Big Brain Holdings

Founded in 2021, Big Brain Holdings is a venture capital firm based in Los Angeles, California. It focuses on investing in early-stage companies operating in the blockchain, fintech, and web3 sectors.
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https://signal.nfx.com/firms/***

Jorge Cantera

Investor

River Fields

Analyst

Thomas Helm

Venture Partner

Sam Kim

General Partner

Kavita Singh

Analyst

Tom Weber

Analyst

Jonathan Wong

Analyst

Past deals in Trading Platform

Vest

Venture Round in 2025
Vest Labs is in the process of developing an advanced financial exchange specifically designed for digital assets.

Mavryk Dynamics

Venture Round in 2025
Mavryk Dynamics simplifies trading real-world assets (RWA) and using decentralized finance (DeFi).

Zkasino

Series A in 2024
ZKasino is a technology company that specializes in developing decentralized gambling platforms for online gaming. Its core product is a hyperchain infrastructure layer designed for on-chain gaming, which allows users to bet directly using their cryptocurrency wallets, eliminating the need for traditional processes such as Know Your Customer (KYC) procedures, user sign-ups, and deposits or withdrawals. This platform enables seamless, intermediary-free online betting experiences.

BitFlow Finance

Pre Seed Round in 2024
BitFlow Finance offers bitcoines to trade while utilizing the capital,network, and security of Layer 1 Bitcoin, by eliminating middlemen and intermediaries.

Saturn

Pre Seed Round in 2023
Saturn is a decentralized Bitcoin exchange that enhances peer-to-peer non-custodial orderbooks and provides a secure trading experience.

Stix.co

Seed Round in 2023
Stix is the largest OTC platform for secondary market liquidity for Digital Assets

Cube Group

Seed Round in 2023
Cube Group is a hybrid CEX-DEX digital asset marketplace that addresses the challenges of traditional centralized exchanges and decentralized finance platforms. The company provides a user-centric design, radical transparency, safety, and liquidity, with features like multi-party compute, on-chain settlement, proof-of-reserves, and multi-chain support. Its vaults represent users' balances on their respective layer-one blockchains, offering transparent liquidation standards and criteria for derivatives and margin trading. The platform also standardizes market data and order sessions, allowing seamless onboarding for market participants through web interfaces for trading.

Lumina

Seed Round in 2023
Lumina is a zero-knowledge, KYC-enabled, enterprise-ready DEX on Mina.

Tensor Labs

Seed Round in 2023
Tensor Labs is the creator of: Tensor Trade (tensor.trade) - Solana's Leading NFT Marketplace for pro traders Vector (vector.fun) - Multiplayer onchain trading

Jumbo

Venture Round in 2022
Jumbo operates a decentralized finance exchange platform that facilitates the buying and selling of cryptocurrencies. By leveraging blockchain technology, the company aims to lower the entry barriers for trading, allowing users to engage in various financial activities such as swaps, liquidity pooling, farming, and staking. Their platform features an interface that enables users to configure asset parameters and detect liquidity pools, ultimately enhancing the investment experience and improving potential returns for investors.

Panoptic

Seed Round in 2022
Panoptic is a blockchain-based options trading platform that facilitates trustless, permissionless, and composable options products. It enables instant settlement and oracle-free trading on the Ethereum blockchain, catering to various strategies within the decentralized finance (DeFi) ecosystem.

Ultrade

Seed Round in 2022
Ultrade develops a DeFi trading platform on the Algorand blockchain and enables projects to launch branded, non-custodial exchanges with shared liquidity. It offers a whitelabel, bridgeless cross-chain order-book solution for spot and perpetual trading, supporting native asset trading across multiple chains without bridges. The platform provides an admin panel and APIs and operates on a revenue-sharing model, allowing crypto projects and communities to run custom exchanges with full ownership and unified liquidity, while reducing the cost and complexity of building scalable DeFi trading apps by removing the need to write low-level order-book or matching-engine code.

Fig Investments

Pre Seed Round in 2022
Fig Investments is a technology platform that enables banks, portfolio managers, and broker-dealers to offer crypto-structured and direct indexing products to their high-net-worth clients through a white-label solution.

SithSwap

Seed Round in 2022
SithSwap is a company that operates an advanced Automated Market Maker (AMM) on the StarkNet platform. It specializes in providing instant swaps for both volatile and stable assets with minimal slippage and near-zero fees. The company's services are designed to offer trading pairs similar to Uniswap V2, with configurable trading fees and no administrative fees. Additionally, SithSwap incorporates built-in flash loan capabilities and leverages the full security of Ethereum, allowing traders to earn incentives for participating in governance decisions regarding future protocol emissions.

Vertex Protocol

Seed Round in 2022
Vertex Protocol is a decentralized FX trading platform.

swap.net

Angel Round in 2022
Swap.net is a developer of an NFT aggregator and exchange platform that provides aggregated liquidity across various marketplaces. The platform enables users to search for notable collections and tokens across different blockchain markets, facilitating cross-market arbitrage and the execution of limit orders for collections treated as liquid assets. By allowing users to identify the most competitive offers for any token, Swap.net enhances the accessibility and efficiency of NFT transactions, catering to the evolving needs of the digital asset community.

Yanda

Convertible Note in 2022
Yanda develops an automated cryptocurrency trading platform that aims to empower users with financial control while reducing overhead. The platform features a simple interface for configuring and customizing trading strategies alongside built-in trading facilities, enabling users to tailor cryptocurrency trading to respond efficiently to market trends.
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