Kyoto University Innovation Capital

Kyoto University Innovation Capital Co., Ltd. (Kyoto iCAP) is a venture capital firm established in December 2014, wholly funded by Kyoto University. Located in Kyoto, Japan, the firm focuses on providing investment and support to startups emerging from Kyoto University, with an emphasis on commercializing research outcomes and technologies developed by its researchers. Kyoto iCAP specializes in various sectors, including healthcare, medical devices, biotechnology, drug discovery, internet of things, artificial intelligence, machinery, clean technology, energy, new materials, food, and agriculture. The firm aims to bridge the gap between academic research and marketable innovations, fostering the growth of spin-off companies that leverage the university's intellectual assets.

Ko Kusumi

President and CEO

Tsuyoshi Tsujimura

Investment Manager

82 past transactions

RegCell

Seed Round in 2025
RegCell is a biotechnology company focused on developing innovative therapeutic technologies to address autoimmune diseases and cancer. The company specializes in creating advanced cell therapies that work by controlling and augmenting the immune system. RegCell's approach involves returning regulatory T cells and activating them in vitro, allowing for effective treatment options for patients facing these challenging health conditions. By targeting unmet medical needs, RegCell aims to improve patient outcomes and provide new hope for those suffering from autoimmune disorders and cancer.

JiMED

Series A in 2025
JiMED is a company focused on developing wireless embedded brain-computer interface (BCI) systems that facilitate the reading of brain activity. It offers a wireless implantable BCI system that utilizes an implanted device combined with artificial intelligence to interpret neural signals. This innovative technology enables individuals, particularly those suffering from ALS, to communicate more effectively and improve their quality of life by allowing them to operate the device through thought alone.

Holo Bio

Seed Round in 2025
Holo Bio is a research and technology firm that specializes in biological breeding techniques to tackle global food challenges. The company has developed a novel organism breeding technology centered around the intestinal bacterium GI35, which was identified in the fish species endemic to Lake Biwa, Isaza. This innovative approach allows Holo Bio to enhance the productivity of polyunsaturated fatty acids (PUFAs) and supply eicosapentaenoic acid (EPA) derived from fish. By transforming previously inedible plant fibers into consumable products, Holo Bio aims to contribute to sustainable food solutions and improve the availability of nutritious resources for society.

Enu Pharma

Seed Round in 2024
Enu Pharma is a pharmaceutical company focused on innovative research and the development of advanced medicines aimed at improving global healthcare standards. The company specializes in nanosome technology, which is designed to assist medical professionals in treating intractable diseases. This technology features core metals enveloped in an antiadhesive mixed self-assembled monolayer, which helps prevent the non-specific surface protein corona that can hinder drug efficacy. By leveraging this unique approach, Enu Pharma aims to enhance drug discovery, development, and delivery, ultimately contributing to more effective treatment options for challenging medical conditions.

Koala Tech

Series B in 2024
Koala Tech Inc. is a high-tech startup based in Fukuoka, Japan, founded in 2019. The company specializes in the development of organic semiconductor laser diodes, a pioneering technology that emerged from research at the Center for Organic Photonics and Electronics Research at Kyushu University. Koala Tech's innovative approach utilizes organic fluorescent semiconductors, which are easier and less harmful to process into thin films. This technology offers a low-cost light source that can be seamlessly integrated into OLED and organic electronic platforms, aiming to create practical applications for these advanced laser diodes.

Rhinoflux

Seed Round in 2024
Rhinoflux is an energy management company specializing in advanced thermal management technologies for efficient cooling systems.

OOYOO

Seed Round in 2024
OOYOO is a technology company specializing in the research and development of advanced gas separation membranes. Their primary focus is on carbon dioxide and hydrogen separation, aiming to create cleaner and more efficient air and gas purification solutions. The company's innovative, compact, and portable systems are designed to help industries reduce operational costs and promote sustainability, catering to sectors involved in environmental preservation and clean energy initiatives.

Rege Nephro

Series B in 2024
Rege Nephro Co., Ltd. is a biotechnology company based in Kyoto, Japan, founded in 2019. It specializes in the research and development, production, and marketing of therapeutics for renal diseases, utilizing nephron progenitor cells and induced pluripotent stem cell (iPSC) technology from the Center for iPS Cell Research and Application at Kyoto University. The company focuses on developing innovative treatments and cell therapies for kidney, liver, and pancreas diseases, aiming to reduce the reliance on dialysis for patients with renal failure. Additionally, Rege Nephro produces kidney organoids that facilitate nephrotoxicity screening for drug discovery, enhancing applied research in the field of nephrology.

RadioNano Therapeutics

Series A in 2024
RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.

Symbiobe

Series A in 2024
Symbiobe is engaged in the development of a resource-recycling material production platform that aims to promote sustainability through the effective utilization of underutilized natural biomass resources and photosynthetic organisms. The company focuses on creating alternatives for greenhouse gas fixation and producing industrial biopolymers, nitrogen fertilizers, and aquaculture feed. By advancing manufacturing processes that prioritize environmental sustainability, Symbiobe supports the transition to a more sustainable society and provides essential resources for environmental start-up businesses seeking natural and sustainable products.

