MassChallenge

Phimentum enables general dentists without specialized training to offer braces to their patients. This opens a high-profit revenue stream for dentists and lowering cost and geographic barriers for patients.

LucyDX is on a mission to prevent blindness in diabetics through early detection. The company's technology helps diabetics who want to save their eyesight by detecting retinal eye disease early and is helping medical professionals track and treat eye damage before it becomes permanent.

US Sleep Apnea aims to combat the increasing Sleep Apnea pandemic by enlisting the help of dentists. Sleep apnea is a developing problem that will kill 48 million individuals prematurely. Dentists are perfectly positioned to solve this need; but, because this is the only medical service a dentist can provide, operational inefficiencies and expensive start-up costs have kept the majority of dentists from delivering care. The US Sleep Apnea platform provides dentists with a digital solution that automates every touchpoint in the patient experience and dramatically saves front office expenditures.

Digbi Health, LLC provides digital therapeutics services. It offers health programs, such as weight loss diets for skin and gut disorders, hypertension, elevated cholesterol, and diabetes. It also provides an online application to track 9-key metrics, such as stress, energy, and weight. The company is based in Mountain View, California with additional offices in Bengaluru, Karnataka and Taguig, Philippines.

Adaptilens, LLC is focused on developing an innovative injectable intraocular lens designed to provide patients with clear near and distance vision without the need for eyeglasses or contact lenses. This accommodating lens mimics the natural lens of the eye, allowing the ciliary muscles to change its shape for optimal focus at varying distances. By returning to its baseline elliptical shape, the lens facilitates clear vision for distant objects when needed. Founded in 2019 and based in Chestnut Hill, Massachusetts, Adaptilens aims to enhance the quality of vision for individuals, promoting a more natural visual experience.

Hubly Surgical Inc. is a medical device company focused on enhancing the safety of neurosurgical procedures. Founded in 2018 and headquartered in San Francisco, California, with an additional office in Chicago, the company has developed an integrated electric drill system designed to replace traditional hand-cranked drills. This innovative technology aims to reduce the high complication rates associated with common neurosurgical procedures, which can fail up to 20% of the time. The drill system features advancements such as drilling guidance, plunge prevention, and catheter guidance, making it suitable for both operating rooms and emergent settings. By streamlining bedside intracranial access and decreasing reliance on traditional operating room environments, Hubly Surgical seeks to improve the overall safety and efficiency of neurosurgery.

Dock Health is a Boston-based company that provides a HIPAA-compliant task management and collaboration platform specifically designed for the healthcare sector. Founded in 2016, Dock Health aims to address critical workflow challenges and inefficiencies faced by clinicians and their teams. By facilitating better communication and collaboration through a user-friendly and secure system, Dock Health strives to enhance patient care and ensure that essential tasks are completed effectively. The platform is suitable for healthcare teams of various sizes and specialties, empowering both clinical and administrative staff to work more efficiently within their organizations.

Dock Health is a Boston-based company that provides a HIPAA-compliant task management and collaboration platform specifically designed for the healthcare sector. Founded in 2016, Dock Health aims to address critical workflow challenges and inefficiencies faced by clinicians and their teams. By facilitating better communication and collaboration through a user-friendly and secure system, Dock Health strives to enhance patient care and ensure that essential tasks are completed effectively. The platform is suitable for healthcare teams of various sizes and specialties, empowering both clinical and administrative staff to work more efficiently within their organizations.

OrthoBistro is a healthcare company that has developed an innovative platform focused on orthopedic care. The platform is designed to enhance patient interactions with healthcare providers by offering a range of services including patient education, telemedicine, and physical therapy tools tailored to individual lifestyles. By facilitating meaningful communication between patients and their therapists, OrthoBistro aims to address common orthopedic questions and improve the overall patient experience in managing their health.

MDM Wound Ventures Inc. is a medical device manufacturing company based in Schertz, Texas, specializing in innovative products for wound care and surgical providers. Founded in 2014, the company is known for its EZ Debribe, a sharp debridement instrument designed to allow clinicians to precisely debride wound patients. The device features a uniform cutting plane and cutting flutes, providing a disposable option that enhances the debridement process. MDM Wound Ventures aims to improve patient outcomes while reducing costs associated with wound care.

