MB Venture Partners

SweetBio, Inc. is a medical device company based in Memphis, Tennessee, specializing in the research, development, and manufacturing of innovative wound care solutions. Founded in 2015, the company focuses on bioengineering membranes that utilize medical-grade Manuka honey to enhance healing and combat infections associated with wounds, pressure ulcers, diabetic ulcers, surgical wounds, and abrasions. SweetBio's unique honey-incorporated absorbable membranes are designed to improve the efficacy of wound care treatments, offering healthcare professionals a new platform for addressing both chronic and acute wounds effectively.

Cast21 is a medical product developer based in Memphis, Tennessee, focused on creating innovative orthopedic solutions for fracture and joint care. Established in 2015, the company has developed a waterproof and breathable cast designed to enhance patient comfort and facilitate recovery. Its unique design not only allows for skin hygiene—enabling patients to wash and scratch beneath the cast—but also supports the integration of electronic therapies aimed at reducing healing time. By prioritizing user experience and effective treatment, Cast21 seeks to improve the overall recovery process for individuals with orthopedic injuries.

Spine Wave, Inc. is a manufacturer of medical devices focused on the treatment of spinal disorders. Founded in 2001 and based in Shelton, Connecticut, the company develops and markets a range of innovative products aimed at providing surgical solutions for spine surgeons and their patients. Its offerings include expandable PEEK spacers, interbody devices for posterior surgery, pivoting and lateral spacer systems, and the GraftMag Graft Delivery System for bone graft delivery. Additionally, Spine Wave produces fixation products designed for addressing degeneration, deformity, tumors, and trauma in the thoracolumbar spine, as well as anterior cervical plate systems for spinal fusion from C2-C7 and cervical spacer systems for degenerative disc disease from C2-T1. The company distributes its products through a network of distributors, emphasizing a surgeon-driven approach to product development to address real surgical challenges.

Lineus Medical specializes in medical devices aimed at enhancing vascular access and preventing complications associated with intravenous (IV) therapy. The company's flagship product, the SafeBreak Vascular device, employs patented break-away technology that allows for a controlled separation in the IV tubing when excessive tension is applied. This innovation helps prevent dislodgement of access lines, reducing the risks of blood loss and infection, and ultimately improving the overall quality of care for patients undergoing IV treatment. By focusing on the safety and effectiveness of IV therapy, Lineus Medical addresses a critical aspect of patient care in healthcare settings.

SweetBio, Inc. is a medical device company based in Memphis, Tennessee, specializing in the research, development, and manufacturing of innovative wound care solutions. Founded in 2015, the company focuses on bioengineering membranes that utilize medical-grade Manuka honey to enhance healing and combat infections associated with wounds, pressure ulcers, diabetic ulcers, surgical wounds, and abrasions. SweetBio's unique honey-incorporated absorbable membranes are designed to improve the efficacy of wound care treatments, offering healthcare professionals a new platform for addressing both chronic and acute wounds effectively.

Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

Restore Medical Solutions is a medical device company focusing on products and techniques that promote SSI reduction, safety, and productivity within healthcare. The company manufactures a sterilization tray system that reduces the risk of infection from contaminated medical instruments. Its modular sterilization tray systems reduce the potential risk of infection from contaminated instruments and enable surgical departments to improve the quality of care while reducing cost. Founded in 2012, Restore Medical Solutions is headquartered in Memphis, Tennessee.

Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

EndoInSight was founded to help reduce the terrible toll Colorectal Cancer (CRC) takes on society by providing clinicians with a cost-effective method for reducing the pain and discomfort associated with colonoscopy-based CRC screening. While inflating the colon is necessary to enhance visibility during colonoscopy, trapped air can leave patients feeling bloated and uncomfortable for hours following their procedure. It has long been known that using CO2 to inflate the colon can dramatically reduce post-procedural pain and discomfort yet adoption of the technique has been slow due to a lack of awareness concerning the benefits of CO2 and the capital expenditure related with current CO2 insufflation systems.

CrossRoads Extremity Systems is a medical device manufacturing company that specializes in engineering foot and ankle implant systems. Using technology and materials, like high compression nitinol, our products are optimal for surgery. It was founded in 2014 and headquartered in Memphis, Tennessee.

Zyga Technology, Inc. is a medical device company focused on developing and commercializing minimally invasive products for underserved conditions of the lumbar spine. The company offers the SImmetry Sacroiliac Joint Fusion System, which provides a surgical solution for sacroiliac joint fusion, addressing issues such as joint disruptions and degenerative sacroiliitis. Additionally, Zyga is working on the Glyder Facet Restoration System, an investigational device aimed at treating chronic facetogenic pain. Founded in 2008 and based in Minnetonka, Minnesota, Zyga Technology has assembled a skilled team with extensive experience in the spine industry. As of late 2017, Zyga operates as a subsidiary of RTI Surgical, Inc.

