ACF Investors

Veremark Ltd is a London-based company that specializes in online reference and background checking software solutions. Founded in 2018, it offers a comprehensive platform that enables businesses to verify candidates' credentials, including employment history, academic qualifications, and various background checks such as criminal, credit, and global sanctions checks. The platform also includes features like psychometric assessments and adverse media checks, ensuring compliance with regulations such as GDPR and PDPA. With additional offices in the Philippines and Singapore, Veremark aims to facilitate the hiring of qualified and trustworthy employees through its automated screening processes.

Neurovalens Limited specializes in the development of non-invasive neurostimulation medical devices aimed at addressing global health challenges such as obesity. Founded in 2013 and headquartered in Ballymena, United Kingdom, the company offers products like Stimu Slim and Modius, which are electronic headsets designed to influence brain activity and support weight management. Neurovalens employs advanced technologies to activate specific brain regions, enabling adjustments in autonomic function and neuro-metabolic processes. The company has received funding from Invest NI as part of the European Union’s Investment for Growth and Jobs Programme to support its research and development initiatives, enhancing its competitiveness in the field of neuroscience and bioscience.

Spotta Ltd is a company that specializes in developing smart pest control systems aimed at the hotel and lodging industry, focusing on the early detection of bed bugs. Founded in 2018 and headquartered in Cambridge, United Kingdom, Spotta offers a battery-powered insect monitoring sensor that alerts users to potential bed bug infestations. This innovative technology analyzes detection data to ensure that notifications pertain only to genuine incidents, allowing hotels to proactively prevent bed bugs from spreading and facilitating more efficient and cost-effective treatment options. By leveraging these systems, lodging providers can enhance guest satisfaction and maintain a pest-free environment.

BirdsEyeView is a London-based InsurTech venture functioning as a Managing General Agent. The company addresses the growing challenges posed by climate change, particularly the increasing frequency and severity of natural disasters. By utilizing advanced aerial intelligence, BirdsEyeView simplifies the collection and analysis of geospatial data. It leverages meteorological information from satellites, ground stations, and IoT devices to develop innovative parametric insurance solutions for climate-related risks. Their proprietary rating engine enables precise pricing of insurance at the individual farm level, allowing agricultural insurers to make informed decisions more rapidly.

Oxford Medical Simulation Ltd. specializes in providing virtual reality (VR) simulation-based training solutions for healthcare professionals, including doctors and nurses. Founded in 2017 and headquartered in London, with an additional office in Boston, the company offers immersive VR scenarios that allow users to manage patient care in a realistic environment. These simulations enable healthcare workers to perform investigations, initiate treatment, and collaborate with their team, all while receiving objective feedback on their performance. This feedback highlights strengths, team management skills, and areas for improvement. By offering a customizable and evidence-based approach, Oxford Medical Simulation aims to make high-quality medical training more accessible and cost-effective, addressing the challenges of traditional simulation methods that can be expensive and limited in scope.

Veremark Ltd is a London-based company that specializes in online reference and background checking software solutions. Founded in 2018, it offers a comprehensive platform that enables businesses to verify candidates' credentials, including employment history, academic qualifications, and various background checks such as criminal, credit, and global sanctions checks. The platform also includes features like psychometric assessments and adverse media checks, ensuring compliance with regulations such as GDPR and PDPA. With additional offices in the Philippines and Singapore, Veremark aims to facilitate the hiring of qualified and trustworthy employees through its automated screening processes.

Konsileo Limited is a commercial insurance broker based in London, United Kingdom, founded in 2015. The company utilizes an innovative online platform that includes features such as Fact Find and Risk Hub, which facilitate efficient data capture and regulatory compliance. This technology allows brokers to streamline their operations, providing them with more time to focus on client relationships. Konsileo's approach promotes collaboration among brokers by fostering a community-oriented environment that prioritizes professional support and expertise sharing, rather than a traditional hierarchical structure. The platform also offers clients easy access to information regarding premiums, policy duration, and downloadable insurance documents, enhancing the overall risk management experience.

Spirea Ltd. is a healthcare technology company based in Harrogate, United Kingdom, that specializes in developing antibody drug conjugates (ADCs) for cancer treatment. Founded in 2015, Spirea has created a smart polymer platform designed for the controlled delivery of drug combinations, thereby maximizing the clinical efficacy of therapies. The company's innovative approach to ADCs allows for a greater amount of drug payload to be specifically targeted to tumor cells, resulting in enhanced therapeutic effects while significantly minimizing side effects. This development enables healthcare providers to offer well-tolerated treatment options for a variety of cancers, ultimately aiming to improve the quality of life for patients.

Monterosa Productions Ltd specializes in audience interaction technology, offering a cloud platform that enhances engagement for content creators and developers across various media. The company provides a suite of products that facilitate live games, voting, competitions, and sports experiences, specifically designed for television shows and events. Its key offerings include LViS for television, a scalable interaction platform with embeddable applications; LViS for brands, which integrates interactive content across multiple screens; and LViS for sports, enabling audience participation through tracking, voting, and gaming. Monterosa collaborates with prominent clients in the entertainment and sports sectors, such as the BBC, ITV, and the English Premier League, to create immersive experiences that boost audience interactivity and loyalty. With a foundation established in 2003 and offices in London, Liverpool, and Minsk, the company boasts a team of experts dedicated to delivering reliable and innovative interactive solutions.

