MassChallenge

Newton Tech specializes in mobile physiotherapy technology aimed at assisting stroke patients in their recovery. The company's flagship product, Mobi, provides individualized insights and real-time fall detection and prevention. By tracking patients' movements and recording their walking patterns, Mobi helps users develop a unique movement signature, which in turn offers personalized movement insights. Newton Tech's mission is to facilitate a healthier future for stroke survivors through innovative technology that enhances rehabilitation and promotes safety.

Galileo Innovations develops human performance-optimizing biotech gear and equipment for athletes, first responders, military members, and labor industry workers. Its proposed technology, KordoFan, augments users with actionable insights concerning environmental and biometric hazards in real-time to target heat injuries; through an array of biomimicry cooling designs, the device aids in speed, agility, mental clarity, muscle recovery, strength, and stamina during training/shifts.

MIPRONS is on a mission to develop a space propulsion system for nanosatellites.

Ronawk is a biotechnology company based in Olathe, Kansas, founded in 2019. The company specializes in developing T-Block technology, which facilitates the mass production of patient-specific biologics for treating various conditions, including diseases, cancer, organ injuries, and burns. Ronawk's proprietary technology allows for the growth of primary stem cells in a three-dimensional environment, preserving the essential characteristics of the cell population outside the body. This innovative approach enables the rapid expansion of stem cells, which can be utilized for early-stage diagnostics and tissue repair in reconstructive surgeries. By focusing on efficient and high-density cell growth, Ronawk aims to advance tissue generation and disease modeling for improved patient outcomes.

Netnoids Rx Laboratories operates a cancer contract research organization that uses patient-derived organoid model systems to help find a cure for rare cancers.

NemoCare is developing the smartest and most comprehensive patient monitoring and management system. It is an innovative, continuous vital sign data acquisition, analysis and prediction engine that combines unobtrusive wireless wearable sensors and networks, analytical algorithms and big data to provide affordable continuous, high resolution monitoring for all newborns in hospital, and at home. We use design thinking principles to build life-saving technologies that will transform the way healthcare is delivered. Our current area of work is in newborn and maternal care.

Developer of water desalination technology designed to turn polluted water into fresh water. The company's technology utilizes a patented process to address water scarcity and pollution, enabling municipalities and industrial facilities to access clean water resources.

Natrion LLC specializes in the design and manufacture of sodium-ion batteries, focusing on large-scale energy storage solutions for renewable energy applications. Founded in 2017, the company is headquartered in Greenwich, Connecticut, and aims to enhance the efficiency of renewable energy generation by providing energy storage systems that leverage solar and wind power. Natrion's ceramic solid-electrolyte batteries are engineered to support power deployment for various sectors, making solar energy more accessible and cost-effective for residential, agricultural, and military uses.

Uniphage is a biotech company that eliminates bacterial infections by combining the power of bacteriophages with artificial intelligence. Their first target disease is citrus greening, an incurable and debilitating disease that costs the United States more than $2 billion each year. Uniphage created the first commercially effective models for computationally predicting safe bacterial viruses against target bacterial infections, as well as discovered a variety of targets. This enables them to deliver new antimicrobial, safe, and precise products to market much more quickly.

Developer of material technologies intended to provide virus and bacteria protection for up to several months. The company's core nanotechnology is as safe as water for human contact yet works against some of the most concerning germs, such as MRSA, and norovirus, enabling users to reduce the infections from surfaces while also reducing chemical release and plastic waste to the planet.

NurLabs develops label-free and reagent-free diagnostics to detect cancer early when it is most treatable.

Intelligent NanoFiber, Inc. is a company based in College Station, Texas, that specializes in the design and manufacture of NanoFiber, an advanced absorbent material made of polypropylene. Established in 2020, the company focuses on the development of this innovative nano-material, which is capable of capturing and neutralizing toxins and infectious diseases. The applications of NanoFiber span various sectors, including public safety and defense, where it is utilized for air filtration, waste cleanup, heat insulation, and environmental initiatives such as desert greening. Through its advanced technology, Intelligent NanoFiber aims to address critical challenges in safety and environmental sustainability.

Developer of an interferometry technology platform designed to generate images. The company's platform specializes in microfabrication, X-ray, and neutron grating interferometry which can generate information through the interaction of electromagnetic waves, enabling industries to improve the performance of gratings with support structures.

Transcera is a biotechnology company focused on advancing the treatment of chronic diseases through innovative drug delivery systems. It has developed a novel lipid-based platform that enhances the targeting and absorption of therapeutic molecules, allowing larger drugs to effectively cross cellular barriers. This approach aims to improve the pharmacokinetics of treatments, ultimately benefiting patient outcomes by ensuring that medications are delivered more precisely and efficiently. Transcera's technology represents a significant advancement in drug delivery, addressing critical challenges in the management of chronic conditions.

Asan Therapeutics utilizes a novel technology that simplifies the treatment of cancer patients to receive only a single injection instead of several painful injections.

Neurava is working to develop a first of its kind, wearable diagnostic for epilepsy patients, including those at risk of SUDEP.

NERAMCO develops smart polyethylene fibers and fabrics, SVETEX, for the textile industry. SVETEX materials have superior functionality and can be used as a sustainable/recyclable material that reduces water consumption and pollutants. The company develops apparel for children with skin disorders, and temperature-reducing underwear for menopausal women (for comfort) and all men (for improved fertility).