DEBN Sp. z o.o., based in Gdansk, Poland, specializes in the development of a medical device known as the Drug-Eluting Biopsy Needle. This innovative prostate biopsy needle aims to reduce the incidence of infectious complications associated with transrectal ultrasound-guided biopsies (TRUS-Bx). The device features a polymer-coated biopsy needle and an anesthesia needle that deliver antibiotics directly to the prostate during the biopsy procedure. By allowing the co-administration of multiple antibiotics, the needle enhances the effectiveness of infection prevention strategies, particularly by utilizing antibiotics that are not suitable for oral prophylaxis. Established in 2017, DEBN focuses on improving patient outcomes in urology by addressing the risks of post-biopsy infections through targeted drug delivery.

Operator of a medical laboratory intended to provide various diagnostics tests to patients. The company offers tests based on the analysis of DNA in saliva for the evaluation of genetic risk to common diseases, prediction of response to commonly used drugs, and diagnosis of genetic diseases, enabling patients with personalized diagnosis and helping them avoid adverse drug effects and promote healthier lifestyles.

Cloud Dentistry, LLC operates a cloud-based platform that facilitates real-time connections between dental offices and dental staff. Founded in 2014 and based in Humble, Texas, the company provides a digital platform and mobile application that enables dental practices to message and book staff on demand. The platform allows users to hire professionals, book specialists, submit patient histories and x-rays, and utilize direct messaging for coordination. By streamlining the staffing process, Cloud Dentistry helps dental practices fill short-term staffing gaps and access top talent efficiently, ultimately saving time and costs associated with hiring.

Dondoctor is a company that offers an online scheduling platform designed specifically for medical centers, clinics, and hospitals. The platform aims to streamline operations by providing a user-friendly and standardized interface, along with a dedicated web portal for each healthcare provider. It features appointment reminders and automatic confirmations, which help minimize missed appointments and facilitate quicker, self-managed scheduling. By enhancing the scheduling process, dondoctor enables healthcare organizations to boost profitability, improve operational efficiency, and elevate patient satisfaction.

Aesyra SA designs and manufactures medical devices named AesyBite that monitors and relieves sleep bruxism. The company was founded in 2017 and is based in Lausanne, Switzerland.

Dermafence develops an innovative technology for the treatment of energy-mediated skin injuries and burns. Its devices are a kind of liquid bandages that form a thin layer on skin upon application and prevent the progression of wounds after burns following the absorption of any kind of energy that include thermal, mechanical, radiation, and laser-mediated burn injuries. It was founded in 2017 and is based in Jerusalem, Yerushalayim, Israel.

Air Doctor Ltd. operates an online marketplace that connects travelers with verified medical practitioners while they are abroad. Founded in 2016 and based in Motza Illit, Israel, the platform allows users to easily find and book appointments with a diverse range of healthcare providers, including doctors, dentists, emergency clinics, pharmacies, and labs. By providing access to thousands of trusted professionals across various specialties, Air Doctor not only facilitates medical consultations for travelers but also helps practitioners expand their visibility and clientele. This service aims to enhance the healthcare experience for individuals in unfamiliar locations by simplifying the process of finding and accessing medical care.

DermaDiagnostics mission is to provide a non-invasive dermal patch platform for healthcare facilities’ use in diagnosing of sexually transmitted infections (STIs) and cervical cancer. ​Their products allow doctors and healthcare workers to appropriately test in a non-invasive way by providing faster, same-day results, and easier patient-centered diagnosing in the area of gynecologic health.

Resthetics provides anesthetic recycling services. The company was founded in 2015 and is based in Austin, Texas.

DocFlight operates a telemedicine platform to connect doctors with the patients. Its platform allows users to speak to a doctor or get opinion on their medical records. The company offers video consultation, translation of medical records, and triage service by physician case manager, as well as written medical reports with patient summary, confirmed diagnosis, treatment recommendations, and action items. DocFlight was founded in 2016 and is based in New York, New York.