BLOK is one of London’s leading boutique class based gyms, combining fitness with art, design, and fashion.

Designed by seasoned capital markets professionals, HUBX empowers investment professionals to manage their workflows and relationships with insight, intelligence and control. HUBX provides an out of the box solution for advisors to manage deals from origination to distribution. Suitable for: • Brokers and Deal Introducers • Investment Syndicates • Wealth managers and Private Banks • Corporate Finance Advisors • Investment Banks • Stock Exchanges HUBX technology powers the London Stock Exchange Group’s ELITE private placement platform connecting high growth companies with LSEG’s global institutional investor network. Regulated by the FCA.

Veremark Ltd is a London-based company that specializes in online reference and background checking software solutions. Founded in 2018, it offers a comprehensive platform that enables businesses to verify candidates' credentials, including employment history, academic qualifications, and various background checks such as criminal, credit, and global sanctions checks. The platform also includes features like psychometric assessments and adverse media checks, ensuring compliance with regulations such as GDPR and PDPA. With additional offices in the Philippines and Singapore, Veremark aims to facilitate the hiring of qualified and trustworthy employees through its automated screening processes.

SnapDragon Monitoring Limited is a company based in Edinburgh, United Kingdom, that specializes in brand protection software solutions. Established in 2014, it offers both managed and self-service options to help businesses safeguard their brand reputations. One of its key products is Swoop, a software designed specifically for brand protection. By focusing on small and medium-sized enterprises, SnapDragon Monitoring aims to create a safer marketplace for consumers while supporting the growth of businesses.

Kuano Ltd specializes in developing quantum and AI solutions aimed at molecular design, particularly in the fields of drug discovery and development. Founded in 2020 and based in London, the company integrates quantum simulation with machine learning to create effective enzyme inhibitors. Its innovative discovery platform employs target quantum mapping alongside AI-driven chemistry, facilitating the faster and more efficient development of superior drug candidates. Kuano's technology is applicable across several sectors, including pharmaceuticals, crop protection, and industrial chemistry, ultimately enhancing the quality of new therapeutics while reducing the time required for their discovery.

VenueScanner operates as a two-sided marketplace focused on facilitating venue search and booking for event organizers. The platform caters to a wide range of events, from meetings to yoga sessions and parties, addressing the challenges of discovering and booking venues online. With over 14,000 venues listed, organizers can easily find, favorite, inquire, and book spaces directly, without intermediaries, through a user-friendly interface. VenueScanner also serves as a digital marketing tool for venue hosts, enabling them to promote their under-utilized spaces. The platform allows venues to list themselves in just five minutes, contributing to a more efficient and cost-effective booking process. With a data-led approach, VenueScanner operates in major cities across the UK, including London, Edinburgh, and Manchester, making it a valuable resource in the events industry. Founded by experienced professionals in e-commerce and digital marketing, the company aims to enhance the consumer experience in venue booking.

Micrima Limited is a company based in Bristol, United Kingdom, specializing in the development and commercialization of advanced imaging technology for early breast cancer detection. The firm has created an ergonomic imaging system branded as MARIA, which employs microwave radar technology to provide non-ionizing imaging services. This system features a horizontal couch and a hemispherical scanning head designed to accommodate various breast sizes without the need for breast compression, offering a more comfortable experience for patients. Micrima is also focused on developing algorithms for processing the data collected during imaging. Initially spun out from research at the University of Bristol, the company has conducted extensive laboratory validation of its technology and is currently conducting human use trials. Micrima primarily serves breast cancer imaging centers and healthcare providers across the UK, aiming to provide a painless and efficient alternative for routine breast cancer screening.

AdaptTech is a biomedical company based in Birmingham, United Kingdom, that specializes in developing innovative wearable technologies aimed at enhancing the quality of life for individuals with physical disabilities. Founded in 2015, the company offers a range of products designed to assist clinicians in achieving better socket fitting and monitoring for patients who have lost a lower limb. Key offerings include the INSIGHT Scanner, which quickly creates a three-dimensional model of prosthetic sockets, the INSIGHT Wearable that collects real-time biometric data, and the INSIGHT App that provides users with easy access to their results. Through these advancements, AdaptTech seeks to improve the overall experience and outcomes for those relying on lower limb prosthetics.

Spotta Ltd is a company that specializes in developing smart pest control systems aimed at the hotel and lodging industry, focusing on the early detection of bed bugs. Founded in 2018 and headquartered in Cambridge, United Kingdom, Spotta offers a battery-powered insect monitoring sensor that alerts users to potential bed bug infestations. This innovative technology analyzes detection data to ensure that notifications pertain only to genuine incidents, allowing hotels to proactively prevent bed bugs from spreading and facilitating more efficient and cost-effective treatment options. By leveraging these systems, lodging providers can enhance guest satisfaction and maintain a pest-free environment.

Neurovalens Limited specializes in the development of non-invasive neurostimulation medical devices aimed at addressing global health challenges such as obesity. Founded in 2013 and headquartered in Ballymena, United Kingdom, the company offers products like Stimu Slim and Modius, which are electronic headsets designed to influence brain activity and support weight management. Neurovalens employs advanced technologies to activate specific brain regions, enabling adjustments in autonomic function and neuro-metabolic processes. The company has received funding from Invest NI as part of the European Union’s Investment for Growth and Jobs Programme to support its research and development initiatives, enhancing its competitiveness in the field of neuroscience and bioscience.