EneCoat

Series C in 2024
EneCoat Technologies, established in 2018 and headquartered in Kyoto, Japan, specializes in the manufacturing and sale of perovskite solar cells and associated materials. The company focuses on developing and commercializing thin-film solar cell technologies, aiming to generate power even in low-light conditions. EneCoat's mission is to protect the environment and efficiently harness natural energy sources, enabling businesses to conveniently produce energy from solar cells.

Grand Green

Series C in 2024
Grand Green, established in 2017 and headquartered in Nagoya, Japan, specializes in the production of new seeds and seedlings through automatic grafting techniques. As a research and development agribio venture, the company focuses on innovative approaches to enhance agricultural practices and improve crop yield. By leveraging advanced technology in seedling production, Grand Green aims to contribute to the agricultural sector's growth and sustainability.

RadioNano Therapeutics

Seed Round in 2024
RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.

Restore Vision

Series A in 2023
Restore Vision is a biotechnology company focused on developing innovative therapies for eye diseases, particularly retinitis pigmentosa. The company specializes in gene therapy that employs advanced chimeric rhodopsin genes, which enhance the functionality of conventional rhodopsins. This technology aims to address the limitations of traditional treatments, providing high sensitivity and improved outcomes for patients suffering from intractable eye conditions. Through its research and development efforts, Restore Vision seeks to create effective therapeutic agents that significantly contribute to the field of ocular health.

Melody International

Venture Round in 2023
Melody International is a manufacturing company that specializes in developing medical equipment for remote medical services. The company has created a fetal monitoring device designed to assist healthcare providers during challenging delivery situations. This device includes a fetal heart monitor, a uterine contraction monitor, and a tablet interface, which features a built-in speaker in the transducer connected via the internet. The system also functions as a fetal doppler, allowing women to monitor both maternal and fetal health conditions from distant locations. Through its innovative technology, Melody International aims to enhance access to essential medical care in remote areas.

QSimulate

Venture Round in 2023
QSimulate is a Boston-based company that specializes in developing cloud-based quantitative simulation tools focused on quantum molecular simulations. By leveraging the principles of quantum mechanics, QSimulate aims to address significant industrial-scale challenges primarily within the chemical and pharmaceutical sectors. Its innovative platform automates various workflows, allowing computational scientists to shift their focus from repetitive tasks to more strategic activities, ultimately enhancing productivity. This approach enables clients to accelerate their research and development processes, positioning QSimulate as a key player in advancing scientific inquiry and innovation in these industries.

Sunlit Seedlings

Seed Round in 2022
Sunlit Seedlings is a consulting firm specializing in the diagnosis of biological communities and ecosystems. The company integrates various scientific disciplines, including mycology, ecology, and network science, to provide comprehensive solutions. Its services focus on enhancing sustainable food supply systems and stabilizing the global environment. By emphasizing the importance of soil ecosystems in agricultural practices, Sunlit Seedlings aims to educate communities and societies on ecological value and sustainability.

Symbiobe

Seed Round in 2022
Symbiobe is engaged in the development of a resource-recycling material production platform that aims to promote sustainability through the effective utilization of underutilized natural biomass resources and photosynthetic organisms. The company focuses on creating alternatives for greenhouse gas fixation and producing industrial biopolymers, nitrogen fertilizers, and aquaculture feed. By advancing manufacturing processes that prioritize environmental sustainability, Symbiobe supports the transition to a more sustainable society and provides essential resources for environmental start-up businesses seeking natural and sustainable products.

Toregem Biopharma

Venture Round in 2022
Toregem Biopharma is a startup based in Kyoto, Japan, affiliated with Kyoto University, focused on developing innovative treatments for congenital adentia and other dental health issues. The company specializes in therapeutic agents aimed at dental regeneration, specifically designed to restore teeth using patients' own tissues. By researching and advancing dental regenerative medicine, Toregem Biopharma seeks to provide solutions for individuals who have lost their teeth due to conditions such as tooth decay or periodontal disease, ultimately helping them regain a healthy and functional smile.

Viage Therapeutics

Seed Round in 2022
Viage Therapeutics is a neuroscience company established in 2018, focusing on the development of innovative neurotherapeutics. The company is dedicated to discovering and creating a new class of drugs aimed at treating psychiatric and inflammatory diseases, including conditions such as depression, anxiety, and gastrointestinal disorders. Through its groundbreaking research, Viage Therapeutics seeks to address significant unmet medical needs, providing healthcare professionals with access to novel therapeutic options that could improve patient outcomes.

Rege Nephro

Venture Round in 2022
Rege Nephro Co., Ltd. is a biotechnology company based in Kyoto, Japan, founded in 2019. It specializes in the research and development, production, and marketing of therapeutics for renal diseases, utilizing nephron progenitor cells and induced pluripotent stem cell (iPSC) technology from the Center for iPS Cell Research and Application at Kyoto University. The company focuses on developing innovative treatments and cell therapies for kidney, liver, and pancreas diseases, aiming to reduce the reliance on dialysis for patients with renal failure. Additionally, Rege Nephro produces kidney organoids that facilitate nephrotoxicity screening for drug discovery, enhancing applied research in the field of nephrology.