NeuroGeneces is a seed-stage startup dedicated to enhancing memory and mitigating cognitive decline associated with aging. The company leverages advanced research in sleep and neuroscience to improve the natural memory consolidation processes that occur during sleep. It has developed an EEG-based headband equipped with algorithms that synchronize acoustic stimuli to users' Slow Oscillations (SOs) during slow wave sleep, thereby enhancing memory recall. Additionally, NeuroGeneces offers a device that can detect neurodegeneration long before cognitive symptoms appear, allowing for timely interventions. This device monitors various sleep parameters, including quantity and quality, while assessing changes in heart rate variability. By providing valuable clinical decision support for healthcare professionals, NeuroGeneces aims to empower users to optimize their mental and physical performance.

FLITE has a laser-based technology that changes the surface topology of familiar materials (glass, plastic, metal, ceramics and semiconductors) to make them attract or repel water and oil - without the use of chemical coatings.

Gensor develops a virus testing platform based on the gene field-effect transistor technology.

AcousticaBio is a biotechnology company focused on reformulating intravenous medications for subcutaneous delivery. The company has developed a fluid processing technology that creates complex microparticles, enabling the conversion of biologic products typically administered intravenously into highly concentrated, small-volume injections suitable for under-the-skin administration. This innovative approach allows patients to self-administer essential medications with less pain and discomfort, reducing the need for lengthy hospital visits and enhancing overall patient convenience.

Diamante is a company that develops and manufactures autoimmune disease diagnosis devices using nanomaterials. It exploits plants as bioreactors for the sustainable production of nanoparticles based on modified plant viruses that are used in developing new tools. Diamante was founded in 2016 and is headquartered in Verona, Italy.

Sparrow Quantum A/S is a privately held company that develops and commercializes photonic quantum technology components based on research and patents developed in the Niels Bohr Institute Quantum Photonics Lab. The Niels Bohr Institute’s Quantum Photonics Lab, headed by professor Peter Lodahl, is part of the Danish Center for Quantum Innovation, Qubiz, funded by Innovation Fund Denmark –– a national large scale investment in quantum technologies.

UNISERS is based on nanotechnology and Raman spectroscopy and abbreviates “Universal Surface-Enhanced-Raman-Spectroscopy”. Their patented technology is the only known surface-enhanced Raman spectroscopy method which can detect all non-volatile impurities regardless of their chemical properties. Therefore, they can analyse multiple different impurities in liquids within the same test. Their technology is based on sample preparation and Raman scanning. The sample preparation is non-chemical and amplifies the Raman signal of impurities by a factor of ~1,000,000 and makes trace impurities detectable.

Gelatex Technologies is a Techstars-backed materials technology company that invented the fastest technology for producing bio-based nanofibers on a large scale. It is a platform technology that enables faster and up to 100 cheaper nanofiber production for applications like 3D scaffolds for tissue engineering, cultured meat, bio-based filters, eco-friendly leather-like textile, energy storage, wound care, and many more. The technology is patent-pending and the machinery fully functional. The company was founded in 2016 and until COVID-19 pandemic developed eco-friendly leather-like textile from gelatin nanofibers, using this nanofiber production technology as part of the process. COVID-19 was a trigger to understand the wider potential of the technology which then led to pivot. The company is based in Estonia and holding incorporated in UK (2019).

Developer of fluidic devices intended to improve the effectiveness of laboratory tests, experiment with innovative therapeutic approaches and reduce animal testing. The company's device includes a wide set of applications, such as cosmetics, oncology and pharmaceutical, toxicology and pollution, nutraceutical and agri-food, enabling clients to cultivate three-dimensional tissues, similar to human ones, in clinically relevant dimensions on which to operate in vitro tests and take decision accordingly.

Fabriloo's VRB technology uses an innovative unique composite hydrophilic and hydrophobic membrane to reduce the volume of human waste in toilet sites by a factor of 10. It eliminates environmental contamination and the need for infrastructure. Fit for ALL environments, it is compact, light, and easily stored for disaster preparedness. The scalable design enables immediate latrine facilities for early-stage response and beyond, saving stakeholders resources, precious time, and logistical burdens.

Pacify Medical Technologies is a medical device startup with patent-protected technology that sprays skin tissue on wounds for fast recovery.

Developer of an aqueous technology platform designed to deliver ultra-low friction and efficient lubrication relevant to various medical and technological applications. The company specializes in using hydration water as the lubricating element which spontaneously adsorbs and coats biological as well as artificial surfaces, enabling healthcare and pharmaceutical professionals to coat biological surfaces and also provide the vehicle to encapsulate active pharmaceutical ingredients or supplements and to deliver these to targets that currently are difficult to reach.

TioTech specializes in the development of advanced titania (TiO2) materials for lithium-ion batteries, aiming to enhance their performance and safety. The company's flagship product, TitanBTM, is engineered to function as an anode material, enabling batteries to charge in under six minutes while significantly extending their lifespan. TioTech's proprietary processing methods for titania nanoparticles ensure that the batteries not only charge quickly but also maintain safety across a range of temperatures, including extreme cold. This innovative approach addresses common challenges in battery technology, positioning TioTech as a leader in the next generation of energy storage solutions.