Scoota is an online advertising technology company that enables advertisers to create, activate, measure and optimise brilliant brand campaigns at scale. We offer a single programmatic platform for the creation and delivery of rich, high-impact formats via open real-time bidding and private marketplaces, without compromising creative execution or brand safety. Our technology includes a unique campaign delivery system that pre-reads an ad space in real-time so that the right creative is delivered into the right ad unit without the need for pre-testing and independent site integration. We care about and invest in an open and long-term approach, enabling partners to work with us through integration with their own systems of choice, or via our platform whether as a self-serve solution, or a fully managed service. Scoota was founded in London in 2008 and employs more than 40 people. In 2015, we won best overall programmatic technology at The Drum Digital Trading Awards and Silver for Best Ad Tech Provider at the 2015 British Media Awards.

Qube is a provider of private studio and co-working spaces tailored for content creators. It offers access to 30 purpose-built studios designed for music, podcasting, photography, and video editing. The flagship location in West London spans 16,000 square feet and was inaugurated in February 2020. By creating a collaborative environment, Qube enables its members to share resources and connect with other creatives, facilitating the professional writing, production, and recording processes. The space is specifically crafted to support the needs of inspired creators, fostering an atmosphere where they can thrive.

Autologyx Ltd. is a company based in Farnborough, United Kingdom, that specializes in developing cloud-based applications aimed at automating complex business processes. Founded in 2011 and originally known as NowWeComply Limited before rebranding in 2017, Autologyx offers a no-code digital operations platform designed for various industries, with a particular emphasis on the legal and professional services sectors. The platform enables users to create, modify, and deploy tailored workspaces, facilitating the automation of tasks ranging from simple to intricate processes. It integrates seamlessly with third-party systems, allowing for efficient management of claims, asset management, compliance, and governance. By providing a comprehensive solution that displaces traditional point solutions, Autologyx addresses the unique challenges of legal and compliance workflows.

Neurovalens Limited specializes in the development of non-invasive neurostimulation medical devices aimed at addressing global health challenges such as obesity. Founded in 2013 and headquartered in Ballymena, United Kingdom, the company offers products like Stimu Slim and Modius, which are electronic headsets designed to influence brain activity and support weight management. Neurovalens employs advanced technologies to activate specific brain regions, enabling adjustments in autonomic function and neuro-metabolic processes. The company has received funding from Invest NI as part of the European Union’s Investment for Growth and Jobs Programme to support its research and development initiatives, enhancing its competitiveness in the field of neuroscience and bioscience.

Micrima Limited is a company based in Bristol, United Kingdom, specializing in the development and commercialization of advanced imaging technology for early breast cancer detection. The firm has created an ergonomic imaging system branded as MARIA, which employs microwave radar technology to provide non-ionizing imaging services. This system features a horizontal couch and a hemispherical scanning head designed to accommodate various breast sizes without the need for breast compression, offering a more comfortable experience for patients. Micrima is also focused on developing algorithms for processing the data collected during imaging. Initially spun out from research at the University of Bristol, the company has conducted extensive laboratory validation of its technology and is currently conducting human use trials. Micrima primarily serves breast cancer imaging centers and healthcare providers across the UK, aiming to provide a painless and efficient alternative for routine breast cancer screening.

BMLL Technologies Ltd. is a financial data company based in London, established in 2014. It operates a cloud-based platform that provides advanced analytics and historical data specifically for capital market participants. The platform utilizes machine learning and inference frameworks to analyze limit order book data from various global financial markets, enabling clients to gain insights into market behavior and forecast price movements. BMLL offers immediate access to standardized Level 3 data, which includes the trading intentions of all market participants, along with pre and post-trade analytics. This service is particularly beneficial for investment banks, hedge funds, asset managers, and academic institutions, allowing them to conduct tasks such as order book simulation, back-testing, risk assessment, and compliance measurement without the need to purchase or curate their own data. BMLL's Data Science as a Service platform is designed for flexibility and scalability, providing users with extensive computational resources and a comprehensive historical record of detailed order book data across various asset classes.

BMLL Technologies Ltd. is a financial data company based in London, established in 2014. It operates a cloud-based platform that provides advanced analytics and historical data specifically for capital market participants. The platform utilizes machine learning and inference frameworks to analyze limit order book data from various global financial markets, enabling clients to gain insights into market behavior and forecast price movements. BMLL offers immediate access to standardized Level 3 data, which includes the trading intentions of all market participants, along with pre and post-trade analytics. This service is particularly beneficial for investment banks, hedge funds, asset managers, and academic institutions, allowing them to conduct tasks such as order book simulation, back-testing, risk assessment, and compliance measurement without the need to purchase or curate their own data. BMLL's Data Science as a Service platform is designed for flexibility and scalability, providing users with extensive computational resources and a comprehensive historical record of detailed order book data across various asset classes.

VenueScanner operates as a two-sided marketplace focused on facilitating venue search and booking for event organizers. The platform caters to a wide range of events, from meetings to yoga sessions and parties, addressing the challenges of discovering and booking venues online. With over 14,000 venues listed, organizers can easily find, favorite, inquire, and book spaces directly, without intermediaries, through a user-friendly interface. VenueScanner also serves as a digital marketing tool for venue hosts, enabling them to promote their under-utilized spaces. The platform allows venues to list themselves in just five minutes, contributing to a more efficient and cost-effective booking process. With a data-led approach, VenueScanner operates in major cities across the UK, including London, Edinburgh, and Manchester, making it a valuable resource in the events industry. Founded by experienced professionals in e-commerce and digital marketing, the company aims to enhance the consumer experience in venue booking.