BTB Drug Development Research Center

Seed Round in 2021
BTB Drug Discovery Research Center aims to contribute to reducing illness and saving lives. They create the product concept (TPP) and develop the finest plans possible for R&D, intellectual property, and pharmaceutical affairs. The company is developing a therapeutic medicine using a unique mechanism of action that encourages the release of endogenous opioids.

Myoridge

Venture Round in 2021
Myoridge Co. Ltd., established in 2016 and headquartered in Kyoto, Japan, specializes in developing a suspension culture system for scalable differentiation of pluripotent cells into desired cell types, notably cardiomyocytes. The company's innovative process employs a proprietary small-molecule compound, eliminating the need for proteins, thereby reducing production costs and ensuring lot-to-lot uniformity. Myoridge offers iPS cell-derived cardiomyocytes, cardiomyocyte fibers, and software for myocardial motion/fluorescence analysis, enabling advancements in regenerative medicine and drug discovery research.

Melody International

Venture Round in 2021
Melody International is a manufacturing company that specializes in developing medical equipment for remote medical services. The company has created a fetal monitoring device designed to assist healthcare providers during challenging delivery situations. This device includes a fetal heart monitor, a uterine contraction monitor, and a tablet interface, which features a built-in speaker in the transducer connected via the internet. The system also functions as a fetal doppler, allowing women to monitor both maternal and fetal health conditions from distant locations. Through its innovative technology, Melody International aims to enhance access to essential medical care in remote areas.

Cuorips

Venture Round in 2020
Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, it focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. The company offers manufacturing and sales of cellular and tissue-based products, along with contract development and manufacturing services. Cuorips aims to advance medical treatments through innovation in cell processing and therapeutic applications.

Perseus Proteomics

Venture Round in 2020
Perseus Proteomics Inc. is a biotechnology company based in Tokyo, Japan, focused on drug discovery. Established in 2001, it specializes in antibody discovery, engineering, and research support activities. The company engages in target discovery and functional protein expression, offering services such as mouse hybridoma sequencing, recombinant protein production, and contract research for antibodies. Additionally, Perseus Proteomics develops, manufactures, and supplies a range of antibody products. By leveraging advanced antibody technology, the company aims to create innovative medicines that address the needs of patients worldwide seeking improved medical care.

Kyoto Fusioneering

Seed Round in 2020
Kyoto Fusioneering is a privately funded technology start-up established in 2019 and based in Kyoto, Japan. The company specializes in the development of advanced technologies for commercial fusion reactors, aiming to facilitate the practical realization of fusion energy. Its offerings include gyrotron systems, tritium fuel cycle technologies, and breeding blankets for tritium production and power generation. By providing innovative solutions such as liquid metal and molten salt systems, as well as tritium treatment and high-frequency microwave gyrotron technologies, Kyoto Fusioneering supports both public and private fusion developers globally. The company's efforts are directed toward making fusion a viable and sustainable energy source, contributing to the reduction of carbon dioxide emissions and addressing the global energy challenge.

ACT Genomics

Venture Round in 2020
ACT Genomics is a cancer molecular information service company that specializes in transforming cancer genomic information into precision diagnostics and personalized treatment strategies. With a team of experts experienced in oncology, cancer genomics, and bioinformatics, the company utilizes next-generation sequencing and multiplex molecular testing to provide comprehensive tumor profiling. This approach enables oncologists to identify specific genetic alterations that drive tumor development and influence treatment responses. By leveraging advanced bioinformatics tools and curated proprietary databases, ACT Genomics aims to enhance the effectiveness of cancer treatments and improve patient outcomes. The company’s services reflect a growing trend in oncology, where understanding the unique molecular characteristics of a patient's cancer is essential for developing tailored treatment plans.

Toregem Biopharma

Seed Round in 2020
Toregem Biopharma is a startup based in Kyoto, Japan, affiliated with Kyoto University, focused on developing innovative treatments for congenital adentia and other dental health issues. The company specializes in therapeutic agents aimed at dental regeneration, specifically designed to restore teeth using patients' own tissues. By researching and advancing dental regenerative medicine, Toregem Biopharma seeks to provide solutions for individuals who have lost their teeth due to conditions such as tooth decay or periodontal disease, ultimately helping them regain a healthy and functional smile.

FLOSFIA

Venture Round in 2020
FLOSFIA INC. is a Tokyo-based company that focuses on the development of corundum structured Gallium Oxide semiconductor power devices. Founded on March 31, 2011, the company emerged as a spin-off from research conducted at Kyoto University. FLOSFIA specializes in film-formation using mist chemical vapor deposition (CVD) techniques, leveraging the unique physical properties of gallium oxide (Ga2O3) to create high breakdown voltage and high efficiency power devices. The firm is dedicated to advancing low-loss power device technology, contributing to the evolution of semiconductor applications.

U-Map

Venture Round in 2020
U-MaP Co., Ltd. is a manufacturer based in Nagoya, Japan, specializing in aluminum nitride (AlN) whiskers designed for thermal management and heat dissipation applications. Established in 2016, the company originates from research initiatives at Nagoya University and focuses on commercializing advanced materials and processing technologies. U-MaP is committed to addressing global challenges in manufacturing by developing conductive materials with high thermal conductivity and insulating properties. This innovative approach aims to enhance product quality and sustainability across various industries, positioning U-MaP as a key player in the development of next-generation industrial materials.