Purple Dental is a medical device startup improving dental experience through patient centered design. Their first product is called Tori. It is a tooth isolation and moisture control device. Its simplistic design helps dentists make procedures faster, safer and more comfortable. Even though Tori works for any dental treatment, it excels in pediatric dentistry, providing a solution far superior than any other competitor.

MediPrint is a Mexico City-based company focused on creating customized high-tech medical solutions through 3D printing technology. Collaborating with medical professionals and institutions, the company develops a variety of products, including rehabilitation braces, orthopedic insoles, supports for dental prostheses, and anatomical models for medical use. MediPrint also engages in individual projects, offering personalized services to clients interested in their innovative developments. Additionally, the company operates a division called 3DPlus, which extends its 3D printing capabilities beyond healthcare to produce prototypes, molds, and custom objects for various applications. By making advanced 3D printing technology accessible, MediPrint aims to enhance patient care and provide tailored solutions in the medical field.

Every day more than 1 million implants are placed into human and animal bodies using open surgery. Lumigbo has developed a technology to build up implants inside the body using an access channel of less than half a millimeter in diameter. The procedure can be used for almost any type of implant. We have developed minimally viable prototypes for neurovascular, orthopedic and dental applications. Currently, we are improving our prototypes and expect to close round A in the third quarter of 2018.

Masi-Epoxi is a formulation that contains epoxy resins and a load of mineral salts. Its initial semi-solid consistency allows its molding with great efficiency and without presenting heat generation that could be harmful to the patient's tissues.

People of any age can benefit from orthodontic treatment. Teeth that are crooked, crowded, or that stick out affect the way your teeth look and work. These changes improve not only the look of your smile, but the health and longevity of your teeth. A referral from your general dentist is not required to be seen at our office, however they are welcomed. Their practice consists of young children, adolescence and adult patients. They feel privliged to have the opportunity to get to know them while they help shape their smile and improve their lives. In general, orthodontic treatment time ranges from 18-24 months. The actual time can depend on the growth of your mouth and face, your cooperation in your treatment, and the severity of the problem.

Adhesys Medical specializes in the development and manufacture of innovative polyurethane-based surgical adhesives designed for diverse applications both on the skin and internally. Their products utilize a unique polyurethane technology that distinguishes them from existing options in terms of ease of use, flexibility, biodegradability, and performance in wet environments. These advanced surgical sealants aim to enhance surgical procedures, improve patient comfort, and ultimately save lives by providing effective and reliable solutions for healthcare professionals.

LightForce Orthodontics addresses this problem by applying patented, next-generation manufacturing technology adapted for use in orthodontic treatment by the industry's leading experts. It enables orthodontists to utilize its 3D-printing technology to create custom braces for each individual patient, significantly reducing the number of adjustment visits needed.

uSonik is designed to clean all your teeth in seconds.

Granta is a dream of a group of talented people with the vision of helping the disadvantaged and making a positive change. They provide a high-end solution, to design and manufacture a faster, cheaper, exact and personalised implant for every patient, making possible to have an aesthetical result that facilitates their reinsertion to society. Annually more than 30k people experience this problem in Mexico, of which 90% are from the public health sector which is over saturated & could be benefited.

Dognostica is an innovative screening company that offers low cost, highly accurate, non-invasive tests for different types of diseases, initially the most common cancers. The system harnesses dogs' proven ability to detect cancer, enhanced by proprietary measurements. The founders have developed a novel patent-protected, process which offers higher reproducibility and productivity whilst ensuring high welfare standards for the dogs. Building on the founders' expertise, who have more than 40 years combined experiences, in handling dogs, working with world-leading security units dealing with explosives and drugs, the team has developed ways to address the hurdles which have prevented others from turning dogs' noses into reliable disease screening tools.

Doya Medical focuses on developing a noninvasive delivery technology aimed at treating otitis media with effusion. The company's innovative eStent technology facilitates the drainage of fluid from the middle ear without the need for surgical intervention. By enabling patients to naturally drain fluid and supporting the body's anatomical functions, Doya Medical's approach minimizes the need for ear tube surgery, offering a less invasive alternative to traditional treatment methods.

