd is headquartered in Tel-Aviv, Israel with additional offices in Burcharest, Romania; Holmdel, New Jersey; and Alamos, Mexico.

ReachMore application that treats anxiety created by trauma events.

TRAXX includes a robust, FCC/CE certified tracking device, per-configured right off the box to work worldwide (except Korea and Japan - sorry), a great-looking app (iOS and Android) and a 2 years global data plan. It is easily mounted on every motorcycle type and can be used anywhere, you can even cross boarders with it at no extra cost.

Tacit Motion specializes in kinetic monitoring and personal training through the use of innovative wearable sensors. The company's modular and scalable system enables real-time full-body tracking, allowing users to receive personalized training anytime and anywhere. By capturing and analyzing body language, Tacit Motion’s technology provides a unique medium for communication that transcends traditional print or video formats. The recordings created by their system can be copyrighted, licensed, and shared, offering additional value to users. This approach empowers individuals and fitness enthusiasts to leverage their natural abilities to enhance their fitness journey, fostering progress through tailored activities and schedules.

TAA produces technologies that validate the experiences of sexual assault survivors during the reporting process. TAA believes that scientific innovation can help to eliminate sexual assault. For the first time, TAA is integrating rapid evidence-validating tech into kits so that survivors leave the hospital knowing exactly what evidence has been collected and how it will be used in forensic labs. Alongside survivors, hospitals, advocates, and law enforcement, TAA is developing the next generation of rape kits to ensure that all survivors feel validated and in control of their evidence collection kit.

TFC Simulations is a Swiss company active in the manufacture of high quality simulators for the automotive, aviation and construction industries.

PRAGMA Therapeutics is a French leading neuroscience biotech company discovering and developing proprietary small molecule therapeutics for the treatment of stress-related diseases, in particular Post-Traumatic Stress Disorders (PTSD), and hearing loss. Founded in 2015, PRAGMA is a flexible organization led by a team with a world-leading experience in neuroscience drug development, targeting a specific class of G-protein-coupled receptors (GPCR), the metabotropic glutamate receptors family (mGluRs). PRAGMA currently develops allosteric modulators of the mGlu7 subtype which corresponds to a unique and innovative approach to regulate stress-related responses, fear and cognitive dysfunctions associated to PTSD, as well as acute and acoustic trauma-induced hearing loss. PRAGMA has integrated the new standards of drug development and aims at rapidly correlating in vivo proof-of-concept studies with target engagement and pharmacodynamic biomarkers in human in order to increase its success rate in clinical trials.

MPMsim is a developer of advanced simulation software tailored for the gaming and movie industries. The company has created a unique meshless structural analysis tool that addresses the limitations and inefficiencies commonly found in competing solutions. By utilizing a hybrid Lagrangian-Eulerian non-linear explicit dynamics solver, MPMsim's software allows clients to produce realistic animations and special effects with greater ease. The platform significantly simplifies the workflow by eliminating the need for labor-intensive tasks such as meshing and CAD de-featuring, which are typically required in design processes. This innovative approach provides users with a more efficient means of developing prefabs and enhances their creative capabilities.

Many drugs are traditionally prescribed at standard dosage despite a high variability of their absorption and disposition between patients. For critical drugs (anticancer, anti-HIV, antifungals, anti-epileptics, psychotropic agents etc.), too low concentrations may lead to inefficacy and sometimes selection of drug-resistant cells or viruses. Conversely, too high concentrations increase the risks of adverse effects and toxicity. Such drugs are said to have a “narrow therapeutic margin”. Monitoring of circulating drug concentrations in the patients, also called “therapeutic drug monitoring” (TDM), represents the best way to optimize drug dosage and prevent toxicity or lack of effectiveness, when no accurate efficacy markers are measurable. Still TDM has slowly developed until recently, because both the drug measurement and the interpretation of concentration results were demanding. During the last decade, laboratory technologies have markedly progressed and no longer represent a limiting factor. At present, dozens of drugs can be easily analyzed. A prerequisite for the wide accessibility of TDM to all patients that require it is that physicians, pharmacists, nurses and even patients can easily interpret drug concentration results and adjust therapies accordingly.

MiMecore Therapeutics is an emerging glycobiologics company developing a novel suite of biomimetic proteoglycan molecules with the potential to provide a ground-breaking therapeutic approach to the restoration and repair of soft and connective tissues of the body damaged through aging and disease. The Company’s glycotherapeutic strategy presents a biologically innovative platform for restoring and maintaining the structure and function of the dermal extracellular matrix.

TMST (targeted modulated sound therapy) uses specific sound frequencies in the audible range to tune brain activity that has gone off synch. Their first target is spasticity, involuntary muscle contractions produced by imbalanced brain activity– and associated with cerebral palsy, stroke, MS, partial spinal cord injury, traumatic brain injury. Proprietary TMST devices will have a life changing impact on millions of adults and children suffering from spasticity and other CNS-related disorders.

Monkey in the Middle Apps is a company which makes work fun for students to practice their middle school subjects. Play. Learn. Repeat. Monkey In The Middle Apps LLC has designed apps like Middle School Math 7th Grade and Middle School Math Pro 7th Grade.

Mootus is a platform for online legal argument for law students and new lawyers. Mootus is reinventing the way lawyers work through the platform for open, online legal argument, which lets users collaborate, and compete to solve legal issues submitted by other users, with the results of that activity posted to an open legal repository. Mootus was founded on 2012 and is headquartered in Boston, Massachusetts.

MegaMIMO's patent-pending technology alleviates the wireless capacity crunch. They've demonstrated that it delivers ten times more data per unit of spectrum as compared to today's technologies, and requires no changes to end-user devices.

Mogotest is a front-end testing and verification tool designed to help companies ensure that their web sites render properly across various web browsers and platforms. Mogotest can spider your web site or test individual pages to help you spot browser inconsistencies and areas in need of optimization. We take the pain out of web testing so you can focus on building the features that make your product truly unique.