Limejump Limited is an energy technology company based in London, United Kingdom, specializing in the development and operation of a Virtual Power Plant (VPP) platform. Founded in 2012, Limejump provides optimized access to the energy market for customers with electricity-generating or consuming assets. Its platform integrates various components, including cloud-based software, smart devices, and analytical tools, to connect and optimize asset performance. Limejump offers products such as the Balancing Mechanism, which aids the National Grid in managing electricity supply and demand, as well as Power Purchase Agreements (PPAs) to enhance the value of electricity generation. Additionally, the company facilitates participation in demand response programs, allowing generators to adjust energy output and businesses to modify their energy consumption, thereby supporting grid stability. As of early 2019, Limejump operates as a subsidiary of The Shell Petroleum Company Limited.

Neurovalens Limited specializes in the development of non-invasive neurostimulation medical devices aimed at addressing global health challenges such as obesity. Founded in 2013 and headquartered in Ballymena, United Kingdom, the company offers products like Stimu Slim and Modius, which are electronic headsets designed to influence brain activity and support weight management. Neurovalens employs advanced technologies to activate specific brain regions, enabling adjustments in autonomic function and neuro-metabolic processes. The company has received funding from Invest NI as part of the European Union’s Investment for Growth and Jobs Programme to support its research and development initiatives, enhancing its competitiveness in the field of neuroscience and bioscience.

Form3 is a London-based company that provides cloud-based payment processing, clearing, and settlement services tailored for regulated financial institutions. Established in 2016, it offers a fully managed payment technology service built on a robust AWS cloud processing platform. Form3's architecture includes multiple payment gateways and a micro-services framework, allowing clients to access a comprehensive range of payment schemes through a single application programming interface (API). This technology facilitates secure and reliable agency payment services on a per-transaction basis without upfront costs. Its clientele consists of various financial entities, including leading banks, non-bank financial institutions, and fintech companies, such as payment institutions and e-money providers.

Vantage Power Ltd. specializes in designing and manufacturing electric and hybrid systems for buses and heavy-duty vehicles. Founded in 2011 and based in London, the company provides a range of hybrid and electric powertrain solutions, including hybrid battery systems, drive systems, range extenders, and custom battery solutions. Vantage Power focuses on retrofitting existing buses with hybrid powertrains, allowing operators to significantly reduce fuel consumption and emissions without the high costs associated with acquiring new hybrid vehicles. The company's engineering team, which includes experts from the heavy-duty vehicle, Formula 1, and aerospace sectors, is dedicated to creating innovative solutions that ensure optimal performance, fuel efficiency, and reliability. Additionally, Vantage Power offers technologies related to system design, telemetry, control systems, and battery management. As of 2019, Vantage Power operates as a subsidiary of Allison Transmission Holdings, Inc.

Exonate is a privately held, early stage, biotech company spun out of the University of Nottingham that is focused on alternative splicing of Vascular Endothelial Growth Factor (VEGF) in ophthalmology. Exonate’s lead programme is focused on Diabetic Macular Oedema (DMO). A consequence of diabetic retinopathy, DMO, is swelling in an area of the retina called the macula and wet Age-Related Macular Degeneration (wAMD), which is the leading cause of vision loss in people aged 60 and older. The Company is founded on scientific excellence with strong links to Professor David Bates and his lab at Nottingham University specializing in the biology and biochemical pathways of VEGF splice variants. Exonate have developed small molecules that inhibit production of pro-angiogenic VEGF through selective inhibition of serine/threonine-protein kinase 1 (SRPK1)-mediated VEGF splicing. These inhibitors have already demonstrated superior efficacy as topical agents in preclinical models of wet AMD. Through a Wellcome Trust funded project, Exonate has completed an optimization programme and has nominated a pre-clinical candidate drug with optimal characteristics. During the second quarter of 2020 regulatory toxicology and safety pharmacology studies have taken place. This is to support the successful application to the regulatory authorities for clinical evaluation. Exonate is led by an experienced, international management team that has previously worked together with cross-disciplinary experience in medicine and drug development, as well as successful fundraising for early stage companies. About Diabetic Macular Oedema (DMO)*: DMO is the build-up of fluid (Oedema) in a region of the retina called the macula. The macula is important for the sharp, straight-ahead vision that is used for reading, recognizing faces, and driving. DMO is the most common cause of vision loss among people with diabetic retinopathy. About half of all people with diabetic retinopathy will develop DMO and although it is more likely to occur as diabetic retinopathy worsens, DMO can happen at any stage of the disease. About wet Age-Related Macular Degeneration (wet AMD): Today, wet AMD is a leading cause of vision loss in people aged 60 years or older and affects more than 30 million patients worldwide, over 200,000 of those in the UK alone. If untreated patients are likely to lose sight in the affected eye within 24 months of disease onset. The main currently available treatment options for DMO and wet AMD are: • anti-VEGF antibody drugs – to prevent the growth of new blood vessels in the eye. Unlike small molecule drugs or eye drops these treatments must be injected into the eye once every 1 or 2 months. Resistance can develop to these drugs causing the disease to progress anew. • Laser surgery – to destroy abnormal blood vessels in the eye. This type of surgery is only suitable if blood vessel damage is not too extensive and if the abnormal blood vessels aren't close to the fovea, as performing surgery close to this part of the eye can cause permanent vision loss. • With DMO, Corticosteroids either injected or implanted into the eye, may be used alone or in combination with other drugs or laser surgery to treat DMO. *source: https://nei.nih.gov/health/diabetic/retinopathy