Kinoko Tech Ltd., founded in 2019 and based in Jerusalem, Israel, specializes in the production of alternative protein products derived from fungi. The company focuses on utilizing deep-tech fermentation processes to create nutritious and flavorful superfoods. By fermenting fungal mycelium, Kinoko Tech develops products that are rich in protein, essential amino acids, and offer a scrumptious taste and aroma. Their offerings are designed to cater to health-conscious consumers seeking allergen-free, gluten-free, and cholesterol-free dietary options. Through its innovative approach, Kinoko Tech aims to promote sustainable food solutions while elevating the nutritional value of everyday meals.

SGMA specializes in coatings & advanced materials using Sol-gel process. It develops practical, sustainable solutions for today’s global problems. SGMA’s technology platform has a wide range of applications. The first area we are aiming to address is that of food packaging. The company is actively engaged in a program to help Starbucks, McDonald’s, Coca-Cola, Yum! Brands and the World Wide Fund for Nature. SGMA’s Technology Platform provides a quickly scalable solution to address the zero-plastic goal with a potential cost reduction, as the solution is delivered via a mono-material which is 100% recyclable. It has applications beyond the initial coffee cup solution, being able to address trays, boxes, and beyond. The company is led by CEO Dr Fanya Ismail and was founded in 2017.

Limula Biotech is a Swiss company specializing in the design and development of an automated system for manufacturing cell and gene therapies. The company has created a patented platform that enables the distributed production of genetically engineered cells directly at the patient's bedside, utilizing a patient's white blood cell sample. This fully closed bioreactor system minimizes human intervention during the manufacturing process while maintaining control over cell culture parameters. By facilitating on-site production in hospitals, Limula's technology aims to enhance the safety, accessibility, and efficiency of personalized gene therapies, ultimately reducing time, costs, and logistical challenges. Founded in 2018 and based in Lausanne, Switzerland, Limula Biotech is committed to revolutionizing the delivery of ex vivo gene-engineered cell therapies.

Naturbeads, a company working to manufacture a replacement ato the ocean-polluting microbeads that, despite initial bans in “rinse-off” cosmetics, are found in many personal and home care products and paints. Naturbeads manufacture a biodegradable alternative to plastic microbeads that could reduce micro plastic pollution in the oceans. The technology to create the cellulose microbeads was developed at the University of Bath by Professors Janet Scott and Davide Mattia from the Centre for Sustainable Chemical Technologies in 2017

Graphene Composites Ltd (GCL) is a nano-technology startup. In partnership with the UK government-funded Graphene Application Centre at the Centre for Process Innovation (CPI), we are combining graphene (the strongest material known) with aerogel (the lightest material, and one of the best insulators/shock absorbers) into a composite that should be roughly 100x stronger than steel, and less than 1/100th of its weight.

Developer of nanotechnology intended to solve challenges across medicine and other industries. The company uses different types of biomaterials as building blocks and has fabricated diverse types of systems such as nanoengineered hydrogels, nanosized molecular delivery systems, and nanocomposite materials, helping businesses across different industries to use nanotechnology and grow their business.

Solenic Medical, Inc. is a medical device company founded in 2019 and based in College Station, Texas. It specializes in developing a non-invasive treatment for infected metallic implants using a technology that employs alternating magnetic fields generated by external coils. This innovative approach targets biofilm on the surfaces of medical implants, which is a significant complication in surgeries like knee and hip replacements, as well as in trauma-related procedures involving plates and rods. The technology has the potential to replace the costly and risky two-step revision surgical procedure currently used to address chronic infections in medical implants, thereby offering a safer and more effective solution for patients.

Developer of nanotechnology designed for the agriculture industry. The company's technology improves food safety through the development of novel methods for cleaning and sanitizing, enabling clients with the feasibility of employing nanotechnology to replace traditional post-harvest chlorine wash.

Developer of a peptide and protein purification technology designed to revolutionize recombinant production processes. The company's technology facilitates the production of enhanced purity products, significantly diminishing the purification challenges prevalent in modern chemical (peptide synthesis) and biological synthesis (recombinant) methods to meet specific requirements, enabling clients to efficiently overcome purification and economy-to-scale obstacles encountered in stock breeding.

Amphasys is a technology company specializing in chip-based single-cell analysis technology that aims to simplify and expedite complex cell analyses, making them accessible at the point of use rather than solely in advanced laboratories. Founded in 2012 as a spin-off from Axetris AG, Amphasys developed its core technology in 2004 in collaboration with the Swiss Federal Institute of Technology Lausanne. Through extensive research across various cell types, it has demonstrated versatility for applications such as pollen and milk analysis. The technology streamlines processes by eliminating the need for time-consuming sample preparations, such as cell labeling, and reduces reliance on costly laboratory infrastructure. This enables clients to perform label-free analyses of single-cell characteristics, including cell size, morphology, viability, and differentiation. Amphasys has received recognition for its innovation, including the prestigious Swiss startup prize from the W.A. de Vigier Foundation in 2013.

Developer of drug delivery solutions intended to facilitate enhanced absorption of co-administered therapies. The company offers novel drug delivery solutions built around its proprietary permeation enhancer, being able to replace current intravitreal injections of biologics with eye drops, enabling users to get patient safety, patient compliance, and decreased health care costs.