EcoSurg™ (pronounced eek-oh-surj) is a developer of environmentally-friendly surgical supplies that is dedicated to reducing the carbon footprint of the surgical suite. Their flagship product is the EcoSurg™ line of Patient Positioners. Disposable patient positioners are used in over 20 Million surgical procedures per year in the United States alone. These foam shapes are used to properly position patients in a variety of positions, ensuring safety, comfort, and adequate access to the surgical site. When disposed of, however, these products are harmful to the environment as they are made from materials that consist largely of petroleum-based derivatives. These compounds and the other hazardous byproducts from their production are not only harmful to the environment, but also incur higher handling and disposal costs that are inevitably passed on to the Customer.

Innometrix began with the goal of translating the science of biomechanics into clinical solutions for female pelvic floor disorders. Innometrix is innovating diagnosis and treatment of female pelvic floor disorders. These debilitating disorders are alarmingly common. 50% of all women who have given birth will have a pelvic floor disorder in their lifetimeand costing $27 billion each year. Current treatments are mostly surgical, and there is a great degree of art and intuition involved in diagnosing and treating these patients. Moreover, these surgeries have had undesirably high complication and revision rates. Innometrix is creating device solutions to solve problems facing the clinicians who treat these disorders. Their goal is to improve treatment outcomes, and increase patient satisfaction in a field that needs innovation.

Blood Monitoring Solutions, Inc. is dedicated to developing innovative blood monitoring systems aimed at reducing blood wastage. Based in Memphis, Tennessee, the company has created a smart blood transport system that enables blood banks to continuously monitor the temperature and integrity of each blood unit. This proactive, data-driven approach not only enhances patient safety but also helps hospitals minimize costs associated with blood spoilage. By ensuring that blood is stored within the appropriate temperature range, the company's solutions allow for longer preservation of blood supplies, ultimately supporting more effective transfusion practices in healthcare settings.

CamPlex is a U.S.-based company founded in 2012 and headquartered in Germantown, Tennessee, specializing in the healthcare industry. The company focuses on manufacturing high-quality fiber optic products designed to enhance performance and extend signal transmission capabilities. CamPlex offers innovative fiber optic-based camera adapter systems and broadcast-grade interface gear, which help broadcast professionals streamline signal delivery and improve operational efficiency. By providing these solutions, CamPlex aims to reduce operating costs and eliminate the necessity for additional components and costly replacements.

Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.

Hubble Telemedical is dedicated to enabling earlier detection of systemic and debilitating diseases that manifest in the retina - the light-sensitive membrane at the back of the eye that transmits visual information to the brain - for more effective treatment and patient care. In addition to eye diseases such as retinopathy, macular degeneration and glaucoma, a range of systemic diseases such cardiovascular and immune diseases can be detected in the retina. Early diagnosis is essential for effective treatment of these diseases. Unfortunately, many at-risk individuals do not receive annual retinal exams due to inconvenience or unavailability. The result is that many individuals go undiagnosed until severe damage has occurred, causing medical complications and increased healthcare costs. They are changing that paradigm. Thanks to their proprietary, award-winning Telemedical Retinal Image Analysis and Diagnosis (TRIAD™) technology, Hubble Telemedical enables screening and diagnosis where and when it is most convenient for the healthcare consumer. They partner with healthcare providers, insurance companies, and employers to bring the power of retinal screening to the consumer. Their services are fully HIPAA-compliant, secure, and easy to use –- and multi-site, peer-reviewed and published clinical studies have demonstrated their ability to dramatically increase annual screening compliance, thereby decreasing overall healthcare costs and, most importantly, improving patients' health. They invite you to contact us to learn more about their services and technology— and how they can work with you to bring the power of retinal image analysis to your organization.

Restore Medical Solutions is a medical device company focusing on products and techniques that promote SSI reduction, safety, and productivity within healthcare. The company manufactures a sterilization tray system that reduces the risk of infection from contaminated medical instruments. Its modular sterilization tray systems reduce the potential risk of infection from contaminated instruments and enable surgical departments to improve the quality of care while reducing cost. Founded in 2012, Restore Medical Solutions is headquartered in Memphis, Tennessee.

Hapten Sciences, Inc. is a privately-held biopharmaceutical company based in Memphis, Tennessee, established in 2010. The company focuses on the identification and development of early-stage products aimed at improving global health outcomes. One of its key innovations is PDC-APB, a vaccine designed to prevent contact dermatitis resulting from exposure to urushiol oil found in poison ivy, poison oak, and poison sumac. This product aims to provide patients with a solution to avoid allergic reactions without side effects, thereby contributing significantly to the well-being of individuals affected by these plants.