Keit Ltd. specializes in the design and manufacture of advanced spectrometers and related instruments that operate across a spectrum from ultraviolet to far infrared rays. Established in 2012 and based in Didcot, United Kingdom, the company focuses on innovative applications for its products, which include the measurement of signal levels, vibrations, and various substances in both gas and liquid forms. One of Keit's flagship products is the microFTS®, a compact and rugged Fourier Transform Infrared (FTIR) spectrometer originally developed for space applications. This device sets a new benchmark for real-time liquid-state analyses and serves industries such as pharmaceuticals, chemicals, oil and gas, and food and beverage, where performance in extreme environments is crucial.

City Pantry is an online marketplace where users can discover interesting food for next event. City Pantry is on a mission to rid the world of egg mayonnaise triangles, stale sandwiches and vol-au-vents by disrupting the (slightly boring) world of traditional corporate catering. Working with the best independent chefs, street vendors, specialist caterers, restaurants, and supper clubs in London, City Pantry makes it easy to cater office lunches, meetings, and events.

Saberr Limited, established in 2013 and based in London, United Kingdom, specializes in predicting startup success through advanced mathematics and psychology algorithms. The company offers innovative software designed to enhance workplace dynamics by providing tools for managers to build trust, improve team performance, and streamline collaboration. Its platform features online surveys that analyze working relationships, as well as resources for one-on-one meetings and team interactions. By focusing on developing leadership capabilities and adapting to agile and remote work environments, Saberr aims to support organizations in optimizing their performance and fostering effective teamwork.

Monterosa Productions Ltd specializes in audience interaction technology, offering a cloud platform that enhances engagement for content creators and developers across various media. The company provides a suite of products that facilitate live games, voting, competitions, and sports experiences, specifically designed for television shows and events. Its key offerings include LViS for television, a scalable interaction platform with embeddable applications; LViS for brands, which integrates interactive content across multiple screens; and LViS for sports, enabling audience participation through tracking, voting, and gaming. Monterosa collaborates with prominent clients in the entertainment and sports sectors, such as the BBC, ITV, and the English Premier League, to create immersive experiences that boost audience interactivity and loyalty. With a foundation established in 2003 and offices in London, Liverpool, and Minsk, the company boasts a team of experts dedicated to delivering reliable and innovative interactive solutions.

Exonate is a privately held, early stage, biotech company spun out of the University of Nottingham that is focused on alternative splicing of Vascular Endothelial Growth Factor (VEGF) in ophthalmology. Exonate’s lead programme is focused on Diabetic Macular Oedema (DMO). A consequence of diabetic retinopathy, DMO, is swelling in an area of the retina called the macula and wet Age-Related Macular Degeneration (wAMD), which is the leading cause of vision loss in people aged 60 and older. The Company is founded on scientific excellence with strong links to Professor David Bates and his lab at Nottingham University specializing in the biology and biochemical pathways of VEGF splice variants. Exonate have developed small molecules that inhibit production of pro-angiogenic VEGF through selective inhibition of serine/threonine-protein kinase 1 (SRPK1)-mediated VEGF splicing. These inhibitors have already demonstrated superior efficacy as topical agents in preclinical models of wet AMD. Through a Wellcome Trust funded project, Exonate has completed an optimization programme and has nominated a pre-clinical candidate drug with optimal characteristics. During the second quarter of 2020 regulatory toxicology and safety pharmacology studies have taken place. This is to support the successful application to the regulatory authorities for clinical evaluation. Exonate is led by an experienced, international management team that has previously worked together with cross-disciplinary experience in medicine and drug development, as well as successful fundraising for early stage companies. About Diabetic Macular Oedema (DMO)*: DMO is the build-up of fluid (Oedema) in a region of the retina called the macula. The macula is important for the sharp, straight-ahead vision that is used for reading, recognizing faces, and driving. DMO is the most common cause of vision loss among people with diabetic retinopathy. About half of all people with diabetic retinopathy will develop DMO and although it is more likely to occur as diabetic retinopathy worsens, DMO can happen at any stage of the disease. About wet Age-Related Macular Degeneration (wet AMD): Today, wet AMD is a leading cause of vision loss in people aged 60 years or older and affects more than 30 million patients worldwide, over 200,000 of those in the UK alone. If untreated patients are likely to lose sight in the affected eye within 24 months of disease onset. The main currently available treatment options for DMO and wet AMD are: • anti-VEGF antibody drugs – to prevent the growth of new blood vessels in the eye. Unlike small molecule drugs or eye drops these treatments must be injected into the eye once every 1 or 2 months. Resistance can develop to these drugs causing the disease to progress anew. • Laser surgery – to destroy abnormal blood vessels in the eye. This type of surgery is only suitable if blood vessel damage is not too extensive and if the abnormal blood vessels aren't close to the fovea, as performing surgery close to this part of the eye can cause permanent vision loss. • With DMO, Corticosteroids either injected or implanted into the eye, may be used alone or in combination with other drugs or laser surgery to treat DMO. *source: https://nei.nih.gov/health/diabetic/retinopathy

Creo Medical Limited is a medical device manufacturer based in Chepstow, South Wales, specializing in the research and development of electrosurgical devices for surgical endoscopy. Established in 2003 and originally known as MicroOncology Ltd, the company focuses on innovative technologies that enhance surgical procedures. One of its key products is the Speedboat RS2, which integrates bipolar radiofrequency and microwave energy into a single platform for various applications, including tissue dissection, resection, ablation, and coagulation. Creo Medical operates from a modern facility equipped with controlled manufacturing areas, including a Class 6 Cleanroom, to support its research and development efforts.

