Bill & Melinda Gates Foundation

BioSurfaces is a provider of medical care services intended to be offered by augmenting existing and emerging medical approaches with nanotechnology. The company's services applies room-temperature electrospinning process to allow drug loading into each fiber, providing a reservoir for sustained drug release at the implant site, enabling customers to make devices and coatings as thin as 10um which can treat diseases at site.

Sail Biomedicines is a flagship pioneering company that is developing tomorrow's medicines today using life's language. Sail's platform combines first-in-class translatable circular RNA technology (Endless RNATM or eRNA) with unique programmable nanoparticles based on natural components to thoroughly program medications for the first time.

MIP Discovery is a technology leader specializing in the development of molecularly imprinted polymers (MIPs) and nanoMIPs, which are plastic antibodies designed to address the limitations of traditional MIP manufacturing methods. The company's innovations feature polymers and antibodies that incorporate a single binding site for specific targets, allowing them to be effectively fused to solid substrates, such as sensor surfaces. This capability provides hospitals with highly effective reagents suitable for a variety of applications, including point-of-care diagnostics and field-based testing, thereby enhancing the efficiency and accuracy of medical testing.

Evolve Biosystems, Inc. is a biotechnology company based in Davis, California, focused on developing and marketing probiotic-based biotherapeutics aimed at establishing, restoring, and maintaining a healthy human microbiome. The company specializes in addressing gut dysbiosis across the human life cycle, particularly in newborns during their first six months of life. Evolve Biosystems utilizes a platform that combines specific probiotic bacteria with prebiotic oligosaccharides to create effective delivery systems. Their products include consumer-directed solutions for home use as well as specialized formulations for neonatal intensive care units. In addition to human health, the company also applies its discovery platform to address similar microbiome issues in production animals. Evolve Biosystems was incorporated in 2011.

Novavax, Inc. is a late-stage biotechnology company focused on the discovery, development, and commercialization of vaccines aimed at preventing serious infectious diseases. Its lead vaccine candidates include ResVax, designed to protect infants from respiratory syncytial virus (RSV) through maternal immunization, and NanoFlu, targeted at treating seasonal influenza in older adults. Both candidates utilize Novavax's proprietary Matrix-M adjuvant to enhance immune responses. In addition, the company is advancing an RSV F vaccine for older adults and children, and it is developing nanoparticle vaccines against the Ebola virus and a combination respiratory vaccine for influenza and RSV. Novavax is also working on a COVID-19 vaccine, NVX-CoV2373, in collaboration with Takeda Pharmaceutical Company for development and commercialization. Established in 1987 and headquartered in Gaithersburg, Maryland, Novavax utilizes its recombinant technology platform to create highly immunogenic nanoparticles to address urgent global health needs.

Ceres Nanosciences Inc. is a privately held life sciences company focused on the development and commercialization of innovative sample preparation products utilizing its proprietary Nanotrap® technology. This technology captures, enriches, and preserves analytes and biomarkers, which is essential for the early detection of diseases such as cancer, cardiac conditions, and infectious diseases. By facilitating the identification of low abundance biomarkers, Ceres aims to enhance diagnostic accuracy and improve patient outcomes while potentially reducing healthcare costs. The company has a diverse product pipeline that includes advanced sample collection technologies and diagnostics, supported by federal grants and industry collaborations. Among its key developments is a direct antigen test for Lyme disease, which is anticipated to be available for commercial use.

BlueWillow Biologics, a clinical-stage biopharmaceutical company based in Ann Arbor, Michigan, specializes in the development of intranasal vaccines and anti-infective products utilizing its patented nanotechnology platform. The company's innovative NanoStat vaccine technology incorporates a unique oil-in-water nanoemulsion, allowing for the effective delivery and adjuvant of various antigens. BlueWillow focuses on vaccines for respiratory and sexually transmitted diseases, including pertussis, pandemic influenza, anthrax, and HIV, as well as providing NanoBio Protect, a nasal antiseptic solution. The company also has a licensing agreement with Merck for the use of its adjuvant in intranasal vaccines for respiratory syncytial virus (RSV) and seasonal influenza. Founded in 1999 as a spin-off from the University of Michigan, BlueWillow Biologics aims to enhance mucosal immunity through its advanced vaccine technology.