Naoris Ltd is a cybersecurity firm that harnesses blockchain technology to develop a decentralized security ecosystem. It offers a range of innovative products designed to enhance digital security for various organizations, including Naoris Distributed Security Ecosystem (DSE), which safeguards sensitive information across different business environments. Its Naoris Distributed Core (DC) technology focuses on application and cloud security, allowing users to manage access and monitor governance. The Naoris Legion solution aims to prevent undetectable cyberattacks, while Naoris DOT protects critical infrastructure such as SCADA systems and IoT devices. Additionally, Naoris Distributed Data Loss Prevention (DDLP) provides organizations with tools to secure intellectual property and sensitive data against unauthorized access. Founded in 2017 and headquartered in London, Naoris is positioned as a leader in next-generation cybersecurity, catering to a wide array of clients from startups to government entities, utilizing advanced technologies like distributed ledger technology, artificial intelligence, and machine learning to enhance security measures.

Microbial Pulse Diagnostics is developing and deploying an innovative NIST technology for the rapid measurement of antimicrobial susceptibility. This technology “takes the pulse” of bacterial cells, sensing changes in their metabolism, motility, and growth after exposure to an effective antibiotic.

ChondroNest is focused on developing medical technologies aimed at cartilage reconstruction, specifically targeting conditions such as Osteochondritis and Osteoarthrosis. The company is creating a device made from modified biopolymers intended for in vivo use, facilitating easier and more effective reconstruction surgeries for surgeons. ChondroNest plans to conduct preclinical tests on animal models before moving on to human trials. Following these initial trials, the company intends to license its product to major MedTech companies for sales and marketing purposes, while maintaining control over the production of its ChondroNest™ pastes.

NALA Systems provides environmental services. New reverse osmosis membranes are what the industry has been waiting for. Reverse osmosis has been proven to be the most efficient way to purify water.

Tzofen is a biotechnology company focused on developing a novel biological platform aimed at treating various types of cancer. This innovative platform has demonstrated the ability to eliminate cancer growth both in vitro and in vivo, highlighting its potential to significantly impact cancer treatment. By advancing this technology, Tzofen seeks to contribute to saving millions of lives affected by cancer.

Parx Plastics recognized a growing demand for plastics with antibacterial/antimicrobial properties and from their expertise they knew that the available solutions to achieve such materials were not suitable for large-scale application/adoption because of their possible harmful effects on humans, animals or the environment as a whole. They had foreseen the dangers, insecurities and disadvantages of these solutions. Over four years of dedicated biomimetic research has been invested to create a 100% safe and biocompatible technology to inhibit the growth of bacteria on the surface of plastic with the use of a Biomimetic approach in the design and engineering of the materials. The discoveries and inventions done during this research are truly unique and groundbreaking. A team of 11 professors, scientists and researchers with decades of experience in the field of Nano- and biotechnologies and skilled in chemical analyses and chemical-physical and microbial analyses have been working together with a renown European university for chemistry. The result is a worldwide patent-pending innovation for highly effective plastics with an antibacterial/antimicrobial effectiveness rate of 98-99% measured according to ISO 22196 and most of all: safe. Parx Plastics Sanipolymers are safe for humans, safe for animals and safe for the environment.

NemoCare is developing the smartest and most comprehensive patient monitoring and management system. It is an innovative, continuous vital sign data acquisition, analysis and prediction engine that combines unobtrusive wireless wearable sensors and networks, analytical algorithms and big data to provide affordable continuous, high resolution monitoring for all newborns in hospital, and at home. We use design thinking principles to build life-saving technologies that will transform the way healthcare is delivered. Our current area of work is in newborn and maternal care.

BINK Bio is working on developing biotech alternatives to reduce environmental damage. The company focuses on and technologies in the fields of biotech based dyes.

Sano Chemicals is an early stage biotechnology company primarily focused on the development of novel anti-infectives for clinical and agricultural use. The word “Sano” is derived from the Latin word meaning health, thus, they are focused on the development of products that will promote their health and a healthy and sustainable environment. Sano Chemicals is focusing on the development of antifungal treatment options for fungal infections and antifungal bio-control methods for crops. Their goal is to innovate the anti-fungal industry. The antifungal occidiofungin is a completely unique antifungal compound discovered by researchers at Mississippi State University and Texas A&M University. Novel applications in occidiofungin's use are being developed through the innovative endeavors of their scientists. Products that cure fungal infections (nail, skin, and systemic), as well as products that promote a sustainable food supply by targeting fungal diseases in plants are being developed.

Manufacturer of photocatalysis-based technologies intended to remove per and poly fluoro alkyl substances. The company's platform breaks down toxic PFAS and eliminates them from the ecosystem by removing toxic chemicals from water, enabling water utilities and manufacturers to cost-effectively remediate PFAS and meet regulatory requirements.

OrganoTherapeutics is a company focused on developing medical drugs aimed at treating Parkinson's disease. It utilizes advanced human-specific mini-brain models that accurately replicate the pathology of Parkinson's disease for the discovery and development of effective drug candidates. By employing three-dimensional models derived from both healthy individuals and patients with Parkinson's disease, OrganoTherapeutics identifies the therapeutic potential of various compounds and analyzes data using artificial intelligence. This innovative approach facilitates the screening of new molecules, allowing researchers to advance novel drug candidates. The company has already developed proprietary drug candidates and has access to extensive libraries for further research and development.

Developer of respiratory devices designed to administer medication in the form of inhalation into the lungs. The company specializes in designing and manufacturing nebulizers that are used for the treatment of asthma, cystic fibrosis, and other respiratory diseases or disorders as well as the product avoids medication errors and does not require cleaning or disinfection, enabling the medical community and patients to optimize treatment outcomes and overall quality of life that use nebulizers.