Mobilizer Inc. is a company that specializes in the development of innovative six-wheeled holsters designed for medical equipment, aimed at enhancing the efficiency of patient ambulation in healthcare settings. Modeled after a wheeled walker, these holsters feature shelves and attachments that facilitate the transportation of equipment necessary for the mobility of critical care patients. By improving the process of medical ambulation, Mobilizer aims to enhance patient well-being while streamlining operations within hospitals. The company is a graduate of the ZeroTo510 medical device startup accelerator, further validating its commitment to advancing healthcare solutions.

BioNanovations is a medical technology company focused on the rapid diagnosis of bacterial infections, particularly Staphylococcus infections. Currently, diagnosing these infections takes 3 to 5 days, which can be critical due to the aggressive nature of certain strains that may lead to severe health consequences, including limb amputation or death within 48 hours. To address these challenges, BioNanovations is developing a handheld diagnostic platform that significantly reduces the testing time to under 30 minutes. This integrated real-time diagnostic solution enables healthcare professionals to quickly analyze blood, sputum, urine, and cerebrospinal fluid, facilitating immediate access to vital diagnostic information. By providing real-time data on bacterial infections, the platform not only improves patient outcomes by reducing morbidity and mortality rates but also supports healthcare professionals and agencies in tracking epidemiological trends effectively.

Focal Point Pharmaceuticals is a healthcare company focused on pharmaceutical businesses. It was incorporated in 2013 and is based in Memphis, Tennessee, United States.

Better Walk Inc. is an innovative company that specializes in the design and development of crutches. Established in 2013 and headquartered in Atlanta, Georgia, the company aims to improve traditional crutch technology by alleviating pressure from the underarm area and minimizing direct force on the wrist of users. Better Walk's commitment to innovation is a fundamental aspect of its culture, which was further strengthened during its participation in the Zero To 510 accelerator in Memphis, where it secured early venture funding. In late 2014, the company shifted its focus to finalizing the Better Walk crutch, positioning itself for production and an anticipated product launch in early 2015.

EcoSurg™ (pronounced eek-oh-surj) is a developer of environmentally-friendly surgical supplies that is dedicated to reducing the carbon footprint of the surgical suite. Their flagship product is the EcoSurg™ line of Patient Positioners. Disposable patient positioners are used in over 20 Million surgical procedures per year in the United States alone. These foam shapes are used to properly position patients in a variety of positions, ensuring safety, comfort, and adequate access to the surgical site. When disposed of, however, these products are harmful to the environment as they are made from materials that consist largely of petroleum-based derivatives. These compounds and the other hazardous byproducts from their production are not only harmful to the environment, but also incur higher handling and disposal costs that are inevitably passed on to the Customer.

Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

Hubble Telemedical is dedicated to enabling earlier detection of systemic and debilitating diseases that manifest in the retina - the light-sensitive membrane at the back of the eye that transmits visual information to the brain - for more effective treatment and patient care. In addition to eye diseases such as retinopathy, macular degeneration and glaucoma, a range of systemic diseases such cardiovascular and immune diseases can be detected in the retina. Early diagnosis is essential for effective treatment of these diseases. Unfortunately, many at-risk individuals do not receive annual retinal exams due to inconvenience or unavailability. The result is that many individuals go undiagnosed until severe damage has occurred, causing medical complications and increased healthcare costs. They are changing that paradigm. Thanks to their proprietary, award-winning Telemedical Retinal Image Analysis and Diagnosis (TRIAD™) technology, Hubble Telemedical enables screening and diagnosis where and when it is most convenient for the healthcare consumer. They partner with healthcare providers, insurance companies, and employers to bring the power of retinal screening to the consumer. Their services are fully HIPAA-compliant, secure, and easy to use –- and multi-site, peer-reviewed and published clinical studies have demonstrated their ability to dramatically increase annual screening compliance, thereby decreasing overall healthcare costs and, most importantly, improving patients' health. They invite you to contact us to learn more about their services and technology— and how they can work with you to bring the power of retinal image analysis to your organization.

Cuff-Mate skin barriers offer healthcare professionals a cost-effective way to protect their patients, themselves and equipment when taking vital signs.

Hapten Sciences, Inc. is a privately-held biopharmaceutical company based in Memphis, Tennessee, established in 2010. The company focuses on the identification and development of early-stage products aimed at improving global health outcomes. One of its key innovations is PDC-APB, a vaccine designed to prevent contact dermatitis resulting from exposure to urushiol oil found in poison ivy, poison oak, and poison sumac. This product aims to provide patients with a solution to avoid allergic reactions without side effects, thereby contributing significantly to the well-being of individuals affected by these plants.

SurgiLight offers a surgical lighting system that provides surgeons with a practical illumination device, enabling them to focus on target areas.

We strive to eliminate the barriers of effective health care by addressing the major concerns that strain our system: time, and money. Our revolutionary technology is the first of its kind making it possible to test people for infections quickly and affordably. Most importantly we offer accurate test results without a doctor visit! Our solution stands alone as one that serves patients, empowers providers, and benefits payers.