Virtudent, Inc. is a Boston-based company founded in 2014 that specializes in providing on-site dental services for employees at their workplaces. The company offers essential preventative dental care, including cleanings, X-rays, dental sealants, and fluoride varnish application, through innovative pop-up clinics. Utilizing telehealth technologies, Virtudent brings dental professionals directly to employees, enhancing access to dental care. This service is designed for corporations and organizations, allowing them to improve healthcare benefits for their employees while promoting preventative dental care in a convenient manner.

DCDI changes the uncomfortable and time consuming current dentures impression technique, which is a major pain and involves physical elastic impression materials, proposing a quick and elegant optical solution. This is a unique solution for a multi-billion $ market.

Oral cancer patients often suffer from debilitating damage to healthy tissue during treatment. OralSave's radiation delivery device aims to protect healthy oral tissue, allowing for non surgical, pinpoint radiation therapy with no need for a specially trained maxillofacial prosthodontist. The device is patient-specific and manufactured rapidly using 3D printing. For patients around the world, this could result in retaining the ability to eat, taste, swallow and produce saliva.

Disease Diagnostic Group (DDG) is a pre-revenue medical device company specializing in the development of rapid, accurate, and inexpensive disease diagnostic tests.

3Derm Systems, Inc. is a Boston-based company focused on enhancing dermatological care through innovative imaging technology. Founded in 2011, it provides a handheld skin imager and cloud-based software that enables users, including non-dermatologists, to capture high-resolution 3D images of skin lesions. This system allows patients to monitor their skin conditions from home, significantly reducing the need for frequent in-office visits, which can be both costly and inconvenient. By facilitating remote reviews of these images by trained dermatologists, 3Derm ensures timely monitoring of potential skin cancers and other skin issues. This approach not only cuts down on wait times but also helps manage the healthcare resources more efficiently. The company's mission is to improve access to dermatological care and provide a cost-effective solution that empowers patients while maintaining high diagnostic standards. As of August 2020, 3Derm operates as a subsidiary of Digital Diagnostics, Inc.

3Derm Systems, Inc. is a Boston-based company focused on enhancing dermatological care through innovative imaging technology. Founded in 2011, it provides a handheld skin imager and cloud-based software that enables users, including non-dermatologists, to capture high-resolution 3D images of skin lesions. This system allows patients to monitor their skin conditions from home, significantly reducing the need for frequent in-office visits, which can be both costly and inconvenient. By facilitating remote reviews of these images by trained dermatologists, 3Derm ensures timely monitoring of potential skin cancers and other skin issues. This approach not only cuts down on wait times but also helps manage the healthcare resources more efficiently. The company's mission is to improve access to dermatological care and provide a cost-effective solution that empowers patients while maintaining high diagnostic standards. As of August 2020, 3Derm operates as a subsidiary of Digital Diagnostics, Inc.

Dimples is a company focused on helping organizations and individuals reduce printing costs and environmental impact through innovative ink and toner conservation solutions. The company has developed a patented method that creates unique perforation overlays, known as 'dimples,' which are applied to fonts. This technology allows users to maintain the visual integrity of printed text while significantly decreasing ink and toner consumption. By offering engineering-focused software and font overlays, Dimples enables newspapers, magazines, and other organizations to utilize their existing fonts, effectively promoting cost savings and sustainability in the printing process.

LittleBonsai is a product studio that is dedicated to creating fun and useful household products in a responsible way. They’ve developed ReBrush™, an exciting new toothbrush that features replaceable heads and high-quality handles made from aluminum and sustainably grown hardwood.

Guided Surgery Solutions, LLC specializes in the design, manufacture, and sale of 3D image-based surgical guides specifically for dental implant surgery. The company's flagship product, the ThinLayer Drill Guide System, was developed to address design limitations in existing surgical guides and aims to make guided surgery both technically and economically feasible for dental surgeons. By providing these innovative solutions, Guided Surgery Solutions enables dental professionals to enhance their surgical precision and improve patient outcomes. Established in 2009, the company is headquartered in Wellesley, Massachusetts, and serves a diverse clientele of dental surgeons and laboratories.

Diagnostics For All is a NPO that develops diagnostics for health and agricultural purposes.