Rege Nephro

Series A in 2020
Rege Nephro Co., Ltd. is a biotechnology company based in Kyoto, Japan, founded in 2019. It specializes in the research and development, production, and marketing of therapeutics for renal diseases, utilizing nephron progenitor cells and induced pluripotent stem cell (iPSC) technology from the Center for iPS Cell Research and Application at Kyoto University. The company focuses on developing innovative treatments and cell therapies for kidney, liver, and pancreas diseases, aiming to reduce the reliance on dialysis for patients with renal failure. Additionally, Rege Nephro produces kidney organoids that facilitate nephrotoxicity screening for drug discovery, enhancing applied research in the field of nephrology.

Fimecs

Series A in 2020
Fimecs is a biotechnology company that specializes in drug discovery focused on protein degradation technology. The firm aims to develop first-in-class therapeutics targeting the degradation of proteins associated with cancers and other challenging diseases. Utilizing a proprietary platform based on ubiquitin E3 ligase binders, Fimecs designs small molecules that can induce the degradation of specific proteins, many of which are considered undruggable. This innovative approach targets proteins linked to various diseases, expanding the potential for effective treatment options beyond the traditionally druggable targets identified in small molecule drug discovery. Through its emphasis on targeted protein degradation, Fimecs is positioned to contribute significantly to the advancement of anti-cancer therapies and the treatment of other hard-to-treat conditions.

EneCoat

Venture Round in 2020
EneCoat Technologies, established in 2018 and headquartered in Kyoto, Japan, specializes in the manufacturing and sale of perovskite solar cells and associated materials. The company focuses on developing and commercializing thin-film solar cell technologies, aiming to generate power even in low-light conditions. EneCoat's mission is to protect the environment and efficiently harness natural energy sources, enabling businesses to conveniently produce energy from solar cells.

Tiem Factory

Venture Round in 2020
Tiem Factory Inc. is a Tokyo-based company founded in 2012 that specializes in the research, development, manufacturing, and sales of aerogel insulation materials under the brand SUFA. The company focuses on creating ultra-light transparent insulation products that serve as effective thermal insulation solutions. Tiem Factory's innovative approach allows it to produce these materials without the use of supercritical drying processes, resulting in insulation composed primarily of air. This unique manufacturing technique enhances the properties and applications of their insulation products, setting Tiem Factory apart in the industry.

LegalForce

Series B in 2020
LegalForce, Inc. is a Tokyo-based company founded in 2017 that specializes in developing software for legal services. It operates an AI-powered contract management platform designed to assist legal professionals in contract review. By utilizing natural language processing and other advanced technologies, LegalForce's platform helps users analyze contracts based on their specific types, while identifying potentially omitted or risky clauses. This functionality aids legal professionals in preventing oversights and enhancing the quality and efficiency of their operations, ultimately strengthening their legal systems.

LegalOn Technologies

Series B in 2020
LegalOn Technologies is a prominent provider of AI-driven contract review solutions, serving over 5,000 companies and firms worldwide. Founded in 2017, the company’s platform integrates artificial intelligence with the legal expertise of experienced attorneys, allowing legal teams to review and negotiate contracts up to 85% faster and more accurately. LegalOn's AI identifies potential risks within contracts, generates precise redlines, and adapts to the specific standards and preferences of each organization. This comprehensive solution streamlines various contract-related operations, saving significant time and reducing legal risks. Additionally, LegalOn offers customizable playbooks and an AI assistant that can be accessed online or integrated within Microsoft Word, enhancing the efficiency of legal and business teams. Operating globally, LegalOn has established a strong presence in both the US and Japan.

Kyoto Fusioneering

Seed Round in 2020
Kyoto Fusioneering is a privately funded technology start-up established in 2019 and based in Kyoto, Japan. The company specializes in the development of advanced technologies for commercial fusion reactors, aiming to facilitate the practical realization of fusion energy. Its offerings include gyrotron systems, tritium fuel cycle technologies, and breeding blankets for tritium production and power generation. By providing innovative solutions such as liquid metal and molten salt systems, as well as tritium treatment and high-frequency microwave gyrotron technologies, Kyoto Fusioneering supports both public and private fusion developers globally. The company's efforts are directed toward making fusion a viable and sustainable energy source, contributing to the reduction of carbon dioxide emissions and addressing the global energy challenge.

Myoridge

Seed Round in 2020
Myoridge Co. Ltd., established in 2016 and headquartered in Kyoto, Japan, specializes in developing a suspension culture system for scalable differentiation of pluripotent cells into desired cell types, notably cardiomyocytes. The company's innovative process employs a proprietary small-molecule compound, eliminating the need for proteins, thereby reducing production costs and ensuring lot-to-lot uniformity. Myoridge offers iPS cell-derived cardiomyocytes, cardiomyocyte fibers, and software for myocardial motion/fluorescence analysis, enabling advancements in regenerative medicine and drug discovery research.