Mobilizer Inc. is a company that specializes in the development of innovative six-wheeled holsters designed for medical equipment, aimed at enhancing the efficiency of patient ambulation in healthcare settings. Modeled after a wheeled walker, these holsters feature shelves and attachments that facilitate the transportation of equipment necessary for the mobility of critical care patients. By improving the process of medical ambulation, Mobilizer aims to enhance patient well-being while streamlining operations within hospitals. The company is a graduate of the ZeroTo510 medical device startup accelerator, further validating its commitment to advancing healthcare solutions.

Although it is still relatively new, AIS, having a relationship with other biology-inspired computing models, and computational biology.

Spinal Restoration, Inc. is a company focused on developing early intervention and minimally invasive therapies for chronic low back pain. Established in 2004 and headquartered in New York, it has created the Biostat System, which is designed to address chronic discogenic pain caused by internal disc disruptions. This system includes a resorbable biologic compound known as BIOSTAT BIOLOGX Fibrin Sealant, which acts as a tissue sealant, and a proprietary delivery device that administers the biologic directly to the intervertebral disc. The Biostat System aims to provide an effective treatment option for the significant population of adults—approximately four million—suffering from chronic low back pain.

Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.

AxioMed LLC specializes in designing and developing disc replacement devices aimed at alleviating neck pain and restoring normal spinal functions for patients suffering from degenerative disc disease. Founded in 2001 and based in Malden, Massachusetts, the company was previously known as AxioMed Spine Corporation until its name change in 2014. AxioMed has developed the Freedom® Lumbar Disc and initiated clinical trials for its products, which are intended to improve the standard of care beyond traditional fusion and first-generation artificial discs. The company is led by CEO Patrick McBrayer and COO James Kuras, who oversee a team with extensive experience in spinal implants and engineering. They are supported by a Medical Advisory Panel of surgeons from prominent spine centers and universities. AxioMed's operations encompass product development, testing, clinical and regulatory affairs, and manufacturing, with ongoing projects focusing on cervical spine solutions.

Restore Medical Solutions is a medical device company focusing on products and techniques that promote SSI reduction, safety, and productivity within healthcare. The company manufactures a sterilization tray system that reduces the risk of infection from contaminated medical instruments. Its modular sterilization tray systems reduce the potential risk of infection from contaminated instruments and enable surgical departments to improve the quality of care while reducing cost. Founded in 2012, Restore Medical Solutions is headquartered in Memphis, Tennessee.

Hubble Telemedical is dedicated to enabling earlier detection of systemic and debilitating diseases that manifest in the retina - the light-sensitive membrane at the back of the eye that transmits visual information to the brain - for more effective treatment and patient care. In addition to eye diseases such as retinopathy, macular degeneration and glaucoma, a range of systemic diseases such cardiovascular and immune diseases can be detected in the retina. Early diagnosis is essential for effective treatment of these diseases. Unfortunately, many at-risk individuals do not receive annual retinal exams due to inconvenience or unavailability. The result is that many individuals go undiagnosed until severe damage has occurred, causing medical complications and increased healthcare costs. They are changing that paradigm. Thanks to their proprietary, award-winning Telemedical Retinal Image Analysis and Diagnosis (TRIAD™) technology, Hubble Telemedical enables screening and diagnosis where and when it is most convenient for the healthcare consumer. They partner with healthcare providers, insurance companies, and employers to bring the power of retinal screening to the consumer. Their services are fully HIPAA-compliant, secure, and easy to use –- and multi-site, peer-reviewed and published clinical studies have demonstrated their ability to dramatically increase annual screening compliance, thereby decreasing overall healthcare costs and, most importantly, improving patients' health. They invite you to contact us to learn more about their services and technology— and how they can work with you to bring the power of retinal image analysis to your organization.

Spinal Restoration, Inc. is a company focused on developing early intervention and minimally invasive therapies for chronic low back pain. Established in 2004 and headquartered in New York, it has created the Biostat System, which is designed to address chronic discogenic pain caused by internal disc disruptions. This system includes a resorbable biologic compound known as BIOSTAT BIOLOGX Fibrin Sealant, which acts as a tissue sealant, and a proprietary delivery device that administers the biologic directly to the intervertebral disc. The Biostat System aims to provide an effective treatment option for the significant population of adults—approximately four million—suffering from chronic low back pain.

Nanophthalmics is a developer of innovative surgical devices and techniques aimed at enhancing treatment outcomes for ophthalmic and microsurgical diseases. The company has created a patent-pending platform technology for microfabricated instruments that engage tissue in novel ways. Their flagship product is a disposable corneal micro-punch, which is designed to improve healing in cases of abrasions, recurrent erosions, and other corneal diseases by altering tissue attachments at the cellular level. By focusing on advanced surgical devices and methods, Nanophthalmics seeks to transform the landscape of ophthalmic treatment and offer better solutions for healthcare providers.