Limejump Limited is an energy technology company based in London, United Kingdom, specializing in the development and operation of a Virtual Power Plant (VPP) platform. Founded in 2012, Limejump provides optimized access to the energy market for customers with electricity-generating or consuming assets. Its platform integrates various components, including cloud-based software, smart devices, and analytical tools, to connect and optimize asset performance. Limejump offers products such as the Balancing Mechanism, which aids the National Grid in managing electricity supply and demand, as well as Power Purchase Agreements (PPAs) to enhance the value of electricity generation. Additionally, the company facilitates participation in demand response programs, allowing generators to adjust energy output and businesses to modify their energy consumption, thereby supporting grid stability. As of early 2019, Limejump operates as a subsidiary of The Shell Petroleum Company Limited.

Family Traveller Limited operates an online portal designed to assist families in planning vacations with children of all ages. Founded in 2009 and based in London, the company provides comprehensive resources that include destination guides, travel tips, and recommendations for family-friendly accommodations and activities. Catering to parents traveling with babies, children, and teenagers, Family Traveller covers a wide array of travel options, from UK breaks to long-haul holidays. The platform aims to be a one-stop resource for practical advice and insights, ensuring families can make informed decisions for enjoyable trips. Additionally, the company publishes a magazine that offers further insights into various travel destinations worldwide.

City Pantry is an online marketplace where users can discover interesting food for next event. City Pantry is on a mission to rid the world of egg mayonnaise triangles, stale sandwiches and vol-au-vents by disrupting the (slightly boring) world of traditional corporate catering. Working with the best independent chefs, street vendors, specialist caterers, restaurants, and supper clubs in London, City Pantry makes it easy to cater office lunches, meetings, and events.

Isotera, UK-based LED lighting specialist. Led by CEO Marc Ottolini, Isotera has developed an intelligent LED lighting system which is designed to improve the performance of LED lights, and makes installation more affordable. The company is now working in partnership with players in the global lighting supply chain to offer end to end solutions to contractors and system integrators.

Creo Medical Limited is a medical device manufacturer based in Chepstow, South Wales, specializing in the research and development of electrosurgical devices for surgical endoscopy. Established in 2003 and originally known as MicroOncology Ltd, the company focuses on innovative technologies that enhance surgical procedures. One of its key products is the Speedboat RS2, which integrates bipolar radiofrequency and microwave energy into a single platform for various applications, including tissue dissection, resection, ablation, and coagulation. Creo Medical operates from a modern facility equipped with controlled manufacturing areas, including a Class 6 Cleanroom, to support its research and development efforts.

Sophia Search Limited is a company that has developed an innovative ambient e-commerce platform designed to seamlessly connect written content with e-commerce transactions. Founded in 2007 and headquartered in Belfast, UK, the platform utilizes advanced content analytics to help consumers discover relevant products in real time while browsing online. By linking web content to associated products, Sophia Search enhances the shopping experience without compromising consumer privacy through invasive tracking methods. The solution benefits publishers, brands, and retailers by enabling them to significantly increase their revenues through higher engagement and click-through rates. In addition to its Belfast headquarters, the company has offices in San Francisco and St. Petersburg, Russia, and operates as a subsidiary of Aiqudo, Inc. since 2017.

MSPEX Diagnostics Ltd was founded in 2011 as a spinoff of the University of Glamorgan, in South Wales, with the aim to develop markets and applications for Ion Mobility Spectrometry Technology in clinical research, clinical diagnostics, food and environmental analysis. Through its acquisition of GAS GmbH in January 2013, IMSPEX secured access to World leading IMS technology and to a range of equipment which is market ready for customer applications. Over 2013 the group formed by IMSPEX and GAS has established relationships and provided instruments to a range of blue chip companies, research hospitals and research centres and universities.

Destiny Pharma is a clinical-stage biotechnology company based in Brighton, United Kingdom, specializing in the discovery and development of innovative antimicrobial medicines aimed at treating infectious diseases. The company is advancing several drug candidates, including XF-73 Nasal, currently in Phase II trials for preventing post-surgical staphylococcal infections, and XF-73 Dermal, which is in Phase I trials for treating skin infections caused by antibiotic-resistant bacteria. Additionally, Destiny Pharma is developing XF-70 for conditions such as ventilator-associated pneumonia and cystic fibrosis, along with DPD-207 for bacterial and fungal eye infections. The company collaborates with various academic institutions and organizations, including the University of Southampton and China Medical System Holdings Limited, to explore new treatments for infections associated with antibiotic resistance. Destiny Pharma's focus on unique mechanisms of action for its XF series presents potential solutions in addressing the growing global healthcare challenge of drug-resistant bacteria.

Concepta is a United Kingdom start-up that is developing a new all-in-one device for pregnancy and fertility testing and monitoring.