Luxonus

Series A in 2019
Luxonus is a medical device manufacturing company that specializes in developing innovative imaging technology using photoacoustic methods. The company's core product is a diagnostic device that utilizes optical ultrasonic technology to capture ultra-high-resolution three-dimensional images of blood vessels and lymphatic vessels. This imaging approach allows for safe and non-invasive detection and diagnosis of diseases, providing healthcare professionals with a comprehensive understanding of disease onset, healing processes, and health conditions before and after illness. By combining light and ultrasonic waves, Luxonus aims to enhance medical imaging capabilities and improve patient outcomes.

Thyas

Venture Round in 2019
Thyas Co. Ltd., established in 2015, specializes in developing personalized regenerative immunocell therapies to treat cancer and infections. The company's core business involves generating regenerative T cells from human induced pluripotent stem (iPS) cells, aiming to enhance patients' immune systems for combating various diseases.

Algal Bio

Venture Round in 2019
Algal Bio Co., Ltd., established in 2018, is a Japanese company specializing in the research, development, production, and sale of algae and its components. Headquartered in Kashiwa, Japan, the company focuses on extracting rare fatty acids and carotenoids from algae, operating within food processing, importing, exporting, and distributing algae-related ingredients. Algal Bio was founded upon two decades of research from the University of Tokyo, aiming to harness microalgae's potential as functional food ingredients.

aceRNA Technologies

Series A in 2019
AceRNA Technologies is a biotechnology startup focused on developing patient-centric genetic therapies using its proprietary RNA switch technology for drug discovery. The company specializes in regenerative medicine, aiming to control gene expression with novel microRNA functions. Its innovative approach enables the removal of undifferentiated cells and other unnecessary cells that pose cancer risks, thereby advancing personalized healthcare solutions.

Thyas

Venture Round in 2019
Thyas Co. Ltd., established in 2015, specializes in developing personalized regenerative immunocell therapies to treat cancer and infections. The company's core business involves generating regenerative T cells from human induced pluripotent stem (iPS) cells, aiming to enhance patients' immune systems for combating various diseases.

Space Power Technologies

Venture Round in 2019
Space Power Technologies is a Japanese company founded in 2019, specializing in the development and manufacturing of microwave-based wireless power transmission systems. As Japan's first start-up focused on spatial transmission wireless power transmission, the company aims to address societal power supply challenges by integrating advanced technologies with practical applications. Its innovative systems offer diverse usage scenarios, including factories, logistics sites, infrastructure monitoring, depopulated areas lacking power wiring, disaster recovery situations, and even outer space. By enabling wireless power transfer over distances using radio waves, Space Power Technologies seeks to contribute to the creation of a wireless society, enhancing efficiency and accessibility in power delivery.

Kyulux

Series B in 2019
Kyulux, Inc. is a Japanese company specializing in the research and development of organic electroluminescent materials for organic light-emitting diode (OLED) displays and lighting solutions. Founded in 2015 and based in Fukuoka, Kyulux is a leader in the advancement of thermally activated delayed fluorescence (TADF) technology, which enhances the efficiency of OLED emission. The company offers innovative products, including its proprietary Hyperfluorescence solution, which combines TADF and fluorescence emitters. This technology enables manufacturers in the display and lighting industries to produce cost-effective, durable, and efficient OLED solutions without relying on rare metals. With a significant intellectual property portfolio developed at Kyushu University and in collaboration with industrial partners, Kyulux is positioned at the forefront of the OLED technology market.

On The Slope

Venture Round in 2019
On the way to Sakano deliver vegetables grown without the use of pesticides and chemical fertilizers, aiming to spread agriculture with low environmental impact. We want to make agriculture sustainable and reach a sustainable society.

Sho Engineering

Seed Round in 2019
Sho Engineering is a company dedicated to planning, research, and product development in the field of wireless transmission equipment. It specializes in creating innovative technologies aimed at enhancing safety and security in society. The company's offerings include a data transmitter powered by electrical energy from a wireless power transmitter, which facilitates the transmission of data, wireless power, and data transfer. Additionally, Sho Engineering develops devices for long-distance identity cards that utilize microwave radio waves to retrieve information from remote locations. The company also provides an emergency and volcano observation monitoring assistance system, equipping clients with advanced technology to improve safety and situational awareness.

AlphaNavi Pharma

Series A in 2019
AlphaNavi Pharma Co., Ltd. is a biotechnology company based in Kyoto, Japan, founded in 2019. The company focuses on drug discovery, specifically developing novel therapeutics for pain management. It is engaged in research and development of voltage-gated sodium channel selective inhibitors, with its primary products being ANP-230 and ANP-231, which are aimed at treating peripheral neuropathic pain. AlphaNavi Pharma collaborates with academic institutions and investors to enhance its research and clinical development efforts, striving to create innovative analgesic drugs that alleviate pain for patients and improve their quality of life.

Chordia Therapeutics

Series B in 2019
Chordia Therapeutics Inc. is a clinical-stage biotechnology company based in Fujisawa, Japan, founded in 2017. The company specializes in the research and development of innovative oncology drugs, focusing on delivering first-in-class therapies for cancers that currently have high unmet medical needs. Chordia Therapeutics is committed to advancing new therapeutic options to patients as swiftly as possible, aiming to address significant gaps in cancer treatment.