Neurosoft Bioelectronics specializes in the development of soft implantable electrodes designed to interface with the nervous system for diagnosing and treating neurological disorders. Based in Geneva, Switzerland, the company has created next-generation electrodes that are compliant and conformable, addressing the limitations of existing stiff devices. Their flagship product, SOFT ECoG, is a subdural electrode that records from and stimulates the brain's surface, enhancing recording quality and minimizing MRI artifacts. Neurosoft's technology promotes long-term bio-integration, adapting to both static and dynamic mechanics of neural tissue, which can improve therapeutic outcomes for patients and expand the applications of neural interfaces in clinical settings.

TechnoCarbon, based in France, is a startup focused on transforming the architecture and construction industries through its innovative composite material, CarbonFibreStone™ (CFS™). This high-performance material aims to replace traditional resources such as concrete, steel, and aluminum, which are known for their significant environmental impact and high emissions. By employing patented low-carbon technology, TechnoCarbon develops a new family of materials suitable for a wide range of applications, including construction, infrastructure, aerospace, defense, luxury goods, furniture, and high-fidelity audio products. The company's approach not only enhances technical performance but also promotes energy and natural resource savings, contributing to a more sustainable future.

Manufacturer of nanocoating materials intended to create a strong protective penetrative coating that covalently bonds to the substrate. The company's materials are manufactured through hydrophobic nano-coating which repels stains and water, thereby enabling clients to improve of the nature and quality of the surfaces and structures with specialized cleaners, sealers, and stains.

Levitection Ltd is a scientific research and development company based in Haifa, Israel, specializing in advanced electromagnetic imaging technology. Founded in 2015, the company has developed the world's first Near Field Threat Detection (NFTD) systems, which utilize artificial intelligence to detect concealed weapons in open, highly-trafficked public areas. Levitection aims to transform traditional scanning methods by providing standoff detection capabilities in environments such as transportation hubs, stadiums, casinos, hotels, mass public events, and educational campuses. The company's technology prioritizes individual privacy and convenience while enhancing public safety.

Levitection Ltd is a scientific research and development company based in Haifa, Israel, specializing in advanced electromagnetic imaging technology. Founded in 2015, the company has developed the world's first Near Field Threat Detection (NFTD) systems, which utilize artificial intelligence to detect concealed weapons in open, highly-trafficked public areas. Levitection aims to transform traditional scanning methods by providing standoff detection capabilities in environments such as transportation hubs, stadiums, casinos, hotels, mass public events, and educational campuses. The company's technology prioritizes individual privacy and convenience while enhancing public safety.

Developer of nanotechnology intended to solve challenges across medicine and other industries. The company uses different types of biomaterials as building blocks and has fabricated diverse types of systems such as nanoengineered hydrogels, nanosized molecular delivery systems, and nanocomposite materials, helping businesses across different industries to use nanotechnology and grow their business.

Developer of molecular technology intended to discover and deliver beneficial bacteria. The company's technology facilitates the production of next-generation probiotics, enabling clients to improve the wellness of humans and animals.

Aniluxx Biotechnology is a development stage biopharmaceutical company with a mission to improve companion animal health and well-being. The Company’s strategy is to translate its deep pipeline of topically formulated therapeutics, predicated on compounds that have already been identified as safe and effective in humans, into therapies for dogs, cats, and horses, that are easy to apply, virtually unnoticeable, and absent the harsh side effects of systemic medicines.

Developer of an antibody drug discovery platform designed to reprogram cancer cells to treat advanced cancers to be centered around proprietary artificial intelligence. The company's platform designs custom antibodies with high selectivity and specificity linked to proprietary cellular reprogramming lab assays, its drugs modulate activities of a novel set of growth factors called dual smad inhibiting protein dips, thought to drive the growth and spread of cancer, enabling physicians to get access to novel drugs in areas of unmet medical needs.

Mantle Biotech engineers binding proteins that can accurately identify disease biomarkers in patient samples, using directed evolution to modify heat-stable proteins produced by microbes. It allows the company to develop new diagnostic capabilities, producing high-quality binding proteins that are more stable and affordable than traditional reagents. This reagents can be adapted to a range of diseases and test formats, allowing the team to identify pain points throughout the broader diagnostic industry. Mantle Biotech was founded on 2019 and is headquartered in Cambridge, Massachusetts.

Nanoglue is a Swiss company based in St. Gallenkappel that specializes in the manufacture of a unique nanotechnology paste designed for wound healing. This innovative product enhances the body's natural self-healing processes and is particularly beneficial for patients undergoing skin transplants. Additionally, it aids in preventing bacterial infections associated with severe burns, sports injuries, and diabetic wounds. By utilizing advanced nanoparticle technology, Nanoglue aims to support surgeons in minimizing complications related to skin transplantation and promoting rapid recovery for patients.

Clara Biotech is focused on developing a platform technology for the isolation and purification of exosomes from small fluid samples, facilitating liquid biopsies for early detection of various diseases, including cancer and Alzheimer's Disease. Unlike traditional methods that require lengthy ultra-centrifugation, Clara's platform can extract pure and viable exosomes from any biofluid source efficiently. This innovative process enhances the potential for precision medicine by enabling targeted drug delivery directly to specific cells. Additionally, Clara Biotech's technology supports the development of unique liquid biopsy assays, improving the accuracy of disease detection and addressing challenges faced by biopharma companies in the medical field. Overall, Clara Biotech aims to advance research into clinical applications, bridging the gap between laboratory findings and patient care through its exosome-based solutions.