Ebury is a financial services company that specializes in supporting small and medium-sized businesses in international trade. It offers an integrated platform that facilitates cross-border payments, risk management, and funding, allowing companies to make and receive payments in over 100 currencies. Clients benefit from competitive exchange rates, the ability to hedge currency risk, and access to emerging market currencies. Ebury also provides white-label products through brokers and accountants, enhancing its service offerings. With a workforce of more than 170 employees across its offices in London, Madrid, and Amsterdam, Ebury serves a client base of over 3,000 mid-sized companies. The company is regulated by the Financial Conduct Authority.

Affectv is an advertising technology company that runs media campaigns for global brands. It offers services to improve the relevancy of online advertisements for consumers and advertisers. The company provides a technology that analyses what users do and share them across social media sites from tailor advertisements to users based on their interests. It reaches over 500 million people and is extracting actionable data signals from billions of digital interactions. These signals are used to deliver the most advanced form of advertising, SignalAds. SignalAds are personal messages delivered to a relevant person, on a relevant device, at a relevant point in real time. It allows brands to engage more effectively with new and existing customers as well as optimize ROI. Affectv was founded on January 3, 2011 and is headquartered in London, United Kingdom.

Ezbob Ltd., operating under the name ezbob, specializes in providing small business lending services throughout the United Kingdom. The company offers unsecured business loans to support various needs, including equipment purchases, inventory acquisition, staffing, marketing initiatives, and cash flow management. Founded in 2011 and headquartered in London, ezbob allows clients to apply for and receive funding at any time via internet-connected devices. The company caters to a diverse range of industries, including retail, wholesale, hospitality, real estate, eCommerce, and dental services. In addition to its direct lending services, ezbob has developed a proprietary Core Lending Platform that enables financial institutions to enhance their lending capabilities and transition to digital services. This platform has attracted partnerships with major banks such as Santander and NatWest, further establishing ezbob's presence in the financial sector.

YPlan uncovers the best events every day so you can get out and Live Your City. Get the lowdown on cool dates, hidden culture and where to hang with friends. Discover, book, go – it's that simple. Flash your YPlan ticket and you're in. Founded in London in February, 2012, YPlan works directly with 3500+ event partners worldwide, has over 1.5 million users, and 1000+ 5* reviews on App Store.

Adpoints is a digital media and data company that rewards individuals for watching and engaging with video advertisements. Utilizing proprietary proof of viewing technology, Adpoints ensures that advertisers' videos are fully viewed, thereby addressing viewer avoidance and enhancing brand engagement. The company uniquely connects ad viewership data to in-store purchases, allowing FMCG advertisers to assess the impact of their campaigns on sales and gain valuable insights into return on investment. In partnership with the Nectar loyalty scheme in the UK, Adpoints offers consumers the opportunity to earn points without requiring any purchases, transforming viewers from passive recipients to active participants. Founded in 2010 by Jason Froggett and his colleagues, the company has established itself in the advertising sector with a distinctive rewards-based model that fosters deep viewer engagement. Adpoints is recognized for its innovative approach, which has minimal direct competition, and is led by chairman Terry Hunt, a veteran in direct marketing with significant industry credentials.

Ventive Ltd. is a company based in London, United Kingdom, that specializes in designing, developing, and installing heat recovery ventilation systems for homes with chimneys. Established in 2011, Ventive focuses on both existing buildings and new construction projects. The company has created innovative passive ventilation systems that utilize heat recovery technology, allowing for the introduction of fresh air while minimizing energy costs. By optimizing each system to meet the specific needs of occupants, Ventive aims to reduce carbon emissions and alleviate fuel poverty, contributing to a more sustainable built environment.

Trident Energy Limited is an independent developer of technology for the offshore renewable energy sector, specializing in linear generators that convert sea wave motion into electricity. Founded in 2003 and based in London, the company has created the PowerPod, a patented and cost-effective solution that simplifies the process of harnessing energy from waves. This technology integrates standard solid-state power electronics to control the generator and produce usable electrical power. PowerPod can be utilized as a power take-off system in various Wave Energy Converters and oscillating hydrofoil tidal stream devices. Additionally, Trident is developing a small wave energy generator that can be attached to existing offshore infrastructure, providing autonomous off-grid power and reducing reliance on diesel generators, thereby minimizing environmental risks. By offering a modular and generic solution for the offshore renewable energy market, Trident Energy aims to collaborate with partners to enhance next-generation offshore wind foundations and promote sustainable energy solutions.

Langtons Gin Limited, established in 2011 and located in Carlisle, United Kingdom, specializes in the production of gin and sells its products online. The brand embodies the essence of the Lake District, characterized by a soft aroma of juniper complemented by floral notes. Langtons No.1 gin offers a soft and fresh flavor profile, featuring citrus notes and a hint of sweetness, culminating in a smooth finish. The gin is crafted using pure water and a blend of 11 botanicals, including ancient Lake District oak bark, which contribute to its brightness and depth. It is versatile enough to be enjoyed with tonic, in cocktails, or on its own with ice.

Bactest Limited is a company based in Cambridge, United Kingdom, focused on developing innovative microbial contamination testing technologies for various applications, including wastewater management, industrial microbiology, and laboratory settings. The company has created CYTOMAIA, a respirometer technology platform that effectively monitors microbial processes by translating sensitive pressure changes into meaningful data. This technology enables the measurement of microbial respiration rates, addressing critical needs for microbial monitoring across diverse sectors such as environmental, food, veterinary, and clinical microbiology. Founded in 2001, Bactest aims to provide automated solutions that enhance safety and efficiency in microbial testing, particularly in environments where centralized services may be insufficient.