Luxonus

Venture Round in 2019
Luxonus is a medical device manufacturing company that specializes in developing innovative imaging technology using photoacoustic methods. The company's core product is a diagnostic device that utilizes optical ultrasonic technology to capture ultra-high-resolution three-dimensional images of blood vessels and lymphatic vessels. This imaging approach allows for safe and non-invasive detection and diagnosis of diseases, providing healthcare professionals with a comprehensive understanding of disease onset, healing processes, and health conditions before and after illness. By combining light and ultrasonic waves, Luxonus aims to enhance medical imaging capabilities and improve patient outcomes.

SOUSEI Technology

Venture Round in 2019
SOUSEI Technology, Inc., established in 2018 and headquartered in Tokyo, specializes in developing innovative home design and management solutions. The company offers an IoT device called v-ex, enabling voice-activated communication with home electronics. Additionally, SOUSEI provides Knot, an online platform facilitating connections between housing companies and homeowners while streamlining customer and property information management, documents, and security compliance.

LegalOn Technologies

Series A in 2019
LegalOn Technologies is a prominent provider of AI-driven contract review solutions, serving over 5,000 companies and firms worldwide. Founded in 2017, the company’s platform integrates artificial intelligence with the legal expertise of experienced attorneys, allowing legal teams to review and negotiate contracts up to 85% faster and more accurately. LegalOn's AI identifies potential risks within contracts, generates precise redlines, and adapts to the specific standards and preferences of each organization. This comprehensive solution streamlines various contract-related operations, saving significant time and reducing legal risks. Additionally, LegalOn offers customizable playbooks and an AI assistant that can be accessed online or integrated within Microsoft Word, enhancing the efficiency of legal and business teams. Operating globally, LegalOn has established a strong presence in both the US and Japan.

EneCoat

Venture Round in 2019
EneCoat Technologies, established in 2018 and headquartered in Kyoto, Japan, specializes in the manufacturing and sale of perovskite solar cells and associated materials. The company focuses on developing and commercializing thin-film solar cell technologies, aiming to generate power even in low-light conditions. EneCoat's mission is to protect the environment and efficiently harness natural energy sources, enabling businesses to conveniently produce energy from solar cells.

LegalForce

Seed Round in 2018
LegalForce, Inc. is a Tokyo-based company founded in 2017 that specializes in developing software for legal services. It operates an AI-powered contract management platform designed to assist legal professionals in contract review. By utilizing natural language processing and other advanced technologies, LegalForce's platform helps users analyze contracts based on their specific types, while identifying potentially omitted or risky clauses. This functionality aids legal professionals in preventing oversights and enhancing the quality and efficiency of their operations, ultimately strengthening their legal systems.

Mitsucari

Series B in 2018
Mitsucari is an HR technology service company that specializes in enhancing organizational effectiveness by analyzing individual personalities and compatibility within corporate environments. It has developed a candidate verification platform that assesses job seekers' personalities through aptitude tests while concurrently evaluating existing employees to understand the corporate culture. This dual analysis helps to identify compatibility between candidates and organizations, facilitating better job matching. By focusing on personality traits and desired work conditions, Mitsucari aims to improve the hiring process for employers and assist job seekers in finding positions that align with their values and preferences, ultimately contributing to employee retention and satisfaction.

aceRNA Technologies

Seed Round in 2018
AceRNA Technologies is a biotechnology startup focused on developing patient-centric genetic therapies using its proprietary RNA switch technology for drug discovery. The company specializes in regenerative medicine, aiming to control gene expression with novel microRNA functions. Its innovative approach enables the removal of undifferentiated cells and other unnecessary cells that pose cancer risks, thereby advancing personalized healthcare solutions.

Connexx Systems

Venture Round in 2018
Connexx Systems Corporation is a Kyoto-based company that specializes in the development and manufacturing of power storage systems, including household and mobile storage solutions for emergencies. Established in 2011, the company integrates core battery technologies with power generation facilities, utilizing renewable energy sources such as solar and wind power to provide alternative energy solutions. Connexx Systems markets its products through distributors and constructors, as well as through catalogs, offering innovative options for electric power generation and storage. With additional offices in Tokyo and Fukuoka, Connexx Systems aims to enhance energy accessibility and sustainability.

Cuorips

Venture Round in 2018
Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, it focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. The company offers manufacturing and sales of cellular and tissue-based products, along with contract development and manufacturing services. Cuorips aims to advance medical treatments through innovation in cell processing and therapeutic applications.

Sho Engineering

Seed Round in 2018
Sho Engineering is a company dedicated to planning, research, and product development in the field of wireless transmission equipment. It specializes in creating innovative technologies aimed at enhancing safety and security in society. The company's offerings include a data transmitter powered by electrical energy from a wireless power transmitter, which facilitates the transmission of data, wireless power, and data transfer. Additionally, Sho Engineering develops devices for long-distance identity cards that utilize microwave radio waves to retrieve information from remote locations. The company also provides an emergency and volcano observation monitoring assistance system, equipping clients with advanced technology to improve safety and situational awareness.

LegalForce

Seed Round in 2018
LegalForce, Inc. is a Tokyo-based company founded in 2017 that specializes in developing software for legal services. It operates an AI-powered contract management platform designed to assist legal professionals in contract review. By utilizing natural language processing and other advanced technologies, LegalForce's platform helps users analyze contracts based on their specific types, while identifying potentially omitted or risky clauses. This functionality aids legal professionals in preventing oversights and enhancing the quality and efficiency of their operations, ultimately strengthening their legal systems.