Developer of implantable neuromodulation systems designed to effectively and safely treat patients with pelvic health conditions. The company's technology modulates distal target nerves locally by stimulating only the target and can be used to modulate innervation to muscles or organs alike, enabling patients to avail less invasive, safer, and more effective therapy for conditions like incontinence, sexual dysfunction, and chronic pain.

NuEyes Technologies Inc. specializes in developing advanced glasses and software designed to assist individuals with visual impairments, including conditions such as macular degeneration, glaucoma, and retinitis pigmentosa. The company offers electronic glasses equipped with an adjustable HD magnification camera that captures images and projects them onto the lenses, allowing users to see enhanced visuals tailored to their preferences for magnification and brightness. This technology is complemented by wireless, battery-powered, and hands-free voice-activated features for user-friendly operation. NuEyes provides two product variants: NuEyes Easy and NuEyes Pro. Founded in 2016, the company is headquartered in Newport Beach, California.

Silencions specializes in advanced acoustic technology aimed at reducing noise pollution through innovative material structures. The company's engineered, sub-wavelength periodic architecture significantly minimizes noise and vibration across various demanding sectors, including aerospace, automotive, construction equipment, and household items. This technology enables clients to effectively address noise issues in diverse environments, regardless of the source of the sound. Silencions is composed of an interdisciplinary team of scientists and engineers with extensive international experience from leading research institutes in Europe, positioning the company as a pioneer in vibration and noise suppression solutions.

Producing an effective chemotherapy solution with a fully automated tumor-on-a-chip, pre-prescription analysis.

AeroShield manufactures a super-insulating, nanoporous form of glass for energy efficient windows. The AeroShield material can be placed between two panes of glass, similar to a traditional double-pane, to create a product that is 50% more insulating than traditional windows, but with a payback period up to 5 times faster than windows of similar performance.

Pocket Innovations is a developer of a medical device designed to address the issue of pocket hematoma, a common complication arising from pacemaker, defibrillator, and deep brain stimulation implant procedures. The company's innovative device serves as the first preventative solution to this problem, aiming to reduce the incidence of pocket hematomas that can complicate post-operative recovery. By offering a method to prevent these costly and often problematic hematomas, Pocket Innovations provides medical practitioners with a valuable tool to enhance patient outcomes following implant surgeries.

Developer of a diagnostic platform intended to detect cancer at an early stage. The company's platform employs high-sensitivity technologies to detect subtle molecular changes and biomarkers associated with cancer cells, enabling clinicians and healthcare providers to make informed decisions regarding patient care, including personalized treatment plans and monitoring strategies.

Developer of a regenerative therapeutics platform designed to facilitate the commercialization of innovative discoveries in biotechnology. The company's platform focuses on the development of therapeutics based on modified mRNAs, that can reprogram heart cells to become stem cells, enabling scientists to develop technology to control networks of genes to regenerate cardiac tissue.

Developer of an anti-bleeding compound designed to stop blood loss instantly from injuries. The company's product is a powder with a fibrin-like structure that clots blood within seconds, enabling users to survive fatal bleeding injuries.

Developer of greenhouse canopies designed to increase crop production. The company's products embed advanced nano-materials into greenhouse glazing to convert wasted sunlight into usable light for increased plant photosynthesis, enabling farmers to decrease harvest time, increase crop yields and improve the overall quality of their produce.

Envic-Sense has created a measuring instrument that allows for the on-site detection of trace levels of heavy metals in water and soil. Utilizing Quartz Crystal Microbalance (QCM) technology, this instrument measures frequency changes in a quartz crystal coated with specific substances, enabling real-time analysis of contaminants without the need for heating. This established technology has been adapted for environmental applications, providing interchangeable measuring cells tailored for various heavy metals such as mercury, arsenic, cadmium, lead, and explosive materials like TNT. Each measuring cell is designed for multiple uses, typically up to ten tests, after which it can be recycled. As a result, Envic-Sense's solutions facilitate precise environmental monitoring and support informed decision-making regarding contamination management.

VisusNano Ltd. is a pre-clinical company based in London, United Kingdom, focused on developing a drug-eluting intraocular lens implant for cataract surgery. Founded in 2016, the company aims to enhance patient outcomes by reducing the risks associated with cataract procedures, such as intraocular inflammation, infection, and opacification. This innovative lens technology eliminates the need for postoperative eye drops and laser treatments, positioning it as a potential game-changer in both human and veterinary cataract surgery markets. Through its advancements, VisusNano seeks to revolutionize the standard of care in ophthalmic procedures.

ZeoVation produces and supplies zeolite materials to the sun/skin care, home care, healthcare, coatings, water and gas purification markets. Our ready-to-use zeolite products include nanozeolites and hierarchical zeolites. We are dedicated to providing assistance to the research and corporate R&D community to develop products relevant to their interests using the unique features of our featured zeolites.

Fluent BioSciences is a privately funded life science company focused on developing high-sensitivity molecular analytical products. Utilizing proprietary instrument-free micro-self-assembly technology, the company enables the analysis of extremely low molecular and cellular sample inputs. Its platform facilitates the instantaneous self-assembly of individual cells or molecules into millions of uniform partitions, allowing for sensitive and unbiased preparation of proteins and nucleic acids for sequencing applications. This innovative approach provides researchers in the biotechnology sector with enhanced capabilities for single-cell analysis, broadening their access to advanced analytical techniques.