EcoSurg™ (pronounced eek-oh-surj) is a developer of environmentally-friendly surgical supplies that is dedicated to reducing the carbon footprint of the surgical suite. Their flagship product is the EcoSurg™ line of Patient Positioners. Disposable patient positioners are used in over 20 Million surgical procedures per year in the United States alone. These foam shapes are used to properly position patients in a variety of positions, ensuring safety, comfort, and adequate access to the surgical site. When disposed of, however, these products are harmful to the environment as they are made from materials that consist largely of petroleum-based derivatives. These compounds and the other hazardous byproducts from their production are not only harmful to the environment, but also incur higher handling and disposal costs that are inevitably passed on to the Customer.

Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.

Urova Medical Inc. is a urological device company based in Memphis, Tennessee, focused on creating innovative solutions for stress urinary incontinence in women. Founded in 2012, the company developed its technology through a collaborative effort by biomedical engineering students at Johns Hopkins University, guided by expert physicians from the institution's renowned urological center. Urova Medical collaborates with urologists, gynecologists, and clinical researchers to create effective and convenient treatments for this condition. The company has also participated in the Zeroto510 Accelerator program, which is supported by local venture capital firms, further enhancing its development and outreach efforts.

BioNanovations is a medical technology company focused on the rapid diagnosis of bacterial infections, particularly Staphylococcus infections. Currently, diagnosing these infections takes 3 to 5 days, which can be critical due to the aggressive nature of certain strains that may lead to severe health consequences, including limb amputation or death within 48 hours. To address these challenges, BioNanovations is developing a handheld diagnostic platform that significantly reduces the testing time to under 30 minutes. This integrated real-time diagnostic solution enables healthcare professionals to quickly analyze blood, sputum, urine, and cerebrospinal fluid, facilitating immediate access to vital diagnostic information. By providing real-time data on bacterial infections, the platform not only improves patient outcomes by reducing morbidity and mortality rates but also supports healthcare professionals and agencies in tracking epidemiological trends effectively.

EcoSurg™ (pronounced eek-oh-surj) is a developer of environmentally-friendly surgical supplies that is dedicated to reducing the carbon footprint of the surgical suite. Their flagship product is the EcoSurg™ line of Patient Positioners. Disposable patient positioners are used in over 20 Million surgical procedures per year in the United States alone. These foam shapes are used to properly position patients in a variety of positions, ensuring safety, comfort, and adequate access to the surgical site. When disposed of, however, these products are harmful to the environment as they are made from materials that consist largely of petroleum-based derivatives. These compounds and the other hazardous byproducts from their production are not only harmful to the environment, but also incur higher handling and disposal costs that are inevitably passed on to the Customer.

Hubble Telemedical is dedicated to enabling earlier detection of systemic and debilitating diseases that manifest in the retina - the light-sensitive membrane at the back of the eye that transmits visual information to the brain - for more effective treatment and patient care. In addition to eye diseases such as retinopathy, macular degeneration and glaucoma, a range of systemic diseases such cardiovascular and immune diseases can be detected in the retina. Early diagnosis is essential for effective treatment of these diseases. Unfortunately, many at-risk individuals do not receive annual retinal exams due to inconvenience or unavailability. The result is that many individuals go undiagnosed until severe damage has occurred, causing medical complications and increased healthcare costs. They are changing that paradigm. Thanks to their proprietary, award-winning Telemedical Retinal Image Analysis and Diagnosis (TRIAD™) technology, Hubble Telemedical enables screening and diagnosis where and when it is most convenient for the healthcare consumer. They partner with healthcare providers, insurance companies, and employers to bring the power of retinal screening to the consumer. Their services are fully HIPAA-compliant, secure, and easy to use –- and multi-site, peer-reviewed and published clinical studies have demonstrated their ability to dramatically increase annual screening compliance, thereby decreasing overall healthcare costs and, most importantly, improving patients' health. They invite you to contact us to learn more about their services and technology— and how they can work with you to bring the power of retinal image analysis to your organization.

Hapten Sciences, Inc. is a privately-held biopharmaceutical company based in Memphis, Tennessee, established in 2010. The company focuses on the identification and development of early-stage products aimed at improving global health outcomes. One of its key innovations is PDC-APB, a vaccine designed to prevent contact dermatitis resulting from exposure to urushiol oil found in poison ivy, poison oak, and poison sumac. This product aims to provide patients with a solution to avoid allergic reactions without side effects, thereby contributing significantly to the well-being of individuals affected by these plants.

Urova Medical Inc. is a urological device company based in Memphis, Tennessee, focused on creating innovative solutions for stress urinary incontinence in women. Founded in 2012, the company developed its technology through a collaborative effort by biomedical engineering students at Johns Hopkins University, guided by expert physicians from the institution's renowned urological center. Urova Medical collaborates with urologists, gynecologists, and clinical researchers to create effective and convenient treatments for this condition. The company has also participated in the Zeroto510 Accelerator program, which is supported by local venture capital firms, further enhancing its development and outreach efforts.