LegalOn Technologies

Seed Round in 2018
LegalOn Technologies is a prominent provider of AI-driven contract review solutions, serving over 5,000 companies and firms worldwide. Founded in 2017, the company’s platform integrates artificial intelligence with the legal expertise of experienced attorneys, allowing legal teams to review and negotiate contracts up to 85% faster and more accurately. LegalOn's AI identifies potential risks within contracts, generates precise redlines, and adapts to the specific standards and preferences of each organization. This comprehensive solution streamlines various contract-related operations, saving significant time and reducing legal risks. Additionally, LegalOn offers customizable playbooks and an AI assistant that can be accessed online or integrated within Microsoft Word, enhancing the efficiency of legal and business teams. Operating globally, LegalOn has established a strong presence in both the US and Japan.

AFI

Series B in 2018
AFI, established on December 23, 2013, in Seoul, Korea, specializes in innovative technology solutions focused on the food and life science industries. The company manufactures and sells products that utilize advanced inspection and monitoring technologies, including electric filter separation systems and rapid microbiological testing. These solutions are designed to address various needs, particularly in monitoring microbial contamination risks, thereby enhancing food safety for its clients. AFI is committed to environmental sustainability while providing effective and efficient technologies in its sector.

Questetra

Venture Round in 2017
Questetra, Inc. is an enterprise cloud computing company based in Kyoto, Japan, founded in 2008. It specializes in providing business process management (BPM) tools designed to enhance productivity and optimize various workflows for organizations. The Questetra BPM Suite allows users to independently develop and manage BPMN-driven workflows through a 100% web-based interface, enabling both process design and task execution directly in a browser. The platform includes a variety of sample processes, such as estimate generation and invoice issuance, and offers seamless integration with Google Apps, allowing users to log in with their Google accounts and export data to Google Docs. Additionally, Questetra provides BPM consulting services to further support organizations in their process improvement initiatives.

Chordia Therapeutics

Series A in 2017
Chordia Therapeutics Inc. is a clinical-stage biotechnology company based in Fujisawa, Japan, founded in 2017. The company specializes in the research and development of innovative oncology drugs, focusing on delivering first-in-class therapies for cancers that currently have high unmet medical needs. Chordia Therapeutics is committed to advancing new therapeutic options to patients as swiftly as possible, aiming to address significant gaps in cancer treatment.

Thyas

Venture Round in 2017
Thyas Co. Ltd., established in 2015, specializes in developing personalized regenerative immunocell therapies to treat cancer and infections. The company's core business involves generating regenerative T cells from human induced pluripotent stem (iPS) cells, aiming to enhance patients' immune systems for combating various diseases.

Stem Cell & Device Laboratory

Series B in 2017
Stem Cell & Device Laboratory, Inc. is a research and development company based in Kyoto, Japan, focused on the manufacturing and sale of cells, devices, and integrated products that utilize cell materials for drug discovery applications. Founded in 2014, the company specializes in developing innovative scaffold materials that demonstrate functional and cell compatibility, particularly for studies involving pluripotent stem cells. By leveraging advanced micro-engineering and nanofabrication technologies, Stem Cell & Device Laboratory aims to contribute to advancements in cell application products that support the health and well-being of society.

Oligogen

Venture Round in 2017
Oligogen is a bio-venture based in Kyoto, Japan, founded in 2015. The company focuses on drug development and regenerative medicine, specifically utilizing neural stem cell technologies to create therapies for patients with central nervous system diseases. Oligogen aims to treat conditions such as spinal cord injuries and other neurological disorders, including congenital leukoplakia and multiple sclerosis. By harnessing the potential of human neural stem cells, Oligogen seeks to provide effective cell therapies that enhance neurological healthcare for affected individuals.

Thyas

Venture Round in 2017
Thyas Co. Ltd., established in 2015, specializes in developing personalized regenerative immunocell therapies to treat cancer and infections. The company's core business involves generating regenerative T cells from human induced pluripotent stem (iPS) cells, aiming to enhance patients' immune systems for combating various diseases.

Connexx Systems

Venture Round in 2017
Connexx Systems Corporation is a Kyoto-based company that specializes in the development and manufacturing of power storage systems, including household and mobile storage solutions for emergencies. Established in 2011, the company integrates core battery technologies with power generation facilities, utilizing renewable energy sources such as solar and wind power to provide alternative energy solutions. Connexx Systems markets its products through distributors and constructors, as well as through catalogs, offering innovative options for electric power generation and storage. With additional offices in Tokyo and Fukuoka, Connexx Systems aims to enhance energy accessibility and sustainability.

NS Materials

Venture Round in 2017
NS Materials Corp. is a manufacturer and distributor of semiconductor-related equipment and systems, located in Chikushino-shi, Japan. The company focuses on the development of micro-space chemical technologies, particularly in the area of nano-phosphor for LED lighting. Additionally, NS Materials specializes in chemical synthesis technologies that aim to advance nanotechnology and biotechnology. By creating innovative tools and products, the company contributes to the promotion of a low-carbon society and seeks to significantly impact people's lives.