EMet Nanotech specializes in advanced nanofabricated chip technology that enhances the cryo-electron microscopy (cryo-EM) sample preparation process, making it significantly faster and more efficient. By utilizing their innovative PicoCell, a one-step freezable imaging grid, the company streamlines the sample preparation that traditionally requires multiple steps and expensive robots. This technology not only reduces costs and time but also improves reproducibility in drug discovery, enabling biopharmaceutical companies to better understand diseases and develop effective therapies. EMet Nanotech's solutions aim to accelerate the development of new treatments in the biopharma sector, ultimately contributing to advancements in healthcare.

Annaida Technologies SA, founded in 2019 and based in Lausanne, Switzerland, specializes in the development of EmbryoSpin, an innovative device designed for biochemical research. This device performs microscopic nuclear magnetic resonance (µNMR) with a sensitivity that surpasses existing technologies by tenfold, allowing for chemical analysis at the scale of a single human embryo. EmbryoSpin is engineered for robustness and user-friendliness, making it suitable for non-invasive embryo viability screening in in-vitro fertilization and various biochemical studies. The company's advancements aim to enhance medical research capabilities, particularly in the context of reproductive health.

Clean Crop Technologies, Inc. specializes in innovative food processing technology aimed at reducing molds, toxins, and pests in grains and nuts. By utilizing a method that combines air and electricity to create ionized gases, the company effectively removes harmful substances without compromising food quality. This technology not only eliminates molds and pests but also extends the shelf life of perishable foods. Founded in 2020 and headquartered in Haydenville, Massachusetts, Clean Crop Technologies is focused on translating advanced research into commercial-scale solutions for the global grain and nut industries.

Microcaps AG specializes in developing innovative microencapsulation technology that facilitates the precise fabrication of monodisperse capsules and microparticles. Founded in 2018 and based in Zurich, Switzerland, the company focuses on scalable production through microfluidics, which allows for enhanced size control, precise dosing, and increased stability of microcapsules. Its technology is particularly beneficial for protecting pharmaceutical agents in drug delivery and encapsulating probiotics. Microcaps provides tailored solutions that significantly improve throughput rates and maintain quality, surpassing conventional production methods. The company's aim is to establish a fully-automated encapsulation micro-factory that streamlines the manufacturing process and meets the diverse needs of its clients in pharmaceuticals and cosmetics.

Haima Therapeutics is a pre-clinical stage biotechnology company. It focused on developing bio-inspired therapies for the treatment of bleeding and other blood-related ailments. They developed a novel, nanoparticle-based synthetic hemostatic technology, called SynthoPlate, that can staunch hemorrhagic bleeding by binding to the site of injury and amplifying your body’s natural clotting mechanisms. It was founded in 2016 and is headquartered in Cleveland, Ohio.

SiNON is dedicated to improving the lives of those who suffer from debilitating neurological diseases by increasing the ability of drugs to cross the Blood Brain Barrier (BBB).

Nevomo, a company founded in 2017 and based in Warsaw, Poland, specializes in developing advanced High-Speed Railways (HSR) utilizing magnetic levitation, linear motor technology, and autonomous control systems. It is recognized as the only firm globally focused on gradually introducing Hyperloop-inspired solutions to enhance the railway sector. Nevomo's patented magrail technology enables the modernization of existing conventional railway lines, allowing speeds of up to 300 kph (186 mph) on standard lines and 415 kph (258 mph) on HSR. This system maintains the operational capabilities of traditional railways, enabling operators to utilize existing rolling stock. The magrail system can further evolve into a vacuum version, known as hyperrail, which could achieve speeds of 600 kph (373 mph) and eventually transition into hyperloop technology with speeds reaching 1200 kph (746 mph). The estimated capital expenditure for retrofitting lines to the magrail standard is comparable to building new highways, while offering significantly lower energy and maintenance costs than current HSR systems. The company has established partnerships with firms such as TME Transfer Multisort Electronics and Microsoft, and has a strong R&D team led by notable experts in the field.

Strand Therapeutics Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2017. The company focuses on genetically programming mRNA to develop innovative therapies that enhance patient outcomes. Utilizing its mRNA programming technology, Strand Therapeutics creates gene therapies powered by synthetic biology, which include immunotherapies designed to stimulate cells to produce cancer-targeting proteins. This approach improves the immune system's ability to combat cancer by enabling precise control over the timing, location, and intensity of therapeutic protein expression. The technology leverages cell-type specific expression and responds to specific molecular signals, allowing for tailored therapeutic interventions.

Developer of a non-touch room disinfection and energy-efficient lighting technology designed to neutralize viruses, bacteria, and fungi on exposed surfaces within healthcare facilities. The company offers an on-demand, one-touch activation platform using wireless control and monitoring and LED lighting technology for facilities to reduce and eliminate as many pathogens as possible in a cost-effective and efficient way, reducing the chances of healthcare-acquired infections.

SpinDrive specializes in the development of advanced levitation technology, focusing on magnetic bearing systems that enhance energy efficiency while promoting oil-free solutions. Their innovative systems include magnetic bearing sensors that monitor shaft positioning and relay this information to a magnetic bearing controller. This technology allows clients to significantly improve system efficiency, reduce material consumption, and lower maintenance costs, making it a valuable solution for industries seeking sustainable and efficient operational practices.