S2 Interactive, Inc. is a Delaware C corp. founded by Larry Foster, R.N., in September, 2011. After working as a surgical nurse and spending 26 years in leadership roles within sales, marketing and professional education in the orthopedic & spine industry, Larry was convinced there was an opportunity to teach hospital staff to learn and manage surgical instruments more efficiently and safely. Larry spent five years working with technology experts realizing with the current trends in healthcare there was a clear need to increase hospital staff productivity/efficiency while driving cost savings. Larry’s vision combined with the introduction of user-friendly “hand held” technology platforms (tablets) enabled S2 Interactive to develop Virtual Back Table and Tray Touch software platforms. In September, 2011 additional funding was provided by 2 Memphis based venture capital organizations, Innova & MB Ventures. They are proud to be working with market leading companies in Medical Devices and many of the nation’s most prominent hospitals. Their technology has been used by over 1,000 different users in a variety of surgical specialties including cardiology, orthopedics, spine , general surgery and trauma.

Currently, there are 7M stroke survivors in the US. Additionally, there are more than 795K new or recurrent stroke survivors every year. Americans pay $73.7B annually for stroke-related medical costs and disability. Approximately 60% of them suffer from hand dysfunction. Current treatments and devices for hand dysfunction focus primarily on muscle rehabilitation, with the patient taking a passive role. Further, these interventions are expensive and inconvenient. Current treatments are inadequate, as recent studies show that active engagement of the brain during hand rehabilitation improves the amount of hand movement by 2x over traditional treatments and further improves the quality of hand movement by 2.5x over these traditional methods. Based on this research, we created the HandMinder portable hand rehabilitation device which employs patent-pending vibration-guided brain engagement technology that strengthens the neural connections between the hand and brain, producing marked improvement in patients’ hand function. Further, HandMinder is affordable, convenient, and used in clinical settings and at home.

Zyga Technology, Inc. is a medical device company focused on developing and commercializing minimally invasive products for underserved conditions of the lumbar spine. The company offers the SImmetry Sacroiliac Joint Fusion System, which provides a surgical solution for sacroiliac joint fusion, addressing issues such as joint disruptions and degenerative sacroiliitis. Additionally, Zyga is working on the Glyder Facet Restoration System, an investigational device aimed at treating chronic facetogenic pain. Founded in 2008 and based in Minnetonka, Minnesota, Zyga Technology has assembled a skilled team with extensive experience in the spine industry. As of late 2017, Zyga operates as a subsidiary of RTI Surgical, Inc.

Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.

Cayenne Medical, Inc. a sports medicine company, provides arthroscopic surgery products. It offers AperFix System that enables the surgeons to perform anterior cruciate ligament (ACL) reconstruction using the hamstring and various soft tissue grafts. The company also provides AperFix Femoral device to restore native knee kinematics; AperFix Tibial device for anatomic reconstruction applications; and iFix Interference Screw System for ACL reconstruction procedure using the bone-patellar tendon-bone and various bone-tendon-bone grafts. In addition, it offers interference screws and shoulder products. Cayenne Medical, Inc. was founded in 2005 and is based in Scottsdale, Arizona.

MB Innovations, Inc. is a medical technology development company based in Memphis, Tennessee, founded in 2011. The company specializes in providing research, design, and development services for established firms, particularly in the musculoskeletal industry, on a fee-for-service basis. Its offerings encompass the entire development process, from initial concept to first-in-man surgical procedures, allowing clients to enhance their products and secure market presence. Additionally, MB Innovations aims to develop its own technologies and intellectual property, fostering new ventures and job creation in the region. The company's strategic location in Memphis offers access to significant research and development capabilities, supported by a team of experienced engineers and surgeon advisors, which facilitates a focused approach to product development and accelerates time to market.

Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

AxioMed LLC specializes in designing and developing disc replacement devices aimed at alleviating neck pain and restoring normal spinal functions for patients suffering from degenerative disc disease. Founded in 2001 and based in Malden, Massachusetts, the company was previously known as AxioMed Spine Corporation until its name change in 2014. AxioMed has developed the Freedom® Lumbar Disc and initiated clinical trials for its products, which are intended to improve the standard of care beyond traditional fusion and first-generation artificial discs. The company is led by CEO Patrick McBrayer and COO James Kuras, who oversee a team with extensive experience in spinal implants and engineering. They are supported by a Medical Advisory Panel of surgeons from prominent spine centers and universities. AxioMed's operations encompass product development, testing, clinical and regulatory affairs, and manufacturing, with ongoing projects focusing on cervical spine solutions.

Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).

Calosyn Pharma focuses on developing innovative treatments for osteoarthritis. Its product, CAL-05CR, is a sustained-release injectable therapy that combines verapamil with a biodegradable delivery system. This treatment is designed to provide long-lasting pain relief and reduce inflammation by targeting the underlying causes of osteoarthritis, such as abnormal calcium ion channel signaling.

Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).

Visioneering Technologies, Inc., based in Alpharetta, Georgia, is a medical device company focused on advancing vision care through innovative products. The company specializes in the design, manufacture, and distribution of NaturalVue daily disposable multifocal contact lenses, which cater to adults with presbyopia and children with myopia. These lenses are designed to provide clear vision at near, intermediate, and distance ranges, significantly improving patient outcomes and easing the fitting process for eye care professionals. Founded by Dr. Richard A. Griffin, who possesses extensive experience in optometry and optical engineering, Visioneering holds fourteen patents worldwide aimed at addressing the challenges of presbyopia and myopia. The company combines expertise from various sectors, including clinical, marketing, engineering, manufacturing, and regulatory, leveraging the knowledge of seasoned professionals to create effective solutions for vision care.

BrainsGate, Ltd. is a medical device company based in Caesarea, Israel, specializing in therapies for patients with central nervous system diseases. The company has developed a technology platform that utilizes electrical stimulation of the spheno-palatine ganglion (SPG) to enhance cerebral blood flow. Currently, BrainsGate is focused on treating acute ischemic stroke through its innovative ischemic stroke system, which involves a miniature electrode implanted in the roof of the mouth during a minimally invasive procedure. This method is performed under local anesthesia and is comparable to standard dental treatments. The company has conducted several clinical trials, including a pivotal trial with 300 patients that validated the safety and efficacy of its treatment. BrainsGate is also engaged in a multi-national, randomized study known as ImpACT-24b, aimed at further assessing the effectiveness of its approach within a critical 24-hour window following a stroke.

Protein Discovery, Inc., a life sciences company, develops and commercializes sample preparation technologies that enable protein and peptide analysis using mass spectrometry. It provides Gelfree 8100, a fractionation system that partitions complex protein mixtures into liquid-phase molecular weight fractions; Passport 1200, a sample preparation system that enriches low molecular weight proteins and peptides, and removes matrix interferences for high-throughput quantification applications; and PPS Silent Surfactant, a protein preparation reagent that solubilizes membrane proteins and cleaves to eliminate detergent interference. The company also provides UPX universal protein extraction kit for detergent extraction of proteins from cells and tissues. It serves life science researchers and drug development scientists. The company markets its products through Agilent Technologies, as well as online in the United States and internationally. Protein Discovery, Inc. was founded as Qgenics Biosciences, Inc. in 2001 and changed its name to Protein Discovery, Inc. in April 2004. The company is based in Knoxville, Tennessee.

Cayenne Medical, Inc. a sports medicine company, provides arthroscopic surgery products. It offers AperFix System that enables the surgeons to perform anterior cruciate ligament (ACL) reconstruction using the hamstring and various soft tissue grafts. The company also provides AperFix Femoral device to restore native knee kinematics; AperFix Tibial device for anatomic reconstruction applications; and iFix Interference Screw System for ACL reconstruction procedure using the bone-patellar tendon-bone and various bone-tendon-bone grafts. In addition, it offers interference screws and shoulder products. Cayenne Medical, Inc. was founded in 2005 and is based in Scottsdale, Arizona.

Spinal Restoration, Inc. is a company focused on developing early intervention and minimally invasive therapies for chronic low back pain. Established in 2004 and headquartered in New York, it has created the Biostat System, which is designed to address chronic discogenic pain caused by internal disc disruptions. This system includes a resorbable biologic compound known as BIOSTAT BIOLOGX Fibrin Sealant, which acts as a tissue sealant, and a proprietary delivery device that administers the biologic directly to the intervertebral disc. The Biostat System aims to provide an effective treatment option for the significant population of adults—approximately four million—suffering from chronic low back pain.

Applied Spine Technologies designs and develops specialty medical devices. The company offers spine stabilization systems that support patients with an injured or degenerated spine without eliminating motion. It is headquartered in Wellesley, Massachusetts.

Cayenne Medical, Inc. a sports medicine company, provides arthroscopic surgery products. It offers AperFix System that enables the surgeons to perform anterior cruciate ligament (ACL) reconstruction using the hamstring and various soft tissue grafts. The company also provides AperFix Femoral device to restore native knee kinematics; AperFix Tibial device for anatomic reconstruction applications; and iFix Interference Screw System for ACL reconstruction procedure using the bone-patellar tendon-bone and various bone-tendon-bone grafts. In addition, it offers interference screws and shoulder products. Cayenne Medical, Inc. was founded in 2005 and is based in Scottsdale, Arizona.

Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).

KFx Medical specializes in developing and manufacturing innovative soft tissue fixation implants tailored for orthopedic sports medicine. The company offers a range of products designed for tissue fixation, which can be directly placed into bones with or without sutures. These implants are applicable in various orthopedic surgical procedures, allowing surgeons to effectively reattach tissue in regions such as the shoulder, knee, foot, and ankle. KFx Medical collaborates closely with leading orthopedic surgeons to create advanced technologies and reliable surgical implants, ultimately aiming to improve surgical outcomes for patients.