OR Productivity PLC, a medical robotics company, focuses on the development and commercialization of surgical robotics to healthcare providers and hospitals. The company develops Freehand, a robotic camera controller for laparoscopic or keyhole surgery. Its Freehand system provides surgeons with improved quality and control of visualization during keyhole procedures. The company markets its technology through a network of distributors in the United Kingdom and internationally. OR Productivity PLC was founded in 2010 and is based in Guildford, the United Kingdom with additional offices in the United States.

Upad Limited is an online property letting agency based in London, UK, and was founded in 2008 by James Davis. The company serves as a platform for landlords, offering a range of services that include property and room listings, floor planning, photography, gas safety certification, energy performance certification, property management, tenant referencing, and insurance. Upad stands out as the UK's largest online letting agency and has successfully assisted over 12,500 landlords in letting more than 30,000 properties, equivalent to the output of a 60-branch high street agency. By leveraging technology, Upad enables landlords to advertise their properties on major platforms such as Zoopla and Rightmove within 24 hours, typically generating around 35 tenant inquiries. Their competitive pricing allows landlords to access these services for just £120, significantly lower than traditional agency fees. Upad's commitment to customer service is reflected in high customer loyalty, with many clients providing referrals and returning for additional services. Research indicates that landlords using Upad experience notably fewer rent arrears compared to those who do not.

Ezbob Ltd., operating under the name ezbob, specializes in providing small business lending services throughout the United Kingdom. The company offers unsecured business loans to support various needs, including equipment purchases, inventory acquisition, staffing, marketing initiatives, and cash flow management. Founded in 2011 and headquartered in London, ezbob allows clients to apply for and receive funding at any time via internet-connected devices. The company caters to a diverse range of industries, including retail, wholesale, hospitality, real estate, eCommerce, and dental services. In addition to its direct lending services, ezbob has developed a proprietary Core Lending Platform that enables financial institutions to enhance their lending capabilities and transition to digital services. This platform has attracted partnerships with major banks such as Santander and NatWest, further establishing ezbob's presence in the financial sector.

Mporium Group Plc is a technology company based in London that specializes in providing software as a service and related support services across the United Kingdom and Europe. The company operates the IMPACT platform, which leverages signals from diverse sources—including television, electronic program guides, sports, social media, and RSS feeds—to optimize the pricing, timing, and selection of advertising messages. Formerly known as MoPowered Group Plc, Mporium Group was incorporated in 2013 and rebranded in 2015. With a strong focus on mobile technology, Mporium aims to enhance revenue for merchants by integrating data-driven marketing solutions that span various digital channels. Its acquisition of Fast Web Media, a marketing agency with over 20 years of experience, has broadened its product offerings, while a strategic partnership with Cxense provides advanced analytics capabilities. Mporium has collaborated with prominent retail brands, positioning itself as a leader in mobile, eCommerce, and marketing industries.

CrowdVision is a leading automated pedestrian analytics and insights company. CrowdVision software shows what is happening to an entire pedestrian population, in real time. This enables infrastructure operators like airports, transport hubs, retail malls, convention centres and theme parks to act decisively to increase efficiency and profitability, both in the moment and in the future, whilst improving their customers’ experience. The CrowdVision solution processes live video input from commercial off the shelf cameras, and detects pedestrian movements automatically using sophisticated artificial intelligence techniques. CrowdVision outputs live data about everything from flows, queues and wait times to processing times, occupancies, and asset utilisation. Live dashboards reveal actionable insights to improve real-time operations, whilst accumulated historical data provides reliable evidence for planning and investment decisions. CrowdVision is headquartered in London, with regional offices in Dubai, Melbourne, and New York. More information is available at crowdvision.com.

Enval Limited specializes in the design and manufacture of recycling equipment and modular plants that utilize microwave-induced pyrolysis for recycling plastic-aluminium laminates. Founded in 2005 as a spin-out from the Department of Chemical Engineering at the University of Cambridge, the company addresses environmental and regulatory challenges across various sectors, including industrial, commercial, and municipal markets. Enval provides expert solutions that transform waste into valuable resources, catering to waste handlers, local authorities, fast-moving consumer goods brands, and individual consumers. In addition to its proprietary recycling technology, the company offers environmental life cycle analysis and technology consultancy, focusing on the pyrolytic recycling of complex flexible packaging materials. Enval's innovative approach aims to create sustainable alternatives to landfills by extracting commercially usable aluminum, oil, and gas from materials such as drink cartons and toothpaste tubes. Based in Huntingdon, United Kingdom, Enval is committed to advancing recyclability and promoting a circular economy.

PlayJam Ltd. is a technology company based in London, specializing in the development and delivery of software-as-a-service (SaaS) solutions for embedded gaming and rich media on Android-powered TVs, set-top boxes, and other devices. The company focuses on providing interactive gaming content to users globally, operating a built-for-TV games platform that powers casual games on over 90 million Smart TV devices. PlayJam also designs and develops white-label over-the-top (OTT) devices, including gamepads and customized controllers, that integrate various downloadable and streaming services. Additionally, the company offers Nexad, an HTML5 mobile advertising solution that facilitates ad design and delivery. Incorporated in 1997, PlayJam aims to make affordable gaming accessible to families through partnerships with leading TV and set-top box manufacturers.