Flextrapower is a remote monitoring company powered by graphene technology, a disruptive material with unique properties that allow for ground-breaking biomedical applications. Graphene is stronger than steel, yet incredibly lightweight and flexible. It is electrically and thermally conductive but also transparent. It’s one million times thinner than the diameter of a single human hair. Our team has developed and patented a method to seamlessly embed graphene sensors into flexible materials, like clothing. This method enables us to develop state-of-the-art remote monitoring products that advance health outcomes and improve patient care. Currently, Flextrapower has developed a smart insole that detects diabetic foot ulcers, an EMG-integrated smart shirt, and a COVID-19 mask featuring a layer of graphene.

Uneecops Technologies Ltd. is the leading provider of IT solution to businesses of variable sizes. With alliances with leading brands, such as ESRI, QlikView and SAP. Uneecops is #1 partner of SAP Business One in N.India and provide SAP Business One solution to small and medium sized business houses. Uneecops also developed various SAP B1 Add-Ons for Pharma, Campus Management, Human resource management, etc. Incepted in 1996, the company has more than 500 satisfied clientele in public and private sectors in India, South East Asia, Africa and the US. The Company has developed various products including HR-One (HRMS Solution), PayEdge (Payroll Management Solution), Ctrl-A (Campus Management Solution). We also offer services pertaining to web development, business intelligence and GIS.

Magnomer is a manufacturer based in Boston, Massachusetts, specializing in innovative magnetic inks aimed at enhancing the recyclability of plastic packaging. Founded in 2017, the company focuses on developing printable magnetizable inks that serve as a design tool for consumer brands and manufacturers. These inks improve the scalability of recycling processes for multi-layer plastics, which are traditionally challenging to recycle. By integrating their magnetic inks into packaging, Magnomer enables recycling facilities to utilize magnetic sorting technology, facilitating the efficient separation of materials. This approach aligns with the principles of the circular economy, promoting better sustainability in packaging without necessitating changes in manufacturing processes.

PionEar Technologies is a medical device company that develops technologies for ear and hearing disorders. Its products include a minimally invasive tympanostomy tube that prevents cellular and bacterial adhesion and improves drug delivery to the middle and inner ears, enabling clients to modernize treatment of chronic ear infections and hearing loss and provide proper treatment services.

MicroQuin is a biotechnology company founded by Dr. Scott Robinson and Yang Zheng, focused on developing innovative therapeutics to tackle significant diseases, particularly cancer. The company has created a targeted delivery platform for chemotherapy that selectively directs treatment to cancer cells while sparing healthy cells from toxicity. This approach involves binding to cancer cell surfaces, disrupting cellular structures, and promoting cell death, thereby enhancing the efficacy of existing chemotherapeutic agents for various cancers, including breast, lung, prostate, ovarian, and melanoma. MicroQuin has received recognition as a finalist in the 2018 MassChallenge and as a winner of the CASIS/Boeing Prize, which supported research conducted on the International Space Station. The company is headquartered at LabCentral in Cambridge, Massachusetts.

NovoThelium is a biotechnology company focused on developing innovative solutions for breast reconstruction, specifically through the creation of a tissue-engineered nipple matrix. Founded in 2015 by biomedical engineers motivated by personal experiences with breast cancer, the company aims to address the challenges of nipple regeneration following mastectomy. NovoThelium's approach involves a decellularization process that utilizes breast tissue from human donors, removing DNA and donor cells while preserving essential proteins and structures. This process allows breast cancer survivors to regenerate a nipple using their own cells, resulting in a more natural appearance, including proper projection, pigmentation, and enhanced sensation.

Folia Water, Inc. is a Pittsburgh-based company founded in 2016 that specializes in manufacturing innovative water filter papers. The company has developed a patented process utilizing large-scale paper machinery to produce low-cost, nano-metal functionalized materials. Folia Water's primary product is an affordable paper water filter designed to significantly reduce waterborne pathogens, making clean drinking water accessible to a broader audience. Targeting emerging markets, the filters are priced at approximately $0.20 for 20 liters, catering to the needs of around 3 billion consumers. Folia Water operates in the business-to-business sector, partnering with enterprise-scale consumer brands and conducting pilot projects with notable companies such as Unilever in Bangladesh and a multinational corporation in Mexico. Through its efforts, Folia Water aims to enhance the quality of life for working-class consumers by providing high-quality, affordable water purification solutions.

Scintia focuses on enhancing education and research in synthetic biology by providing innovative solutions designed to overcome barriers in biotechnology development. The company manufactures laboratory equipment and educational kits that facilitate hands-on learning experiences in genetic engineering. These kits include all necessary materials for conducting laboratory experiments, accompanied by comprehensive teaching guides for educators and students. By simplifying the educational process, Scintia enables users to engage in practical biological reactions, fostering a deeper understanding of synthetic biology concepts.

ALAnostics is a speciality Biopharmaceutical company, and a spin-off from the University of Geneva, developing tumour paint to help surgeons identify and remove breast cancer in real-time during breast cancer surgery.

Lab-on-Fiber GmbH engages in the development, commercialization, and production of fiber delivery and laser systems. It offers surgical fiber probes and urology fiber probes. Lab-on-Fiber GmbH is based in Halle, Germany.