BrainsGate, Ltd. is a medical device company based in Caesarea, Israel, specializing in therapies for patients with central nervous system diseases. The company has developed a technology platform that utilizes electrical stimulation of the spheno-palatine ganglion (SPG) to enhance cerebral blood flow. Currently, BrainsGate is focused on treating acute ischemic stroke through its innovative ischemic stroke system, which involves a miniature electrode implanted in the roof of the mouth during a minimally invasive procedure. This method is performed under local anesthesia and is comparable to standard dental treatments. The company has conducted several clinical trials, including a pivotal trial with 300 patients that validated the safety and efficacy of its treatment. BrainsGate is also engaged in a multi-national, randomized study known as ImpACT-24b, aimed at further assessing the effectiveness of its approach within a critical 24-hour window following a stroke.

AxioMed LLC specializes in designing and developing disc replacement devices aimed at alleviating neck pain and restoring normal spinal functions for patients suffering from degenerative disc disease. Founded in 2001 and based in Malden, Massachusetts, the company was previously known as AxioMed Spine Corporation until its name change in 2014. AxioMed has developed the Freedom® Lumbar Disc and initiated clinical trials for its products, which are intended to improve the standard of care beyond traditional fusion and first-generation artificial discs. The company is led by CEO Patrick McBrayer and COO James Kuras, who oversee a team with extensive experience in spinal implants and engineering. They are supported by a Medical Advisory Panel of surgeons from prominent spine centers and universities. AxioMed's operations encompass product development, testing, clinical and regulatory affairs, and manufacturing, with ongoing projects focusing on cervical spine solutions.

BioMimetic Therapeutics is a biotechnology company that develops products to help stimulate the body natural tissue regenerative process. The company's products and product candidates include Augment Injectable and Augment Rotator Cuff for several orthopedic and sports medicine indications comprising the treatment of foot and ankle fusions, the stimulation of wrist fracture healing, and the surgical treatment of rotator cuff tears, as well as Augment Tendinopathy Injection for injuries cause of tendon overuse. BioMimetic Therapeutics was founded on 1999 and is headquartered in Franklin, Tennessee.

Alveolus is a leader in the emerging field of non-vascular interventional stenting through next generation stent technology.

Established in 1999, Salient Surgical Technologies, Inc. is a global, privately held medical technology company that develops and markets advanced energy devices used in surgical procedures. Salient’s first line of products were monopolar electrosurgical devices used for the treatment of liver cancers. Today, the company’s bipolar AQUAMANTYS® System is used across a wide range of surgical procedures including orthopaedic reconstruction, spine surgery, orthopaedic trauma, and surgical oncology. Comprised of a bipolar electrosurgical generator & pump system and a portfolio of handheld disposable device, the AQUAMANTYS system uses patented TRANSCOLLATION® technology to haemostatically seal soft tissue and bone, enabling surgeons to reduce and prevent surgical blood loss. Salient’s products are sold throughout the United States, Europe, and Asia, providing clinical and economic benefits to hospitals, healthcare providers, and patients all over the world. To date, more than 500,000 patients have been treated with TRANSCOLLATION technology.

GTx, Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of innovative treatments for stress urinary incontinence and prostate cancer. The company specializes in selective androgen receptor modulators (SARMs) and selective androgen receptor degraders, targeting conditions such as breast cancer and Duchenne muscular dystrophy. One of its notable product candidates is enobosarm GTx-024, which is undergoing Phase II clinical trials for patients with specific types of breast cancer and postmenopausal women suffering from stress urinary incontinence. Founded in 1997 and based in Memphis, Tennessee, GTx aims to advance medical solutions by leveraging new scientific approaches. In 2019, GTx was acquired by Oncternal Therapeutics in a reverse merger.

BioMimetic Therapeutics is a biotechnology company that develops products to help stimulate the body natural tissue regenerative process. The company's products and product candidates include Augment Injectable and Augment Rotator Cuff for several orthopedic and sports medicine indications comprising the treatment of foot and ankle fusions, the stimulation of wrist fracture healing, and the surgical treatment of rotator cuff tears, as well as Augment Tendinopathy Injection for injuries cause of tendon overuse. BioMimetic Therapeutics was founded on 1999 and is headquartered in Franklin, Tennessee.

TriVirix International is a U.S.-based manufacturer and designer of electro-mechanical medical devices, diagnostic tools, and life-science equipment. Headquartered in Milaca, Minnesota, the company specializes in producing a range of products, including ribo printers, point-of-care blood testing analyzers, volumetric infusion pumps, and vital sign monitors. TriVirix International focuses on delivering innovative solutions for the healthcare industry, addressing the needs of medical professionals and enhancing patient care through advanced technology.