FLOSFIA

Venture Round in 2017
FLOSFIA INC. is a Tokyo-based company that focuses on the development of corundum structured Gallium Oxide semiconductor power devices. Founded on March 31, 2011, the company emerged as a spin-off from research conducted at Kyoto University. FLOSFIA specializes in film-formation using mist chemical vapor deposition (CVD) techniques, leveraging the unique physical properties of gallium oxide (Ga2O3) to create high breakdown voltage and high efficiency power devices. The firm is dedicated to advancing low-loss power device technology, contributing to the evolution of semiconductor applications.

Tiem Factory

Venture Round in 2017
Tiem Factory Inc. is a Tokyo-based company founded in 2012 that specializes in the research, development, manufacturing, and sales of aerogel insulation materials under the brand SUFA. The company focuses on creating ultra-light transparent insulation products that serve as effective thermal insulation solutions. Tiem Factory's innovative approach allows it to produce these materials without the use of supercritical drying processes, resulting in insulation composed primarily of air. This unique manufacturing technique enhances the properties and applications of their insulation products, setting Tiem Factory apart in the industry.

Audio Metaverse

Corporate Round in 2017
Audio Metaverse is a pioneering developer of an audio streaming application that merges physical reality with the virtual realm through innovative 3D audio spaces. The platform, known as Cubemint, allows users to mint NFTs and explore these immersive audio environments collaboratively. It specializes in facilitating real-time conversations among friends and followers, streaming live audio sessions for extended periods while enabling users to respond to comments dynamically. By integrating augmented audio reality, Audio Metaverse enhances the experience of physical spaces through corresponding digital audio environments, allowing users to share and express ideas authentically while interacting with their digital assets.

PrediXT

Seed Round in 2016
PrediXT is a developer of prediction technologies.

Mitsucari

Corporate Round in 2016
Mitsucari is an HR technology service company that specializes in enhancing organizational effectiveness by analyzing individual personalities and compatibility within corporate environments. It has developed a candidate verification platform that assesses job seekers' personalities through aptitude tests while concurrently evaluating existing employees to understand the corporate culture. This dual analysis helps to identify compatibility between candidates and organizations, facilitating better job matching. By focusing on personality traits and desired work conditions, Mitsucari aims to improve the hiring process for employers and assist job seekers in finding positions that align with their values and preferences, ultimately contributing to employee retention and satisfaction.

Lang-8

Venture Round in 2016
Lang-8, Inc. is a Tokyo-based company founded in 2007 that operates a language exchange social networking platform designed to enhance language learning through community interaction. The platform allows users to write journal entries in the language they are learning, which are then corrected by native speakers. This reciprocal learning process enables users to improve their writing skills while also assisting others in their language acquisition. Lang-8 supports over 70 languages and boasts a diverse community of users from 180 countries, fostering a global environment for cultural and linguistic exchange. The company utilizes computer-assisted language learning technology to facilitate this educational experience, making it accessible for learners at various proficiency levels.

KinoPharma

Venture Round in 2016
KinoPharma is a biopharmaceutical company based in Tokyo, Japan, founded in 2005. It specializes in the discovery and development of small molecule drugs targeting Ser/Thr kinases, utilizing proprietary platform technologies. The company collaborates with universities on joint research contracts to develop clinical drugs with minimal side effects, leveraging expertise in phosphoenzyme inhibitor research. KinoPharma focuses on creating therapeutic agents for intractable diseases such as viral infections and neurodegenerative conditions, with a particular emphasis on developing next-generation antiviral drugs for HPV infection, aiming to prevent cervical cancer in women.

Kyoto Drug Discovery & Development

Venture Round in 2016
Kyoto Drug Discovery and Development Co. Ltd., based in Kyoto, Japan, specializes in the development of innovative therapeutic drugs targeting chronic degenerative eye diseases. The company focuses on creating effective treatments for conditions such as glaucoma, central retinal artery occlusion, retinal pigmentosa, and age-related macular degeneration. By addressing these intractable eye diseases, Kyoto Drug Discovery and Development aims to provide healthcare professionals with advanced options to improve patient outcomes and manage debilitating ocular conditions.

AFI

Series A in 2016
AFI, established on December 23, 2013, in Seoul, Korea, specializes in innovative technology solutions focused on the food and life science industries. The company manufactures and sells products that utilize advanced inspection and monitoring technologies, including electric filter separation systems and rapid microbiological testing. These solutions are designed to address various needs, particularly in monitoring microbial contamination risks, thereby enhancing food safety for its clients. AFI is committed to environmental sustainability while providing effective and efficient technologies in its sector.

Stem Cell & Device Laboratory

Series A in 2016
Stem Cell & Device Laboratory, Inc. is a research and development company based in Kyoto, Japan, focused on the manufacturing and sale of cells, devices, and integrated products that utilize cell materials for drug discovery applications. Founded in 2014, the company specializes in developing innovative scaffold materials that demonstrate functional and cell compatibility, particularly for studies involving pluripotent stem cells. By leveraging advanced micro-engineering and nanofabrication technologies, Stem Cell & Device Laboratory aims to contribute to advancements in cell application products that support the health and well-being of society.
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