Big Brain Holdings

Founded in 2021, Big Brain Holdings is a venture capital firm based in Los Angeles, California. It focuses on investing in early-stage companies operating in the blockchain, fintech, and web3 sectors.

Jorge Cantera

Investor

Sam Kim

General Partner

Kavita Singh

Analyst

Tom Weber

Analyst

Jonathan Wong

Analyst

Past deals in Ethereum

Decent Land Labs

Seed Round in 2024
Decent Land Labs focuses on resolving the on-chain storage issue. It aims to optimize EVM-compatible storage to encourage developers to use on-chain tools for every stack layer, thereby extending the lifespan of dApps.

Eywa

Seed Round in 2024
Eywa is a decentralized cross-chain protocol designed to facilitate the transfer of liquidity and data across various blockchains that support smart contracts. By addressing interoperability challenges, Eywa aims to create a seamless ecosystem for decentralized finance (DeFi) applications. The protocol serves as a middle layer, enabling developers to build cross-chain decentralized applications and engage in cross-chain farming. This functionality allows users to easily perform cross-chain swaps and bridge assets across different DeFi platforms. Eywa's approach enhances the accessibility and utility of existing DeFi blockchains, fostering innovation and collaboration within the cryptocurrency space.

Obscuro Labs

Venture Round in 2024
Obscuro Labs develops TEN, a Layer 2 rollup that scales and encrypts Ethereum, allowing smart contracts to contain both public and private elements without changing the user or developer experience. The TEN protocol operates contracts at larger scale and supports on-chain gaming, smart contract sharing, sealed token auctions, data encryption, and the deployment of tokenized rewards, while also enabling components such as artificial intelligence agents to function within the ecosystem.

Initia Labs

Seed Round in 2024
Initia is a network for 0-to-1 omnichain rollups built by fusing a novel L1 with an interwoven application-specific L2 infrastructure system. The Initia Platform provides product ready rollups that enables teams to build scalable and sovereign systems while eliminating the UX complexities end users face when interacting with a modular multi-chain universe. Initia’s ownership of the full tech stack allows for a suite of chain-level mechanisms that align the economic interests across users, developers, L2 app chains, and the L1. Initia's initial launch products include an all-in-one portal for accessing core tools of the ecosystem, a Omnitia-ecosystem focused wallet for navigating between the L2s, a block explorer that supports InitiaVM transactions and developer tooling, and a Market Minitia that allows users to trade NFTs and create AI-generated NFT collections through prompts.

zkLink

Seed Round in 2023
zkLink is a blockchain infrastructure company offering a multi-chain trading platform that unifies blockchain networks and addresses Ethereum fragmentation through aggregated rollups. Its solutions use zero-knowledge proofs to enable secure cross-chain transactions and to aggregate liquidity from isolated networks, supporting high-throughput decentralized applications. The platform provides customizable rollup architectures, including app-specific options, to unify tokens and liquidity across Ethereum Layer 2s and to give developers cost- and performance-efficient interoperability.

Panoptic

Seed Round in 2022
Panoptic is a blockchain-based options trading platform that facilitates trustless, permissionless, and composable options products. It enables instant settlement and oracle-free trading on the Ethereum blockchain, catering to various strategies within the decentralized finance (DeFi) ecosystem.

SithSwap

Seed Round in 2022
SithSwap is a company that operates an advanced Automated Market Maker (AMM) on the StarkNet platform. It specializes in providing instant swaps for both volatile and stable assets with minimal slippage and near-zero fees. The company's services are designed to offer trading pairs similar to Uniswap V2, with configurable trading fees and no administrative fees. Additionally, SithSwap incorporates built-in flash loan capabilities and leverages the full security of Ethereum, allowing traders to earn incentives for participating in governance decisions regarding future protocol emissions.

Zoksh Pay

Venture Round in 2022
Zoksh Pay offers a non-custodial, permissionless payment platform built on Solana. It enables users and merchants to receive payments in various cryptocurrencies, fiat currencies via zRamp aggregator, and stablecoins from major EVM chains. All transactions settle instantly in USDC on Solana, ensuring speed, security, and reliability.

Yanda

Convertible Note in 2022
Yanda develops an automated cryptocurrency trading platform that aims to empower users with financial control while reducing overhead. The platform features a simple interface for configuring and customizing trading strategies alongside built-in trading facilities, enabling users to tailor cryptocurrency trading to respond efficiently to market trends.

Eywa

Seed Round in 2022
Eywa is a decentralized cross-chain protocol designed to facilitate the transfer of liquidity and data across various blockchains that support smart contracts. By addressing interoperability challenges, Eywa aims to create a seamless ecosystem for decentralized finance (DeFi) applications. The protocol serves as a middle layer, enabling developers to build cross-chain decentralized applications and engage in cross-chain farming. This functionality allows users to easily perform cross-chain swaps and bridge assets across different DeFi platforms. Eywa's approach enhances the accessibility and utility of existing DeFi blockchains, fostering innovation and collaboration within the cryptocurrency space.

CyberBox

Seed Round in 2022
CyberBox is the first NFT Marketplace with ReFi integration on the Celo blockchain. Our vision is to build a marketplace to support every NFT collection and every ReFi project that looks to create impact with NFTs and build their communities around them and promote the value of sustainability and climate protection.

Decent Land Labs

Seed Round in 2022
Decent Land Labs focuses on resolving the on-chain storage issue. It aims to optimize EVM-compatible storage to encourage developers to use on-chain tools for every stack layer, thereby extending the lifespan of dApps.

Ludex

Pre Seed Round in 2018
Ludex is a developer of a web3 gaming protocol that enables video game developers to integrate on-chain token transactions and smart contracts into games using APIs and SDKs, without requiring blockchain expertise. The platform also facilitates creating, organizing, and participating in tournaments and matches where prizes can be won, thereby making blockchain-based contract functionality accessible to gamers.
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